Bronchoalveolar lavage findings in patients seropositive for the human immunodeficiency virus (HIV).

Abstract:

:To evaluate bronchoalveolar lavage (BAL) findings in patients infected with human immunodeficiency virus (HIV), 39 patients seropositive for the virus but with no history of opportunistic infection were studied. Opportunistic organisms such as Pneumocystis carinii were not found in any of the 35 BAL fluids sent for special stains and cultures. Three of 16 (18 percent) BAL fluids sent for HIV culture were positive compared with a 60.9 percent blood HIV culture positivity in the same group. To evaluate cellular recovery, the patients were divided into Walter Reed (WR) groups 1 and 2 (blood CD4 greater than or equal to 400/cu mm) and WR3 to WR5 (blood CD4 less than 400/cu mm). Compared with ten nonsmoking healthy controls, the WR1 and WR2 group had a greater overall cellular recovery but this was not statistically significant when the smokers were excluded. There was no difference in macrophage or lymphocyte percentages in either patient group compared with controls. T-cell subset analysis of a small group of WR1 to WR5 patient BAL fluids revealed no difference in CD4 numbers or the CD4/CD8 rate between WR1 and WR2 and WR3 to WR5 patients. We conclude that opportunistic pulmonary infection is unlikely in HIV-seropositive patients with normal chest roentgenograms despite symptoms of dyspnea on exertion. Also, HIV can be isolated from BAL fluid from these patients although not as often as from blood. Finally, there appears to be no distinct progression in BAL cellular findings before the onset of acquired immunodeficiency syndrome.

journal_name

Chest

journal_title

Chest

authors

Johnson JE,Anders GT,Hawkes CE,LaHatte LJ,Blanton HM

doi

10.1378/chest.97.5.1066

subject

Has Abstract

pub_date

1990-05-01 00:00:00

pages

1066-71

issue

5

eissn

0012-3692

issn

1931-3543

pii

S0012-3692(15)40999-7

journal_volume

97

pub_type

杂志文章

相关文献

CHEST文献大全
  • Essential thrombocythemia and coronary artery disease.

    abstract::An unusual case of essential thrombocythemia in a young man presenting with progressive angina pectoris is presented. Angiography revealed proximal left anterior descending artery stenosis. Successful percutaneous transluminal angioplasty along with antiplatelet therapy and a calcium channel blocking drug have rendere...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.86.6.933

    authors: Hanger KH Jr,Kilgore J,James E

    更新日期:1984-12-01 00:00:00

  • The role of thoracic radiotherapy in the management of limited-stage small cell lung cancer: past, present, and future.

    abstract::The role of thoracic radiation therapy in the management of limited-stage small cell lung cancer (SCLC) is reviewed. Although chest irradiation has been used to treat SCLC for over four decades, its standard role in the management of limited-stage disease was established only during the last decade. Multiple prospecti...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.112.4_supplement.259s

    authors: Kumar P

    更新日期:1997-10-01 00:00:00

  • Tracheal bronchus: a cause of prolonged atelectasis in intubated children.

    abstract::Tracheal bronchus is a common anomaly that occurs in approximately 2% of people. Two children with multiple medical problems which led to endotracheal intubation are described. The hospital course for each child was complicated by persistent right upper lobe atelectasis. The presence of a tracheal bronchus was not rec...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.113.2.537

    authors: O'Sullivan BP,Frassica JJ,Rayder SM

    更新日期:1998-02-01 00:00:00

  • Localized Wegener's granulomatosis relapsing as diffuse massive intra-alveolar hemorrhage.

    abstract::In a 75-year-old patient presenting with a solitary pulmonary mass, a localized form of Wegener's granulomatosis was diagnosed after lobectomy. In the absence of extrapulmonary manifestations and after a benign postoperative course, the patients was discharged without medical treatment. Three months later, diffuse alv...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.104.3.955

    authors: Odeh M,Best LA,Kerner H,Bassan H,Oliven A

    更新日期:1993-09-01 00:00:00

  • The echocardiographic diagnosis of rupture of a papillary muscle.

    abstract::The echocardiographic diagnosis of acute rupture of a papillary muscle is described. The pertinent findings included (1) decreased systolic motion of the posterior wall, (2) exaggerated septal motion, (3) left ventricular enlargement and pattern suggesting left ventricular diastolic overload, and (4) bizarre flutterin...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.73.2.232

    authors: Ahmad S,Kleiger RE,Connors J,Krone R

    更新日期:1978-02-01 00:00:00

  • Peripheral arterial embolism due to a left ventricular diverticulum in a young adult.

    abstract::A 32-year-old man was admitted to the emergency department of our hospital after experiencing a peripheral arterial embolism. Investigation of the possible embolic sources in an otherwise asymptomatic patient revealed the existence of a left ventricular diverticulum. The left ventricular diverticulum is a rare congeni...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.127.4.1452

    authors: Parthenakis FI,Kochiadakis GE,Patrianakos AP,Hamilos MI,Mitrouska I,Katsamouris AN,Vardas PE

    更新日期:2005-04-01 00:00:00

  • Regulation of breathing and perception of dyspnea in healthy pregnant women.

    abstract:STUDY OBJECTIVE:To examine if the perception of dyspnea during normal pregnancy may be related to an inappropriate ventilatory response to the increased metabolic rate, due to a higher chemosensitivity. PATIENTS AND INTERVENTIONS:At weeks 12, 24, and 36 of gestation and 4 months after delivery, 11 healthy pregnant wom...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.110.2.446

    authors: García-Rio F,Pino JM,Gómez L,Alvarez-Sala R,Villasante C,Villamor J

    更新日期:1996-08-01 00:00:00

  • Tension fecal pneumothorax in a postpartum patient.

    abstract::A 20-year-old woman developed severe shortness of breath 4 h after a cesarean section. Chest roentgenogram showed a pleural effusion and tension pneumothorax; insertion of a chest tube drained liquid stool. At surgery she was found to have a left diaphragmatic defect with herniation, strangulation, and perforation of ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.103.3.950

    authors: Lacayo L,Taveras JM 3rd,Sosa N,Ratzan KR

    更新日期:1993-03-01 00:00:00

  • Lung ultrasound in the diagnosis and follow-up of community-acquired pneumonia: a prospective, multicenter, diagnostic accuracy study.

    abstract:BACKGROUND:The aim of this prospective, multicenter study was to define the accuracy of lung ultrasound (LUS) in the diagnosis of community-acquired pneumonia (CAP). METHODS:Three hundred sixty-two patients with suspected CAP were enrolled in 14 European centers. At baseline, history, clinical examination, laboratory ...

    journal_title:Chest

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1378/chest.12-0364

    authors: Reissig A,Copetti R,Mathis G,Mempel C,Schuler A,Zechner P,Aliberti S,Neumann R,Kroegel C,Hoyer H

    更新日期:2012-10-01 00:00:00

  • Work disability among adults with asthma.

    abstract:OBJECTIVE:To estimate the incidence of work disability among adults with asthma and to evaluate a clinically based illness severity score as a predictor of such disability. DESIGN:Baseline and follow-up telephone interviews and medical record review. SETTING:University-based outpatient pulmonary specialty practice. ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.104.5.1371

    authors: Blanc PD,Jones M,Besson C,Katz P,Yelin E

    更新日期:1993-11-01 00:00:00

  • Concomitant assessment of depth of sedation by changes in bispectral index and changes in autonomic variables (heart rate and/or BP) in pediatric critically ill patients receiving neuromuscular blockade.

    abstract:OBJECTIVE:We evaluated whether or not changes in bispectral index (BIS) are associated with concomitant changes in autonomic variables that are in agreement with the different level of sedation that the changes in BIS indicate. DESIGN:A retrospective chart review. SETTING:A pediatric ICU of a children's hospital. ME...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.128.1.303

    authors: Trope RM,Silver PC,Sagy M

    更新日期:2005-07-01 00:00:00

  • Depression is more common in girls with nonatopic asthma.

    abstract:BACKGROUND:Asthma may increase the risk of comorbid depressive disorders in children. Children suffering from asthma or depression are more often overweight. We examined whether depression was more likely in children with atopic and nonatopic asthma, independent of abdominal adiposity. METHODS:A cross-sectional analys...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.11-0219

    authors: Bahreinian S,Ball GDC,Colman I,Becker AB,Kozyrskyj AL

    更新日期:2011-11-01 00:00:00

  • AIDS and malignant mesothelioma--is there a connection?

    abstract::A 35-year-old male homosexual, a former intravenous drug abuser, was found to be human immunodeficiency virus (HIV) positive in 1984. He developed AIDS in 1987 and began treatment with zidovudine in 1989. One year later he developed left apical pleural blebs, a pneumothorax and an exudative pleural effusion. A maligna...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.103.4.1268

    authors: Behling CA,Wolf PL,Haghighi P

    更新日期:1993-04-01 00:00:00

  • High rhinovirus burden in lower airways of children with cystic fibrosis.

    abstract:BACKGROUND:Rhinovirus (RV)-induced pulmonary exacerbations are common in cystic fibrosis (CF) and have been associated with impaired virus clearance by the CF airway epithelium in vitro. Here, we assess in vivo the association of RV prevalence and load with antiviral defense mechanisms, airway inflammation, and lung fu...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.12-0954

    authors: Kieninger E,Singer F,Tapparel C,Alves MP,Latzin P,Tan HL,Bossley C,Casaulta C,Bush A,Davies JC,Kaiser L,Regamey N

    更新日期:2013-03-01 00:00:00

  • Reduced sodium transport with nasal administration of the prostasin inhibitor camostat in subjects with cystic fibrosis.

    abstract:BACKGROUND:Prostasin, a trypsin-like serine protease, is a channel-activating protease and major regulator of epithelial sodium channel-mediated sodium absorption. Its direct inhibition by camostat represents a potential approach to inhibiting sodium transport in cystic fibrosis (CF). METHODS:To determine whether a to...

    journal_title:Chest

    pub_type: 杂志文章,随机对照试验

    doi:10.1378/chest.12-2431

    authors: Rowe SM,Reeves G,Hathorne H,Solomon GM,Abbi S,Renard D,Lock R,Zhou P,Danahay H,Clancy JP,Waltz DA

    更新日期:2013-07-01 00:00:00

  • Relationship between ICU design and mortality.

    abstract:BACKGROUND:Architectural design of health-care facilities can influence patient safety; however, it is unknown whether patient outcomes are significantly affected by ICU design. METHODS:Six hundred sixty-four patients admitted to the medical ICU (MICU) of Columbia University Medical Center during 2008 were included in...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.09-1458

    authors: Leaf DE,Homel P,Factor PH

    更新日期:2010-05-01 00:00:00

  • Iatrogenic delirium and coma: a "near miss".

    abstract::A 66-year-old woman was cared for at two referral institutions following a witnessed cardiac arrest in a local emergency department. Despite aggressive initial care, she failed to regain consciousness during a 28-day course. Based on an erroneous neurologic diagnosis of anoxic encephalopathy, pessimism regarding likel...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.08-0471

    authors: Dunn WF,Adams SC,Adams RW

    更新日期:2008-05-01 00:00:00

  • Bronchiolitis obliterans and Nocardia asteroides infection of the lung.

    abstract::This report describes a patient with right lower lung (RLL) pneumonia of a subacute nature. Sputum and bronchial washings both grew N asteroides. Open lung biopsy showed bronchiolitis obliterans. Both the clinical and radiologic picture dramatically improved during three weeks of treatment with trimethoprim and sulfam...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.92.6.1107

    authors: Camp M,Mehta JB,Whitson M

    更新日期:1987-12-01 00:00:00

  • A comparative study of two angiogenic factors: vascular endothelial growth factor and angiogenin in induced sputum from asthmatic children in acute attack.

    abstract:BACKGROUND:Angiogenesis is a prerequisite for airway remodeling in bronchial asthma. Several factors may play important roles in inflammation and angiogenesis through effects on inflammatory cell infiltration or neovascularization. OBJECTIVES:(1) To determine the levels of vascular endothelial growth factor (VEGF) and...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.129.2.266

    authors: Abdel-Rahman AM,el-Sahrigy SA,Bakr SI

    更新日期:2006-02-01 00:00:00

  • Orthostatic and exercise-induced advanced nodal atrioventricular block.

    abstract::A 69-year-old woman was referred for asthenia and dizziness when walking in the last two months. No clinical abnormalities were found, and sinus rhythm was present when lying down. On orthostatism and walking, advanced AV block developed. Atropine and isoproterenol ameliorated the AV conduction abnormality, suggesting...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.102.3.970

    authors: Reig J,Domingo E,Reguant J,Corrons J

    更新日期:1992-09-01 00:00:00

  • Sulfasalazine-induced pulmonary disease.

    abstract::We report the findings in two patients with sulfasalazine-induced pulmonary disease. The first patient developed pulmonary interstitial fibrosis after more than 4 yr of treatment for Crohn's disease. Pulmonary symptoms and chest roentgenographic and pulmonary function abnormalities gradually reversed after stopping th...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.101.4.1033

    authors: Hamadeh MA,Atkinson J,Smith LJ

    更新日期:1992-04-01 00:00:00

  • Loculated interlobar air-fluid collection in congestive heart failure.

    abstract::Two patients are described who had congestive heart failure with loculated interlobar air-fluid collections. Although pseudotumor (interlobar effusion) is a well-known finding in congestive heart failure, the additional presence of air is unique. Both are somewhat related to the underlying failure. ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.74.6.681

    authors: Rabinowitz JG,Kongtawng T

    更新日期:1978-12-01 00:00:00

  • Sex differences in awake ventilatory drive and abnormal breathing during sleep in eucapnic obesity.

    abstract::We studied hypoxic and hypercapnic ventilatory drives in 22 eucapnic obese subjects (14 female and eight male subjects) referred for weight reduction therapy and 23 normal subjects (eight female and 15 male subjects). In the female subjects, both occlusion pressure, currently used as an indicator of ventilatory drive,...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.93.5.968

    authors: Kunitomo F,Kimura H,Tatsumi K,Kuriyama T,Watanabe S,Honda Y

    更新日期:1988-05-01 00:00:00

  • Desquamative interstitial pneumonitis in children.

    abstract::Interstitial pneumonitis in children is a rare and poorly understood disease. Controversy exists as to whether the varoius histologic changes encountered represent different disease or a spectrum of the same disease. Fourteen biopsy-confirmed cases of desquamative interstitial pneumonitis in children were seen at the ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.77.2.165

    authors: Stillwell PC,Norris DG,O'Connell EJ,Rosenow EC 3rd,Weiland LH,Harrison EG Jr

    更新日期:1980-02-01 00:00:00

  • Plasma Mitochondrial DNA Levels Are Associated With ARDS in Trauma and Sepsis Patients.

    abstract:BACKGROUND:Critically ill patients who develop ARDS have substantial associated morbidity and mortality. Circulating mitochondrial DNA (mtDNA) released during critical illness causes endothelial dysfunction and lung injury in experimental models. This study hypothesized that elevated plasma mtDNA is associated with ARD...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1016/j.chest.2019.09.028

    authors: Faust HE,Reilly JP,Anderson BJ,Ittner CAG,Forker CM,Zhang P,Weaver BA,Holena DN,Lanken PN,Christie JD,Meyer NJ,Mangalmurti NS,Shashaty MGS

    更新日期:2020-01-01 00:00:00

  • Abnormal swallowing reflex and COPD exacerbations.

    abstract:BACKGROUND:It is unclear whether an abnormal swallowing reflex affects COPD exacerbations. This study investigated the prevalence of abnormal swallowing reflexes and its relationship with COPD exacerbation prospectively. We also clarified its association with gastroesophageal reflux disease (GERD) and airway bacterial ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.09-0482

    authors: Terada K,Muro S,Ohara T,Kudo M,Ogawa E,Hoshino Y,Hirai T,Niimi A,Chin K,Mishima M

    更新日期:2010-02-01 00:00:00

  • Survival in systemic sclerosis with pulmonary arterial hypertension has not improved in the modern era.

    abstract:BACKGROUND:The impact of modern therapy on survival in pulmonary arterial hypertension (PAH) associated with systemic sclerosis (SSc) is not clear. We sought to determine associations among commonly used clinical and hemodynamic variables, treatment, and long-term survival in PAH associated with SSc compared with PAH d...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.12-0653

    authors: Rubenfire M,Huffman MD,Krishnan S,Seibold JR,Schiopu E,McLaughlin VV

    更新日期:2013-10-01 00:00:00

  • Influence of autonomic neuropathy of different severities on the hypercapnic drive to breathing in diabetic patients.

    abstract::To investigate the effects of the autonomic nervous system on control of breathing, the neuromuscular (mouth occlusion pressure at 0.1 s after onset of inspiration [P0.1]) and ventilatory (minute ventilation [VE]) response to progressive hyperoxic hypercapnia was assessed in diabetic patients with autonomic dysfunctio...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.112.1.145

    authors: Tantucci C,Scionti L,Bottini P,Dottorini ML,Puxeddu E,Casucci G,Sorbini CA

    更新日期:1997-07-01 00:00:00

  • Diagnostic value of medical thoracoscopy in pleural disease: a 6-year retrospective study.

    abstract:STUDY OBJECTIVES:Unlike thoracocentesis and closed pleural biopsy (CPB), medical thoracoscopy permits biopsy with direct visualization. In a 6-year retrospective study of patients having undergone at least one medical thoracoscopy, we analyzed the diagnostic yield of thoracoscopy and its value in the management of pleu...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.121.5.1677

    authors: Blanc FX,Atassi K,Bignon J,Housset B

    更新日期:2002-05-01 00:00:00

  • Proteomics in pulmonary medicine.

    abstract::Proteomics is the study of the entire protein complement of the genome (the proteome) in a biological system. Proteomic studies require a multidisciplinary approach and have only been practical with the convergence of technical and methodologic improvements including the following: advances in mass spectrometry and ge...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.130.2.567

    authors: Bowler RP,Ellison MC,Reisdorph N

    更新日期:2006-08-01 00:00:00