Prospective analysis of cystic fibrosis transmembrane regulator mutations in adults with bronchiectasis or pulmonary nontuberculous mycobacterial infection.

abstract：:The preponderance of evidence indicates that high airway pressure is not by itself injurious to the lung. Rather, overdistention of the lung appears to be the fundamental mechanism underlying VALI. The physician must bear in mind the factors (ie, flow-resistive pressure losses, respiratory muscle activity, and abnorma...

journal_title：Chest

authors： Manning HL

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:Long-acting muscarinic antagonist (LAMA)/long-acting β2-agonist (LABA) combinations are a treatment option for patients with COPD who continue to have symptoms despite treatment with a LAMA or a LABA alone. The Efficacy and Safety of PT003, PT005, and PT001 in Subjects with Moderate-to-Very Severe COPD (PINN...

journal_title：Chest

authors： Martinez FJ,Rabe KF,Ferguson GT,Fabbri LM,Rennard S,Feldman GJ,Sethi S,Spangenthal S,Gottschlich GM,Rodriguez-Roisin R,Arora S,Siler TM,Siddiqui S,Darken P,Fischer T,Maes A,Golden M,Orevillo C,Reisner C

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Lung cancer screening (LCS) is an important secondary prevention measure to reduce lung cancer mortality. The goal of this study was to assess state-level variations in LCS among the US elderly during the first 3 years since Medicare began its LCS reimbursement policy in 2015. METHODS:This ecological study ...

journal_title：Chest

authors： Liu B,Dharmarajan K,Henschke CI,Taioli E

更新日期：2020-04-01 00:00:00

abstract：STUDY OBJECTIVE:To evaluate the interaction between craniofacial structure and obesity in male patients with obstructive sleep apnea (OSA). DESIGN:Retrospective analysis of a cohort of OSA patients. The relationships between neck circumference (NC), body mass index, apnea severity, and craniofacial and upper airway so...

journal_title：Chest

authors： Ferguson KA,Ono T,Lowe AA,Ryan CF,Fleetham JA

更新日期：1995-08-01 00:00:00

abstract：:A 60-pack-year smoker presented with cough, dyspnea and orthopnea of three months' duration. Spirometry revealed severe reduction in maximal expiratory flow; CT of the chest and bronchoscopy demonstrated expiratory collapse of a mid-tracheal segment, and a presumptive diagnosis of tracheomalacia was made. A right late...

journal_title：Chest

authors： Dunn WF,Hubmayr RD,Pairolero PC,Sheedy PF,Edell ES,Nelson SB

更新日期：1990-04-01 00:00:00

abstract：:In an effort to characterize the effectiveness of cardiology consultation, the outcomes of consultants' recommendations for diagnostic actions and cardiac drugs were quantitatively examined in 394 cases. Drug recommendations were made more frequently (49 percent) than diagnostic recommendations (38 percent) and were a...

journal_title：Chest

authors： Mackenzie TB,Popkin MK,Callies AL,Jorgensen CR,Cohn JN

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND:The synthetic peptide solnatide is a novel pharmacologic agent that reduces extravascular lung water, blunts reactive oxygen species production, and improves lung function due to its ability to directly activate the epithelial sodium channel. The goal of this study was to investigate the effect of solnatide ...

journal_title：Chest

authors： Zhou Q,Wang D,Liu Y,Yang X,Lucas R,Fischer B

更新日期：2017-03-01 00:00:00

abstract：:An unusual case of Staphylococcus aureus endocarditis confined to the mural left atrium is presented. Echocardiographic studies revealed a 1.5 x 2.0-cm vegetation mimicking a myxoma situated in the path of a mitral regurgitant jet on a color Doppler test. Emboli to upper and lower extremities and brain complicated the...

journal_title：Chest

authors： Bierbrier GS,Novick RJ,Guiraudon C,Wisenberg G,Boughner D

更新日期：1991-03-01 00:00:00

abstract：:We studied the reproducibility of tests of RM performance in normal elderly subjects and compared their performance with that of patients with COPD. The RM strength was measured as MIP and MEP. The RM endurance was measured using a two-minute incremental threshold loading test. The max load, the average Ppk as %MIP at...

journal_title：Chest

authors： Morrison NJ,Richardson J,Dunn L,Pardy RL

更新日期：1989-01-01 00:00:00

abstract：STUDY OBJECTIVES:To evaluate, through clinical and transthoracic echocardiography (TTE) follow-up, the natural history of persistent pericardial effusion (PE) after postoperative day 15 in patients who were given and were not given anticoagulant therapy. DESIGN AND PATIENTS:We retrospectively studied a cohort of 1,277...

journal_title：Chest

authors： Meurin P,Weber H,Renaud N,Larrazet F,Tabet JY,Demolis P,Ben Driss A

更新日期：2004-06-01 00:00:00

abstract：:The incidence of distal esophageal adenocarcinoma and primary proximal gastric carcinoma has increased substantially in the past 15 years, particularly in North America and in some European countries. Patients with curatively resected cancer consistently have a 10 to 20% 5-year survival rate. Radiation therapy alone s...

journal_title：Chest

authors： Ajani JA

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Although diaphragmatic motion is readily studied by ultrasonography, the procedure remains poorly codified. The aim of this prospective study was to determine the reference values for diaphragmatic motion as recorded by M-mode ultrasonography. METHODS:Two hundred ten healthy adult subjects (150 men, 60 wome...

journal_title：Chest

authors： Boussuges A,Gole Y,Blanc P

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:The impact of new-onset postoperative atrial fibrillation (NAF) on in-hospital mortality (IHM) following cardiac surgery is unknown. METHODS:All patients without preoperative atrial fibrillation undergoing isolated coronary artery bypass graft surgery (CABG) and concomitant CABG and valve surgery were ident...

journal_title：Chest

authors： Kalavrouziotis D,Buth KJ,Ali IS

更新日期：2007-03-01 00:00:00

abstract：:We report a case of pleural dissemination of invasive thymoma, which was successfully treated with intrathoracic chemothermotherapy following panpleuropneumonectomy. Intrathoracic chemothermotherapy in combination with surgery may be a hopeful adjuvant treatment to control pleural disseminated lesions of invasive thym...

journal_title：Chest

authors： Higashiyama M,Doi O,Kodama K,Yokouchi H

更新日期：1994-06-01 00:00:00

abstract：BACKGROUND:In adult patients, the consistent use of language to describe dyspnea enhances patient-provider communication and contributes to diagnostic and therapeutic decisions. The objective of this research was to determine whether pediatric patients similarly display consistency in the language used to describe "unc...

journal_title：Chest

authors： Harver A,Schwartzstein RM,Kotses H,Humphries CT,Schmaling KB,Mullin ML

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Critically ill patients who develop ARDS have substantial associated morbidity and mortality. Circulating mitochondrial DNA (mtDNA) released during critical illness causes endothelial dysfunction and lung injury in experimental models. This study hypothesized that elevated plasma mtDNA is associated with ARD...

journal_title：Chest

authors： Faust HE,Reilly JP,Anderson BJ,Ittner CAG,Forker CM,Zhang P,Weaver BA,Holena DN,Lanken PN,Christie JD,Meyer NJ,Mangalmurti NS,Shashaty MGS

更新日期：2020-01-01 00:00:00

abstract：STUDY OBJECTIVE:Spirometry is performed to monitor lung health, but variability between tests can hinder recognition of excessive FEV(1) declines. We sought to describe the relationship between FEV(1) changes over 1 to 5 years and FEV(1) declines over longer terms, using 21,821 test results from 1,884 workers who parti...

journal_title：Chest

authors： Wang ML,Avashia BH,Petsonk EL

更新日期：2006-08-01 00:00:00

abstract：OBJECTIVES:To compare the systemic bioavailability (assessed by cortisol suppression) of high-dose budesonide when given by four inhaler devices and orally. Also studied are the relative systemic potencies of three inhaled steroids (budesonide, fluticasone propionate, and beclomethasone dipropionate) when given by mete...

journal_title：Chest

authors： Wales D,Makker H,Kane J,McDowell P,O'Driscoll BR

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND:Inspiratory muscle weakness and abnormalities in breathing pattern and in respiratory drive have been reported in patients with multisystem disorders. In patients with systemic lupus erythematosus (SLE), data on respiratory muscle strength and control of breathing are scarce. METHODS:We studied a subset of ...

journal_title：Chest

authors： Scano G,Goti P,Duranti R,Misuri G,Emmi L,Rosi E

更新日期：1995-09-01 00:00:00

abstract：OBJECTIVE:Postoperative pulmonary hypertension (POPH) substantially increases mortality after repair of congenital heart diseases. Inhaled nitric oxide (NO) has been reported as an effective and specific means of controlling POPH crisis. No randomized, placebo-controlled study has addressed the ability of NO administra...

journal_title：Chest

authors： Journois D,Baufreton C,Mauriat P,Pouard P,Vouhé P,Safran D

更新日期：2005-11-01 00:00:00

abstract：:These studies show the results of intensive care management of 306 consecutive patients with tetanus compared with 335 patients treated conservatively in the same hospital before the institution of the ICU. The impact of the ICU treatment was manifested in a decrease in mortality, from 43.58 percent to 15 percent. In ...

journal_title：Chest

authors： Trujillo MH,Castillo A,España J,Manzo A,Zerpa R

更新日期：1987-07-01 00:00:00

abstract：INTRODUCTION:Osteoporosis is a common condition in patients with end-stage lung disease, but little attention has been given to bone disease in patients with primary pulmonary hypertension (PPH). The purposes of this study were as follows: (1) to determine the prevalence of osteoporosis in patients with severe PPH befo...

journal_title：Chest

authors： Tschopp O,Schmid C,Speich R,Seifert B,Russi EW,Boehler A

更新日期：2006-04-01 00:00:00

abstract：:A prospective study of community-acquired pneumonia in Hong Kong was carried out between January and December, 1988. Ninety adults (57 male) with a mean age of 57.3 years were admitted to the Prince of Wales Hospital with community-acquired pneumonia. The etiologic diagnosis of pneumonia was made in 37 cases (41 perce...

journal_title：Chest

authors： Chan CH,Cohen M,Pang J

更新日期：1992-02-01 00:00:00

abstract：BACKGROUND:Failure to reliably diagnose ARDS may be a major driver of negative clinical trials and underrecognition and treatment in clinical practice. We sought to examine the interobserver reliability of the Berlin ARDS definition and examine strategies for improving the reliability of ARDS diagnosis. METHODS:Two hu...

journal_title：Chest

authors： Sjoding MW,Hofer TP,Co I,Courey A,Cooke CR,Iwashyna TJ

更新日期：2018-02-01 00:00:00

abstract：:The role of thoracic radiation therapy in the management of limited-stage small cell lung cancer (SCLC) is reviewed. Although chest irradiation has been used to treat SCLC for over four decades, its standard role in the management of limited-stage disease was established only during the last decade. Multiple prospecti...

journal_title：Chest

authors： Kumar P

更新日期：1997-10-01 00:00:00

abstract：STUDY OBJECTIVES:To assess exercise tolerance and determine the distinct role of cardiac, respiratory, or peripheral factors on it after delayed surgical repair in patients with tetralogy of Fallot. DESIGN:The aerobic exercise capacity of 15 adult patients (mean [+/- SD] age, 21 +/- 6; age range, 9 to 30 years) underg...

journal_title：Chest

authors： Ercisli M,Vural KM,Gokkaya KN,Koseoglu F,Tufekcioglu O,Sener E,Tasdemir O

更新日期：2005-08-01 00:00:00

abstract：SETTING:Seven primary health clinics and a pulmonary disease specialty clinic in Rio de Janeiro City, Brazil. OBJECTIVE:To evaluate a commercial immunochromatographic test kit (ICT Tuberculosis; AMRAD-ICT; Sidney, Australia) employing five recombinant Mycobacterium tuberculosis proteins for the detection of pulmonary ...

journal_title：Chest

authors： Perkins MD,Conde MB,Martins M,Kritski AL

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Atrial fibrillation (AF) is associated with a high risk of stroke. The contribution of arrhythmia to events is clear in sustained forms of AF, but in paroxysmal AF, presently available data have yet to identify what proportion of time spent in AF (ie, arrhythmia burden [AFB]) is of clinical relevance. We aim...

journal_title：Chest

authors： Watson T,Arya A,Sulke N,Lip GY

更新日期：2010-04-01 00:00:00

abstract：:Flecainide and propafenone are effective in suppressing both ventricular and supraventricular tachyarrhythmias, but their efficacy is often limited by dose-related side effects. This study was performed to evaluate noninvasively the effects of intravenous flecainide and propafenone on left ventricular systolic functio...

journal_title：Chest

authors： Santinelli V,Arnese M,Oppo I,Matarazzi C,Maione S,Palma M,Giunta A

更新日期：1993-04-01 00:00:00

abstract：:A patient with the sick sinus syndrome accompanying mirror-image dextrocardia which was associated with double superior venae cavae and an absent inferior vena cava is presented. A permanent transvenous demand pacemaker was inserted because of repeated episodes of dizziness and a documented 31/2-second period of asyst...

journal_title：Chest

authors： Goyal SL,Lichestein E,Gupta PK,Chadda KD,Lajam F

更新日期：1976-04-01 00:00:00