Sulfasalazine-induced pulmonary disease.

Abstract:

:We report the findings in two patients with sulfasalazine-induced pulmonary disease. The first patient developed pulmonary interstitial fibrosis after more than 4 yr of treatment for Crohn's disease. Pulmonary symptoms and chest roentgenographic and pulmonary function abnormalities gradually reversed after stopping the drug. No specific treatment was given. The second patient, who had rheumatoid arthritis without pulmonary disease, received the drug for 1 yr without experiencing any problems. Readministration seven months later resulted in the development of an acute interstitial pulmonary disease. Discontinuing the drug and treatment with corticosteroids produced rapid improvement. We discuss these patients in relation to other reports of sulfasalazine-induced pulmonary toxicity, highlighting their atypical features.

journal_name

Chest

journal_title

Chest

authors

Hamadeh MA,Atkinson J,Smith LJ

doi

10.1378/chest.101.4.1033

subject

Has Abstract

pub_date

1992-04-01 00:00:00

pages

1033-7

issue

4

eissn

0012-3692

issn

1931-3543

pii

S0012-3692(16)32724-6

journal_volume

101

pub_type

杂志文章

相关文献

CHEST文献大全
  • How Common Is Airflow Limitation in Patients With Emphysema on CT Scan of the Chest?

    abstract:BACKGROUND:COPD has traditionally been defined by the presence of irreversible airflow limitation on spirometry using either the GOLD (Global Initiative for Chronic Obstructive Lung Disease) or American Thoracic Society/European Respiratory Society criteria (lower limit of normal [LLN]). We have observed that some pati...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.14-1556

    authors: Lutchmedial SM,Creed WG,Moore AJ,Walsh RR,Gentchos GE,Kaminsky DA

    更新日期:2015-07-01 00:00:00

  • Quadriceps fatigue after cycle exercise in patients with COPD compared with healthy control subjects.

    abstract:STUDY OBJECTIVES:Quadriceps fatigue can occur in patients with COPD after exhaustive cycle exercise. The purpose of this study was to determine whether the degree of fatigue elicited by cycle exercise was greater in patients with COPD compared with matched control subjects. SUBJECTS:Nine male patients with COPD with a...

    journal_title:Chest

    pub_type: 临床试验,杂志文章

    doi:10.1378/chest.123.4.1104

    authors: Mador MJ,Bozkanat E,Kufel TJ

    更新日期:2003-04-01 00:00:00

  • Treatment of bronchial asthma with terbutaline inhaled by conespacer combined with positive expiratory pressure mask.

    abstract::The influence of positive expiratory pressure (PEP) applied during inhalation of a beta 2-agonist in treatment of bronchial asthma was investigated in a randomized crossover study with two-week treatment periods. In one period, two puffs (0.5 mg) of terbutaline was given from a metered dose inhaler and inhaled through...

    journal_title:Chest

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1378/chest.100.2.317

    authors: Frischknecht-Christensen E,Nørregaard O,Dahl R

    更新日期:1991-08-01 00:00:00

  • Detection of intrapulmonary shunts in schistosomal cor pulmonale.

    abstract::Two patients with schistosomal cor pulmonale and central cyanosis were studied by contrast-enhanced echocardiography, using indocyanine green injection. Intrapulmonary shunts were detected by this method. To our knowledge, this is the first report that proves the presence of intrapulmonary shunts in schistosomal cor p...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.104.4.1280

    authors: Rafla SM,Sourour S

    更新日期:1993-10-01 00:00:00

  • Fluid balance during pulmonary edema. Is fluid gain a marker or a cause of poor outcome?

    abstract:STUDY OBJECTIVE:To evaluate the importance of fluid balance and changes in extravascular lung water (EVLW) on survival in the ICU and short-term outcome in patients with pulmonary edema. DESIGN:Retrospective analysis of data (sorting by survival and "treatment received") from a recent randomized controlled trial of fl...

    journal_title:Chest

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1378/chest.100.4.1068

    authors: Schuller D,Mitchell JP,Calandrino FS,Schuster DP

    更新日期:1991-10-01 00:00:00

  • Treatment of chronic obstructive pulmonary disease with corticosteroids. Comparison of daily vs alternate-day therapy.

    abstract::We compared the efficacy of corticosteroid therapy initiated as an alternate-day regimen to that of a four-times-daily regimen in patients with stable chronic obstructive pulmonary disease. In this double-blind study, 44 patients with moderate to severe COPD (mean FEV1 740 +/- 310 ml) were hospitalized and randomly al...

    journal_title:Chest

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1378/chest.86.4.524

    authors: Blair GP,Light RW

    更新日期:1984-10-01 00:00:00

  • Diffuse alveolar hemorrhage following alemtuzumab.

    abstract::This study describes an unusual patient with X-linked Alport syndrome (XLAS) in whom diffuse alveolar hemorrhage (DAH) developed as a complication of alemtuzumab therapy following renal transplantation. A 26-year-old man with XLAS underwent retransplantation with a cadaveric renal allograft. He received alemtuzumab th...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.07-2354

    authors: Sachdeva A,Matuschak GM

    更新日期:2008-06-01 00:00:00

  • Prolonged endotracheal intubation.

    abstract::The advisability of prolonged oral or nasotracheal intubation is of continuing concern to physicians caring for patients requiring prolonged mechanical ventilatory assistance. Currently, in many health care centers, prolonged intubation is defined as being in excess of seven days. We treated a patient who required mec...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.76.1.110

    authors: Vogelhut MM,Downs JB

    更新日期:1979-07-01 00:00:00

  • Respiratory changes in aortic blood velocity as an indicator of fluid responsiveness in ventilated patients with septic shock.

    abstract:STUDY OBJECTIVE:To investigate whether the respiratory changes in peak velocity (Vpeak) of aortic blood flow could be related to the effects of volume expansion on cardiac index. DESIGN:Prospective clinical study. SETTING:Medical ICUs of a university hospital (20 beds) and of a nonuniversity hospital (15 beds). PATI...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.119.3.867

    authors: Feissel M,Michard F,Mangin I,Ruyer O,Faller JP,Teboul JL

    更新日期:2001-03-01 00:00:00

  • Effects of flecainide and propafenone on systolic performance in subjects with normal cardiac function.

    abstract::Flecainide and propafenone are effective in suppressing both ventricular and supraventricular tachyarrhythmias, but their efficacy is often limited by dose-related side effects. This study was performed to evaluate noninvasively the effects of intravenous flecainide and propafenone on left ventricular systolic functio...

    journal_title:Chest

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1378/chest.103.4.1068

    authors: Santinelli V,Arnese M,Oppo I,Matarazzi C,Maione S,Palma M,Giunta A

    更新日期:1993-04-01 00:00:00

  • Comparative Effectiveness of Proton Pump Inhibitors vs Histamine Type 2 Receptor Blockers for Preventing Clinically Important Gastrointestinal Bleeding During Intensive Care: A Population-Based Study.

    abstract:BACKGROUND:Proton pump inhibitors (PPIs) and histamine type 2 receptor blockers (H2Bs) are used for stress ulcer prophylaxis. Although the PPIs have greater potency for acid suppression, their relative effectiveness for preventing clinically important GI bleeding (CIGIB) has not been established. The goal of this study...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1016/j.chest.2018.05.015

    authors: Lilly CM,Aljawadi M,Badawi O,Onukwugha E,Tom SE,Magder LS,Harris I

    更新日期:2018-09-01 00:00:00

  • Calcified plaque in the superior portion of the major fissure. An unusual manifestation of asbestos exposure.

    abstract::Parietal pleural plaque is a well-recognized sign of exposure to asbestos. Visceral pleural involvement is an uncommon manifestation, and calcified visceral pleural plaques are rare. Those reported have been in the minor fissure and inferior major fissure. We describe a unique calcified plaque in the superior major fi...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.96.6.1436

    authors: Rupp SB,Jolles H

    更新日期:1989-12-01 00:00:00

  • Systemic bioavailability and potency of high-dose inhaled corticosteroids: a comparison of four inhaler devices and three drugs in healthy adult volunteers.

    abstract:OBJECTIVES:To compare the systemic bioavailability (assessed by cortisol suppression) of high-dose budesonide when given by four inhaler devices and orally. Also studied are the relative systemic potencies of three inhaled steroids (budesonide, fluticasone propionate, and beclomethasone dipropionate) when given by mete...

    journal_title:Chest

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1378/chest.115.5.1278

    authors: Wales D,Makker H,Kane J,McDowell P,O'Driscoll BR

    更新日期:1999-05-01 00:00:00

  • COPD can mimic the appearance of pneumothorax on thoracic ultrasound.

    abstract:PURPOSES:To determine the diagnostic accuracy of ultrasound in the diagnosis of pneumothorax in patients with COPD with particular regard to false-positive diagnoses. MATERIALS AND METHODS:This was a single-center, prospective, blinded study. Nine patients with pneumothorax, 9 patients with cystic fibrosis, 17 patient...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.129.3.545

    authors: Slater A,Goodwin M,Anderson KE,Gleeson FV

    更新日期:2006-03-01 00:00:00

  • Impact of habitual cocaine smoking on the physiologic response to maximum exercise.

    abstract:BACKGROUND:Habitual smoking of alkaloidal cocaine (crack) has been reported to be associated with a number of cardiopulmonary complications that may not be clinically obvious but could potentially interfere with normal physiologic responses to exercise and thus impair maximum exercise performance. STUDY OBJECTIVE:To e...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.112.4.1008

    authors: Marques-Magallanes JA,Koyal SN,Cooper CB,Kleerup EC,Tashkin DP

    更新日期:1997-10-01 00:00:00

  • Inhaled furosemide is not effective in acute asthma.

    abstract::As previous studies have suggested that inhaled furosemide may have a protective effect against certain types of provocative challenges in asthmatic subjects, we investigated the role of furosemide in treating acute asthma exacerbations. Twenty-four patients (n = 24) with acute asthma were entered into the study on pr...

    journal_title:Chest

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1378/chest.106.5.1396

    authors: Karpel JP,Dworkin F,Hager D,Feliciano S,Shapiro D,Posner L,Luks D

    更新日期:1994-11-01 00:00:00

  • Sarcoidosis Diagnostic Score: A Systematic Evaluation to Enhance the Diagnosis of Sarcoidosis.

    abstract:BACKGROUND:The diagnosis of sarcoidosis is made by the combination of clinical features and biopsy results. The clinical features of sarcoidosis can be quite variable. We developed a Sarcoidosis Diagnostic Score (SDS) to summarize the clinical features of patients with possible sarcoidosis. METHODS:Biopsy-confirmed pa...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1016/j.chest.2018.05.003

    authors: Bickett AN,Lower EE,Baughman RP

    更新日期:2018-11-01 00:00:00

  • Outcome after right middle lobe syndrome.

    abstract::The long-term pulmonary consequences of right middle lobe syndrome (RMLS) in childhood are not known. Therefore, outcome was evaluated in 17 children with RMLS diagnosed in early childhood (mean age, 3.3 years; SD, 1.1 year). Mean age at follow-up was 10.1 years (SD, 2.6 years). RMLS was defined as atelectasis of the ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.108.1.150

    authors: De Boeck K,Willems T,Van Gysel D,Corbeel L,Eeckels R

    更新日期:1995-07-01 00:00:00

  • Direct mechanical ventricular actuation for cardiac arrest in humans. A clinical feasibility trial.

    abstract::Direct mechanical ventricular actuation (DMVA) is a non-blood-contacting method of biventricular cardiac massage which may be applied expediently for total circulatory support. The purpose of this study was to assess the feasibility of DMVA application for patients suffering refractory cardiac arrest. Following inform...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.100.1.86

    authors: Anstadt MP,Bartlett RL,Malone JP,Brown GR,Martin S,Nolan DJ,Oberheu KH,Anstadt GL

    更新日期:1991-07-01 00:00:00

  • Variation in Patient Smoking Cessation Rates Among Health-Care Providers: An Observational Study.

    abstract:BACKGROUND:Physicians play a crucial role in providing smoking cessation counseling and medications. However, it is unknown whether individual physicians' approaches affect whether patients quit. RESEARCH QUESTION:This study assessed patient quit rates within a national quality-improvement learning collaborative to do...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1016/j.chest.2020.05.599

    authors: Almaaitah S,Ciemins EL,Joshi V,Arora A,Meskow C,Rothberg MB

    更新日期:2020-11-01 00:00:00

  • Persistent Challenges in Pediatric Pulmonary Hypertension.

    abstract::Pulmonary hypertension and related pulmonary vascular diseases cause significant morbidities and high mortality and present many unique challenges toward improving outcomes in neonates, infants, and children. Differences between pediatric and adult disease are reflected in controversies regarding etiologies, classific...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1016/j.chest.2016.01.007

    authors: Hopper RK,Abman SH,Ivy DD

    更新日期:2016-07-01 00:00:00

  • Noninvasive positive-pressure ventilation facilitates tracheal extubation after laryngotracheal reconstruction in children.

    abstract::Tracheal extubation after laryngotracheal reconstruction in children may be complicated by postoperative tracheal edema and pulmonary dysfunction. The replacement of a tracheal tube in this situation may exacerbate the existing injury to the tracheal mucosa, complicating subsequent attempts at tracheal extubation. We ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.116.1.260

    authors: Hertzog JH,Siegel LB,Hauser GJ,Dalton HJ

    更新日期:1999-07-01 00:00:00

  • Effects of inhaled anticholinergic drug on dyspnea and gas exchange during exercise in patients with chronic obstructive pulmonary disease.

    abstract::To elucidate the effect of oxitropium bromide (OTB), an anticholinergic drug, on dyspnea and gas exchange during exercise in patients with chronic obstructive pulmonary disease (COPD), we performed the cycle exercise test on 19 patients with COPD (mean age, 72.0 +/- 1.9 years; mean FEV1, 1.28 +/- 0.07 L) before and af...

    journal_title:Chest

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1378/chest.103.6.1774

    authors: Teramoto S,Fukuchi Y,Orimo H

    更新日期:1993-06-01 00:00:00

  • Recent Dieulafoy's lesion bleeding and massive pulmonary emboli. Successful use of thrombolytic therapy.

    abstract::A massive GI bleed secondary to a Dieulafoy's lesion developed in a 77-year-old woman. Fifteen days later, massive pulmonary emboli developed. We describe successful thrombolytic treatment of her pulmonary emboli without complicating GI hemorrhage. ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.110.2.567

    authors: Levin MS,Vernovsky I,Beer DJ

    更新日期:1996-08-01 00:00:00

  • Diaphragm Weakness in the Critically Ill: Basic Mechanisms Reveal Therapeutic Opportunities.

    abstract::The diaphragm is the primary muscle of inspiration. Its capacity to respond to the load imposed by pulmonary disease is a major determining factor both in the onset of ventilatory failure and in the ability to successfully separate patients from ventilator support. It has recently been established that a very large pr...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1016/j.chest.2018.08.1028

    authors: Petrof BJ

    更新日期:2018-12-01 00:00:00

  • Bone marrow-derived cells contribute to pulmonary vascular remodeling in hypoxia-induced pulmonary hypertension.

    abstract:STUDY OBJECTIVE:In these days, it was reported that bone marrow (BM) cells might take part in the remodeling of some systemic vascular diseases; however, it remains unknown whether the BM cells were involved in the vascular remodeling of pulmonary arteries and the progression of pulmonary hypertension (PH). The purpose...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.127.5.1793

    authors: Hayashida K,Fujita J,Miyake Y,Kawada H,Ando K,Ogawa S,Fukuda K

    更新日期:2005-05-01 00:00:00

  • Bilateral phrenic paralysis in a patient with systemic lupus erythematosus.

    abstract::Respiratory manifestations of systemic lupus erythematosus (SLE) are frequent. They include respiratory muscle abnormalities, which have been implicated in the pathogenesis of the "shrinking lung syndrome" (SLS). We report the case of a patient with this syndrome, in whom diaphragmatic paralysis due to demyelinating p...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.119.4.1274

    authors: Hardy K,Herry I,Attali V,Cadranel J,Similowski T

    更新日期:2001-04-01 00:00:00

  • Measurement of respiratory acoustic signals. Effect of microphone air cavity width, shape, and venting.

    abstract:STUDY OBJECTIVE:We have previously investigated the effects of microphone type and coupler air chamber depth on lung sound characteristics. We now report the results of experiments exploring the effects of air chamber width, shape, and venting on lung sounds. DESIGN:We used a single electret microphone with a variety ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.108.4.1004

    authors: Kraman SS,Wodicka GR,Oh Y,Pasterkamp H

    更新日期:1995-10-01 00:00:00

  • Interpreting periodic lung function tests in individuals: the relationship between 1- to 5-year and long-term FEV1 changes.

    abstract:STUDY OBJECTIVE:Spirometry is performed to monitor lung health, but variability between tests can hinder recognition of excessive FEV(1) declines. We sought to describe the relationship between FEV(1) changes over 1 to 5 years and FEV(1) declines over longer terms, using 21,821 test results from 1,884 workers who parti...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.130.2.493

    authors: Wang ML,Avashia BH,Petsonk EL

    更新日期:2006-08-01 00:00:00

  • Epidemiology and outcomes of clostridium difficile-associated disease among patients on prolonged acute mechanical ventilation.

    abstract:PURPOSES:Patients receiving prolonged acute mechanical ventilation (PAMV), although comprising a third of all mechanical ventilation (MV) patients, consume two-thirds of all the resources allocated to MV, and their numbers are projected to double by 2020. By virtue of their prolonged hospital length of stay (median LOS...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.09-0596

    authors: Zilberberg MD,Nathanson BH,Sadigov S,Higgins TL,Kollef MH,Shorr AF

    更新日期:2009-09-01 00:00:00