Positive Kveim test in patients with coexisting sarcoidosis and human immunodeficiency virus infection.

Abstract:

:We present two cases of sarcoidosis complicated by HIV infection. Each case had a different level of sarcoidosis activity and coexisted with either an AIDS-related infection or a HIV-positive state. Manifestations of sarcoidosis were not apparent in the patient with the AIDS-defining opportunistic infection, but were active in the patient with asymptomatic HIV infection. Both patients had granulomatous reactions to Kveim antigen, and one had such a reaction following an AIDS-defining infection. These findings suggest that non-T-cell mechanisms may be involved in granuloma formation in sarcoidosis.

journal_name

Chest

journal_title

Chest

authors

Amin DN,Sperber K,Brown LK,Chusid ED,Teirstein AS

doi

10.1378/chest.101.5.1454

subject

Has Abstract

pub_date

1992-05-01 00:00:00

pages

1454-6

issue

5

eissn

0012-3692

issn

1931-3543

pii

S0012-3692(16)34167-8

journal_volume

101

pub_type

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