A practical algorithmic approach to the diagnosis and management of solitary pulmonary nodules: part 1: radiologic characteristics and imaging modalities.

abstract：:Histopathologic and morphometric studies of small pulmonary arteries were performed in 16 cases of secundum atrial septal defect (ASD) and severe pulmonary hypertension. Besides typical plexogenic arteriopathies found in six cases, organized microthrombi and what we call "musculoelastosis," that is, proliferation of l...

journal_title：Chest

authors： Yamaki S,Horiuchi T,Miura M,Suzuki Y,Ishizawa E,Takahashi T

更新日期：1986-05-01 00:00:00

abstract：:Surfactant replacement therapy (SRT) has a proven role in the treatment of neonatal respiratory distress syndrome and severe meconium aspiration syndrome in infants, and may have a role in the treatment of pediatric patients with ARDS. Although newer delivery mechanisms and strategies are being studied, the classic su...

journal_title：Chest

authors： Stevens TP,Sinkin RA

更新日期：2007-05-01 00:00:00

abstract：:Fenoterol hydrobromide (Berotec; formerly Th 1165a) is a sympathomimetic bronchodilator drug. Twenty subjects with mild to moderate reversible bronchospasm completed a double-blind multiple crossover study of single doses of 5 mg, 7.5 mg, and 10 mg of fenoterol hydrobromide, 24 mg of ephedrine, and placebo. Spirometri...

journal_title：Chest

authors： Steen SN,Smith R,Kuo J,Ziment I,Beall G

更新日期：1977-09-01 00:00:00

abstract：BACKGROUND:Increased right ventricular afterload leads to left ventricular diastolic dysfunction due to ventricular interdependence. Increased right ventricular afterload is frequently present in patients with COPD. The purpose of this study was to determine whether left ventricular diastolic dysfunction could be detec...

journal_title：Chest

authors： Funk GC,Lang I,Schenk P,Valipour A,Hartl S,Burghuber OC

更新日期：2008-06-01 00:00:00

abstract：:Cocaine use is associated with adverse events in nearly every organ system. Cardiovascular complications include hemorrhagic and ischemic stroke, aortic dissection, cardiomyopathy, accelerated coronary artery disease, myocardial infarction, and sudden cardiac death. Syncope may be the presenting symptom in these condi...

journal_title：Chest

authors： Castro VJ,Nacht R

更新日期：2000-01-01 00:00:00

abstract：STUDY OBJECTIVES:The purpose of this study was to determine the impact of a multisite implementation of an evidence-based clinical practice guideline for bronchiolitis. DESIGN:Before and after study. SETTING:Eleven Child Health Accountability Initiative (CHAI) study hospitals. PATIENTS:Children < 12 months of age wi...

journal_title：Chest

authors： Kotagal UR,Robbins JM,Kini NM,Schoettker PJ,Atherton HD,Kirschbaum MS

更新日期：2002-06-01 00:00:00

abstract：:The pathogenesis and clinical manifestations of COPD are not restricted to pulmonary inflammation and structural remodeling. Rather, this disorder is associated with clinically significant systemic alterations in biochemistry and organ function. The systemic aspects of COPD include oxidative stress and altered circula...

journal_title：Chest

authors： Wouters EF,Creutzberg EC,Schols AM

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:The effects of regular inhaled beta-agonist treatment on lung function remain a controversial issue. In an earlier study, the administration of regular inhaled salbutamol resulted in negative changes in FEV1 not only in asthmatics, but also in nonasthmatic atopic subjects. OBJECTIVE:The aim of this study wa...

journal_title：Chest

authors： Boothman-Burrell D,Jones D,Herbison GP,Taylor DR

更新日期：1997-07-01 00:00:00

abstract：STUDY OBJECTIVES:We investigated the role of two leukotriene B4 (LTB4) receptors, BLT1 and peroxisome proliferator-activated receptor (PPAR)-alpha, in conferring the susceptibility to develop COPD in smokers. Proinflammatory LTB4 activities are mediated by BLT1, while the inactivation of LTB4 is promoted by PPARalpha. ...

journal_title：Chest

authors： Marian E,Baraldo S,Visentin A,Papi A,Saetta M,Fabbri LM,Maestrelli P

更新日期：2006-06-01 00:00:00

abstract：:Pulmonary hypertension and related pulmonary vascular diseases cause significant morbidities and high mortality and present many unique challenges toward improving outcomes in neonates, infants, and children. Differences between pediatric and adult disease are reflected in controversies regarding etiologies, classific...

journal_title：Chest

authors： Hopper RK,Abman SH,Ivy DD

更新日期：2016-07-01 00:00:00

abstract：OBJECTIVE:We have shown that the administration of 0.8 mg/kg of morphine (M) to patients with COPD resulted in a 20% increase in the maximum oxygen consumption (Vo2max), but was associated with significant drowsiness and euphoria. The objective of the present study was to ascertain whether lower doses of M alone or in ...

journal_title：Chest

authors： Light RW,Stansbury DW,Webster JS

更新日期：1996-04-01 00:00:00

abstract：STUDY OBJECTIVE:Spirometry is performed to monitor lung health, but variability between tests can hinder recognition of excessive FEV(1) declines. We sought to describe the relationship between FEV(1) changes over 1 to 5 years and FEV(1) declines over longer terms, using 21,821 test results from 1,884 workers who parti...

journal_title：Chest

authors： Wang ML,Avashia BH,Petsonk EL

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:There is an increasing demand for home mechanical ventilation (HMV) in patients with chronic respiratory insufficiency. At present, noninvasive ventilation is exclusively initiated in a clinical setting at all four centers for HMV in the Netherlands. In addition to its high societal costs and patient discomf...

journal_title：Chest

authors： van den Biggelaar RJM,Hazenberg A,Cobben NAM,Gaytant MA,Vermeulen KM,Wijkstra PJ

更新日期：2020-12-01 00:00:00

abstract：:Immunoblastic lymphadenopathy presents with fever, malaise, cough, dyspnea, lymphadenopathy, hepatosplenomegaly, hypergammaglobulinemia, interstitial pulmonary infiltrates, mediastinal adenopathy, and effusions. The diagnosis is made on the basis of lymph node biopsy. Based on the course in our patients and the cases ...

journal_title：Chest

authors： Bradley SL,Dines DE,Banks PM,Hill RW

更新日期：1981-09-01 00:00:00

abstract：:Despite major advances in our understanding of the pathophysiologic processes leading to pulmonary arterial hypertension and recent developments in therapeutic approaches, the long-term prognosis for patients with pulmonary arterial hypertension remains unsatisfactory. Early detection and adequate clinical classificat...

journal_title：Chest

authors： Provencher S,Jais X,Yaici A,Sitbon O,Humbert M,Simonneau G

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:A multicenter study in the late 1990s demonstrated suboptimal emergency asthma care for pregnant women in US EDs. After a decade, follow-up data are lacking. We aimed to examine changes in emergency asthma care of pregnant women since the 1990s. METHODS:We combined data from four multicenter observational s...

journal_title：Chest

authors： Hasegawa K,Cydulka RK,Sullivan AF,Langdorf MI,Nonas SA,Nowak RM,Wang NE,Camargo CA Jr

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:Matrix metalloproteinase (MMP)-7 was reported to be a key molecule in the pathogenesis of idiopathic pulmonary fibrosis (IPF) based on the result of microarray analysis and knockout mice. However, the role of MMP-7 has not been determined in other types of idiopathic interstitial pneumonia (IIP). The aim of ...

journal_title：Chest

authors： Huh JW,Kim DS,Oh YM,Shim TS,Lim CM,Lee SD,Koh Y,Kim WS,Kim WD,Kim KR

更新日期：2008-05-01 00:00:00

abstract：:The dynamics of cerebral blood flow velocity (CBFV) during sleep were investigated in the right middle cerebral artery of 10 patients with sleep apnea syndrome (SAS) (mean age, 37 years) and 10 healthy control subjects (mean age, 32 years) throughout the entire sleep period. A computer-assisted pulsed (2 MHz) transcra...

journal_title：Chest

authors： Hajak G,Klingelhöfer J,Schulz-Varszegi M,Sander D,Rüther E

更新日期：1996-09-01 00:00:00

abstract：:Central hemodynamics and gas exchange were studied in six patients with chronic obstructive pulmonary disease (mean age, 60 years). Patients were selected for the study if the volume of blood was 1 L larger than the predicted normal value, if there was no history of infection, and if no drug assumed to influence pulmo...

journal_title：Chest

authors： Gertz I,Hedenstierna G,Wester PO

更新日期：1979-02-01 00:00:00

abstract：STUDY OBJECTIVES:The prevalence of gastroesophageal reflux disease (GERD) is higher in people with asthma than in control populations. Predisposing factors for GERD development may include asthma medications such as prednisone. The objective of this study was to determine whether prednisone alters GERD parameters in pe...

journal_title：Chest

authors： Lazenby JP,Guzzo MR,Harding SM,Patterson PE,Johnson LF,Bradley LA

更新日期：2002-02-01 00:00:00

abstract：:The ventilatory effects of a bolus intravenous dose of doxapram (0.37 to 0.47 mg/kg) were studied in ten healthy normal subjects. An immediate significant (p less than 0.001) increase in minute ventilation (VE) was due, in equal part, to significant increases in tidal volume (VT) and frequency (f). The inspiratory (TI...

journal_title：Chest

authors： Burki NK

更新日期：1984-05-01 00:00:00

abstract：:Endobronchial tuberculosis, while relatively common before the advent of effective antituberculosis chemotherapy, is seldom recognized now. Four patients with what appeared to be primary tuberculosis complicated by endobronchial spread were recently seen by us. Three of the four patients presented with anterior segmen...

journal_title：Chest

authors： Matthews JI,Matarese SL,Carpenter JL

更新日期：1984-10-01 00:00:00

abstract：BACKGROUND:Many lung transplant programs employ lengthy regimens of IV ganciclovir therapy to prevent disease due to cytomegalovirus (CMV). In 1994, we introduced a regimen of delayed ganciclovir prophylaxis for CMV infection. This consisted of 2 weeks of IV ganciclovir therapy, initiated 3 to 4 weeks after transplanta...

journal_title：Chest

authors： Brumble LM,Milstone AP,Loyd JE,Ely EW,Pierson RN 3rd,Gautam S,Dummer JS

更新日期：2002-02-01 00:00:00

abstract：OBJECTIVES:The objectives of this study were to determine the prevalence of Aspergillus fumigatus and Candida albicans in the sputa of patients with cystic fibrosis (CF), to assess serologic IgE responses of these patients to the presence of fungi in the sputum, to evaluate what effect this may have on clinical status,...

journal_title：Chest

authors： Máiz L,Cuevas M,Quirce S,Cañón JF,Pacheco A,Sousa A,Escobar H

更新日期：2002-03-01 00:00:00

abstract：:The efficacy of a new tissue-culture technique for the diagnosis of malignant pleural effusions was contrasted with conventional cytologic methods. The new technique is based on the ability of the tissue-culture medium to transform mesothelial cells into fibroblasts while not sustaining lymphoreticular cells. Against ...

journal_title：Chest

authors： Monif GR,Stewart BN,Block AJ

更新日期：1976-05-01 00:00:00

abstract：STUDY OBJECTIVES:To assess the effectiveness of pulse oximetry and radioisotope measurement of right-to-left (R-L) shunt for the early detection of pulmonary arteriovenous malformations (PAVMs) in patients with hereditary hemorrhagic telangiectasia (HHT). DESIGN:Patients with HHT had serial measurements of the followi...

journal_title：Chest

authors： Thompson RD,Jackson J,Peters AM,Doré CJ,Hughes JM

更新日期：1999-01-01 00:00:00

abstract：:Thirty-eight high-risk patients (forced expiratory volume in one second [FEV1] less than 2.0L or maximum voluntary ventilation [MVV] less than 50 per cent of predicted) were observed for a minimum of one year after pneumonectomy for carcinoma of the lung. Operability was assessed by calculating a predicted postoperati...

journal_title：Chest

authors： Boysen PG,Harris JO,Block AJ,Olsen GN

更新日期：1981-08-01 00:00:00

abstract：BACKGROUND:The use of both heroin and cocaine has been associated with asthma exacerbations. However, the magnitude of this effect has not been adequately described. The purpose of this study was to examine the association between cocaine or heroin use and asthma severity. METHODS:We conducted a retrospective chart re...

journal_title：Chest

authors： Levine M,Iliescu ME,Margellos-Anast H,Estarziau M,Ansell DA

更新日期：2005-10-01 00:00:00

abstract：:This prospective study compared two weaning modalities in COPD patients requiring mechanical ventilation (MV) for acute respiratory failure. Nineteen patients with COPD were studied when their precipitating illness was controlled. Although they satisfied the conventional bedside weaning criteria, they could not tolera...

journal_title：Chest

authors： Jounieaux V,Duran A,Levi-Valensi P

更新日期：1994-04-01 00:00:00

abstract：:Systolic ejection clicks, often associated with cardiac disease, can be distinguished from mid-systolic clicks of mitral and tricuspid origin, which are frequently benign. A different mid-systolic sound has been recognized, with timing similar to the mid-systolic clicks, which is associated with aortic insufficiency. ...

journal_title：Chest

authors： Robertson WS,Tavel ME

更新日期：1983-01-01 00:00:00