Abstract:
:Nodular opacities are a well-known pulmonary manifestation of rheumatoid arthritis (RA), occurring most often in seropositive men who smoke and have subcutaneous nodules. In the past 15 years two cases of lung carcinoma presenting as pulmonary nodules have been reported in patients with rheumatoid disease. We present seven patients with seropositive RA and subcutaneous nodules who had new pulmonary nodule(s) noted on chest roentgenograms. All but one were current smokers. Carcinoma was found in all patients at bronchoscopy or thoracotomy. Four patients had solitary nodules (one was cavitary); the remaining three patients had multiple bilateral nodules that cavitated in one case. All patients had interstitial abnormality (peribronchial/vascular thickening) with basal predominance in three, and there was evidence of pleural thickening/fluid in three patients. These results strongly suggest that histologic proof of presumed rheumatoid pulmonary nodules be obtained.
journal_name
Chestjournal_title
Chestauthors
Jolles H,Moseley PL,Peterson MWdoi
10.1378/chest.96.5.1022subject
Has Abstractpub_date
1989-11-01 00:00:00pages
1022-5issue
5eissn
0012-3692issn
1931-3543pii
S0012-3692(16)35120-0journal_volume
96pub_type
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