Abstract:
:We describe the first case, to our knowledge, of usual interstitial pneumonia (UIP) as the pulmonary manifestation in primary Sjögren's syndrome (SjS). A 45-year-old woman was admitted to our hospital because of a dry cough and an interstitial shadow on a chest roentgenogram. Labial biopsy and sialogram confirmed a diagnosis of SjS. BAL fluid analysis revealed lymphocytosis with a decreased CD4/CD8 ratio compatible with bronchiolitis obliterans organizing pneumonia or lymphoid interstitial pneumonia. Open-lung biopsy specimen, however, showed evidence of UIP. Open-lung biopsy was a useful and necessary examination to determine the nature of the pulmonary complication in primary SjS. Conservative treatment without corticosteroids maintained a stable condition for a follow-up period of 3 years.
journal_name
Chestjournal_title
Chestauthors
Kadota J,Kusano S,Kawakami K,Morikawa T,Kohno Sdoi
10.1378/chest.108.6.1756subject
Has Abstractpub_date
1995-12-01 00:00:00pages
1756-8issue
6eissn
0012-3692issn
1931-3543pii
S0012-3692(15)45147-5journal_volume
108pub_type
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