Cerebral vascular responsiveness in chronic hypercapnia.

Abstract:

:To assess the responsiveness of the cerebral vessels to chronic hypercapnia, we measured middle cerebral artery flow velocity by transcranial Doppler ultrasound in 20 normal subjects and in 14 COLD patients before and after stimulation by progressive hypercapnia (rebreathing test) or by intravenous administration of an acetazolamide bolus. The results showed no statistically significant difference in baseline flow velocity between the normal subjects and the COLD patients. The COLD patients showed a reduced cerebral vascular responsiveness to both stimuli. Cerebral blood flow is normal in chronic hypercapnia and the mechanism by which compensation is achieved leads to a decrease in cerebral vascular responsiveness.

journal_name

Chest

journal_title

Chest

authors

Clivati A,Ciofetti M,Cavestri R,Longhini E

doi

10.1378/chest.102.1.135

subject

Has Abstract

pub_date

1992-07-01 00:00:00

pages

135-8

issue

1

eissn

0012-3692

issn

1931-3543

pii

S0012-3692(16)35857-3

journal_volume

102

pub_type

杂志文章

相关文献

CHEST文献大全
  • Pulmonary hemorrhage. An uncommon cause of pulmonary infiltrates in patients with AIDS.

    abstract::We describe two patients with AIDS who developed new diffuse pulmonary infiltrates during the course of their hospitalization. In both cases, the infiltrates were attributed to pulmonary hemorrhage complicating an existing condition rather than representing a new pulmonary process. Identification of pulmonary hemorrha...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.106.6.1891

    authors: Koziel H,Haley K,Nasser I,Filderman AE

    更新日期:1994-12-01 00:00:00

  • Immediate operative treatment for massive hemoptysis.

    abstract::A series of 15 patients with life threatening, massive hemoptysis is reported. Thirteen of these patients underwent immediate operative treatment with only three deaths. One died after bronchoscopic identification of the bleeding site while awaiting elective thoracotomy. The other patient left the hospital against med...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.67.2.152

    authors: McCollun WB,Mattox KL,Guinn GA,Beall AC Jr

    更新日期:1975-02-01 00:00:00

  • Diagnosis of superior vena caval obstruction by transesophageal echocardiography.

    abstract::Superior vena caval (SVC) syndrome may be caused by extravascular compression or intravascular obstruction. Knowing the mechanism of SVC syndrome enables the physician to choose appropriate treatment. Transesophageal echocardiography (TEE) is a safe bedside procedure that is excellent for evaluating the SVC and its su...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.101.3.874

    authors: Ayala K,Chandrasekaran K,Karalis DG,Parris TM,Ross JJ Jr

    更新日期:1992-03-01 00:00:00

  • Bilateral tuberculous pleural effusions with markedly different characteristics.

    abstract::A 72-year-old man presented with malaise, weight loss, and cough. Chest radiograph revealed bilateral pleural effusions. On thoracentesis, the left effusion was a clear yellow exudate with more than 90% lymphocytes, and the right effusion was a grossly bloody exudate with more than 90% neutrophils. Cultures of both ef...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.110.3.849

    authors: Murin S,Moritz E

    更新日期:1996-09-01 00:00:00

  • Fortuitous esophageal intubation.

    abstract::Esophageal malposition is a potentially disastrous complication of attempted airway intubation. We report an unusual case in which a promptly recognized esophageal intubation aided detection of a perforated gastric ulcer. After the endotracheal tube was repositioned and the ulcer was surgically repaired, our patient h...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.103.2.625

    authors: Dunham D,Schmidt GA

    更新日期:1993-02-01 00:00:00

  • Patients With Fibrotic Interstitial Lung Disease Hospitalized for Acute Respiratory Worsening: A Large Cohort Analysis.

    abstract:BACKGROUND:Acute respiratory worsening (ARW) requiring hospitalization in patients with fibrotic interstitial lung disease (f-ILD) is common. Little is known about the frequency and implications of ARW in IPF and non-IPF ILD patients hospitalized for acute exacerbation (AE) vs known causes of ARW. METHODS:All consecut...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1016/j.chest.2015.12.026

    authors: Moua T,Westerly BD,Dulohery MM,Daniels CE,Ryu JH,Lim KG

    更新日期:2016-05-01 00:00:00

  • The treatment of pleuropulmonary amebiasis with metronidazole.

    abstract::One hundred forty patients with pleuropulmonary amebiasis were classified radiographically in order to rationalize therapy based on the use of metronidazole. Amebic testing with gel diffusion, serial chest x-ray films, and observation of the patient's response to treatment have dominated management of the patients, 13...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.73.5.647

    authors: Cameron EW

    更新日期:1978-05-01 00:00:00

  • Predictors of time to death after terminal withdrawal of mechanical ventilation in the ICU.

    abstract:BACKGROUND:Little information exists about the expected time to death after terminal withdrawal of mechanical ventilation. We sought to determine the independent predictors of time to death after withdrawal of mechanical ventilation. METHODS:We conducted a secondary analysis from a cluster randomized trial of an end-o...

    journal_title:Chest

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1378/chest.10-0289

    authors: Cooke CR,Hotchkin DL,Engelberg RA,Rubinson L,Curtis JR

    更新日期:2010-08-01 00:00:00

  • Acute diverticulitis following cardiac surgery.

    abstract::Gastrointestinal complications requiring surgical correction following cardiopulmonary bypass most frequently involve the upper gastrointestinal tract. Surgical diseases of the colon are quite unusual in this setting. We recently performed cardiac surgery on three patients who developed acute diverticulitis requiring ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.89.5.756

    authors: Burton NA,Albus RA,Graeber GM,Lough FC

    更新日期:1986-05-01 00:00:00

  • Association between right ventricular function and perfusion abnormalities in hemodynamically stable patients with acute pulmonary embolism.

    abstract:BACKGROUND/OBJECTIVES:Patients presenting with acute pulmonary embolism associated with hemodynamic compromise exhibit right ventricular enlargement and dysfunction on transthoracic echocardiogram. However, the degree of echocardiographic abnormalities among hemodynamically stable patients without preexisting cardiopul...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.113.3.665

    authors: Miller RL,Das S,Anandarangam T,Leibowitz DW,Alderson PO,Thomashow B,Homma S

    更新日期:1998-03-01 00:00:00

  • Radionuclide scintiphotography in defining postoperative pulmonary vasoconstriction. Succesful results after tolazoline administration in a four-month-old infant with congenital heart disease.

    abstract::99mTechnetium macroaggregated albumin has successfully been used to define severe postoperative pulmonary vasoconstriction in a four-month-old boy with D-transposition of the great vessels who had undergone a Blalock-Hanlon surgical atrial septectomy. Radionuclide imaging documented clinically suspected pulmonary vaso...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.76.3.274

    authors: Moodie DS,Levy JM,Kahn DR,Lieberman LM,Pastakia B

    更新日期:1979-09-01 00:00:00

  • Daytime sleepiness in patients with congestive heart failure and Cheyne-Stokes respiration.

    abstract:STUDY OBJECTIVE:To determine whether patients with congestive heart failure who develop Cheyne-Stokes respiration (CSR) during sleep experience excessive daytime sleepiness. This was addressed by comparing sleep quality and daytime sleepiness in three groups: patients with CHF and CSR during sleep (CSR group), patients...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.107.4.952

    authors: Hanly P,Zuberi-Khokhar N

    更新日期:1995-04-01 00:00:00

  • Delayed perforation of the esophagus by a closed thoracostomy tube.

    abstract::We report on a previously undocumented complication of a trocar-free thoracostomy tube--delayed perforation of a normal esophagus. The complication presented clinically with fever and copious enteric drainage four days after thoracostomy tube insertion. Diagnosis was established by a contrast study of the esophagus. R...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.104.6.1897

    authors: Shapira OM,Aldea GS,Kupferschmid J,Shemin RJ

    更新日期:1993-12-01 00:00:00

  • Antithrombotic therapy in atrial fibrillation: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy.

    abstract::This chapter about antithrombotic therapy in atrial fibrillation (AF) is part of the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy: Evidence Based Guidelines. Grade 1 recommendations are strong and indicate that the benefits do, or do not, outweigh risks, burden, and costs. Grade 2 suggests that i...

    journal_title:Chest

    pub_type: 指南,杂志文章,实务指引,评审

    doi:10.1378/chest.126.3_suppl.429S

    authors: Singer DE,Albers GW,Dalen JE,Go AS,Halperin JL,Manning WJ

    更新日期:2004-09-01 00:00:00

  • Radiographic fibrosis score predicts survival in hypersensitivity pneumonitis.

    abstract:BACKGROUND:It is unknown if the radiographic fibrosis score predicts mortality in persistent hypersensitivity pneumonitis (HP) and if survival is similar to that observed in idiopathic pulmonary fibrosis (IPF) when adjusting for the extent of radiographic fibrosis. METHODS:We reviewed records from 177 patients with HP...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.12-2623

    authors: Mooney JJ,Elicker BM,Urbania TH,Agarwal MR,Ryerson CJ,Nguyen MLT,Woodruff PG,Jones KD,Collard HR,King TE Jr,Koth LL

    更新日期:2013-08-01 00:00:00

  • Pulmonary hypertension in chronic obstructive pulmonary disease. Multivariate analysis.

    abstract::The severity of pulmonary hypertension was evaluated by right cardiac catheterization in 89 patients with stable chronic obstructive pulmonary disease, both at rest and during maximum treadmill exercise. Thirty-one patients were found to have pulmonary hypertension at rest, defined as a mean pulmonary arterial pressur...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.90.2.185

    authors: Keller CA,Shepard JW Jr,Chun DS,Vasquez P,Dolan GF

    更新日期:1986-08-01 00:00:00

  • The lung in immunoblastic lymphadenopathy.

    abstract::Immunoblastic lymphadenopathy presents with fever, malaise, cough, dyspnea, lymphadenopathy, hepatosplenomegaly, hypergammaglobulinemia, interstitial pulmonary infiltrates, mediastinal adenopathy, and effusions. The diagnosis is made on the basis of lymph node biopsy. Based on the course in our patients and the cases ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.80.3.312

    authors: Bradley SL,Dines DE,Banks PM,Hill RW

    更新日期:1981-09-01 00:00:00

  • Repeatability of inspiratory capacity during incremental exercise in patients with severe COPD.

    abstract:STUDY OBJECTIVE:Estimating lung volume using inspiratory capacity (IC) maneuvers is a useful way of tracking dynamic hyperinflation. An understanding of the repeatability of the IC in a clinical setting is important when evaluating an individual's response to a therapeutic intervention that might influence lung volume....

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.121.3.708

    authors: Dolmage TE,Goldstein RS

    更新日期:2002-03-01 00:00:00

  • Quantification of traumatic hemomediastinum using transesophageal echocardiography: impact on patient management.

    abstract:STUDY OBJECTIVES:To determine whether the quantitative evaluation of hemomediastinum using transesophageal echocardiography (TEE) is predictive of the presence of a traumatic disruption of the thoracic aorta (TDA) or its branches in patients who have sustained severe blunt chest trauma. DESIGN:Retrospective study. SE...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.113.6.1475

    authors: Vignon P,Rambaud G,François B,Preux PM,Lang RM,Gastinne H

    更新日期:1998-06-01 00:00:00

  • Correlation of leukocyte esterase detection by reagent strips and the presence of neutrophils: a study in BAL fluid.

    abstract:STUDY OBJECTIVE:In the present study, we evaluated the leukocyte esterase (LE) area of a reagent strip designed for urinalysis for the semiquantitative measurement of the percentage of polymorphonuclear neutrophils (PMNs) in BAL fluid. DESIGN:Prospective. The relative PMN counts (obtained by conventional microscopy an...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.118.5.1450

    authors: Jacobs JA,De Brauwer EI,Cornelissen EI,Drent M

    更新日期:2000-11-01 00:00:00

  • Nocturnal nasal continuous positive airway pressure in patients with chronic obstructive pulmonary disease. Influence on waking respiratory muscle function.

    abstract::Patients with COPD often have reduced inspiratory muscle strength and endurance as well as poor exercise tolerance. Increased inspiratory work during sleep (probably due to increased upper airway resistance) may further strain these compromised respiratory muscles in COPD patients. We hypothesized that nasal continuou...

    journal_title:Chest

    pub_type: 临床试验,杂志文章

    doi:10.1378/chest.106.4.1100

    authors: Mezzanotte WS,Tangel DJ,Fox AM,Ballard RD,White DP

    更新日期:1994-10-01 00:00:00

  • Pulmonary lymphangioleiomyomatosis and cerebrotendinous xanthomatosis: is there a link?

    abstract::A 41-year-old woman had progressive shortness of breath. Cerebrotendinous xanthomatosis was diagnosed 4 years before. An open-lung biopsy showed the simultaneous presence of cerebrotendinous xanthomatosis and pulmonary lymphangioleiomyomatosis. This is perhaps the first time the coincidental occurrence of these two di...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.112.1.273

    authors: Dormans TP,Verrips A,Bulten J,Cox N

    更新日期:1997-07-01 00:00:00

  • Lung MRI as a possible alternative to CT scan for patients with primary immune deficiencies and increased radiosensitivity.

    abstract:BACKGROUND:Patients with common variable immunodeficiency (CVID) suffer from respiratory infections leading over time to permanent lung damage. Increased radiosensitivity has been described, and clinicians should consider a risk-benefit assessment when ordering a CT scan, in that the exact level of "safe" radiation exp...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.10-3147

    authors: Serra G,Milito C,Mitrevski M,Granata G,Martini H,Pesce AM,Sfika I,Bonanni L,Catalano C,Fraioli F,Quinti I

    更新日期:2011-12-01 00:00:00

  • Multicentric endobronchial granular cell myoblastoma.

    abstract::Granular cell myoblastoma (GCM) is a rare benign neoplasm involving the tracheobronchial tree. It is believed to arise from the Schwann cell. Four cases of tracheobronchial GCM, all of which were multicentric, are presented and a conservative therapeutic approach is suggested. ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.98.4.945

    authors: Redjaee B,Rohatgi PK,Herman MA

    更新日期:1990-10-01 00:00:00

  • Noninvasive positive pressure ventilation: successful outcome in patients with acute lung injury/ARDS.

    abstract:BACKGROUND:There is increasing support for the use of noninvasive positive pressure ventilation (NPPV) in the treatment of patients with acute respiratory failure. Highest success rates are recorded in patients with exacerbation of COPD, particularly in patients presenting primarily with hypercarbic respiratory failure...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.115.1.173

    authors: Rocker GM,Mackenzie MG,Williams B,Logan PM

    更新日期:1999-01-01 00:00:00

  • Disseminated histoplasmosis followed by disseminated coccidioidomycosis.

    abstract::A case of disseminated histoplasmosis followed later by disseminated coccidioidomycosis is described. The clinical illness and immunologic studies suggest subtle defects that may have existed antecedent to infection and, thus, provided an opportunity for widespread dissemination by these normally nonopportunistic orga...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.72.2.238

    authors: Kaplan P,Graybill JR,Thor D

    更新日期:1977-08-01 00:00:00

  • Idiopathic pulmonary hypertension associated with nodular pulmonary infiltrates and portal venous thrombosis.

    abstract::A case of idiopathic pulmonary hypertension is associated with portal venous thrombosis. The patient's chest roentgenogram revealed numerous nodular densities which at necropsy were found to have been caused by an exuberant fibroblastic reaction around small pulmonary arterioles. This is an example of the unusual asso...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.78.1.111

    authors: Bower JS,Dantzker DR,Naylor B

    更新日期:1980-07-01 00:00:00

  • The effects of cocaine and heroin use on intubation rates and hospital utilization in patients with acute asthma exacerbations.

    abstract:BACKGROUND:The use of both heroin and cocaine has been associated with asthma exacerbations. However, the magnitude of this effect has not been adequately described. The purpose of this study was to examine the association between cocaine or heroin use and asthma severity. METHODS:We conducted a retrospective chart re...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.128.4.1951

    authors: Levine M,Iliescu ME,Margellos-Anast H,Estarziau M,Ansell DA

    更新日期:2005-10-01 00:00:00

  • Mitral valve replacement: a comparison of two prostheses.

    abstract::Between November, 1965 and June, 1970, 175 patients underwent mitral valve replacement with the Smeloff-Cutter prosthesis (109 patients) or the toroidal valve (66 patients). The early mortality for patients with a toroidal mitral prosthesis was 18.2 percent (12 patients) and the late mortality 34.8 percent (23 patient...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.71.2.135

    authors: Rees JR,Holswade GR,Carlson RG,Subramanian VA,Murphy TE,Lillehei CW

    更新日期:1977-02-01 00:00:00

  • Usual interstitial pneumonia associated with primary Sjögren's syndrome.

    abstract::We describe the first case, to our knowledge, of usual interstitial pneumonia (UIP) as the pulmonary manifestation in primary Sjögren's syndrome (SjS). A 45-year-old woman was admitted to our hospital because of a dry cough and an interstitial shadow on a chest roentgenogram. Labial biopsy and sialogram confirmed a di...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.108.6.1756

    authors: Kadota J,Kusano S,Kawakami K,Morikawa T,Kohno S

    更新日期:1995-12-01 00:00:00