Air leaks after lobectomy increase the risk of empyema but not of cardiopulmonary complications: a case-matched analysis.

Abstract:

PURPOSE:To assess whether the presence and duration of air leaks after lobectomy are associated with an increased incidence of cardiopulmonary complications. METHODS:Propensity score analysis was used on 726 patients undergoing pulmonary lobectomy from 1995 through 2004 to form three well-matched pairs of patients: patients with prolonged air leak (PAL) [> 7 days] and without air leak; patients with short air leak (SAL) [< or = 7 days] and without air leak; and patients with SAL and PAL. These matched groups were then compared to assess postoperative hospital stay and early outcome. RESULTS:Patients with SAL had a longer postoperative hospital stay compared to patients without air leak (8.6 days vs 7.8 days, respectively; p < 0.0001) but had similar morbidity and mortality. Patients with PAL had a longer postoperative hospital stay compared to patients without air leak (16.2 days vs 8.3 days, respectively; p < 0.0001) and with SAL (16.9 days vs 9 days, respectively; p < 0.0001), but similar cardiopulmonary complications were noted between the groups. Patients with PAL had a higher rate of empyema compared to patients without air leak and with SAL (8.2% vs 0%, p = 0.01 and 10.4% vs.1.1%, p = 0.01, respectively). CONCLUSIONS:The presence of air leak was not associated with an increased incidence of cardiopulmonary morbidity but was associated with an increased risk of empyema. Future prospective studies are needed to confirm safety of fast track in patients with air leak.

journal_name

Chest

journal_title

Chest

authors

Brunelli A,Xiume F,Al Refai M,Salati M,Marasco R,Sabbatini A

doi

10.1378/chest.130.4.1150

subject

Has Abstract

pub_date

2006-10-01 00:00:00

pages

1150-6

issue

4

eissn

0012-3692

issn

1931-3543

pii

S0012-3692(15)51152-5

journal_volume

130

pub_type

杂志文章

相关文献

CHEST文献大全
  • Giant cell carcinoma of the lung. Clinical and roentgenographic manifestations.

    abstract::Giant cell carcinoma of the lung is an unusual form of pulmonary malignancy that follows an extremely aggressive clinical course. We report the clinical and roentgenographic manifestations of 14 patients with pathologically proven giant cell carcinoma of the lung, and compare our data to other reports in the literatur...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.89.3.366

    authors: Shin MS,Jackson LK,Shelton RW Jr,Greene RE

    更新日期:1986-03-01 00:00:00

  • Single-nucleotide polymorphisms and lung disease: clinical implications.

    abstract::Human genetic variation has enormous implications for individual susceptibility to lung disease, as well as for differences in prognosis and response to therapeutic interventions. Single-nucleotide polymorphisms (SNPs) are the most common type of DNA sequence variation. An SNP is the substitution of a single base in t...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.06-2252

    authors: Tebbutt SJ,James A,Paré PD

    更新日期:2007-04-01 00:00:00

  • Cost-effectiveness of fluticasone propionate administered via metered-dose inhaler plus babyhaler spacer in the treatment of asthma in preschool-aged children.

    abstract:STUDY OBJECTIVES:To evaluate the cost-effectiveness of inhaled fluticasone propionate (FP) in children aged 12 to 47 months with asthma symptoms. DESIGN:A retrospective economic analysis conducted from the perspective of the Danish health-care system, based on clinical data from a 12-week study. SETTING:Thirty-three ...

    journal_title:Chest

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1378/chest.120.6.1835

    authors: Bisgaard H,Price MJ,Maden C,Olsen NA

    更新日期:2001-12-01 00:00:00

  • Factors predictive of survival among 337 patients with mesothelioma treated between 1984 and 1994 by the Cancer and Leukemia Group B.

    abstract:PURPOSE:To examine the individual and joint effect of various pretreatment clinical characteristics on the survival of patients with mesothelioma treated by the Cancer and Leukemia Group B (CALGB). PATIENTS AND METHODS:Between June 1984 and September 1994, 337 patients with malignant mesothelioma and no prior chemothe...

    journal_title:Chest

    pub_type: 临床试验,杂志文章

    doi:10.1378/chest.113.3.723

    authors: Herndon JE,Green MR,Chahinian AP,Corson JM,Suzuki Y,Vogelzang NJ

    更新日期:1998-03-01 00:00:00

  • The effect of oxygen with exercise on atrial natriuretic peptide in chronic obstructive lung disease.

    abstract::A recent study on stable, hypoxemic, COLD patients in which ANP was stimulated by LBPP demonstrated that in these individuals elevation of ANP does not exert a "normal" suppressing effect on the PRA-PA axis. Accordingly, we exercised ten comparable COLD patients, another maneuver known to stimulate ANP and to elicit c...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.101.2.341

    authors: Mannix ET,Manfredi F,Palange P,Aronoff GR,Weinberger MH,Farber MO

    更新日期:1992-02-01 00:00:00

  • Gas exchange in chronic thromboembolism after pulmonary thromboendarterectomy.

    abstract::Thromboendarterectomy is the treatment of choice for chronic large vessel thromboembolic pulmonary hypertension. To identify the mechanisms responsible for the improvement in gas exchange following thromboendarterectomy, we studied nine patients with chronic thromboembolic pulmonary hypertension before and eight to 18...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.98.1.14

    authors: Kapitan KS,Clausen JL,Moser KM

    更新日期:1990-07-01 00:00:00

  • Distinct characteristics of pleuroparenchymal fibroelastosis with usual interstitial pneumonia compared with idiopathic pulmonary fibrosis.

    abstract:BACKGROUND:Pleuroparenchymal fibroelastosis (PPFE) is a rare form of interstitial pneumonia and sometimes coexists with a histologic usual interstitial pneumonia (UIP) pattern. This study aimed to describe the distinct clinical features of PPFE with UIP pattern compared with idiopathic pulmonary fibrosis (IPF). METHOD...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.13-2866

    authors: Oda T,Ogura T,Kitamura H,Hagiwara E,Baba T,Enomoto Y,Iwasawa T,Okudela K,Takemura T,Sakai F,Hasegawa Y

    更新日期:2014-11-01 00:00:00

  • Negative pressure pulmonary edema following bronchospasm.

    abstract::Negative pressure pulmonary edema (NPPE) is an important cause of noncardiogenic pulmonary edema but is rarely reported in the setting of bronchospasm. A 43-year-old woman with severe reactive airway disease suffered an episode of severe bronchospasm after endotracheal extubation following an otherwise uneventful gene...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.11-0529

    authors: Krodel DJ,Bittner EA,Abdulnour RE,Brown RH,Eikermann M

    更新日期:2011-11-01 00:00:00

  • Sleepiness and hypertension in obstructive sleep apnea.

    abstract::In order to assess the complications of sleep apnea, we have reviewed a data base of 619 consecutive admissions to a university sleep disorders center. Although patients with obstructive sleep apnea (OSA) described more subjective sleepiness than patients with central sleep apnea (CSA) or primary snoring (PS), the mul...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.101.4.903

    authors: Mendelson WB

    更新日期:1992-04-01 00:00:00

  • Structural changes in airway diseases: characteristics, mechanisms, consequences, and pharmacologic modulation.

    abstract::In airway diseases such as asthma and COPD, specific structural changes may be observed, very likely secondary to an underlying inflammatory process. Although it is still controversial, airway remodeling may contribute to the development of these diseases and to their clinical expression and outcome. Airway remodeling...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.129.4.1068

    authors: Bergeron C,Boulet LP

    更新日期:2006-04-01 00:00:00

  • Effect of inhaled norepinephrine on the nitroglycerin-induced bronchodilatation in asthmatics.

    abstract::Previous studies on the bronchodilating effect of nitrates yielded conflicting results. We hypothesized that the concomitant bronchial vasodilatation induced by nitrates may limit the increase of airway patency due to bronchial smooth muscle relaxation. To test this hypothesis, we evaluated the bronchodilating effect ...

    journal_title:Chest

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1378/chest.107.1.169

    authors: Rolla G,Bucca C,Brussino L

    更新日期:1995-01-01 00:00:00

  • Health-care costs and exercise capacity.

    abstract:BACKGROUND:While the beneficial effect of exercise capacity on mortality is well-accepted, its effect on health-care costs remains uncertain. This study investigates the relationship between exercise capacity and health-care costs. METHODS:The Veterans Affairs Health Care System recently implemented a Decision Support...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.126.2.608

    authors: Weiss JP,Froelicher VF,Myers JN,Heidenreich PA

    更新日期:2004-08-01 00:00:00

  • Usual interstitial pneumonia associated with primary Sjögren's syndrome.

    abstract::We describe the first case, to our knowledge, of usual interstitial pneumonia (UIP) as the pulmonary manifestation in primary Sjögren's syndrome (SjS). A 45-year-old woman was admitted to our hospital because of a dry cough and an interstitial shadow on a chest roentgenogram. Labial biopsy and sialogram confirmed a di...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.108.6.1756

    authors: Kadota J,Kusano S,Kawakami K,Morikawa T,Kohno S

    更新日期:1995-12-01 00:00:00

  • Pleural effusion in patients with systemic cholesterol embolization.

    abstract::We evaluated two patients with systemic cholesterol embolization (SCE) associated with the development of pleural effusions. These two patients had evidence of atherosclerosis and presented with livedo reticularis, renal insufficiency, and gangrenous cutaneous changes as manifestations of their SCE. In both cases, clo...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.103.3.792

    authors: Kollef MH,McCormack MT,Kristo DA,Reddy VV

    更新日期:1993-03-01 00:00:00

  • Growth hormone response to growth hormone-releasing hormone is reduced in adult asthmatic patients receiving long-term inhaled corticosteroid treatment.

    abstract:BACKGROUND:Some studies have demonstrated that the function of the growth hormone (GH)-insulin-like growth factor (IGF)-1 axis is significantly impaired in patients with oral corticosteroid (CS)-induced osteoporosis. The aim of study was to investigate the effects of long-term therapy with inhaled CSs (ICSs) on the hyp...

    journal_title:Chest

    pub_type: 临床试验,杂志文章

    doi:10.1378/chest.127.2.515

    authors: Malerba M,Bossoni S,Radaeli A,Mori E,Bonadonna S,Giustina A,Tantucci C

    更新日期:2005-02-01 00:00:00

  • Fortuitous esophageal intubation.

    abstract::Esophageal malposition is a potentially disastrous complication of attempted airway intubation. We report an unusual case in which a promptly recognized esophageal intubation aided detection of a perforated gastric ulcer. After the endotracheal tube was repositioned and the ulcer was surgically repaired, our patient h...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.103.2.625

    authors: Dunham D,Schmidt GA

    更新日期:1993-02-01 00:00:00

  • Epidemiology and ethnic distribution of multidrug-resistant tuberculosis in southern Israel, 1992-1997: the impact of immigration.

    abstract:STUDY OBJECTIVES:To assess the incidence of tuberculosis in the native and immigrant populations of southern Israel in the period between 1992 and 1997, and to study the prevalence of drug resistance overall and among these subpopulations in the region in order to create guidelines for empirical antituberculous treatme...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.117.3.738

    authors: Gilad J,Borer A,Riesenberg K,Peled N,Schlaeffer F

    更新日期:2000-03-01 00:00:00

  • Esophageal-directed pressure support ventilation in normal volunteers.

    abstract:STUDY OBJECTIVES:To ascertain whether inspiratory pressure support (IPS) can be triggered reliably from and targeted at esophageal pressures (Pes), and to compare the work of breathing and time delay to initiation of inspiratory flow between conventional pressure support and esophageal-directed pressure support (EDPS)....

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.115.2.482

    authors: Barnard M,Shukla A,Lovell T,Goldstone J

    更新日期:1999-02-01 00:00:00

  • The Master Settlement Agreement and its impact on tobacco use 10 years later: lessons for physicians about health policy making.

    abstract::The issue of tobacco industry responsibility for population health problems and compensation for their treatment has been growing since the 1960s. In 1999, the state attorneys general collectively launched the largest class action lawsuit in US history and sued the tobacco industry to recover the costs of caring for s...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.09-0982

    authors: Jones WJ,Silvestri GA

    更新日期:2010-03-01 00:00:00

  • Does oximetry contribute to the detection of apneic events? Mathematical processing of the SaO2 signal.

    abstract::The purpose of this study was to assess the ability of continuous nocturnal oximetry to detect sleep apnea syndrome (SAS) and to recognize nonapneic oxyhemoglobin desaturations. Oxygen saturation oscillations, related to successive apneas in SAS or to apneic episodes in COPD or restrictive patients, were quantified us...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.99.5.1151

    authors: Pépin JL,Lévy P,Lepaulle B,Brambilla C,Guilleminault C

    更新日期:1991-05-01 00:00:00

  • Left ventricular function in myocardial infarction. Predictive value during negative low-level exercise three weeks postinfarction.

    abstract::To evaluate whether the response of left ventricular pump function during low-level exercise in the early postinfarction period can anticipate its change during the first year after acute myocardial infarction (MI), global and regional ejection fractions (EF) were investigated using radionuclide angiography in 52 cons...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.102.2.335

    authors: Iwasaka T,Sugiura T,Nakamura S,Okubo N,Inada M

    更新日期:1992-08-01 00:00:00

  • Multicentric endobronchial granular cell myoblastoma.

    abstract::Granular cell myoblastoma (GCM) is a rare benign neoplasm involving the tracheobronchial tree. It is believed to arise from the Schwann cell. Four cases of tracheobronchial GCM, all of which were multicentric, are presented and a conservative therapeutic approach is suggested. ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.98.4.945

    authors: Redjaee B,Rohatgi PK,Herman MA

    更新日期:1990-10-01 00:00:00

  • A prospective study of community-acquired pneumonia in Hong Kong.

    abstract::A prospective study of community-acquired pneumonia in Hong Kong was carried out between January and December, 1988. Ninety adults (57 male) with a mean age of 57.3 years were admitted to the Prince of Wales Hospital with community-acquired pneumonia. The etiologic diagnosis of pneumonia was made in 37 cases (41 perce...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.101.2.442

    authors: Chan CH,Cohen M,Pang J

    更新日期:1992-02-01 00:00:00

  • Hemodynamic and metabolic effects of rapid correction of hypophosphatemia in patients with septic shock.

    abstract:STUDY OBJECTIVE:To examine the hemodynamic and metabolic short-term effects of hypophosphatemia correction in patients with septic shock receiving catecholamine therapy. DESIGN:Prospective, single cohort study. SETTING:ICU, university hospital. PATIENTS:Ten patients with septic shock and hypophosphatemia below 2 mg/...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.107.6.1698

    authors: Bollaert PE,Levy B,Nace L,Laterre PF,Larcan A

    更新日期:1995-06-01 00:00:00

  • Efficacy of tracheal and bronchial stent placement on respiratory functional tests.

    abstract::Stent placement is the only available treatment in patients presenting either a localized external compression or a malacia of the tracheobronchial tree. To assess the functional benefit of prosthesis insertion in these indications, we compared functional respiratory values before, immediately after (48 h), and at som...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.107.3.741

    authors: Vergnon JM,Costes F,Bayon MC,Emonot A

    更新日期:1995-03-01 00:00:00

  • Surgically curable peripheral lung carcinoma: correlation of thin-section CT findings with histologic prognostic factors and survival.

    abstract:STUDY OBJECTIVES:To define characteristics of surgically curable, early cancers of the lung, we retrospectively studied relationships between thin-section CT (TS-CT) scans, pathologic features, and outcome data in 287 patients with resected small-diameter (< 20 mm) peripheral lung carcinoma. Cases included 260 adenocar...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.127.3.871

    authors: Shimizu K,Yamada K,Saito H,Noda K,Nakayama H,Kameda Y,Nakata K

    更新日期:2005-03-01 00:00:00

  • A prospective study of the safety of tracheal extubation using a pediatric airway exchange catheter for patients with a known difficult airway.

    abstract:STUDY OBJECTIVE:To determine the usefulness of routinely inserting a hollow airway exchange catheter (jet stylet) prior to tracheal extubation of adult patients with risk factors for difficult tracheal intubation. DESIGN:Prospective, 1-year study of 40 consecutive patients undergoing mechanical ventilation who had one...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.111.6.1660

    authors: Loudermilk EP,Hartmannsgruber M,Stoltzfus DP,Langevin PB

    更新日期:1997-06-01 00:00:00

  • A new diagnostic score for occupational asthma: the area between the curves (ABC score) of peak expiratory flow on days at and away from work.

    abstract:BACKGROUND:Evidence-based guidelines recommend serial measurements of peak expiratory flow (PEF) on days at and away from work as the first step in the objective confirmation of occupational asthma. The aim of this study was to improve the diagnostic value of computer-based PEF analysis by using the program Oasys-2 to ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.08-0778

    authors: Moore VC,Jaakkola MS,Burge CBSG,Robertson AS,Pantin CFA,Dev Vellore A,Burge PS

    更新日期:2009-02-01 00:00:00

  • Relationship of oxygen consumption and oxygen delivery in surgical patients with ARDS.

    abstract::Previous studies have described oxygen delivery (DO2) and oxygen consumption (VO2) relationships in patients with ARDS and other acute diseases that suggest occasions when VO2 may be dependent on the supply of oxygen, ie, DO2. We studied 127 postoperative patients who developed ARDS to evaluate the relationship of DO2...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.102.3.906

    authors: Appel PL,Shoemaker WC

    更新日期:1992-09-01 00:00:00

  • Sympathetic nervous system alterations in sleep apnea. The relative importance of respiratory disturbance, hypoxia, and sleep quality.

    abstract::Numerous alterations in the sympathetic nervous system have been reported in patients with obstructive sleep apnea. It is unclear whether such alterations can be attributed to the respiratory disturbance itself, the resulting hypoxia, or disruption of sleep. We examined urinary norepinephrine levels in 45 individuals ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.111.3.639

    authors: Dimsdale JE,Coy T,Ancoli-Israel S,Mills P,Clausen J,Ziegler MG

    更新日期:1997-03-01 00:00:00