Abstract:
:A 72-year-old physician with myeloid metaplasia developed marked thrombocytosis, pulmonary hypertension, and right heart failure following splenectomy. No cause for the pulmonary hypertension could be found. The pulmonary hypertension and right heart failure returned to normal when hydroxyurea therapy corrected the thrombocythemia. It is concluded that thrombocytosis may cause pulmonary hypertension, mediated by pulmonary capillary obstruction from cellular components, involving platelet aggregation, microthrombosis, and stasis, and possible vasoconstrictor effects.
journal_name
Chestjournal_title
Chestauthors
Marvin KS,Spellberg RDdoi
10.1378/chest.103.2.642subject
Has Abstractpub_date
1993-02-01 00:00:00pages
642-4issue
2eissn
0012-3692issn
1931-3543pii
S0012-3692(15)41508-9journal_volume
103pub_type
杂志文章相关文献
CHEST文献大全abstract:OBJECTIVES:To investigate the time course and the relation to prognosis of coagulation and fibrinolytic abnormalities in patients with septic shock. PATIENTS AND METHODS:Forty-eight consecutive patients admitted to the medical ICU with the diagnosis of septic shock (diagnosed by defined criteria) were studied. Mortali...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.103.5.1536
更新日期:1993-05-01 00:00:00
abstract::Thoracic splenosis (post-traumatic autotransplantation of splenic tissue) is rare and generally asymptomatic. We report a patient with thoracic splenosis presenting with repeated hemoptysis. The blood supply of the hypervascular splenic transplants originated from a bronchial and an intercostal artery. Hemoptysis impr...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.102.2.626
更新日期:1992-08-01 00:00:00
abstract::The history holds the central role in distinguishing among asthma, chronic bronchitis, and emphysema. A personal or family history of atopy, a history of seasonal worsening of disease in response to a known environmental agent, perhaps seasonal, and marked variability in the severity of airflow obstruction, often with...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.87.1.35s
更新日期:1985-01-01 00:00:00
abstract::Left hemorrhagic pleural effusion was the presenting sign of painless aortic dissecting aneurysm in two elderly hypertensive patients. Computed tomography (CT) of the chest revealed the aneurysmal dilatation of the thoracic aorta and an intimal flap connecting its descending part with the left pleural space. The patie...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.106.2.636
更新日期:1994-08-01 00:00:00
abstract::This study demonstrates that when the heart is markedly displaced posteriorly to the left, or perhaps to the right, the posterior approach may make echocardiographic evaluation possible. Thus, in a patient with congenital unilateral absence of the left pulmonary artery, with marked displacement of the heart posteriorl...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.77.1.106
更新日期:1980-01-01 00:00:00
abstract:BACKGROUND:In daily clinical work, we often face delayed or recurrent pneumothorax after radiofrequency (RF) ablation for lung tumors, but a large study on this theme has not been done. Thus, we examined the rate of delayed or recurrent pneumothorax after RF ablation for lung tumors and the risk factors associated with...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.08-1499
更新日期:2009-04-01 00:00:00
abstract::Pulmonary sequestration is a congenital anomaly resulting in nonfunctioning lung tissue in either the "extralobar" or "intralobar" position. Both forms derive their blood supply from the systemic circulation. Large pulmonary sequestrations can present in the newborn with potentially fatal respiratory distress. Surgica...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.97.1.244
更新日期:1990-01-01 00:00:00
abstract::To evaluate bronchoalveolar lavage (BAL) findings in patients infected with human immunodeficiency virus (HIV), 39 patients seropositive for the virus but with no history of opportunistic infection were studied. Opportunistic organisms such as Pneumocystis carinii were not found in any of the 35 BAL fluids sent for sp...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.97.5.1066
更新日期:1990-05-01 00:00:00
abstract::This study addresses the hypothesis that patients with obstructive sleep apnea, who exhibit recurrent episodes of oxygen desaturation at night, have higher hematocrit levels than nonapneic control subjects. We prospectively studied 624 patients referred to the sleep disorders center at St. Michael's Hospital because o...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.106.3.787
更新日期:1994-09-01 00:00:00
abstract::Nineteen patients were treated at the Los Angeles County Harbor/UCLA Medical Center between 1971 and 1986 for tuberculosis of the spine. Fourteen were immigrants, a high-risk group. A high index of suspicion is required for Pott's disease, which occurs in fewer than 1 percent of patients with tuberculosis, often prese...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.95.1.145
更新日期:1989-01-01 00:00:00
abstract:STUDY OBJECTIVES:COPD patients run a risk of developing nocturnal oxygen desaturation. When evaluating patients with nocturnal hypoxemia, an unfamiliar hospital environment and the monitoring equipment may cause sleep disturbances. It was hypothesized that increased sleep disruption will lead to fewer instances of desa...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.119.6.1820
更新日期:2001-06-01 00:00:00
abstract::We report an individual with limb-girdle muscular dystrophy who has devised a way to assist her respiration by using her hands braced against the tray of her wheelchair. Utilizing this method, she was able to increase her tidal volume (VT) and lower her respiratory rate compared to unassisted spontaneous breathing, th...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.123.3.949
更新日期:2003-03-01 00:00:00
abstract:AIM:To evaluate the influence of respiratory muscle overload and right cardiac overload among the possible risk factors of hospital readmission in a 1-year follow-up of a cohort of patients with moderate-to-severe COPD. METHODS:A total of 112 COPD patients who were admitted consecutively to the hospital for acute exac...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.07-1796
更新日期:2008-04-01 00:00:00
abstract:BACKGROUND:Augmentation therapy with pooled human plasma-derived alpha(1)-antitrypsin (AAT) has been shown to have biochemical efficacy in restoring serum AAT levels above the protective threshold. Also, clinical efficacy has been suggested. OBJECTIVE:To evaluate the bioequivalence of a new solvent detergent-treated p...
journal_title:Chest
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1378/chest.122.1.66
更新日期:2002-07-01 00:00:00
abstract::Lung cancer is the leading cause of cancer-related mortality in the developed world. Non-small cell lung cancer (NSCLC) represents 85% of cases of lung cancer, and patients have a poor 5-year survival rate. Approximately one third of NSCLC patients present with early-stage disease that is amenable to potentially curat...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1378/chest.128.4.2933
更新日期:2005-10-01 00:00:00
abstract::Despite major advances in our understanding of the pathophysiologic processes leading to pulmonary arterial hypertension and recent developments in therapeutic approaches, the long-term prognosis for patients with pulmonary arterial hypertension remains unsatisfactory. Early detection and adequate clinical classificat...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1378/chest.128.6_suppl.622S-a
更新日期:2005-12-01 00:00:00
abstract::Angiosarcoma in the lung is an uncommon disorder and is usually attributable to metastasis from a primary site. Primary pulmonary angiosarcoma is extremely rare, and the prognosis of affected individuals is dismal, with most patients dying within months of presentation. Indeed, there have been no reported instances of...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.124.6.2397
更新日期:2003-12-01 00:00:00
abstract:BACKGROUND:FEV1 may remain stable while high-resolution CT (HRCT) appearances deteriorate in children with cystic fibrosis (CF). However, spirometry results commonly decline in older age groups. OBJECTIVES:To compare the rate of decline in HRCT abnormalities and spirometry results over time in an adult cohort with CF....
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.130.5.1424
更新日期:2006-11-01 00:00:00
abstract:STUDY OBJECTIVES:The findings from conventional imaging modalities, such as chest CT, are frequently unreliable in patients with lung cancer. This study was designed to compare the relative diagnostic accuracies and utility of the two most widely used functional imaging examinations, F-18-2-fluoro-2-deoxyglucose (FDG) ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.125.2.494
更新日期:2004-02-01 00:00:00
abstract:STUDY OBJECTIVE:Our objective was to compare respiratory muscle performance, pulmonary mechanics, and gas exchange between the BiPAP S/T-D ventilation system (Respironics Inc; Murrysville, PA) and the Servo Ventilator 900C (Siemens-Elma AB; Sweden) with similar inspiratory and expiratory airway pressure in patients who...
journal_title:Chest
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1378/chest.114.5.1390
更新日期:1998-11-01 00:00:00
abstract::Idiopathic bronchiolitis obliterans with organizing pneumonia (BOOP) is a clinicopathologic syndrome characterized by an indolent course and favorable prognosis. This report describes five patients with a fulminating and life-threatening variant of this syndrome. Four patients presented with respiratory failure requir...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.108.1.271
更新日期:1995-07-01 00:00:00
abstract::We studied the value of pleural fluid neuron-specific enolase as a possible diagnostic marker for pleurisy of small cell lung cancer by using enzyme immunoassay. Pleural fluid NSE levels in 12 patients with carcinomatous pleurisy due to small cell lung cancer were compared with those in 37 patients with carcinomatous ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.95.3.602
更新日期:1989-03-01 00:00:00
abstract::Neurosarcoidosis occurs in approximately 5% of patients with systemic sarcoidosis. A review of medical literature shows that intracranial mass-like lesions secondary to sarcoidosis are quite rare. CT and MRI scanning would suggest that this manifestation of neurosarcoidosis may be more common than previously realized....
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.111.2.518
更新日期:1997-02-01 00:00:00
abstract:OBJECTIVE:To estimate the incidence of work disability among adults with asthma and to evaluate a clinically based illness severity score as a predictor of such disability. DESIGN:Baseline and follow-up telephone interviews and medical record review. SETTING:University-based outpatient pulmonary specialty practice. ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.104.5.1371
更新日期:1993-11-01 00:00:00
abstract:STUDY OBJECTIVE:Bronchioloalveolar carcinoma (BAC) is an uncommon pulmonary neoplasm with various radiologic and clinical presentations. In this article, we analyze the initial radiologic findings, TNM stagings, surgical types, and radiologic features of recurrence, and correlate them with patient survival. DESIGN:A r...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.118.4.940
更新日期:2000-10-01 00:00:00
abstract::In two patients a documented Texas A2 influenza infection was associated with the development of interstitial pulmonary disease. One patient had an acute fulminating process resulting in respiratory failure and necessitating ventilatory assistance. Open lung biopsy revealed a histologic picture consistent with usual i...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.80.2.123
更新日期:1981-08-01 00:00:00
abstract::Bronchopulmonary endometriosis is a rare cause of hemoptysis. We describe a woman with catamenial hemoptysis which was localized with chest CAT scanning and treated successfully with danazol. The proposed pathogenesis and manifestations of thoracic endometriosis are reviewed, and the use of new diagnostic and therapeu...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.87.5.687
更新日期:1985-05-01 00:00:00
abstract:OBJECTIVE:To compare sublingual PCO(2) (PslCO(2)) measurements with gastric intramucosal PCO(2) (PimCO(2)) as well as with the traditional indexes of tissue oxygenation in hemodynamically unstable ICU patients. DESIGN:A prospective, validation study. SETTING:The medical and coronary ICUs of a community teaching hospi...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.120.3.923
更新日期:2001-09-01 00:00:00
abstract:BACKGROUND:The reported experience is sparse for patients with prior pneumonectomy who are undergoing surgery for ischemic or valvular heart disease. Such surgery poses special technical challenges. To expand the experience with this challenging clinical intervention, we reviewed the reported patients with prior pneumo...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1378/chest.06-2545
更新日期:2007-07-01 00:00:00
abstract::A post-right pneumonectomy syndrome is described which manifests symptoms of exertional dyspnea and inspiratory stridor on rapid inspiration. These symptoms were associated with marked rightward and posterior deviation of the trachea, over-distention of the left lung with its herniation into the right side of the ches...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.75.1.78
更新日期:1979-01-01 00:00:00