Snoring, nocturnal hypoxemia, and the effect of oxygen inhalation.

Abstract:

:Men who snore heavily have an increased incidence of hypertension, angina, stroke, and neuropsychologic dysfunction, which may be due to nocturnal oxygen desaturation. Nocturnal oxygen therapy might be beneficial to such individuals by improving oxygenation and relieving tissue hypoxia. Twenty-eight asymptomatic heavy snoring men were recruited for polysomnographic monitoring during sleep. During the first half-night, air was breathed through a nasal cannula, and during the latter half-night, 2 L/min oxygen was administered. Breathing air, 20 subjects demonstrated sleep apneas, hypopneas and nocturnal oxygen desaturation. Eighteen subjects had more than ten apneas plus hypopneas per hour. Thirteen subjects reached low oxygen saturation below 80 percent and eight below 70 percent. Only 13 of the 20 subjects showed improvement with oxygen therapy. Apneas alone were not decreased in frequency and were lengthened with oxygen therapy. Episodes of oxygen desaturation were improved by oxygen therapy and consequently, rates of hypopnea were decreased. Severe sleep apnea, hypopnea and oxygen desaturation are common in asymptomatic male snorers, and oxygen therapy is not always beneficial.

journal_name

Chest

journal_title

Chest

authors

Block AJ,Hellard DW,Cicale MJ

doi

10.1378/chest.92.3.411

subject

Has Abstract

pub_date

1987-09-01 00:00:00

pages

411-7

issue

3

eissn

0012-3692

issn

1931-3543

pii

S0012-3692(15)43532-9

journal_volume

92

pub_type

杂志文章

相关文献

CHEST文献大全
  • Detection of intrapulmonary shunts in schistosomal cor pulmonale.

    abstract::Two patients with schistosomal cor pulmonale and central cyanosis were studied by contrast-enhanced echocardiography, using indocyanine green injection. Intrapulmonary shunts were detected by this method. To our knowledge, this is the first report that proves the presence of intrapulmonary shunts in schistosomal cor p...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.104.4.1280

    authors: Rafla SM,Sourour S

    更新日期:1993-10-01 00:00:00

  • A randomized trial of two types of nurse-assisted home care for patients with COPD.

    abstract:STUDY OBJECTIVES:Whereas pulmonary rehabilitation reduces symptoms and improves the quality of life of patients with COPD and is recommended in management guidelines, few patients have access to rehabilitation services. The purpose of this study was to investigate the effectiveness of increasing access to selected comp...

    journal_title:Chest

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1378/chest.128.4.2017

    authors: Coultas D,Frederick J,Barnett B,Singh G,Wludyka P

    更新日期:2005-10-01 00:00:00

  • Cysteinyl leukotrienes in allergic inflammation: strategic target for therapy.

    abstract::Systemically bioavailable leukotriene receptor antagonists (LTRAs) can reduce the essential components of allergic inflammation in allergic rhinitis (AR) and asthma by blocking cysteinyl leukotriene (CysLT) activity, resulting in a wide range of clinical effects. CysLTs, mediators, and modulators in the pathophysiolog...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.127.4.1312

    authors: Busse W,Kraft M

    更新日期:2005-04-01 00:00:00

  • Patient and Family Engagement in Designing and Implementing a Weaning Trial: A Novel Research Paradigm in Critical Care.

    abstract::The call for meaningful patient and family engagement in research has recently gained considerable momentum. This article defines patient and family engagement broadly and specifically in clinical research. Using a multicenter, North American weaning trial as an exemplar, we describe our early experiences as clinical ...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1016/j.chest.2017.06.028

    authors: Burns KEA,Devlin JW,Hill NS

    更新日期:2017-10-01 00:00:00

  • Esophageal-directed pressure support ventilation in normal volunteers.

    abstract:STUDY OBJECTIVES:To ascertain whether inspiratory pressure support (IPS) can be triggered reliably from and targeted at esophageal pressures (Pes), and to compare the work of breathing and time delay to initiation of inspiratory flow between conventional pressure support and esophageal-directed pressure support (EDPS)....

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.115.2.482

    authors: Barnard M,Shukla A,Lovell T,Goldstone J

    更新日期:1999-02-01 00:00:00

  • Endobronchial tuberculosis simulating lung cancer.

    abstract::Endobronchial tuberculosis, while relatively common before the advent of effective antituberculosis chemotherapy, is seldom recognized now. Four patients with what appeared to be primary tuberculosis complicated by endobronchial spread were recently seen by us. Three of the four patients presented with anterior segmen...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.86.4.642

    authors: Matthews JI,Matarese SL,Carpenter JL

    更新日期:1984-10-01 00:00:00

  • Effect of thoracentesis on respiratory mechanics and gas exchange in the patient receiving mechanical ventilation.

    abstract:BACKGROUND:This study reports the effect of thoracentesis on respiratory mechanics and gas exchange in patients receiving mechanical ventilation. STUDY DESIGN:Prospective. SETTING:University hospital. PATIENTS:Eight patient receiving mechanical ventilation with unilateral (n = 7) or bilateral (n = 1) large pleural e...

    journal_title:Chest

    pub_type: 临床试验,杂志文章

    doi:10.1378/chest.130.5.1354

    authors: Doelken P,Abreu R,Sahn SA,Mayo PH

    更新日期:2006-11-01 00:00:00

  • Successful treatment of right ventricular failure with atrial septostomy.

    abstract::In the case reported, a patient with severe right ventricular failure following coronary revascularization was successfully weaned from cardiopulmonary bypass following creation of an atrial septal defect. This technique facilitated rapid decompression of the failing right ventricle by shunting blood to the more compl...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.92.5.950

    authors: Swanson MJ,Fabaz AG,Jung JY

    更新日期:1987-11-01 00:00:00

  • Residual volume in a general population. Effects of body size, age, cigarette smoking, and respiratory symptoms.

    abstract::Residual volume (RV) was obtained by subtracting vital capacity from total lung capacity determined by the single breath helium dilution (TLCsb) to measure CO diffusing capacity in 2,680 subjects (8 to 64 years old) of a general population sample. There were 712 normal subjects (243 male and 469 female subjects) selec...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.102.4.1209

    authors: Paoletti P,Viegi G,Carrozzi L,Di Pede F,Modena P,Ballerin L,Baldacci S,Pedreschi M,Pistelli G,Giuntini C

    更新日期:1992-10-01 00:00:00

  • A 69-Year-Old Man With Chronic Cough and Recurrent Pneumonia.

    abstract:CASE PRESENTATION:A 69-year-old man consulted for a 3-day history of fever, wet cough, and yellow-green phlegm. He denied having any dyspnea, chest pain, hemoptysis, swallowing disorders, choke, chills, asthenia, anorexia, or weight loss. He reported a continuous dry cough and three episodes of pneumonia in the past 4 ...

    journal_title:Chest

    pub_type:

    doi:10.1016/j.chest.2020.07.033

    authors: Hoan L,Hang LM,Thanh Hong DT,Nhu Quynh NT,Linh LT,Cuong NN,Minh TN,Luan DT,Thang ND,Delphine N

    更新日期:2020-12-01 00:00:00

  • COPD-OSA Overlap Syndrome: Evolving Evidence Regarding Epidemiology, Clinical Consequences, and Management.

    abstract::COPD and OSA are both highly prevalent, which implies that both disorders occurring together (overlap syndrome) is likely to be common based on chance association alone. However, different clinical COPD phenotypes influence the likelihood of coexisting OSA in that the increased lung volumes and low BMI associated with...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1016/j.chest.2017.04.160

    authors: McNicholas WT

    更新日期:2017-12-01 00:00:00

  • Iron lung vs mask ventilation in the treatment of acute on chronic respiratory failure in COPD patients: a multicenter study.

    abstract:STUDY OBJECTIVES:Evaluation of the effectiveness of negative-pressure ventilation (NPV) with the use of the iron lung vs noninvasive positive-pressure ventilation (NIPPV) in the treatment of COPD patients with acute on chronic respiratory failure. DESIGN:A retrospective case-control study. SETTING:Four Italian respir...

    journal_title:Chest

    pub_type: 杂志文章,多中心研究

    doi:10.1378/chest.121.1.189

    authors: Corrado A,Confalonieri M,Marchese S,Mollica C,Villella G,Gorini M,Della Porta R

    更新日期:2002-01-01 00:00:00

  • Time course of hemosiderin production and clearance by human pulmonary macrophages.

    abstract::Tracheal aspirates from four previously healthy infants with acute pulmonary hemorrhage, and small volume bronchial lavages from children undergoing flexible fiberoptic bronchoscopy were examined for pulmonary alveolar macrophages (PAM) containing hemosiderin. Hemosiderin formation was also studied in vitro. Macrophag...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.86.3.409

    authors: Sherman JM,Winnie G,Thomassen MJ,Abdul-Karim FW,Boat TF

    更新日期:1984-09-01 00:00:00

  • Pre- and postoperative pulmonary function abnormalities in coronary artery revascularization surgery.

    abstract::Pulmonary function studies were conducted one to two days prior to, two weeks after, and an average of 116 days after coronary artery revascularization surgery. Preoperation it was found that 11 of 19 patients had mild to moderate obstruction, 8 of 17 had diffusing capacity less than 80 percent of predicted, and 9 of ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.73.3.316

    authors: Braun SR,Birnbaum ML,Chopra PS

    更新日期:1978-03-01 00:00:00

  • Cerebral vascular responsiveness in chronic hypercapnia.

    abstract::To assess the responsiveness of the cerebral vessels to chronic hypercapnia, we measured middle cerebral artery flow velocity by transcranial Doppler ultrasound in 20 normal subjects and in 14 COLD patients before and after stimulation by progressive hypercapnia (rebreathing test) or by intravenous administration of a...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.102.1.135

    authors: Clivati A,Ciofetti M,Cavestri R,Longhini E

    更新日期:1992-07-01 00:00:00

  • Evaluation of the Winthrop-University Hospital criteria to identify Legionella pneumonia.

    abstract:STUDY OBJECTIVE:To measure the ability of a set of clinical parameters, the Winthrop-University Hospital (WUH) criteria, to identify Legionella pneumonia while discriminating against bacteremic pneumococcal pneumonia at the time of hospitalization for community-acquired pneumonia (CAP). DESIGN:Retrospective case-contr...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.120.4.1064

    authors: Gupta SK,Imperiale TF,Sarosi GA

    更新日期:2001-10-01 00:00:00

  • Is metalloproteinase-7 specific for idiopathic pulmonary fibrosis?

    abstract:BACKGROUND:Matrix metalloproteinase (MMP)-7 was reported to be a key molecule in the pathogenesis of idiopathic pulmonary fibrosis (IPF) based on the result of microarray analysis and knockout mice. However, the role of MMP-7 has not been determined in other types of idiopathic interstitial pneumonia (IIP). The aim of ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.07-2116

    authors: Huh JW,Kim DS,Oh YM,Shim TS,Lim CM,Lee SD,Koh Y,Kim WS,Kim WD,Kim KR

    更新日期:2008-05-01 00:00:00

  • Performance and Interpretation of Invasive Hemodynamic Exercise Testing.

    abstract::Exertional dyspnea is a common complaint for patients seen in pulmonary, cardiac, and general medicine clinics, and elucidating the cause is often challenging, particularly when physical examination, echocardiography, radiography, and pulmonary function test results are inconclusive. Invasive cardiopulmonary exercise ...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1016/j.chest.2020.05.552

    authors: Jain CC,Borlaug BA

    更新日期:2020-11-01 00:00:00

  • Diagnostic accuracy of coronary angiography utilizing computer-based digital subtraction methods. Comparison to conventional cineangiography.

    abstract::To evaluate the efficacy of mask-mode digital subtraction angiography in selective coronary arteriography, we compared computer-based digital subtraction angiograms to standard film-based angiograms in 77 patients. Digital angiography was performed utilizing a 512(2) matrix and a framing rate of 30 frames/second. Radi...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.90.6.793

    authors: Goldberg HL,Moses JW,Fisher J,Tamari I,Borer JS

    更新日期:1986-12-01 00:00:00

  • Immunosuppressive therapy in connective tissue diseases-associated pulmonary arterial hypertension.

    abstract:STUDY OBJECTIVE:Immune and inflammatory mechanisms could play a significant role in pulmonary arterial hypertension (PAH) genesis or progression, especially in patients with connective tissue diseases. Immunosuppressive therapy should be better evaluated in this setting. STUDY DESIGN:Monocentric retrospective study. ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.130.1.182

    authors: Sanchez O,Sitbon O,Jaïs X,Simonneau G,Humbert M

    更新日期:2006-07-01 00:00:00

  • The natural history of radiographically occult bronchogenic squamous cell carcinoma: a retrospective study of overdiagnosis bias.

    abstract:OBJECTIVE:An overdiagnosis bias occurs with the diagnosis of a disease that does not produce signs or symptoms before the patient dies from other causes. We sought to determine whether overdiagnosis bias is a factor when screening for squamous cell carcinoma of the lung. DESIGN:Retrospective study of the Miyagi Popula...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.126.1.108

    authors: Sato M,Saito Y,Endo C,Sakurada A,Feller-Kopman D,Ernst A,Kondo T

    更新日期:2004-07-01 00:00:00

  • Homogeneity of bronchopulmonary distribution of 99mTc aerosol in normal subjects and in cystic fibrosis patients.

    abstract::We characterized the bronchopulmonary distribution of a 0.9 percent saline aerosol (1.12 microM) labelled with 99mTc sulfur colloid in nine normal subjects and five patients with CF. Homogeneity of distribution was quantified using indices derived from computerized analysis of Anger camera pulmonary images including s...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.95.4.822

    authors: Laube BL,Links JM,LaFrance ND,Wagner HN Jr,Rosenstein BJ

    更新日期:1989-04-01 00:00:00

  • Pain and physical function are similar following axillary, muscle-sparing vs posterolateral thoracotomy.

    abstract:STUDY OBJECTIVES:We set out to determine whether there is a difference in postoperative pain and recovery after the patient undergoes the axillary muscle-sparing incision (ie, muscle-sparing thoracotomy [MT]) vs the modified posterolateral incision (ie, posterolateral thoracotomy [PT]). DESIGN:Analysis of a database o...

    journal_title:Chest

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1378/chest.128.4.2664

    authors: Ochroch EA,Gottschalk A,Augoustides JG,Aukburg SJ,Kaiser LR,Shrager JB

    更新日期:2005-10-01 00:00:00

  • Midterm clinical results in myocardial revascularization using the radial artery.

    abstract:STUDY OBJECTIVES:The aim of this study was to evaluate the immediate and midterm results of coronary artery bypass grafting with the radial artery (RA) as a conduit. PATIENTS:Two hundred forty-one patients underwent myocardial revascularization using the RA. In 78.5% of patients, three coronary vessels were involved, ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.122.6.2075

    authors: Beghi C,Nicolini F,Budillon AM,Borrello B,Ballore L,Reverberi C,Gherli T

    更新日期:2002-12-01 00:00:00

  • Indications for spirometry in outpatients with respiratory disease.

    abstract::It has been suggested that spirometry should be incorporated into the routine examination of every patient, analogous to obtaining vital signs. To determine the impact of spirometry on the management of outpatients with respiratory disease, spirometry was performed on 150 consecutive patients (123 men and 27 women, me...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.99.3.730

    authors: Owens MW,Anderson WM,George RB

    更新日期:1991-03-01 00:00:00

  • Etiologic factors of chronic bronchitis in dairy farmers. Case control study in the Doubs region of France.

    abstract::Relationships were investigated between chronic bronchitis and plant dust exposure assessed by quantification of barn threshing and cattle foddering and chronic bronchitis and acute respiratory syndromes after plant mold dust exposure. Two groups of male dairy farmers were studied in the Doubs region, France: 197 with...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.103.2.417

    authors: Dalphin JC,Pernet D,Dubiez A,Debieuvre D,Allemand H,Depierre A

    更新日期:1993-02-01 00:00:00

  • Tuberculosis and pregnancy. Five- to ten-year review of 215 patients in their fertile age.

    abstract::This study evaluated the influence of pregnancy as a relapse factor in pulmonary tuberculosis in 215 patients who recieved adequate chemotherapy. A comparison was made between the evolution of patients who had pregnancies and those who did not. On ending the period of observation (details are lacking with respect to o...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.68.6.800

    authors: de March A P

    更新日期:1975-12-01 00:00:00

  • A comparative evaluation of propofol and midazolam as sedative agents in fiberoptic bronchoscopy.

    abstract::Propofol, a new intravenous sedative agent, was investigated in 41 asthmatic patients undergoing day-case (outpatient) fiberoptic bronchoscopy. The study design was a randomized comparison between propofol and midazolam, which is a well-established intravenous sedative agent. The age, weight, and American Society of A...

    journal_title:Chest

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1378/chest.104.4.1029

    authors: Clarkson K,Power CK,O'Connell F,Pathmakanthan S,Burke CM

    更新日期:1993-10-01 00:00:00

  • A 26-Year-Old Woman With a Small Right Lung and a Right-Sided Heart.

    abstract::A 26-year-old woman presented with abnormal findings on a chest radiograph. She had no significant history other than a fever 4 months prior to presentation that had resolved without a definite cause identified. She denied cough, shortness of breath, chest pain, history of smoking, environmental exposures, or prior pr...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1016/j.chest.2015.08.023

    authors: Albores J,Smith MI

    更新日期:2016-03-01 00:00:00

  • An 84-Year-Old Man With Progressive Dyspnea and an Abnormal Chest CT Scan.

    abstract:CASE PRESENTATION:An 84-year-old man without a history of smoking presented with progressive dyspnea of 6 months' duration accompanied by fatigue and unintentional weight loss. He denied fever, chills, chest pain, hemoptysis, rash, joint pains, or muscle aches. He had multiple hospitalizations for similar presentations...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1016/j.chest.2017.03.013

    authors: Fakih HAM,Samra Y,Ataya A,Prasad A,Papierniak E,Wakefield D,Urbine D

    更新日期:2017-08-01 00:00:00