Abstract:
STUDY OBJECTIVES:To determine the sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of the dipyridamole stress test (DSST) in predicting > or = 50% obstruction of an internal mammary artery or new native coronary artery disease (CAD) compared with saphenous vein graft obstruction > or = 50% in patients with prior coronary artery surgery and symptoms. DESIGN:In 144 patients with prior coronary artery surgery who underwent a DSST within 8 +/- 7 days of coronary angiography performed because of cardiac symptoms, we investigated the sensitivity, specificity, PPV, and NPV of the DSST in predicting > or = 50% obstruction of an internal mammary artery or new native CAD (201 total arterial conduits) vs > or = 50% obstruction of saphenous vein grafts (total saphenous grafts = 246). SETTING:A university hospital. PATIENTS:The 144 patients included 88 men and 56 women, mean age 68 +/- 9 years (+/- SD). RESULTS:The DSST had a sensitivity of 81%, a specificity of 87%, a PPV of 84%, and a NPV of 84% in predicting > or = 50% obstruction of an internal mammary artery or new native CAD. The DSST had a sensitivity of 88%, a specificity of 82%, a PPV of 86%, and a NPV of 85% in predicting > or = 50% obstruction of saphenous vein grafts. CONCLUSION:There was no significant difference in sensitivity, specificity, PPV, or NPV of the DSST in predicting > or = 50% obstruction of an internal mammary artery or new native CAD vs predicting > or = 50% obstruction of saphenous vein grafts in patients with prior coronary artery surgery and cardiac symptoms.
journal_name
Chestjournal_title
Chestauthors
Deluca AJ,Cusack E,Aronow WS,Monsen CEdoi
10.1378/chest.126.4.1040subject
Has Abstractpub_date
2004-10-01 00:00:00pages
1040-1issue
4eissn
0012-3692issn
1931-3543pii
S0012-3692(15)31274-5journal_volume
126pub_type
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