Up-regulated membrane and nuclear leukotriene B4 receptors in COPD.

abstract：BACKGROUND:The longitudinal associations between depression or anxiety and COPD, and their comorbid effect on prognosis, have not been adequately addressed by previous reviews. We aimed to systematically assess these associations to inform guidelines and practice. METHODS:We searched electronic databases for articles ...

journal_title：Chest

authors： Atlantis E,Fahey P,Cochrane B,Smith S

更新日期：2013-09-01 00:00:00

abstract：:A CO2 rebreathing method for the measurement of cardiac output was evaluated by comparison with the direct Fick O2 method in 26 studies performed in 18 patients who were critically ill. The method requires measurement of CO2 output by collection of expired gas, of arterial PCO2, and of mixed venous PCO2 by rebreathing...

journal_title：Chest

authors： Davis CC,Jones NL,Sealey BJ

更新日期：1978-02-01 00:00:00

abstract：:Men who snore heavily have an increased incidence of hypertension, angina, stroke, and neuropsychologic dysfunction, which may be due to nocturnal oxygen desaturation. Nocturnal oxygen therapy might be beneficial to such individuals by improving oxygenation and relieving tissue hypoxia. Twenty-eight asymptomatic heavy...

journal_title：Chest

authors： Block AJ,Hellard DW,Cicale MJ

更新日期：1987-09-01 00:00:00

abstract：STUDY OBJECTIVE:To determine how the volume and severity of emphysema measured by CT morphometry (CTM) before and after lung volume reduction surgery (LVRS) relates to the functional status of patients after LVRS. DESIGN:A histologically validated CT algorithm was used to quantify the volume and severity of emphysema ...

journal_title：Chest

authors： Rogers RM,Coxson HO,Sciurba FC,Keenan RJ,Whittall KP,Hogg JC

更新日期：2000-11-01 00:00:00

abstract：:It has been observed that T-lymphocytes of patients with tuberculosis produce interferon gamma (IFN gamma) in vitro. Based on this idea, we studied IFN gamma in pleural fluid and serum. We studied 80 patients with pleural effusion; 30 patients with tuberculous pleurisy had high IFN gamma concentrations in pleural flui...

journal_title：Chest

authors： Ribera E,Ocaña I,Martinez-Vazquez JM,Rossell M,Español T,Ruibal A

更新日期：1988-02-01 00:00:00

abstract：:Although the principal actions of clonidine are linked to its centrally mediated suppression of sympathetic activity, its inhibition of the renin axis also may contribute to its antihypertensive effects. In patients with essential hypertension studied in a clinical research center, clonidine-induced decreases in diast...

journal_title：Chest

authors： Weber MA,Drayer JI,Hubbell FA

更新日期：1983-02-01 00:00:00

abstract：BACKGROUND:Induced sputum cytology and protein biomarkers can be used to assess airways inflammation. Increases in sputum iron have been described in inflammatory lung disease. We hypothesized that other sputum metals may be affected by airways inflammation and investigated their potential value as biomarkers. METHODS...

journal_title：Chest

authors： Gray RD,Duncan A,Noble D,Imrie M,O'Reilly DS,Innes JA,Porteous DJ,Greening AP,Boyd AC

更新日期：2010-03-01 00:00:00

abstract：:The mechanisms leading to rapid changes in arterial blood gas values soon after exercise ends have not been well established. To further study these phenomena, we exercised seven normal male volunteers to exhaustion on a cycle ergometer with a 25-W/min ramped protocol measuring arterial blood gas values, and breath-by...

journal_title：Chest

authors： O'Neill AV,Johnson DC

更新日期：1991-05-01 00:00:00

abstract：:The authors believe this to be the first case report of atrial fibrillation following pulse methylprednisolone therapy in an adult. The literature regarding the complications of pulse methylprednisolone therapy is reviewed, with particular emphasis on the incidence and pathogenesis of arrhythmias. ...

journal_title：Chest

authors： McLuckie AE,Savage RW

更新日期：1993-08-01 00:00:00

abstract：STUDY OBJECTIVES:Direct current (DC) shocks to the heart cause morphologic and functional myocardial damage. Previous studies have suggested that acute DC shock injury is free radical mediated and that the administration of antioxidant enzymes superoxide dismutase and catalase can reduce the level of DC shock-induced f...

journal_title：Chest

authors： Pagan-Carlo LA,Garcia LA,Hutchison JL,Buettner GR,Kerber RE

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND:Asthma is a worldwide problem. It cannot be prevented or cured, but it is possible, at least in principle, to control asthma with modern management. Control usually is assessed by history of symptoms, physical examination, and measurement of lung function. A practical problem is that these measures of contro...

journal_title：Chest

authors： Green RJ,Klein M,Becker P,Halkas A,Lewis H,Kitchin O,Moodley T,Masekela R

更新日期：2013-01-01 00:00:00

abstract：STUDY OBJECTIVE:To determine if a training session using videotaped metered dose inhaler (MDI) performances can result in high interrater and intrarater reliability of five evaluators assessing MDI technique. DESIGN:Five evaluators (three pharmacists, two pulmonary fellows) were trained to evaluate MDI technique durin...

journal_title：Chest

authors： Gray SL,Nance AC,Williams DM,Pulliam CC

更新日期：1994-03-01 00:00:00

abstract：:Because T-piece breathing may impair oxygenation, the best airway pressure from which to extubate ventilated patients is controversial. We compared the effects of extubation after 1 h of either CPAP 5 and T-piece/ZEEP. Once weaned from mechanical ventilation and breathing spontaneously, 106 patients were randomized to...

journal_title：Chest

authors： Jones DP,Byrne P,Morgan C,Fraser I,Hyland R

更新日期：1991-12-01 00:00:00

abstract：BACKGROUND:While the beneficial effect of exercise capacity on mortality is well-accepted, its effect on health-care costs remains uncertain. This study investigates the relationship between exercise capacity and health-care costs. METHODS:The Veterans Affairs Health Care System recently implemented a Decision Support...

journal_title：Chest

authors： Weiss JP,Froelicher VF,Myers JN,Heidenreich PA

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:The clinical course of idiopathic pulmonary fibrosis (IPF) is characterized by progressive decline in lung function and eventual mortality. We sought to determine if future declines in pulmonary function, mortality, or both can be predicted from prior trends in pulmonary function tests (PFTs). METHODS:Data ...

journal_title：Chest

authors： Schmidt SL,Tayob N,Han MK,Zappala C,Kervitsky D,Murray S,Wells AU,Brown KK,Martinez FJ,Flaherty KR

更新日期：2014-03-01 00:00:00

abstract：:Bronchopulmonary C-fibers and a subset of mechanically sensitive, acid-sensitive myelinated sensory nerves play essential roles in regulating cough. These vagal sensory nerves terminate primarily in the larynx, trachea, carina, and large intrapulmonary bronchi. Other bronchopulmonary sensory nerves, sensory nerves inn...

journal_title：Chest

authors： Canning BJ,Chang AB,Bolser DC,Smith JA,Mazzone SB,McGarvey L,CHEST Expert Cough Panel.

更新日期：2014-12-01 00:00:00

abstract：:Occupational exposure to aerosolized pentamidine has raised questions regarding transmission of tuberculosis and the effect of the drug itself. To estimate the exposure of a health care worker, we measured the ambient concentration of aerosolized pentamidine in field conditions in 36 m3 unventilated treatment room. Th...

journal_title：Chest

authors： Montgomery AB,Corkery KJ,Brunette ER,Leoung GS,Waskin H,Debs RJ

更新日期：1990-08-01 00:00:00

abstract：:Among 1,700 primary tumors of the lung, there were 53 cases of bronchial adenoma (3.1 percent); 38 (72 percent) of the 53 were typical carcinoids, and the remaining 15 were of a higher grade of malignant neoplasm. There was a slight predominance of female patients, and the age of greatest incidence was between 30 and ...

journal_title：Chest

authors： de Lima R

更新日期：1980-01-01 00:00:00

abstract：:Pulmonary function studies were performed before and after one-time administration of an inhaled bronchodilator to ascertain the relative diagnostic value of using FVC, FEF25-75%, static lung volumes, Raw, and/or sGaw measurements, in addition to the FEV1, to assess the reversibility of chronic airways obstruction in ...

journal_title：Chest

authors： Berger R,Smith D

更新日期：1988-03-01 00:00:00

abstract：STUDY OBJECTIVE:We have previously investigated the effects of microphone type and coupler air chamber depth on lung sound characteristics. We now report the results of experiments exploring the effects of air chamber width, shape, and venting on lung sounds. DESIGN:We used a single electret microphone with a variety ...

journal_title：Chest

authors： Kraman SS,Wodicka GR,Oh Y,Pasterkamp H

更新日期：1995-10-01 00:00:00

abstract：:We wanted to determine the long-term effects of a continuous infusion of PGE1 on DO2 and VO2 in patients with ARDS. Data were obtained from a randomized double-blind multicenter trial, which evaluated the effects of PGE1 on survival in patients with ARDS. Patients were stratified according to treatment and outcome: pl...

journal_title：Chest

authors： Silverman HJ,Slotman G,Bone RC,Maunder R,Hyers TM,Kerstein MD,Ursprung JJ

更新日期：1990-08-01 00:00:00

abstract：BACKGROUND:Strong evidence exists for clinically relevant night-to-night variability of respiratory events in patients with suspected OSA. RESEARCH QUESTION:How many sleep study nights are required to diagnose OSA accurately? STUDY DESIGN AND METHODS:Patients with suspected OSA underwent up to 14 nights of pulse oxim...

journal_title：Chest

authors： Roeder M,Sievi NA,Bradicich M,Grewe F,Siegfried S,Gaisl T,Kohler M

更新日期：2020-09-25 00:00:00

abstract：:Between November, 1965 and June, 1970, 175 patients underwent mitral valve replacement with the Smeloff-Cutter prosthesis (109 patients) or the toroidal valve (66 patients). The early mortality for patients with a toroidal mitral prosthesis was 18.2 percent (12 patients) and the late mortality 34.8 percent (23 patient...

journal_title：Chest

authors： Rees JR,Holswade GR,Carlson RG,Subramanian VA,Murphy TE,Lillehei CW

更新日期：1977-02-01 00:00:00

abstract：:The contemporary surgical repertoire for the evaluation and treatment of patients with lung cancer includes the bronchoscope, mediastinoscope, thoracoscope, and standard surgical instrumentation. The recent advances in video optics and the development of endoscopic instruments have significantly expanded the surgical ...

journal_title：Chest

authors： Mentzer SJ,DeCamp MM,Harpole DH Jr,Sugarbaker DJ

更新日期：1995-06-01 00:00:00

abstract：:Irwin and co-workers have designed an anatomic approach to the diagnosis and treatment of cough. In their hands, diagnosis was consistently determined and treatment successful almost without exception, if sustained. We reviewed the results of a similar approach in 139 consecutive and unselected patients referred to pu...

journal_title：Chest

authors： Poe RH,Harder RV,Israel RH,Kallay MC

更新日期：1989-04-01 00:00:00

abstract：BACKGROUND:Tobacco smoke is a major risk factor in the development of COPD. Secondhand smoke (SHS) exposure is a known risk factor in asthma, bronchitis, and coronary artery disease. Elastin is a recognized target for injury in COPD, and the amino acids desmosine and isodesmosine (D/I), which are specific for elastin d...

journal_title：Chest

authors： Slowik N,Ma S,He J,Lin YY,Soldin OP,Robbins RA,Turino GM

更新日期：2011-10-01 00:00:00

abstract：:Postoperative bronchial stump failure is a life-threatening complication, and several surgical approaches and procedures have been developed to close the stump. In this report, we describe a case of left mainstem bronchial stump diastasis after pneumonectomy for lung cancer, in which the bronchial stump was re-closed ...

journal_title：Chest

authors： Tsunezuka Y,Sato H,Kodama T

更新日期：2000-03-01 00:00:00

abstract：:Postinfluenza toxic shock syndrome is a recently described entity that results from a respiratory tract infection with toxin-producing Staphylococcus aureus following an episode of influenza or influenzalike illness. This report describes a 19-year-old man who developed an influenza B respiratory infection complicated...

journal_title：Chest

authors： Prechter GC,Gerhard AK

更新日期：1989-05-01 00:00:00

abstract：:Human genetic variation has enormous implications for individual susceptibility to lung disease, as well as for differences in prognosis and response to therapeutic interventions. Single-nucleotide polymorphisms (SNPs) are the most common type of DNA sequence variation. An SNP is the substitution of a single base in t...

journal_title：Chest

authors： Tebbutt SJ,James A,Paré PD

更新日期：2007-04-01 00:00:00

abstract：:The influence of positive expiratory pressure (PEP) applied during inhalation of a beta 2-agonist in treatment of bronchial asthma was investigated in a randomized crossover study with two-week treatment periods. In one period, two puffs (0.5 mg) of terbutaline was given from a metered dose inhaler and inhaled through...

journal_title：Chest

authors： Frischknecht-Christensen E,Nørregaard O,Dahl R

更新日期：1991-08-01 00:00:00