Usual interstitial pneumonia associated with primary Sjögren's syndrome.

Abstract:

:We describe the first case, to our knowledge, of usual interstitial pneumonia (UIP) as the pulmonary manifestation in primary Sjögren's syndrome (SjS). A 45-year-old woman was admitted to our hospital because of a dry cough and an interstitial shadow on a chest roentgenogram. Labial biopsy and sialogram confirmed a diagnosis of SjS. BAL fluid analysis revealed lymphocytosis with a decreased CD4/CD8 ratio compatible with bronchiolitis obliterans organizing pneumonia or lymphoid interstitial pneumonia. Open-lung biopsy specimen, however, showed evidence of UIP. Open-lung biopsy was a useful and necessary examination to determine the nature of the pulmonary complication in primary SjS. Conservative treatment without corticosteroids maintained a stable condition for a follow-up period of 3 years.

journal_name

Chest

journal_title

Chest

authors

Kadota J,Kusano S,Kawakami K,Morikawa T,Kohno S

doi

10.1378/chest.108.6.1756

subject

Has Abstract

pub_date

1995-12-01 00:00:00

pages

1756-8

issue

6

eissn

0012-3692

issn

1931-3543

pii

S0012-3692(15)45147-5

journal_volume

108

pub_type

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