Elevated levels of the receptor for advanced glycation end products, a marker of alveolar epithelial type I cell injury, predict impaired alveolar fluid clearance in isolated perfused human lungs.

abstract：:Low-dose dopamine administration (ie, doses < 5 microg/kg/min) has been advocated for 30 years as therapy in oliguric patients on the basis of its action on dopaminergic renal receptors. Recently, a large, multicenter, randomized, controlled trial has demonstrated that low-dose dopamine administered to critically ill ...

journal_title：Chest

authors： Holmes CL,Walley KR

更新日期：2003-04-01 00:00:00

abstract：:We present a case in which the radiographic appearance of a bipolar pacing lead mimics a wire fracture. Recognition of this normal finding--due to lead construction--will help avoid erroneous diagnosis of wire fracture on chest x-ray films. ...

journal_title：Chest

authors： Hecht S,Berdoff R,Van Tosh A,Goldberg E

更新日期：1985-08-01 00:00:00

abstract：BACKGROUND:The effects of regular inhaled beta-agonist treatment on lung function remain a controversial issue. In an earlier study, the administration of regular inhaled salbutamol resulted in negative changes in FEV1 not only in asthmatics, but also in nonasthmatic atopic subjects. OBJECTIVE:The aim of this study wa...

journal_title：Chest

authors： Boothman-Burrell D,Jones D,Herbison GP,Taylor DR

更新日期：1997-07-01 00:00:00

abstract：STUDY OBJECTIVES:Sputum induction (SI) is a noninvasive tool for sampling inflamed airways. The purpose of this study was to determine the optimal duration of collection in patients with cystic fibrosis (CF). The hypothesis was that the duration of SI collection would quantitatively and qualitatively alter the content ...

journal_title：Chest

authors： Aitken ML,Greene KE,Tonelli MR,Burns JL,Emerson JC,Goss CH,Gibson RL

更新日期：2003-03-01 00:00:00

abstract：:In patients with chronic obstructive pulmonary disease (COPD) studied at rest, nifedipine releases hypoxic pulmonary vasoconstriction (HPV) and worsens gas exchange. During exercise, this drug lowers pulmonary hypertension, but the effects of this lower pulmonary vascular tone on ventilation-perfusion (VA/Q) relations...

journal_title：Chest

authors： Agustí AG,Barberá JA,Roca J,Wagner PD,Guitart R,Rodriguez-Roisín R

更新日期：1990-02-01 00:00:00

abstract：STUDY OBJECTIVE:The purpose of this study was to evaluate the diagnostic value of low voltage with PR-segment and ST-T wave changes in determining the amount of clinically silent pericardial effusion detected in a routine echocardiography. DESIGN:Consecutive case series analysis. SETTING:Noninvasive cardiology depart...

journal_title：Chest

authors： Kudo Y,Yamasaki F,Doi T,Doi Y,Sugiura T

更新日期：2003-12-01 00:00:00

abstract：STUDY OBJECTIVES:We report on the long-term safety and efficacy of bosentan treatment in patients with pulmonary arterial hypertension (PAH). BACKGROUND:In a preceding study, bosentan was well tolerated and significantly improved the exercise capacity and hemodynamics of patients with PAH after 12 weeks of treatment. ...

journal_title：Chest

authors： Sitbon O,Badesch DB,Channick RN,Frost A,Robbins IM,Simonneau G,Tapson VF,Rubin LJ

更新日期：2003-07-01 00:00:00

abstract：:We performed autonomic function testing in 68 patients, 34 with diabetes mellitus (group A) and 34 without (group B), at 72 h after a first acute myocardial infarction (MI) to determine the prevalence of autonomic dysfunction in these patients. Heart rate (HR) variation during 6 breaths/min obtained from mean of longe...

journal_title：Chest

authors： Bhatnagar SK,Al-Yusuf AR,Al-Asfoor AR

更新日期：1987-11-01 00:00:00

abstract：:The need for fiberoptic bronchoscopy in the patient with hemoptysis and a normal or nonlocalizing chest roentgenogram remains a subject of debate. Currently, diagnostic fiberoptic bronchoscopy is recommended as the investigative procedure of choice. To develop predictors that identify the patient in whom fiberoptic br...

journal_title：Chest

authors： Poe RH,Israel RH,Marin MG,Ortiz CR,Dale RC,Wahl GW,Kallay MC,Greenblatt DG

更新日期：1988-01-01 00:00:00

abstract：:As an aid in the differential diagnosis of exudative pleural effusions, tumor markers were investigated. We measured immunosuppressive acidic protein (IAP), carbohydrate antigen 19-9 (CA 19-9), tissue polypeptide antigen (TPA), carcinoembryonic antigen (CEA), adenosine deaminase (ADA), and alpha 1-acid glycoprotein (A...

journal_title：Chest

authors： Niwa Y,Kishimoto H,Shimokata K

更新日期：1985-03-01 00:00:00

abstract：:Exertional dyspnea is a common complaint for patients seen in pulmonary, cardiac, and general medicine clinics, and elucidating the cause is often challenging, particularly when physical examination, echocardiography, radiography, and pulmonary function test results are inconclusive. Invasive cardiopulmonary exercise ...

journal_title：Chest

authors： Jain CC,Borlaug BA

更新日期：2020-11-01 00:00:00

abstract：:Exacerbations of sarcoidosis are common. In particular, exacerbations of pulmonary sarcoidosis are reported in more than one-third of patients. Despite their frequent occurrence, there is little medical evidence concerning the definition, diagnosis, and treatment of pulmonary exacerbations of sarcoidosis. In this arti...

journal_title：Chest

authors： Panselinas E,Judson MA

更新日期：2012-10-01 00:00:00

abstract：:Disappointing results of surgery and postoperative adjuvant chemotherapy or chemoradiotherapy in stage IIIA (N2) lung cancer have led to a number of phase II trials of induction (neoadjuvant) chemotherapy given prior to surgery. Preliminary results of 2 such studies indicate that mitomycin, vinca alkaloid, and platinu...

journal_title：Chest

authors： Ginsberg RJ

更新日期：1993-04-01 00:00:00

abstract：:Serum levels of a high molecular weight circulating antigen KL-6, detected by means of a sandwich assay using a monoclonal antibody KL-6 against a sialylated carbohydrate antigen, were evaluated for usefulness in monitoring the activity of interstitial pneumonitis. Abnormally high levels of KL-6 antigen were observed ...

journal_title：Chest

authors： Kohno N,Kyoizumi S,Awaya Y,Fukuhara H,Yamakido M,Akiyama M

更新日期：1989-07-01 00:00:00

abstract：:Endobronchial ultrasonography (EBUS) has become an invaluable tool in the diagnosis of patients with a variety of thoracic abnormalities. The majority of EBUS procedures are used to diagnose and stage mediastinal and hilar abnormalities, as well as peripheral pulmonary targets, with a probe-based technology. Nearly 1,...

journal_title：Chest

authors： Gildea TR,Nicolacakis K

更新日期：2016-12-01 00:00:00

abstract：:It has been observed that T-lymphocytes of patients with tuberculosis produce interferon gamma (IFN gamma) in vitro. Based on this idea, we studied IFN gamma in pleural fluid and serum. We studied 80 patients with pleural effusion; 30 patients with tuberculous pleurisy had high IFN gamma concentrations in pleural flui...

journal_title：Chest

authors： Ribera E,Ocaña I,Martinez-Vazquez JM,Rossell M,Español T,Ruibal A

更新日期：1988-02-01 00:00:00

abstract：BACKGROUND:Chronic rhinosinusitis (CRS) has been reported to be associated with increased values of exhaled nitric oxide (ENO), which could not be entirely explained by the association between CRS and asthma. The aim of this study was to investigate the variables associated with increased ENO in patients with CRS. MET...

journal_title：Chest

authors： Guida G,Rolla G,Badiu I,Marsico P,Pizzimenti S,Bommarito L,De Stefani A,Usai A,Bugiani M,Malinovschi A,Bucca C,Heffler E

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:In recent years, the population of patients with pulmonary arterial hypertension (PAH) has changed dramatically, including more advanced age at diagnosis. We hypothesized that older patients have a distinct clinical profile with different disease characteristics and response to intervention. METHODS:All pre...

journal_title：Chest

authors： Rose JA,Cleveland JM,Rao Y,Minai OA,Tonelli AR

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:The leading cause of pericardial effusion in urban hospitals is now AIDS-related pathologies. Clinically, these effusions are a diagnostic and management dilemma. In our institution, pericardial biopsy and operative drainage have become part of the diagnostic and management plan. Surgical intervention, howev...

journal_title：Chest

authors： Flum DR,McGinn JT Jr,Tyras DH

更新日期：1995-06-01 00:00:00

abstract：:On the occasion of this Fourth World Conference on Lung Cancer, I am privileged to present the opening keynote address. This presentation has been sponsored by the Ontario Cancer Treatment and Research Foundation. In 1952, the Foundation established an annual lectureship in memory of one of their prominent physicians....

journal_title：Chest

authors： Pearson FG

更新日期：1986-04-01 00:00:00

abstract：:A 54-year-old Japanese man demonstrated a sultamicillin-induced hilar and mediastinal lymphadenopathy with hypersensitivity pneumonitis. A positive lymphocyte stimulation test for sultamicillin and a decreased CD4/CD8 ratio of lymphocytes in BAL fluid suggested that an alteration in cell-mediated mechanisms was respon...

journal_title：Chest

authors： Yonemaru M,Mizuguchi Y,Kasuga I,Utsumi K,Ichinose Y,Toyama K

更新日期：1992-12-01 00:00:00

abstract：OBJECTIVES:This multicenter, double-blind, placebo-controlled study evaluated the dose response to 6 weeks of triamcinolone acetonide inhalation aerosol (TAA, 100 microg per puff) in patients with moderately severe asthma. STUDY DESIGN:A total of 285 patients were randomly assigned to treatment with 1, 2, 4, or 8 puff...

journal_title：Chest

authors： Welch MJ,Levy S,Smith JA,Feiss G,Farrar JR

更新日期：1997-09-01 00:00:00

abstract：:A patient complained of angina pectoris nine months after surgical repair of an aortic right atrial fistula and mitral valve replacement. Subsequently, he was shown to have a new obstruction of the ostium of the left main coronary artery. This case illustrates the need to consider this syndrome in the differential dia...

journal_title：Chest

authors： Coplan NL,Estioko MR,Ambrose JA

更新日期：1985-09-01 00:00:00

abstract：BACKGROUND:Pulse pressure (PP) has been shown to predict risk for cardiovascular events in men; however, this association has not been well established in women. Hormone replacement therapy may improve arterial compliance, but findings from cross-sectional and prospective studies report inconsistent results. We sought ...

journal_title：Chest

authors： Nair GV,Chaput LA,Vittinghoff E,Herrington DM,Heart and Estrogen\/Progestin Replacement Study Investigators.

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:Pulmonary vascular capacitance (PVC) is reduced in pulmonary arterial hypertension (PAH). In normal lung, PVC is largely a function of vascular compliance. In PAH, increased pulmonary vascular resistance (PVR) arises from the arterioles. PVR and PVC share pressure and volume variables. The dependency between...

journal_title：Chest

authors： Newman JH,Brittain EL,Robbins IM,Hemnes AR

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:Disease-specific patient-reported outcome (PRO) instruments are important in assessing the impact of disease and treatment. The Pulmonary Arterial Hypertension-Symptoms and Impact Questionnaire is the first instrument for quantifying pulmonary arterial hypertension (PAH) symptoms and impacts developed accord...

journal_title：Chest

authors： Chin KM,Gomberg-Maitland M,Channick RN,Cuttica MJ,Fischer A,Frantz RP,Hunsche E,Kleinman L,McConnell JW,McLaughlin VV,Miller CE,Zamanian RT,Zastrow MS,Badesch DB

更新日期：2018-10-01 00:00:00

abstract：STUDY OBJECTIVES:Biochemical and inflammatory markers in pleural inflammation were evaluated in pediatric cases of parapneumonic effusions, and interleukin (IL)-8 and tumor necrosis factor (TNF)-alpha concentrations were tested for possible differentiation of the complicated nature of effusions. PATIENTS:Twenty-eight ...

journal_title：Chest

authors： Utine GE,Ozcelik U,Yalcin E,Dogru D,Kiper N,Aslan A,Kanra G

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:Heparin-induced thrombocytopenia (HIT) is an antibody-mediated adverse drug reaction that can lead to devastating thromboembolic complications, including pulmonary embolism, ischemic limb necrosis necessitating limb amputation, acute myocardial infarction, and stroke. METHODS:The methods of this guideline f...

journal_title：Chest

authors： Linkins LA,Dans AL,Moores LK,Bona R,Davidson BL,Schulman S,Crowther M

更新日期：2012-02-01 00:00:00

abstract：:This study addresses the hypothesis that patients with obstructive sleep apnea, who exhibit recurrent episodes of oxygen desaturation at night, have higher hematocrit levels than nonapneic control subjects. We prospectively studied 624 patients referred to the sleep disorders center at St. Michael's Hospital because o...

journal_title：Chest

authors： Hoffstein V,Herridge M,Mateika S,Redline S,Strohl KP

更新日期：1994-09-01 00:00:00

abstract：:Persistent minor hemoptysis resulted from extensive granulation tissue on the main carina and adjacent bronchi due to frequent spraying of metered-dose inhaler (MDI)-generated aerosol medications directly into a permanent tracheostomy. Salbutamol, containing oleic acid, was considered the most likely cause. After an A...

journal_title：Chest

authors： Newhouse MT

更新日期：1999-01-01 00:00:00