Nodular pulmonary opacities in patients with rheumatoid arthritis. A diagnostic dilemma.

Abstract:

:Nodular opacities are a well-known pulmonary manifestation of rheumatoid arthritis (RA), occurring most often in seropositive men who smoke and have subcutaneous nodules. In the past 15 years two cases of lung carcinoma presenting as pulmonary nodules have been reported in patients with rheumatoid disease. We present seven patients with seropositive RA and subcutaneous nodules who had new pulmonary nodule(s) noted on chest roentgenograms. All but one were current smokers. Carcinoma was found in all patients at bronchoscopy or thoracotomy. Four patients had solitary nodules (one was cavitary); the remaining three patients had multiple bilateral nodules that cavitated in one case. All patients had interstitial abnormality (peribronchial/vascular thickening) with basal predominance in three, and there was evidence of pleural thickening/fluid in three patients. These results strongly suggest that histologic proof of presumed rheumatoid pulmonary nodules be obtained.

journal_name

Chest

journal_title

Chest

authors

Jolles H,Moseley PL,Peterson MW

doi

10.1378/chest.96.5.1022

subject

Has Abstract

pub_date

1989-11-01 00:00:00

pages

1022-5

issue

5

eissn

0012-3692

issn

1931-3543

pii

S0012-3692(16)35120-0

journal_volume

96

pub_type

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