Effects of the dual endothelin receptor antagonist bosentan in patients with pulmonary arterial hypertension: a 1-year follow-up study.

abstract：:Ten patients who take hydroxy-methylglutaryl coenzyme A reductase inhibitors, or statin medications, and experience adverse reactions are described. All patients experienced various manifestations of hypersensitivity while receiving the drugs. One patient is described with hypersensitivity pneumonitis, which was graph...

journal_title：Chest

authors： Liebhaber MI,Wright RS,Gelberg HJ,Dyer Z,Kupperman JL

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND:Inadequate localized drug concentrations and systemic adverse effects are among the concerns when regional infections are treated with systemic antibiotics. We designed and fabricated a poly(D,L)-lactide-co-glycolide (PLGA)-based biodegradable drug delivery system and evaluated the release of antibiotics bot...

journal_title：Chest

authors： Liu KS,Liu SJ,Chen HY,Huang YK,Peng YJ,Wu RC,Ueng SW

更新日期：2012-05-01 00:00:00

abstract：:Cardiovascular complications from cocaine use have been recognized in increasing frequency in recent years. We report the case of a young man with a history of intranasal cocaine use presenting with acute congestive heart failure who, on postmortem examination, was found to have idiopathic hemochromatosis. It is specu...

journal_title：Chest

authors： Goldenberg SP,Zeldis SM

更新日期：1987-08-01 00:00:00

abstract：BACKGROUND:Prostasin, a trypsin-like serine protease, is a channel-activating protease and major regulator of epithelial sodium channel-mediated sodium absorption. Its direct inhibition by camostat represents a potential approach to inhibiting sodium transport in cystic fibrosis (CF). METHODS:To determine whether a to...

journal_title：Chest

authors： Rowe SM,Reeves G,Hathorne H,Solomon GM,Abbi S,Renard D,Lock R,Zhou P,Danahay H,Clancy JP,Waltz DA

更新日期：2013-07-01 00:00:00

abstract：:A case is presented of a reversible intra-Hisian block occurring under amiodarone treatment for atrial tachycardia in a patient without clear intraventricular conduction abnormalities. His bundle recordings showed an atrial tachycardia with intermittent exit block and greatly prolonged BH and HV intervals (40 and 100 ...

journal_title：Chest

authors： Santinelli V,Chiariello M,Ambrosio G,Stanislao M,Condorelli M

更新日期：1982-07-01 00:00:00

abstract：:Because of an emphasis on patient safety and recognition of the effectiveness of simulation as an educational modality across multiple medical specialties, use of health-care simulation (HCS) for medical education has become more prevalent. In this article, the effectiveness of simulation for areas important to the pr...

journal_title：Chest

authors： Seam N,Lee AJ,Vennero M,Emlet L

更新日期：2019-12-01 00:00:00

abstract：STUDY OBJECTIVES:To determine patterns in asbestos-induced lung diseases found in older, less exposed workers. DESIGN:Review of a database evaluating lung function, smoking status, form of asbestos-induced lung disease, and radiograph abnormalities. SETTING:Outpatient clinic. PARTICIPANTS:A total of 3383 asbestos-ex...

journal_title：Chest

authors： Ohar J,Sterling DA,Bleecker E,Donohue J

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND:Acute care nurse practitioners (ACNPs) are increasingly being employed in ICUs to offset physician shortages, but no data exist about outcomes of critically ill patients continuously cared for by ACNPs. METHODS:Prospective cohort study of all admissions to an adult medical ICU in an academic, tertiary-care ...

journal_title：Chest

authors： Landsperger JS,Semler MW,Wang L,Byrne DW,Wheeler AP

更新日期：2016-05-01 00:00:00

abstract：:Chronic thromboembolic pulmonary hypertension (CT-E PH) is a rare and aberrant outcome of acute pulmonary embolism. Because it has become a potentially curable form of pulmonary hypertension, the frequency of recognized cases has increased. We report a case series of 72 patients with CT-E PH evaluated in our instituti...

journal_title：Chest

authors： Simonneau G,Azarian R,Brenot F,Dartevelle PG,Musset D,Duroux P

更新日期：1995-01-01 00:00:00

abstract：STUDY OBJECTIVES:Preoperative renal dysfunction is a risk factor for adverse events in cardiac surgery. This study compared creatinine clearance (ClCr), estimated from the Cockroft and Gault formula, and plasma creatinine level as predictors of outcome after cardiac surgery. DESIGN:Prospective, observational. SETTING...

journal_title：Chest

authors： Wang F,Dupuis JY,Nathan H,Williams K

更新日期：2003-11-01 00:00:00

abstract：:A 72-year-old physician with myeloid metaplasia developed marked thrombocytosis, pulmonary hypertension, and right heart failure following splenectomy. No cause for the pulmonary hypertension could be found. The pulmonary hypertension and right heart failure returned to normal when hydroxyurea therapy corrected the th...

journal_title：Chest

authors： Marvin KS,Spellberg RD

更新日期：1993-02-01 00:00:00

abstract：:A patient underwent exercise testing during evaluation for unexplained dyspnea. Evidence of ventilation-perfusion mismatch was noted and subsequent testing revealed multiple pulmonary emboli. Ventilation perfusion parameters by serial exercise testing progressively improved during the course of the patient's illness b...

journal_title：Chest

authors： Helmers RA,Zavala DC

更新日期：1988-09-01 00:00:00

abstract：STUDY OBJECTIVE:We have previously investigated the effects of microphone type and coupler air chamber depth on lung sound characteristics. We now report the results of experiments exploring the effects of air chamber width, shape, and venting on lung sounds. DESIGN:We used a single electret microphone with a variety ...

journal_title：Chest

authors： Kraman SS,Wodicka GR,Oh Y,Pasterkamp H

更新日期：1995-10-01 00:00:00

abstract：:A smoker presented with pleuritic chest pain and was found to have reticulonodular interstitial opacities on chest x-ray film. Open lung biopsy revealed changes consistent with histiocytosis X, a disease seen almost exclusively in smokers. Smoking cessation was recommended, and the patient complied. A chest x-ray film...

journal_title：Chest

authors： Von Essen S,West W,Sitorius M,Rennard SI

更新日期：1990-09-01 00:00:00

abstract：:An asymptomatic cremator was found incidentally to have lymphocytic alveolitis by bronchoalveolar lavage, and the basis for this finding was investigated. No known causes of lymphocyte alveolitis including sarcoidosis, hypersensitivity pneumonitis, berylliosis, tuberculosis, or fungal diseases of the lung were found. ...

journal_title：Chest

authors： Schauble TL,Rich EA

更新日期：1994-02-01 00:00:00

abstract：BACKGROUND:Adjunctive strategies are an important part of the management of ARDS. However, their application in clinical practice remains inconsistent. RESEARCH QUESTION:We wished to determine the frequency and patterns of use of adjunctive strategies in patients with moderate to severe ARDS (Pao2/Fio2 [P/F ratio] < 1...

journal_title：Chest

authors： Duggal A,Rezoagli E,Pham T,McNicholas BA,Fan E,Bellani G,Rubenfeld G,Pesenti AM,Laffey JG,LUNG SAFE Investigators and the ESICM Trials Group.

更新日期：2020-06-01 00:00:00

abstract：:Sixty-eight patients with tricuspid atresia were seen at Indiana University during the past 30 years. Long term survivors treated without operation emerged from our review. In these, there was a combination of tricuspid atresia and transposition of the great vessels. ...

journal_title：Chest

authors： Shariatzadeh AN,King H,Girod D,Shumacker HB

更新日期：1977-04-01 00:00:00

abstract：:A 75-year-old man with a history of resected colon carcinoma presented to his primary care physician because of a new onset of coughing. The patient had expectorated a small piece of solid tissue; pathologic examination of the tissue found it to be consistent with metastatic colon adenocarcinoma. After further work-up...

journal_title：Chest

authors： Zias EA,Owen RP,Borczuk A,Reichel J,Frater RW

更新日期：1998-01-01 00:00:00

abstract：:Human genetic variation has enormous implications for individual susceptibility to lung disease, as well as for differences in prognosis and response to therapeutic interventions. Single-nucleotide polymorphisms (SNPs) are the most common type of DNA sequence variation. An SNP is the substitution of a single base in t...

journal_title：Chest

authors： Tebbutt SJ,James A,Paré PD

更新日期：2007-04-01 00:00:00

abstract：:The neural mechanisms accompanying dynamic exercise of different intensities were analyzed in dogs and human subjects by means of autoregressive spectral analysis of heart period and arterial pressure variabilities. In the animal experiments, 8 conscious dogs were examined after implanting a solid state pressure gauge...

journal_title：Chest

authors： Rimoldi O,Furlan R,Pagani MR,Piazza S,Guazzi M,Pagani M,Malliani A

更新日期：1992-05-01 00:00:00

abstract：:Breathing against positive expiratory pressure has been used to improve gas exchange in many forms of pulmonary edema, and forced expiration against resistance during exercise has been advocated for climbing at high altitude as a method to optimize performance. To evaluate the effect of expiratory positive airway pres...

journal_title：Chest

authors： Schoene RB,Roach RC,Hackett PH,Harrison G,Mills WJ Jr

更新日期：1985-03-01 00:00:00

abstract：:The effects of filtration and concentration on the cellular and protein composition of bronchoalveolar lavage fluids were examined in ten normal subjects and 11 patients with asthma. Filtration of lavage fluid preferentially removed bronchial epithelial cells, resulting in a relative increase in the proportion of alve...

journal_title：Chest

authors： Lam S,LeRiche JC,Kijek K

更新日期：1985-06-01 00:00:00

abstract：STUDY OBJECTIVE:To ascertain the incidence, types, morbidity, and mortality of infectious episodes in isolated lung transplant recipients. DESIGN:Retrospective chart review of patients who have undergone transplants over a six-year period in one institution. PATIENTS:Twenty-three single and 17 double lung transplants...

journal_title：Chest

authors： Maurer JR,Tullis DE,Grossman RF,Vellend H,Winton TL,Patterson GA

更新日期：1992-04-01 00:00:00

abstract：:This chapter about the recognition, treatment, and prevention of heparin-induced thrombocytopenia (HIT) is part of the Antithrombotic and Thrombolytic Therapy: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Grade 1 recommendations are strong and indicate that the benefi...

journal_title：Chest

authors： Warkentin TE,Greinacher A,Koster A,Lincoff AM

更新日期：2008-06-01 00:00:00

abstract：STUDY OBJECTIVE:To evaluate the role of microaspiration in gastroesophageal reflux-induced bronchoconstriction. DESIGN:Prospective study blinded to the subject. SETTING:Outpatient laboratory of a 908-bed university hospital. PARTICIPANTS:Thirty nonsmoking adults divided into two groups: asthmatics with reflux (AR), ...

journal_title：Chest

authors： Harding SM,Schan CA,Guzzo MR,Alexander RW,Bradley LA,Richter JE

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND:Previous studies on pulmonary hypertension (PH) in systemic sclerosis and related disorders used differing patient populations, and defined PH according to different criteria. We have attempted to determine the prevalence and cause of PH in these disorders using a mainly noninvasive cardiopulmonary evaluatio...

journal_title：Chest

authors： Murata I,Takenaka K,Yoshinoya S,Kikuchi K,Kiuchi T,Tanigawa T,Ito K

更新日期：1997-01-01 00:00:00

abstract：STUDY OBJECTIVES:To determine whether African-American race is independently associated with lung disease in scleroderma. DESIGN:Retrospective review. SETTING:University medical center in Baltimore. PATIENTS:One hundred one patients with diffuse cutaneous scleroderma with available serum samples. MEASUREMENTS:Patie...

journal_title：Chest

authors： Greidinger EL,Flaherty KT,White B,Rosen A,Wigley FM,Wise RA

更新日期：1998-09-01 00:00:00

abstract：:Several reports have implicated pregnancy as a cause of deterioration in patients with pulmonary arteriovenous fistulas. We report a 27-year-old woman with multiple pulmonary arteriovenous fistulas who required coil spring embolotherapy in her 24th week of pregnancy due to a spontaneous hemothorax and hypoxemia. ...

journal_title：Chest

authors： Gammon RB,Miksa AK,Keller FS

更新日期：1990-12-01 00:00:00

abstract：BACKGROUND:Club cell secretory protein (CCSP) is a protective biomarker associated with annual decline in lung function. COPD progression results from an imbalance between injury and repair initially triggered by cigarette smoking. OBJECTIVE:We investigated the effect of CCSP as a therapeutic strategy to restore the b...

journal_title：Chest

authors： Gamez AS,Gras D,Petit A,Knabe L,Molinari N,Vachier I,Chanez P,Bourdin A

更新日期：2015-06-01 00:00:00

abstract：:Pulmonary encroachment by a large chronic pericardial effusion is reported in a woman with pericardiocentesis whom we recently treated. A restrictive pulmonary impairment is documented with pulmonary function data obtained before and after drainage of the effusion and the patient's dyspnea improved. ...

journal_title：Chest

authors： Kane GC,Figueroa WG

更新日期：1988-02-01 00:00:00