Abstract:
:Men who snore heavily have an increased incidence of hypertension, angina, stroke, and neuropsychologic dysfunction, which may be due to nocturnal oxygen desaturation. Nocturnal oxygen therapy might be beneficial to such individuals by improving oxygenation and relieving tissue hypoxia. Twenty-eight asymptomatic heavy snoring men were recruited for polysomnographic monitoring during sleep. During the first half-night, air was breathed through a nasal cannula, and during the latter half-night, 2 L/min oxygen was administered. Breathing air, 20 subjects demonstrated sleep apneas, hypopneas and nocturnal oxygen desaturation. Eighteen subjects had more than ten apneas plus hypopneas per hour. Thirteen subjects reached low oxygen saturation below 80 percent and eight below 70 percent. Only 13 of the 20 subjects showed improvement with oxygen therapy. Apneas alone were not decreased in frequency and were lengthened with oxygen therapy. Episodes of oxygen desaturation were improved by oxygen therapy and consequently, rates of hypopnea were decreased. Severe sleep apnea, hypopnea and oxygen desaturation are common in asymptomatic male snorers, and oxygen therapy is not always beneficial.
journal_name
Chestjournal_title
Chestauthors
Block AJ,Hellard DW,Cicale MJdoi
10.1378/chest.92.3.411subject
Has Abstractpub_date
1987-09-01 00:00:00pages
411-7issue
3eissn
0012-3692issn
1931-3543pii
S0012-3692(15)43532-9journal_volume
92pub_type
杂志文章相关文献
CHEST文献大全abstract::Two patients with schistosomal cor pulmonale and central cyanosis were studied by contrast-enhanced echocardiography, using indocyanine green injection. Intrapulmonary shunts were detected by this method. To our knowledge, this is the first report that proves the presence of intrapulmonary shunts in schistosomal cor p...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.104.4.1280
更新日期:1993-10-01 00:00:00
abstract:STUDY OBJECTIVES:Whereas pulmonary rehabilitation reduces symptoms and improves the quality of life of patients with COPD and is recommended in management guidelines, few patients have access to rehabilitation services. The purpose of this study was to investigate the effectiveness of increasing access to selected comp...
journal_title:Chest
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1378/chest.128.4.2017
更新日期:2005-10-01 00:00:00
abstract::Systemically bioavailable leukotriene receptor antagonists (LTRAs) can reduce the essential components of allergic inflammation in allergic rhinitis (AR) and asthma by blocking cysteinyl leukotriene (CysLT) activity, resulting in a wide range of clinical effects. CysLTs, mediators, and modulators in the pathophysiolog...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1378/chest.127.4.1312
更新日期:2005-04-01 00:00:00
abstract::The call for meaningful patient and family engagement in research has recently gained considerable momentum. This article defines patient and family engagement broadly and specifically in clinical research. Using a multicenter, North American weaning trial as an exemplar, we describe our early experiences as clinical ...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1016/j.chest.2017.06.028
更新日期:2017-10-01 00:00:00
abstract:STUDY OBJECTIVES:To ascertain whether inspiratory pressure support (IPS) can be triggered reliably from and targeted at esophageal pressures (Pes), and to compare the work of breathing and time delay to initiation of inspiratory flow between conventional pressure support and esophageal-directed pressure support (EDPS)....
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.115.2.482
更新日期:1999-02-01 00:00:00
abstract::Endobronchial tuberculosis, while relatively common before the advent of effective antituberculosis chemotherapy, is seldom recognized now. Four patients with what appeared to be primary tuberculosis complicated by endobronchial spread were recently seen by us. Three of the four patients presented with anterior segmen...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.86.4.642
更新日期:1984-10-01 00:00:00
abstract:BACKGROUND:This study reports the effect of thoracentesis on respiratory mechanics and gas exchange in patients receiving mechanical ventilation. STUDY DESIGN:Prospective. SETTING:University hospital. PATIENTS:Eight patient receiving mechanical ventilation with unilateral (n = 7) or bilateral (n = 1) large pleural e...
journal_title:Chest
pub_type: 临床试验,杂志文章
doi:10.1378/chest.130.5.1354
更新日期:2006-11-01 00:00:00
abstract::In the case reported, a patient with severe right ventricular failure following coronary revascularization was successfully weaned from cardiopulmonary bypass following creation of an atrial septal defect. This technique facilitated rapid decompression of the failing right ventricle by shunting blood to the more compl...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.92.5.950
更新日期:1987-11-01 00:00:00
abstract::Residual volume (RV) was obtained by subtracting vital capacity from total lung capacity determined by the single breath helium dilution (TLCsb) to measure CO diffusing capacity in 2,680 subjects (8 to 64 years old) of a general population sample. There were 712 normal subjects (243 male and 469 female subjects) selec...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.102.4.1209
更新日期:1992-10-01 00:00:00
abstract:CASE PRESENTATION:A 69-year-old man consulted for a 3-day history of fever, wet cough, and yellow-green phlegm. He denied having any dyspnea, chest pain, hemoptysis, swallowing disorders, choke, chills, asthenia, anorexia, or weight loss. He reported a continuous dry cough and three episodes of pneumonia in the past 4 ...
journal_title:Chest
pub_type:
doi:10.1016/j.chest.2020.07.033
更新日期:2020-12-01 00:00:00
abstract::COPD and OSA are both highly prevalent, which implies that both disorders occurring together (overlap syndrome) is likely to be common based on chance association alone. However, different clinical COPD phenotypes influence the likelihood of coexisting OSA in that the increased lung volumes and low BMI associated with...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1016/j.chest.2017.04.160
更新日期:2017-12-01 00:00:00
abstract:STUDY OBJECTIVES:Evaluation of the effectiveness of negative-pressure ventilation (NPV) with the use of the iron lung vs noninvasive positive-pressure ventilation (NIPPV) in the treatment of COPD patients with acute on chronic respiratory failure. DESIGN:A retrospective case-control study. SETTING:Four Italian respir...
journal_title:Chest
pub_type: 杂志文章,多中心研究
doi:10.1378/chest.121.1.189
更新日期:2002-01-01 00:00:00
abstract::Tracheal aspirates from four previously healthy infants with acute pulmonary hemorrhage, and small volume bronchial lavages from children undergoing flexible fiberoptic bronchoscopy were examined for pulmonary alveolar macrophages (PAM) containing hemosiderin. Hemosiderin formation was also studied in vitro. Macrophag...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.86.3.409
更新日期:1984-09-01 00:00:00
abstract::Pulmonary function studies were conducted one to two days prior to, two weeks after, and an average of 116 days after coronary artery revascularization surgery. Preoperation it was found that 11 of 19 patients had mild to moderate obstruction, 8 of 17 had diffusing capacity less than 80 percent of predicted, and 9 of ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.73.3.316
更新日期:1978-03-01 00:00:00
abstract::To assess the responsiveness of the cerebral vessels to chronic hypercapnia, we measured middle cerebral artery flow velocity by transcranial Doppler ultrasound in 20 normal subjects and in 14 COLD patients before and after stimulation by progressive hypercapnia (rebreathing test) or by intravenous administration of a...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.102.1.135
更新日期:1992-07-01 00:00:00
abstract:STUDY OBJECTIVE:To measure the ability of a set of clinical parameters, the Winthrop-University Hospital (WUH) criteria, to identify Legionella pneumonia while discriminating against bacteremic pneumococcal pneumonia at the time of hospitalization for community-acquired pneumonia (CAP). DESIGN:Retrospective case-contr...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.120.4.1064
更新日期:2001-10-01 00:00:00
abstract:BACKGROUND:Matrix metalloproteinase (MMP)-7 was reported to be a key molecule in the pathogenesis of idiopathic pulmonary fibrosis (IPF) based on the result of microarray analysis and knockout mice. However, the role of MMP-7 has not been determined in other types of idiopathic interstitial pneumonia (IIP). The aim of ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.07-2116
更新日期:2008-05-01 00:00:00
abstract::Exertional dyspnea is a common complaint for patients seen in pulmonary, cardiac, and general medicine clinics, and elucidating the cause is often challenging, particularly when physical examination, echocardiography, radiography, and pulmonary function test results are inconclusive. Invasive cardiopulmonary exercise ...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1016/j.chest.2020.05.552
更新日期:2020-11-01 00:00:00
abstract::To evaluate the efficacy of mask-mode digital subtraction angiography in selective coronary arteriography, we compared computer-based digital subtraction angiograms to standard film-based angiograms in 77 patients. Digital angiography was performed utilizing a 512(2) matrix and a framing rate of 30 frames/second. Radi...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.90.6.793
更新日期:1986-12-01 00:00:00
abstract:STUDY OBJECTIVE:Immune and inflammatory mechanisms could play a significant role in pulmonary arterial hypertension (PAH) genesis or progression, especially in patients with connective tissue diseases. Immunosuppressive therapy should be better evaluated in this setting. STUDY DESIGN:Monocentric retrospective study. ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.130.1.182
更新日期:2006-07-01 00:00:00
abstract:OBJECTIVE:An overdiagnosis bias occurs with the diagnosis of a disease that does not produce signs or symptoms before the patient dies from other causes. We sought to determine whether overdiagnosis bias is a factor when screening for squamous cell carcinoma of the lung. DESIGN:Retrospective study of the Miyagi Popula...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.126.1.108
更新日期:2004-07-01 00:00:00
abstract::We characterized the bronchopulmonary distribution of a 0.9 percent saline aerosol (1.12 microM) labelled with 99mTc sulfur colloid in nine normal subjects and five patients with CF. Homogeneity of distribution was quantified using indices derived from computerized analysis of Anger camera pulmonary images including s...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.95.4.822
更新日期:1989-04-01 00:00:00
abstract:STUDY OBJECTIVES:We set out to determine whether there is a difference in postoperative pain and recovery after the patient undergoes the axillary muscle-sparing incision (ie, muscle-sparing thoracotomy [MT]) vs the modified posterolateral incision (ie, posterolateral thoracotomy [PT]). DESIGN:Analysis of a database o...
journal_title:Chest
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1378/chest.128.4.2664
更新日期:2005-10-01 00:00:00
abstract:STUDY OBJECTIVES:The aim of this study was to evaluate the immediate and midterm results of coronary artery bypass grafting with the radial artery (RA) as a conduit. PATIENTS:Two hundred forty-one patients underwent myocardial revascularization using the RA. In 78.5% of patients, three coronary vessels were involved, ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.122.6.2075
更新日期:2002-12-01 00:00:00
abstract::It has been suggested that spirometry should be incorporated into the routine examination of every patient, analogous to obtaining vital signs. To determine the impact of spirometry on the management of outpatients with respiratory disease, spirometry was performed on 150 consecutive patients (123 men and 27 women, me...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.99.3.730
更新日期:1991-03-01 00:00:00
abstract::Relationships were investigated between chronic bronchitis and plant dust exposure assessed by quantification of barn threshing and cattle foddering and chronic bronchitis and acute respiratory syndromes after plant mold dust exposure. Two groups of male dairy farmers were studied in the Doubs region, France: 197 with...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.103.2.417
更新日期:1993-02-01 00:00:00
abstract::This study evaluated the influence of pregnancy as a relapse factor in pulmonary tuberculosis in 215 patients who recieved adequate chemotherapy. A comparison was made between the evolution of patients who had pregnancies and those who did not. On ending the period of observation (details are lacking with respect to o...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.68.6.800
更新日期:1975-12-01 00:00:00
abstract::Propofol, a new intravenous sedative agent, was investigated in 41 asthmatic patients undergoing day-case (outpatient) fiberoptic bronchoscopy. The study design was a randomized comparison between propofol and midazolam, which is a well-established intravenous sedative agent. The age, weight, and American Society of A...
journal_title:Chest
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1378/chest.104.4.1029
更新日期:1993-10-01 00:00:00
abstract::A 26-year-old woman presented with abnormal findings on a chest radiograph. She had no significant history other than a fever 4 months prior to presentation that had resolved without a definite cause identified. She denied cough, shortness of breath, chest pain, history of smoking, environmental exposures, or prior pr...
journal_title:Chest
pub_type: 杂志文章
doi:10.1016/j.chest.2015.08.023
更新日期:2016-03-01 00:00:00
abstract:CASE PRESENTATION:An 84-year-old man without a history of smoking presented with progressive dyspnea of 6 months' duration accompanied by fatigue and unintentional weight loss. He denied fever, chills, chest pain, hemoptysis, rash, joint pains, or muscle aches. He had multiple hospitalizations for similar presentations...
journal_title:Chest
pub_type: 杂志文章
doi:10.1016/j.chest.2017.03.013
更新日期:2017-08-01 00:00:00