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A prospective long-term study of 220 patients with a retrievable vena cava filter for secondary prevention of venous thromboembolism.

Abstract：

BACKGROUND:The immediate and long-term clinical events associated with the placement and removal of a retrievable filter (ALN filter; ALN Implants Chirurgicaux; Ghisonaccia, France) remain largely unknown. METHODS:This was a prospective cohort study with an 18-month follow-up. All consecutive patients scheduled for placement of an ALN filter between April 1999 and June 2005 in the Radiology Department of our hospital were included. RESULTS:During the study period, placement of an ALN filter was indicated in 220 patients (mean age, 70.8 years), who were followed up for a median duration of 338.5 days (range, 1 to 561 days); 148 patients (67.3%) completed the 18-month follow-up. No patients were unavailable for follow-up. All patients had an acute or past venous thromboembolism. Main indications were recurrent venous thromboembolism despite adequate anticoagulation therapy (10.9%), transient bleeding event (21.8%), definitive contraindication for anticoagulant therapy (26.8%), or obligation to stop anticoagulant therapy due to major surgery, major trauma, or invasive procedure (37.7%). Filter insertion was successful in 98.6% of patients and resulted in an immediate complication in 11.8%. The median duration of filter implantation was 166 days (first to third quartiles, 34 to 478 days). Meanwhile, 17.0% (37 of 217 patients) had at least one venous thromboembolic event. Filter retrieval was attempted in 25.3% of patients after a median of 51 days (range, 6 to 352 days); removal was successful at the first attempt in 92.7% of patients. CONCLUSIONS:The filter could be easily inserted and successfully removed up to 1 year after insertion. Its safety and efficacy in preventing pulmonary embolism should be properly assessed in a randomized study.

journal_name

Chest

journal_title

Chest

authors

Mismetti P,Rivron-Guillot K,Quenet S,Décousus H,Laporte S,Epinat M,Barral FG

doi

10.1378/chest.06-0631

subject

Has Abstract

pub_date

2007-01-01 00:00:00

pages

223-9

issue

eissn

0012-3692

issn

1931-3543

pii

S0012-3692(15)49904-0

journal_volume

131

pub_type

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A prospective long-term study of 220 patients with a retrievable vena cava filter for secondary prevention of venous thromboembolism.