Single-nucleotide polymorphisms and lung disease: clinical implications.

abstract：:A 36-year-old man with a history of hypertrophic obstructive cardiomyopathy presented to the emergency room with "stabbing" chest pain. He had undergone dual-chamber pacemaker implantation in 1993 using an atrial lead (Accufix; Telectronics; Englewood, Colo) and a myomectomy in 1996 during which the distal portion of ...

journal_title：Chest

authors： Gerstenfeld EP,Balarajan Y,Cooke R,Mittleman RS

更新日期：1998-08-01 00:00:00

abstract：:Indirect evidence from airway pressure recordings in mechanically ventilated patients suggests that the diaphragm exhibits contractile activity beyond that required to trigger a ventilator-assisted breath. We used the diaphragmatic EMG to provide direct evidence of persistent contractile activity and studied the effec...

journal_title：Chest

authors： Flick GR,Bellamy PE,Simmons DH

更新日期：1989-07-01 00:00:00

abstract：:Pulmonary rejection and infection are the most important complications after lung transplantation. To evaluate the diagnostic value of pulmonary function testing for early detection and discrimination of these complications, seven heart-lung recipients were examined. The diagnosis of each complication was confirmed by...

journal_title：Chest

authors： Hoeper MM,Hamm M,Schäfers HJ,Haverich A,Wagner TO

更新日期：1992-09-01 00:00:00

abstract：:The diagnosis of aortic ring abscess by cross-sectional echocardiography has not been reported. In this paper, a case of bacterial endocarditis of the aortic valve extending to the aortic ring and the mitral valve is reported. The role of cross-sectional echocardiography in defining the anatomic distortion of the aort...

journal_title：Chest

authors： Mardelli TJ,Ogawa S,Hubbard FE,Dreifus LS,Meixell LL

更新日期：1978-11-01 00:00:00

abstract：STUDY OBJECTIVE:The purpose of this study was to evaluate the diagnostic value of low voltage with PR-segment and ST-T wave changes in determining the amount of clinically silent pericardial effusion detected in a routine echocardiography. DESIGN:Consecutive case series analysis. SETTING:Noninvasive cardiology depart...

journal_title：Chest

authors： Kudo Y,Yamasaki F,Doi T,Doi Y,Sugiura T

更新日期：2003-12-01 00:00:00

abstract：:We describe three cases of acute uncomplicated bacterial pneumonia due to viridans streptococci in previously healthy adults, which were indistinguishable from those caused by other well-known respiratory pathogens. On arrival, all of these patients were treated with IV aqueous penicillin based on Gram stain of sputum...

journal_title：Chest

authors： Sarkar TK,Murarka RS,Gilardi GL

更新日期：1989-10-01 00:00:00

abstract：BACKGROUND:IV fluid represents a basic therapeutic intervention for septic shock. Unfortunately, the optimal administration of IV fluid to maximize patient outcomes and prevent complications is largely unknown. METHODS:Patients with septic shock admitted to the medical ICUs of Barnes-Jewish Hospital (January to Decemb...

journal_title：Chest

authors： Chen C,Kollef MH

更新日期：2015-12-01 00:00:00

abstract：:We are probably observing a recrudescent epidemic of RLF which has elicited surprisingly little attention from the medical community. Given present data, it is not unreasonable to conclude that there is a true epidemic and that its etiologic basis involves a population of infants with high susceptibility to oxygen tox...

journal_title：Chest

authors： Robin ED,Burke CM

更新日期：1986-04-01 00:00:00

abstract：STUDY OBJECTIVES:Pacing-induced asynchrony may deteriorate left ventricular function; however, limited data exists in humans. The aim of our study was to compare left ventricular hemodynamics during short-term atrioventricular sequential pacing from the right ventricular apex and from the outflow tract of the right ven...

journal_title：Chest

authors： Kolettis TM,Kyriakides ZS,Tsiapras D,Popov T,Paraskevaides IA,Kremastinos DT

更新日期：2000-01-01 00:00:00

abstract：:Auditors in Medicare overpayment or False Claims Act (FCA) cases often use statistical extrapolation to estimate a health-care provider's total liability from a small sample of audited claims. Courts treat statistical extrapolation differently depending on the context. They generally afford the government substantial ...

journal_title：Chest

authors： Salcido R,Rubin E

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:Patients with malignant pleural effusion (MPE) have limited prognoses. They require long-lasting symptom relief with minimal hospitalization. Indwelling pleural catheters (IPCs) and talc pleurodesis are approved treatments for MPE. Establishing the implications of IPC and talc pleurodesis on subsequent hospi...

journal_title：Chest

authors： Fysh ETH,Waterer GW,Kendall PA,Bremner PR,Dina S,Geelhoed E,McCarney K,Morey S,Millward M,Musk AWB,Lee YCG

更新日期：2012-08-01 00:00:00

abstract：:We report the clinical history, laboratory findings, and imaging features of coronavirus disease 2019 (COVID-19) in a neonate whose mother was also a patient. The newborn was the youngest patient with COVID-19 in the world at the time he was diagnosed. This case has brought more attention and understanding to the epid...

journal_title：Chest

authors： Xiong Y,Zhang Q,Zhao L,Shao J,Zhu W

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Many lung transplant programs employ lengthy regimens of IV ganciclovir therapy to prevent disease due to cytomegalovirus (CMV). In 1994, we introduced a regimen of delayed ganciclovir prophylaxis for CMV infection. This consisted of 2 weeks of IV ganciclovir therapy, initiated 3 to 4 weeks after transplanta...

journal_title：Chest

authors： Brumble LM,Milstone AP,Loyd JE,Ely EW,Pierson RN 3rd,Gautam S,Dummer JS

更新日期：2002-02-01 00:00:00

abstract：:Actinomyces israelii is a rare cause of pericarditis. Infection spreads to pericardium from an intrathoracic focus. Branching gram-positive filaments are seen on microscopic examination of clinical specimens. Cultures should be performed under anaerobic conditions. Both surgical drainage and antibiotics (penicillin) a...

journal_title：Chest

authors： Schlossberg D,Franco-Jove D,Woodward C,Shulman J

更新日期：1976-05-01 00:00:00

abstract：BACKGROUND:It is unknown if the radiographic fibrosis score predicts mortality in persistent hypersensitivity pneumonitis (HP) and if survival is similar to that observed in idiopathic pulmonary fibrosis (IPF) when adjusting for the extent of radiographic fibrosis. METHODS:We reviewed records from 177 patients with HP...

journal_title：Chest

authors： Mooney JJ,Elicker BM,Urbania TH,Agarwal MR,Ryerson CJ,Nguyen MLT,Woodruff PG,Jones KD,Collard HR,King TE Jr,Koth LL

更新日期：2013-08-01 00:00:00

abstract：:The benefit of noninvasive pressure support ventilation (NIPSV) in avoiding the need for endotracheal intubation and reducing morbidity and mortality associated with endotracheal intubation was evaluated in 41 patients who presented with acute respiratory failure not related to chronic obstructive pulmonary disease (C...

journal_title：Chest

authors： Wysocki M,Tric L,Wolff MA,Millet H,Herman B

更新日期：1995-03-01 00:00:00

abstract：:A patient with unruptured congenital aneurysm of the left coronary sinus of Valsalva presented with acute right-sided heart failure due to right ventricular outflow tract obstruction. The mechanism for such an acute presentation may have been a sudden increase in the size of the aneurysm. The surgical importance of th...

journal_title：Chest

authors： D'Silva SA,Dalvi BV,Lokhandwala YY,Kale PA,Tendolkar AG

更新日期：1992-02-01 00:00:00

abstract：:The chest radiograph of a woman with acute asthma showed signs of obstructive emphysema of the left lung. Fiberoptic bronchoscopy excluded obstruction of a large bronchus. The signs disappeared after antiasthmatic treatment, suggesting that they were caused by airway closure. In usual asthma, airway closure affects bo...

journal_title：Chest

authors： DiFrancia M,Barbier D,Orehek J

更新日期：1993-12-01 00:00:00

abstract：:An asymptomatic young man presented with a cardiac murmur and hypertension only in the right arm. Angiograms showed kinking of the aortic arch with a figure-eight appearance consistent with pseudocoarctation. Before the kinked segment, also demonstrated were a stenotic lesion in the aortic arch proximal to the left ca...

journal_title：Chest

authors： Tsai LM,Fu M,Chang CH,Hung JS

更新日期：1990-05-01 00:00:00

abstract：:A 51-year-old man suffered third-degree caustic burns of the esophagus and proximal two-thirds of the stomach. A tracheoesophageal fistula developed, and surgery was performed to exclude the esophagus from gastrointestinal reflux and to divert the oral secretions. An uneventful postoperative course was interrupted on ...

journal_title：Chest

authors： Singh AK,Kothawla LK,Karlson KE

更新日期：1976-10-01 00:00:00

abstract：:Direct mechanical ventricular actuation (DMVA) is a non-blood-contacting method of biventricular cardiac massage which may be applied expediently for total circulatory support. The purpose of this study was to assess the feasibility of DMVA application for patients suffering refractory cardiac arrest. Following inform...

journal_title：Chest

authors： Anstadt MP,Bartlett RL,Malone JP,Brown GR,Martin S,Nolan DJ,Oberheu KH,Anstadt GL

更新日期：1991-07-01 00:00:00

abstract：:The presented data suggest that PAPase may, indeed, be important in the biosynthesis of lung phospholipids. The observed increase in the specific activity of rabbit lung precedes the "surge" of phosphatidylcholine concentration and surfactant biosynthesis by at least 24 hours. In human amnionic fluid, PAPase specific ...

journal_title：Chest

authors： Johnston JM,Schultz M,Jimenez JM,MacDonald PC

更新日期：1975-02-01 00:00:00

abstract：:Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and usually fatal disease, based on a multifaceted and incompletely understood pathogenesis. Some of the cellular and molecular mechanisms of vascular remodeling have been experimentally explored, and it is obvious that alterations of microvessels are invo...

journal_title：Chest

authors： Hanumegowda C,Farkas L,Kolb M

更新日期：2012-07-01 00:00:00

abstract：:Hospitalizations for patients with acute exacerbations of COPD are associated with several adverse patient outcomes as well as with significant health-care costs. Despite many interventions targeted at reducing readmissions following an initial hospitalization, there are few strategies that have been consistently asso...

journal_title：Chest

authors： Freedman N

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVE:To describe and correlate pulmonary function and high-resolution CT (HRCT) scan scores in individuals with a high risk for development of pulmonary fibrosis, ie, Hermansky-Pudlak syndrome (HPS) patients with mutations in the HPS-1 gene. DESIGN:Cross-sectional analysis of consecutive, eligible patients. PATI...

journal_title：Chest

authors： Brantly M,Avila NA,Shotelersuk V,Lucero C,Huizing M,Gahl WA

更新日期：2000-01-01 00:00:00

abstract：:Eradication of the bacterial pathogen, resolution of the local and systemic inflammatory signs, and recovery of organ function are the main criteria by which antibiotic treatment is evaluated. In cystic fibrosis (CF) the pathogen is seldom eradicated and systemic markers of inflammation are not always present. The mai...

journal_title：Chest

authors： Levy J

更新日期：1988-08-01 00:00:00

abstract：STUDY OBJECTIVES:Patients with COPD have an increased sympathetic modulation and reduced baroreflex sensitivity (BRS). Therefore, we studied the effects of breathing 31% supplemental oxygen (SuppO(2)) on autonomic modulation in a group of COPD patients. DESIGN:We measured autonomic modulation before and during the adm...

journal_title：Chest

authors： Bartels MN,Gonzalez JM,Kim W,De Meersman RE

更新日期：2000-09-01 00:00:00

abstract：:Nearly all patients with pulmonary embolism (PE) have complete clinical and hemodynamic and at least near complete roentgenographic and angiographic resolution within four to six weeks of the acute event. To classify the syndrome of unresolved pulmonary embolism we reviewed our experience and that of the English liter...

journal_title：Chest

authors： Benotti JR,Ockene IS,Alpert JS,Dalen JE

更新日期：1983-12-01 00:00:00

abstract：:This study demonstrates that when the heart is markedly displaced posteriorly to the left, or perhaps to the right, the posterior approach may make echocardiographic evaluation possible. Thus, in a patient with congenital unilateral absence of the left pulmonary artery, with marked displacement of the heart posteriorl...

journal_title：Chest

authors： Borgeson E,Vogel JH

更新日期：1980-01-01 00:00:00

abstract：:Continuous measurement of mixed venous oxygen saturation (SvO2) has been suggested as an adjunct in monitoring critically ill patients. We evaluated SvO2 monitoring in 24 patients suffering from complicated myocardial infarctions. Cardiac output and arterial lactate levels were measured when there were persistent 5 pe...

journal_title：Chest

authors： Kyff JV,Vaughn S,Yang SC,Raheja R,Puri VK

更新日期：1989-03-01 00:00:00