Correlation of leukocyte esterase detection by reagent strips and the presence of neutrophils: a study in BAL fluid.

Abstract:

STUDY OBJECTIVE:In the present study, we evaluated the leukocyte esterase (LE) area of a reagent strip designed for urinalysis for the semiquantitative measurement of the percentage of polymorphonuclear neutrophils (PMNs) in BAL fluid. DESIGN:Prospective. The relative PMN counts (obtained by conventional microscopy and expressed as a percentage of a 500 cell count) of consecutive BAL fluid samples were compared with the corresponding LE categories as read with a urine chemistry reader. LE categories were graded as follows: negative, trace, +, + +, and + + +. RESULTS:A total of 153 BAL fluid samples were included. The mean PMN counts of the negative LE category (4.1 +/- 4.3%; n = 43) and the + + + category (81.8 +/- 16.3%; n = 37) differed significantly from each other and from the mean PMN counts of the other categories. Within the trace, +, and + + categories, a considerable overlap of PMN counts was noted. Assignment of a BAL fluid to the negative LE category consistently predicted a PMN count < 20%. At a threshold value of 50% PMNs, the + + + LE category predicted the BAL fluid samples to the correct group (PMNs > 50% vs < 50%) with a sensitivity of 70.8% and a specificity of 97.1%. CONCLUSIONS:The reagent strips proved to be useful as a rapid test for semiquantitative measurement of the relative PMN counts in BAL fluid. However, the low predictive value for the exclusion of a high PMN count may limit their application.

journal_name

Chest

journal_title

Chest

authors

Jacobs JA,De Brauwer EI,Cornelissen EI,Drent M

doi

10.1378/chest.118.5.1450

subject

Has Abstract

pub_date

2000-11-01 00:00:00

pages

1450-4

issue

5

eissn

0012-3692

issn

1931-3543

pii

S0012-3692(15)51223-3

journal_volume

118

pub_type

杂志文章

相关文献

CHEST文献大全
  • Contribution of craniofacial risk factors in increasing apneic activity among obese and nonobese habitual snorers.

    abstract:STUDY OBJECTIVE:To determine the role of craniofacial risk factors in increasing apneic activity between nonobese and obese habitual snorers. DESIGN:Cross-sectional. SETTING:Care-seeking volunteers identified through advertisements, and referral-based volunteers from two sleep centers serving the greater Cleveland ar...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.111.1.154

    authors: Nelson S,Hans M

    更新日期:1997-01-01 00:00:00

  • Alternatively activated macrophages and airway disease.

    abstract::Macrophages are the most abundant immune cell population in normal lung tissue and serve critical roles in innate and adaptive immune responses as well as the development of inflammatory airway disease. Studies in a mouse model of chronic obstructive lung disease and translational studies of humans with asthma and COP...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.10-2132

    authors: Byers DE,Holtzman MJ

    更新日期:2011-09-01 00:00:00

  • Pulmonary arterial wall distensibility assessed by intravascular ultrasound in children with congenital heart disease: an indicator for pulmonary vascular disease?

    abstract:BACKGROUND:Both pulmonary hypertension and pulmonary overflow are associated with functional and structural changes of the pulmonary arterial wall. Current techniques to evaluate the pulmonary vasculature neglect the pulsatile nature of pulmonary flow. STUDY OBJECTIVES:To determine whether the dynamic properties of th...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.122.2.549

    authors: Berger RM,Cromme-Dijkhuis AH,Hop WC,Kruit MN,Hess J

    更新日期:2002-08-01 00:00:00

  • Captopril lowers coronary venous free radical concentration after direct current cardiac shocks.

    abstract:STUDY OBJECTIVES:Direct current (DC) shocks to the heart cause morphologic and functional myocardial damage. Previous studies have suggested that acute DC shock injury is free radical mediated and that the administration of antioxidant enzymes superoxide dismutase and catalase can reduce the level of DC shock-induced f...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.116.2.484

    authors: Pagan-Carlo LA,Garcia LA,Hutchison JL,Buettner GR,Kerber RE

    更新日期:1999-08-01 00:00:00

  • Deficiency of alveolar fluid glutathione in patients with sepsis and the adult respiratory distress syndrome.

    abstract::The adult respiratory distress syndrome (ARDS) is a devastating clinical illness characterized by refractory hypoxemia and high-permeability pulmonary edema. Reactive oxygen species such as hydrogen peroxide and hypochlorous acid may play a key role in the pathogenesis of the acute lung injury. Glutathione (GSH) is a ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.100.5.1397

    authors: Pacht ER,Timerman AP,Lykens MG,Merola AJ

    更新日期:1991-11-01 00:00:00

  • CT scan features as predictors of patient outcome after bronchial intervention in endobronchial TB.

    abstract:BACKGROUND:The purpose of this study was to identify the CT scan features that predict patient outcome after reexpansion procedures in patients with the fibrotic stage of endobronchial TB. METHODS:We retrospectively enrolled 30 patients (four men, 26 women) aged 32 +/- 11 years who had lobar or whole-lung atelectasis ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.09-1846

    authors: Lee JY,Yi CA,Kim TS,Kim H,Kim J,Han J,Kwon OJ,Lee KS,Chung MJ

    更新日期:2010-08-01 00:00:00

  • Effects of weight loss on peak flow variability, airways obstruction, and lung volumes in obese patients with asthma.

    abstract:STUDY OBJECTIVES:To clarify the pathophysiologic features of the relation between asthma and obesity, we measured the effects of weight reduction on peak expiratory flow (PEF) variability and airways obstruction, compared to simultaneous changes in lung volumes and ventilatory mechanics in obese patients with stable as...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.118.5.1315

    authors: Hakala K,Stenius-Aarniala B,Sovijärvi A

    更新日期:2000-11-01 00:00:00

  • Alternative therapies among adults with a reported diagnosis of asthma or rhinosinusitis : data from a population-based survey.

    abstract:BACKGROUND:Asthma and rhinosinusitis are common medical conditions among adults. Alternative treatments could have important impacts on health status among those individuals with these conditions, but specific prevalence data for these treatments are limited. OBJECTIVE:To estimate the prevalence of specific alternativ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.120.5.1461

    authors: Blanc PD,Trupin L,Earnest G,Katz PP,Yelin EH,Eisner MD

    更新日期:2001-11-01 00:00:00

  • Maximum cardiac output during incremental exercise by first-pass radionuclide ventriculography.

    abstract:STUDY OBJECTIVE:To validate a noninvasive first-pass radionuclide ventriculographic (FPRV) measurement of maximum cardiac output (Qv) during exercise. DESIGN:Comparison of Qv to that measured by the Fick principle (Qf) at peak exercise. SETTING:Academic cardiopulmonary exercise laboratory. PATIENTS:Seventy-eight con...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.114.2.457

    authors: Maroni JM,Oelberg DA,Pappagianopoulos P,Boucher CA,Systrom DM

    更新日期:1998-08-01 00:00:00

  • Lung ultrasound in the diagnosis and follow-up of community-acquired pneumonia: a prospective, multicenter, diagnostic accuracy study.

    abstract:BACKGROUND:The aim of this prospective, multicenter study was to define the accuracy of lung ultrasound (LUS) in the diagnosis of community-acquired pneumonia (CAP). METHODS:Three hundred sixty-two patients with suspected CAP were enrolled in 14 European centers. At baseline, history, clinical examination, laboratory ...

    journal_title:Chest

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1378/chest.12-0364

    authors: Reissig A,Copetti R,Mathis G,Mempel C,Schuler A,Zechner P,Aliberti S,Neumann R,Kroegel C,Hoyer H

    更新日期:2012-10-01 00:00:00

  • Diagnosis of superior vena caval obstruction by transesophageal echocardiography.

    abstract::Superior vena caval (SVC) syndrome may be caused by extravascular compression or intravascular obstruction. Knowing the mechanism of SVC syndrome enables the physician to choose appropriate treatment. Transesophageal echocardiography (TEE) is a safe bedside procedure that is excellent for evaluating the SVC and its su...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.101.3.874

    authors: Ayala K,Chandrasekaran K,Karalis DG,Parris TM,Ross JJ Jr

    更新日期:1992-03-01 00:00:00

  • The pulmonary response to fiberglass dust. Report of the Committee on Environmental Health. American College of Chest Physicians.

    abstract::Fiberglass inhalation seems to produce a minimal tissue response in the lungs, and the reaction is one of macrophagic mobilization and is characteristic of the pulmonary response to those nonfibrogenic dusts classified as nuisance dusts. In order to merit the designation of a nuisance dust, the pulmonary response must...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:

    authors:

    更新日期:1976-02-01 00:00:00

  • Copeptin, C-reactive protein, and procalcitonin as prognostic biomarkers in acute exacerbation of COPD.

    abstract:BACKGROUND:A novel approach to estimate the severity of COPD exacerbation and predict its outcome is the use of biomarkers. We assessed circulating levels of copeptin, the precursor of vasopressin, C-reactive protein (CRP), and procalcitonin as potential prognostic parameters for in-hospital and long-term outcomes in p...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.06-2336

    authors: Stolz D,Christ-Crain M,Morgenthaler NG,Leuppi J,Miedinger D,Bingisser R,Müller C,Struck J,Müller B,Tamm M

    更新日期:2007-04-01 00:00:00

  • Characteristics of airway inflammation and bronchodilator reversibility in COPD: a potential guide to treatment.

    abstract:STUDY OBJECTIVES:The management of stable patients with COPD depends on the severity of symptoms and airflow limitation. Regarding inflammation, corticosteroids are the only medications that are recommended for use, and only under restricted circumstances. Corticosteroids tend to undertreat or overtreat patients with C...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.126.2.375

    authors: Perng DW,Huang HY,Chen HM,Lee YC,Perng RP

    更新日期:2004-08-01 00:00:00

  • Dyphylline aerosol attenuates antigen-induced bronchoconstriction in experimental canine asthma.

    abstract::This study compared the bronchodilator effect in experimental canine asthma of dyphylline administered by aerosol and intravenous routes in doses producing equivalent concentrations of the drug in the plasma. Pulmonary resistance (RL) was calculated from simultaneous measurements of pressure and flow during fixed-volu...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.79.4.454

    authors: Hirshman CA,Lawyer C,Downes H,Farbood A,Rodgers R,Gerber N

    更新日期:1981-04-01 00:00:00

  • Laryngotracheoscopic findings in long-term follow-up after Griggs tracheostomy.

    abstract:OBJECTIVE:Analysis of laryngotracheoscopic findings of the upper airway tract following percutaneous tracheostomy using the technique according to Griggs. DESIGN:Retrospective cohort study PATIENTS:Nineteen of 32 long-term surviving patients (mean follow-up duration, 17 months; range, 11 to 23 months) underwent a mod...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.122.1.206

    authors: Dollner R,Verch M,Schweiger P,Deluigi C,Graf B,Wallner F

    更新日期:2002-07-01 00:00:00

  • Left subclavian steal, interrupted aortic arch, complete transposition of the great vessels and single left ventricle.

    abstract::Congenital subclavian steal consists of atresia of the proximal end of the subclavian artery, while the blood supply to the distal portion of the subclavian artery originates from the circle of Willis. It should be suspected in complicated malformations of the heart associated with marked hypoplasia or interruption of...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.67.3.352

    authors: Garcia O,Wilkins R,Cunha D,Jesse MJ

    更新日期:1975-03-01 00:00:00

  • Effect of a nasogastric tube on esophageal pressure measurement in normal adults.

    abstract::We studied the correspondence between fluctuations of esophageal pressure measured before and after placement of a nasogastric (NG) tube in six normal volunteers. Flow, airway pressure, and esophageal pressure data from at least 20 breaths were recorded in seven ventilatory conditions in two body postures: 0 degree (s...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.106.1.137

    authors: Niknam J,Chandra A,Adams AB,Nahum A,Ravenscraft SA,Marini JJ

    更新日期:1994-07-01 00:00:00

  • Posaconazole therapy for chronic refractory coccidioidomycosis.

    abstract:BACKGROUND:Coccidioides infections often result in chronic relapsing disease that presents a challenge to the currently available therapy. Posaconazole, an oral extended-spectrum triazole agent, has been shown in vitro and in vivo to have potent activity against this fungus. METHODS:An open-label multinational study o...

    journal_title:Chest

    pub_type: 杂志文章,多中心研究

    doi:10.1378/chest.07-0114

    authors: Stevens DA,Rendon A,Gaona-Flores V,Catanzaro A,Anstead GM,Pedicone L,Graybill JR

    更新日期:2007-09-01 00:00:00

  • Childhood parapneumonic effusions: biochemical and inflammatory markers.

    abstract:STUDY OBJECTIVES:Biochemical and inflammatory markers in pleural inflammation were evaluated in pediatric cases of parapneumonic effusions, and interleukin (IL)-8 and tumor necrosis factor (TNF)-alpha concentrations were tested for possible differentiation of the complicated nature of effusions. PATIENTS:Twenty-eight ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.128.3.1436

    authors: Utine GE,Ozcelik U,Yalcin E,Dogru D,Kiper N,Aslan A,Kanra G

    更新日期:2005-09-01 00:00:00

  • Minimal effect of alcohol ingestion on breathing during the sleep of postmenopausal women.

    abstract::Eighteen asymptomatic postmenopausal women volunteered to ingest 2 ml of 100-proof vodka per kg of body weight in orange juice on one night and a placebo on another. Overnight sleep monitoring was performed immediately thereafter. Alcohol ingestion caused reduction in total sleep time from 329 to 281 minutes and a dec...

    journal_title:Chest

    pub_type: 临床试验,杂志文章

    doi:10.1378/chest.88.2.181

    authors: Block AJ,Hellard DW,Slayton PC

    更新日期:1985-08-01 00:00:00

  • Effect of dry warm air on respiratory water loss in children with exercise-induced asthma.

    abstract::The variation in respiratory water loss (RWL) over time, expressed as the mass of water vapor lost per liter (body temperature and pressure, saturated) of ventilation (MH2O), was investigated in two groups: (1) children with exercise-induced asthma; and (2) healthy children. Children were matched for age and sex and w...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.94.1.81

    authors: Tabka Z,Ben Jebria A,Vergeret J,Guenard H

    更新日期:1988-07-01 00:00:00

  • Comparison of the effectiveness of tetracycline and minocycline as pleural sclerosing agents in rabbits.

    abstract::Parenteral tetracycline, one of the most commonly used agents for producing pleurodesis, is no longer available because of stricter regulations governing the manufacturing process. The objective of this project was to determine whether minocycline, a tetracycline derivative, is an effective sclerosant in an experiment...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.106.2.577

    authors: Light RW,Wang NS,Sassoon CS,Gruer SE,Vargas FS

    更新日期:1994-08-01 00:00:00

  • The prevalence and predictors of respiratory-related work limitation and occupational disability in an international study.

    abstract:BACKGROUND:Work-related symptoms and disability due to respiratory disease are common and costly among working-age adults. To investigate this problem, we analyzed data on respiratory symptoms related to the workplace and occupational disability from the European Community Respiratory Health Survey (ECRHS). METHODS:Th...

    journal_title:Chest

    pub_type: 杂志文章,多中心研究

    doi:

    authors: Blanc PD,Burney P,Janson C,Torén K

    更新日期:2003-09-01 00:00:00

  • Distinguishing Smoking-Related Lung Disease Phenotypes Via Imaging and Molecular Features.

    abstract:BACKGROUND:Chronic tobacco smoke exposure results in a broad range of lung pathologies including emphysema, airway disease and parenchymal fibrosis as well as a multitude of extra-pulmonary comorbidities. Prior work using CT imaging has identified several clinically relevant subgroups of smoking related lung disease, b...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1016/j.chest.2020.08.2115

    authors: Billatos E,Ash SY,Duan F,Xu K,Romanoff J,Marques H,Moses E,Han MK,Regan EA,Bowler RP,Mason SE,Doyle TJ,San José Estépar R,Rosas IO,Ross JC,Xiao X,Liu H,Liu G,Sukumar G,Wilkerson M,Dalgard C,Stevenson C,Whitney

    更新日期:2020-09-16 00:00:00

  • Occupational risk factors for sarcoidosis in African-American siblings.

    abstract:OBJECTIVES:To determine whether certain occupations and occupationally related exposures were associated with a history of sarcoidosis in African-American siblings. METHODS:We collected occupational data from 921 African Americans in 273 sibships that had been identified through a sarcoidosis case. Among the 648 sibli...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.123.5.1527

    authors: Kucera GP,Rybicki BA,Kirkey KL,Coon SW,Major ML,Maliarik MJ,Iannuzzi MC

    更新日期:2003-05-01 00:00:00

  • Ca2+ movements in smooth muscle.

    abstract::We describe the Ca2+ movements in smooth muscle cells at rest and during activation and relaxation as deduced from transplasmalemmal Ca2+ fluxes and contractile respnses. The general picture which emerges is: the resting cell has a [Ca2+]cyt below 10(-7) M and large gradients are poised across both the cell membrane a...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.78.1_supplement.157

    authors: van Breemen C,Aaronson P,Loutzenhiser R,Meisheri K

    更新日期:1980-07-01 00:00:00

  • Systolic time intervals in atrial fibrillation.

    abstract::Forty patients with atrial fibrillation and 20 patients with congestive heart failure and sinus rhythm were studied. Patients were divided into two groups. Group A consisted of 20 patients with atrial fibrillation in whom systolic time intervals were measured. Twenty to 50 beats were analyzed. Five of the patients had...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.74.6.629

    authors: Boudoulas H,Lewis RP,Sherman JA,Bush CA,Dalamangas G,Forester WF

    更新日期:1978-12-01 00:00:00

  • Recent Dieulafoy's lesion bleeding and massive pulmonary emboli. Successful use of thrombolytic therapy.

    abstract::A massive GI bleed secondary to a Dieulafoy's lesion developed in a 77-year-old woman. Fifteen days later, massive pulmonary emboli developed. We describe successful thrombolytic treatment of her pulmonary emboli without complicating GI hemorrhage. ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.110.2.567

    authors: Levin MS,Vernovsky I,Beer DJ

    更新日期:1996-08-01 00:00:00

  • Performance measurement through audit, feedback, and profiling as tools for improving clinical care.

    abstract::Clinical audits and practice profiling have become popular tools in the attempt to change physician behavior to improve quality of care. Unfortunately, the growing need for information on quality of care has often outpaced the development of standard, valid, and reliable approaches to using these tools. The studies of...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.118.2_suppl.53s

    authors: Weiss KB,Wagner R

    更新日期:2000-08-01 00:00:00