Cysteinyl leukotrienes in allergic inflammation: strategic target for therapy.

abstract：BACKGROUND:Pathogenic bacteria colonize the airways of 30% to 40% of patients with COPD and cause approximately 50% of exacerbations. New strains of nontypeable Haemophilus influenzae (NTHI) and Moraxella catarrhalis are associated with exacerbations. Antimicrobial protein/peptides (AMPs) play important roles in innate...

journal_title：Chest

authors： Parameswaran GI,Sethi S,Murphy TF

更新日期：2011-09-01 00:00:00

abstract：:We report three cases of organophosphate (OP) poisoning. One patient was a 19-year-old woman who drank OP compounds in an attempt at suicide. The other two patients became intoxicated on the way to the hospital during mouth-to-mouth breathing. The first patient died in the emergency department, and the other two were ...

journal_title：Chest

authors： Koksal N,Buyukbese MA,Guven A,Cetinkaya A,Hasanoglu HC

更新日期：2002-08-01 00:00:00

abstract：:This commentary heralds the recognition in China of a new subspecialty, Pulmonary and Critical Care Medicine, and the first national fellowship training pathway in any medical specialty. Because of striking environmental health-care similarities that existed in the United States, the Chinese medical community decided ...

journal_title：Chest

authors： Qiao R,Rosen MJ,Chen R,Wu S,Marciniuk D,Wang C,CTS-ACCP Pulmonary and Critical Care Medicine Workgroup.

更新日期：2014-01-01 00:00:00

abstract：:Fever, dyspnea, dry cough and interstitial fibrosis occurred in a man with prostate carcinoma treated with nilutamide and buserelin for two and one-half months. The diagnosis of drug-induced fibrosis was established on the basis of chronologic and semiologic events. This is the first such case reported. ...

journal_title：Chest

authors： Seigneur J,Trechot PF,Hubert J,Lamy P

更新日期：1988-05-01 00:00:00

abstract：OBJECTIVES:Cognitive impairment increases with age, as do many serious illnesses requiring intensive care. Little is known, however, about physician recognition of preexisting cognitive impairment in the ICU and which patient factors may play a role in physician recognition. DESIGN:Cross-sectional comparative study. ...

journal_title：Chest

authors： Pisani MA,Redlich C,McNicoll L,Ely EW,Inouye SK

更新日期：2003-12-01 00:00:00

abstract：BACKGROUND:To develop an evidence-based approach to follow-up of patients after curative intent therapy for lung cancer. METHODS:Guidelines on lung cancer diagnosis and management published between 2002 and December 2005 were identified by a systematic review of the literature, and supplemental material appropriate to...

journal_title：Chest

authors： Rubins J,Unger M,Colice GL,American College of Chest Physicians.

更新日期：2007-09-01 00:00:00

abstract：STUDY OBJECTIVES:Direct current (DC) shocks to the heart cause morphologic and functional myocardial damage. Previous studies have suggested that acute DC shock injury is free radical mediated and that the administration of antioxidant enzymes superoxide dismutase and catalase can reduce the level of DC shock-induced f...

journal_title：Chest

authors： Pagan-Carlo LA,Garcia LA,Hutchison JL,Buettner GR,Kerber RE

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND:Early high-dose IV vitamin C is being investigated as adjuvant therapy in patients who are critically ill, but the optimal dose and infusion method are unclear. The primary aim of this study was to describe the dose-plasma concentration relationship and safety of four different dosing regimens. METHODS:This...

journal_title：Chest

authors： de Grooth HJ,Manubulu-Choo WP,Zandvliet AS,Spoelstra-de Man AME,Girbes AR,Swart EL,Oudemans-van Straaten HM

更新日期：2018-06-01 00:00:00

abstract：:The use of portable monitors (PM) devices has been demonstrated in a wide variety of investigational settings with varying results. While most devices correlate very well with in-laboratory polysomnography, some still misclassify a significant numbers of patients and have lower sensitivity. In addition, the failure ra...

journal_title：Chest

authors： Ahmed M,Patel NP,Rosen I

更新日期：2007-11-01 00:00:00

abstract：:A prospective study was done to compare four different methods of securing oral endotracheal tubes: adhesive tape (A), Twill tape (T), Twill tape with FlexBlue bite block (TFXB), and Velcro tie with FlexBlue (VFXB), used on sequential days. Thirty-six patients were enrolled for 136 patient-days and 18 had complete 4-d...

journal_title：Chest

authors： Levy H,Griego L

更新日期：1993-11-01 00:00:00

abstract：OBJECTIVE:Assessment of patient preferences for attributes of asthma treatments. METHODS:Two hundred ninety-eight patients (age range, 18 to 60 years) from 15 centers in Sweden completed a questionnaire concerning their asthma, and ranked 18 alternative treatments using conjoint analysis. Patients were receiving treat...

journal_title：Chest

authors： Johansson G,Ställberg B,Tornling G,Andersson S,Karlsson GS,Fält K,Berggren F

更新日期：2004-03-01 00:00:00

abstract：:The acute and chronic effects of fire fighting on pulmonary function were studied in 54 fire fighters from Connecticut, 32 smokers and 22 nonsmokers. Baseline studies of maximum expiratory flow-volume curves while breathing air and a mixture of 80 percent helium and 20 percent oxygen revealed obstruction of the small ...

journal_title：Chest

authors： Loke J,Farmer W,Matthay RA,Putman CE,Smith GJ

更新日期：1980-03-01 00:00:00

abstract：:Pulmonary sequestration is a congenital anomaly resulting in nonfunctioning lung tissue in either the "extralobar" or "intralobar" position. Both forms derive their blood supply from the systemic circulation. Large pulmonary sequestrations can present in the newborn with potentially fatal respiratory distress. Surgica...

journal_title：Chest

authors： Piccione W Jr,Burt ME

更新日期：1990-01-01 00:00:00

abstract：:Previous studies have described oxygen delivery (DO2) and oxygen consumption (VO2) relationships in patients with ARDS and other acute diseases that suggest occasions when VO2 may be dependent on the supply of oxygen, ie, DO2. We studied 127 postoperative patients who developed ARDS to evaluate the relationship of DO2...

journal_title：Chest

authors： Appel PL,Shoemaker WC

更新日期：1992-09-01 00:00:00

abstract：:Echocardiographic examination in a patient with primary pulmonary hypertension demonstrated midsystolic closure of the aortic valve, which has often been described in hypertrophic cardiomyopathy with or without obstruction, in discrete subaortic stenosis, and in ruptured aneurysm of the right coronary sinus of Valsalv...

journal_title：Chest

authors： Doi YL,Bishop RL,Sugiura T,Spodick DH

更新日期：1981-06-01 00:00:00

abstract：SETTING:Seven primary health clinics and a pulmonary disease specialty clinic in Rio de Janeiro City, Brazil. OBJECTIVE:To evaluate a commercial immunochromatographic test kit (ICT Tuberculosis; AMRAD-ICT; Sidney, Australia) employing five recombinant Mycobacterium tuberculosis proteins for the detection of pulmonary ...

journal_title：Chest

authors： Perkins MD,Conde MB,Martins M,Kritski AL

更新日期：2003-01-01 00:00:00

abstract：:Every year, millions of patients are diagnosed with pulmonary nodules, and as increasing numbers of people undergo lung cancer screening, even more patients will be found to have a nodule. The vast majority of patients cannot benefit from the detection of a pulmonary nodule because most are benign. Accordingly, it is ...

journal_title：Chest

authors： Slatore CG,Wiener RS

更新日期：2018-04-01 00:00:00

abstract：:Poverty is a major social problem in the United States and throughout much of the world. Poverty and the broader term socioeconomic status (SES) are important determinants of overall health status and many pulmonary diseases. The purpose of this study was to review the medical literature from the past 20 years address...

journal_title：Chest

authors： Hegewald MJ,Crapo RO

更新日期：2007-11-01 00:00:00

abstract：:A 17-year-old girl with primary pulmonary hypertension was treated with longterm administration of oxygen. Oxygen was delivered only at night for eight hours daily. Her clinical status has been improved for more than 17 months. Cardiac catheterization revealed almost 50 percent reduction of pulmonary vascular resistan...

journal_title：Chest

authors： Nagasaka Y,Akutsu H,Lee YS,Fujimoto S,Chikamori J

更新日期：1978-09-01 00:00:00

abstract：:A 60-year-old man presented with features of superior vena cava (SVC) obstruction. On evaluation, he was diagnosed as having angioimmunoblastic lymphadenopathy with dysproteinemia (AILD). SVC obstruction due to AILD, to our knowledge, has not been described. ...

journal_title：Chest

authors： Sanghvi S,Kothari AS,Hathi BC,Sharma RG

更新日期：1991-12-01 00:00:00

abstract：BACKGROUND:Spontaneous pneumothorax (SPTX) is an uncommon phenomenon in the general population and is most commonly associated with prior bulbous emphysema, cystic parenchymal lung disease, and tuberculous lung disease. A rare cause of SPTX is malignant disease, either in the form of primary lung or pleural cancers, or...

journal_title：Chest

authors： Hoag JB,Sherman M,Fasihuddin Q,Lund ME

更新日期：2010-09-01 00:00:00

abstract：:The influence of positive expiratory pressure (PEP) applied during inhalation of a beta 2-agonist in treatment of bronchial asthma was investigated in a randomized crossover study with two-week treatment periods. In one period, two puffs (0.5 mg) of terbutaline was given from a metered dose inhaler and inhaled through...

journal_title：Chest

authors： Frischknecht-Christensen E,Nørregaard O,Dahl R

更新日期：1991-08-01 00:00:00

abstract：STUDY OBJECTIVES:We sought to compare arterial oxygen partial pressure (PaO2) relationships between a 15.1% hypoxia inhalation test (HIT) at sea level and a hypobaric chamber exposure equivalent to 2,438 m (8,000 feet) of altitude above sea level in patients with chronic obstructive pulmonary disease (COPD) and healthy...

journal_title：Chest

authors： Dillard TA,Moores LK,Bilello KL,Phillips YY

更新日期：1995-02-01 00:00:00

abstract：:Men who snore heavily have an increased incidence of hypertension, angina, stroke, and neuropsychologic dysfunction, which may be due to nocturnal oxygen desaturation. Nocturnal oxygen therapy might be beneficial to such individuals by improving oxygenation and relieving tissue hypoxia. Twenty-eight asymptomatic heavy...

journal_title：Chest

authors： Block AJ,Hellard DW,Cicale MJ

更新日期：1987-09-01 00:00:00

abstract：:Nodular opacities are a well-known pulmonary manifestation of rheumatoid arthritis (RA), occurring most often in seropositive men who smoke and have subcutaneous nodules. In the past 15 years two cases of lung carcinoma presenting as pulmonary nodules have been reported in patients with rheumatoid disease. We present ...

journal_title：Chest

authors： Jolles H,Moseley PL,Peterson MW

更新日期：1989-11-01 00:00:00

abstract：:To evaluate whether epithelial damage of airways in asthma could be related to diminished levels of the low molecular weight bronchial leukocyte proteinase inhibitor (BLPI) in airways, we determined BLPI in bronchial washings of 13 asthma patients and 13 healthy subjects, using a sensitive enzyme-linked immunoassay. T...

journal_title：Chest

authors： Ochnio JJ,Abboud RT,Lam S,Johal SS,Smith CE,Johnson DA

更新日期：1988-05-01 00:00:00

abstract：:We attempted to assess recent changes in the prevalence of physician-diagnosed asthma and the possible influence of diagnostic exchange on these trends. The routinely collected data of the provincial Health Insurance Plan (physicians' claims) were used to determine the annual prevalence of physician-diagnosed asthma i...

journal_title：Chest

authors： Manfreda J,Becker AB,Wang PZ,Roos LL,Anthonisen NR

更新日期：1993-01-01 00:00:00

abstract：:Dyspnea after polio can occur for a variety of reasons, including neuromuscular disease and upper airway abnormalities resulting from prolonged intubation, including tracheal stenosis, tracheomalacia, and vocal cord paralysis. Routine studies such as spirometry and maximum voluntary ventilation (MVV) measurements can ...

journal_title：Chest

authors： Knobil K,Becker FS,Harper P,Graf LB,Wolf GT,Martinez FJ

更新日期：1994-03-01 00:00:00

abstract：:Several reports in the literature and our experience prior to 1974 support the thesis that operative risk in patients with acquired heart disease and poor ventricular function (as assessed by a biplane ejection fraction [EF] less than or equal to 0.40) was very significantly increased over the risk in patients with no...

journal_title：Chest

authors： Tyers GF,Williams DR,Babb JD,Levenson L,Zelis RF,Waldhausen JA

更新日期：1977-03-01 00:00:00

abstract：:A review of the largest observational studies on post-ICU weaning from prolonged mechanical ventilation yields evidence that more than half of such patients can be successfully liberated from mechanical ventilation. Success is likely to fall within a 3-month window, with late successes and partial ventilator independe...

journal_title：Chest

authors： Scheinhorn DJ,Chao DC,Hassenpflug MS,Gracey DR

更新日期：2001-12-01 00:00:00