Quadriceps fatigue after cycle exercise in patients with COPD compared with healthy control subjects.

abstract：:In a prospective study, 11 (1.5 percent) of 742 patients had angiographically proven coronary artery aneurysms. The clinical picture was similar to that of patients with severe coronary artery disease. The coronary artery aneurysms were multiple and were associated with extensive coronary atherosclerosis in ten of the...

journal_title：Chest

authors： Falsetti HL,Carrol RJ

更新日期：1976-05-01 00:00:00

abstract：STUDY OBJECTIVE:To determine the effect of a symptom-based and a peak flow-based action plan in preventing acute exacerbations in subjects with poorly controlled asthma. DESIGN:A randomized controlled trial in which subjects who had required urgent treatment for their asthma were allocated to receive no action plan, a...

journal_title：Chest

authors： Cowie RL,Revitt SG,Underwood MF,Field SK

更新日期：1997-12-01 00:00:00

abstract：OBJECTIVE:An overdiagnosis bias occurs with the diagnosis of a disease that does not produce signs or symptoms before the patient dies from other causes. We sought to determine whether overdiagnosis bias is a factor when screening for squamous cell carcinoma of the lung. DESIGN:Retrospective study of the Miyagi Popula...

journal_title：Chest

authors： Sato M,Saito Y,Endo C,Sakurada A,Feller-Kopman D,Ernst A,Kondo T

更新日期：2004-07-01 00:00:00

abstract：:The pathogenesis and clinical manifestations of COPD are not restricted to pulmonary inflammation and structural remodeling. Rather, this disorder is associated with clinically significant systemic alterations in biochemistry and organ function. The systemic aspects of COPD include oxidative stress and altered circula...

journal_title：Chest

authors： Wouters EF,Creutzberg EC,Schols AM

更新日期：2002-05-01 00:00:00

abstract：:Seventy-two consecutive adult asthmatic patients seen in the Pulmonary Clinic at Rhode Island Hospital were tested for atopy by prick test with 14 standard aeroallergens and by in vitro total and specific IgE determinations (FAST). A total of 58.3 percent of patients were found to be atopic by these tests. There was a...

journal_title：Chest

authors： Kalliel JN,Goldstein BM,Braman SS,Settipane GA

更新日期：1989-12-01 00:00:00

abstract：:The definition of a standard therapy for resectable esophageal cancer remains a clinical controversy. In the past decade, a variety of strategies have been developed in an attempt to improve local control and decrease the all too common problem of distant metastases. Preoperative treatment with radiotherapy or chemoth...

journal_title：Chest

authors： DeCamp MM Jr,Swanson SJ,Jaklitsch MT

更新日期：1999-12-01 00:00:00

abstract：:The idea of inhaling smoke from cigarettes is historically new, actually less than a century old. Consumption of tobacco has changed from chewing tobacco and pipe smoking to smoking cigarettes; smokeless tobaccos are growing tremendously in popularity. The modern smoker is confronted with a highly engineered, complex ...

journal_title：Chest

authors： McCusker K

更新日期：1988-02-01 00:00:00

abstract：:A study of 26 men with bronchogenic cancer demonstrated high serum calcitonin levels in 62 percent (16). Levels were particularly high in patients with small-cell cancer and adenocarcinoma. Two varieties of hypercalcitonemia have been encountered: (1) ectopic hypercalcitonemia, in which the hormone is secreted by the ...

journal_title：Chest

authors： Silva OL,Becker KL,Primack A,Doppman JL,Snider RH

更新日期：1976-04-01 00:00:00

abstract：:Pulmonary hypertension and related pulmonary vascular diseases cause significant morbidities and high mortality and present many unique challenges toward improving outcomes in neonates, infants, and children. Differences between pediatric and adult disease are reflected in controversies regarding etiologies, classific...

journal_title：Chest

authors： Hopper RK,Abman SH,Ivy DD

更新日期：2016-07-01 00:00:00

abstract：:This study compared the nutritional status of patients with emphysema and chronic bronchitis and examined the relationship between lung dysfunction and nutritional depletion in patients with emphysema. There was no evidence of nutritional depletion in patients with chronic bronchitis (n = 4). In contrast, patients wit...

journal_title：Chest

authors： Openbrier DR,Irwin MM,Rogers RM,Gottlieb GP,Dauber JH,Van Thiel DH,Pennock BE

更新日期：1983-01-01 00:00:00

abstract：:Three patients had angiographic appearance of chronic primary coronary artery dissection with features that differed from other patients with this entity studied at autopsy; they were men, greater than or equal to 40 years of age, had angina pectoris and severe coronary artery disease. The right coronary artery, which...

journal_title：Chest

authors： Iskandrian AS,Bemis CE,Kimbiris D,Mintz GS,Hakki AH

更新日期：1985-02-01 00:00:00

abstract：:Hemodynamic and metabolic effects of methylprednisolone were investigated in a double-blind study of 28 patients with acute myocardial infarction (AMI), confirmed by unequivocal electrocardiographic and enzyme changes. Measurements were performed prior to and at 1.5, 3, 4, 4.5, 12 and 24 hours following infusion of me...

journal_title：Chest

authors： Henning RJ,Becker H,Vincent JL,Thijs L,Kalter E,Weil MH

更新日期：1981-02-01 00:00:00

abstract：:We studied eleven patients during 14 attempts at weaning from mechanical ventilation to determine whether central ventilatory drive, measured as airway occlusion pressure 0.1 s after onset of inspiration (P 0.1), during spontaneous breathing before and during a brief hypercapnic challenge, could accurately predict the...

journal_title：Chest

authors： Montgomery AB,Holle RH,Neagley SR,Pierson DJ,Schoene RB

更新日期：1987-04-01 00:00:00

abstract：STUDY OBJECTIVES:Anastomotic leakage after esophagectomy is associated with high postoperative morbidity and mortality. The most important predisposing factors for anastomotic leaks are ischemia of the gastric conduit and low blood oxygen content. The aim of this study was to evaluate the influence of thoracic epidural...

journal_title：Chest

authors： Michelet P,D'Journo XB,Roch A,Papazian L,Ragni J,Thomas P,Auffray JP

更新日期：2005-11-01 00:00:00

abstract：:A case of acute and recrudescent melioidosis complicated by pericarditis and pericardial effusion is described. The potential for the appearance of future cases in the United States and the necessity for physicians to remain aware of this potential diagnosis are discussed. ...

journal_title：Chest

authors： Ruff MJ,Lamkin N Jr,Braun J,Barnwell P

更新日期：1976-02-01 00:00:00

abstract：OBJECTIVE:To determine the sensitivity of bacteriologic studies in pediatric pulmonary tuberculosis. PATIENTS AND METHODS:Between January 1988 and December 1996, 104 consecutive patients aged 0 to 18 years received a diagnosis of primary pulmonary tuberculosis at our institution. Demographic, clinical, laboratory, and...

journal_title：Chest

authors： Merino JM,Alvarez T,Marrero M,Ansó S,Elvira A,Iglesias G,González JB

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND:There is significant heterogeneity within the primary graft dysfunction (PGD) syndrome. We aimed to identify distinct grade 3 PGD phenotypes based on severity of lung dysfunction and patterns of resolution. METHODS:Subjects from the Lung Transplant Outcomes Group (LTOG) cohort study with grade 3 PGD within ...

journal_title：Chest

authors： Shah RJ,Diamond JM,Cantu E,Lee JC,Lederer DJ,Lama VN,Orens J,Weinacker A,Wilkes DS,Bhorade S,Wille KM,Ware LB,Palmer SM,Crespo M,Localio AR,Demissie E,Kawut SM,Bellamy SL,Christie JD

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:The prevalence of COPD is estimated to 4 to 14%. According to the Global Initiative for Chronic Obstructive Lung Disease guidelines, COPD is divided into four stages. Patients with stage IV disease (very severe) have FEV1 < 30% of predicted values and/or respiratory insufficiency. The few studies that exist ...

journal_title：Chest

authors： Stenfors N

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:We suspected, based on clinical experience, that the prevalence of both intracardiac and pulmonary arteriovenous malformations (PAVMs) is higher than previously reported in a healthy population when using modern ultrasound technology combined with a rigorous saline contrast echocardiogram (SCE) protocol. We ...

journal_title：Chest

authors： Woods TD,Harmann L,Purath T,Ramamurthy S,Subramanian S,Jackson S,Tarima S

更新日期：2010-08-01 00:00:00

abstract：STUDY OBJECTIVE:We assessed whether transpleural methods for diagnosing peripheral lung cancer, such as needle aspiration or tumor excision, affect relapse and prognosis, because these techniques have potential to spread malignant cells from the tumor. DESIGN:A retrospective study. SETTING:National referral hospital....

journal_title：Chest

authors： Sawabata N,Maeda H,Ohta M,Hayakawa M

更新日期：2001-11-01 00:00:00

abstract：CASE PRESENTATION:A 76-year-old nonsmoking woman visiting from Honduras for the last 6 months with no known medical history originally presented to the ED complaining of abdominal pain. While in the ED, an incidental right middle lobe collapse was found on CT abdomen scan. Review of systems was positive for a chronic p...

journal_title：Chest

authors： Henson T,Matayeva E,Chua W,Iqbal J

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:Bronchoscopy is a useful tool for the diagnosis of lesions near central airways; however, the diagnostic accuracy of these procedures for peripheral pulmonary lesions (PPLs) is a matter of ongoing debate. In this setting, electromagnetic navigation bronchoscopy (ENB) is a technique used to navigate and obtai...

journal_title：Chest

authors： Folch EE,Labarca G,Ospina-Delgado D,Kheir F,Majid A,Khandhar SJ,Mehta HJ,Jantz MA,Fernandez-Bussy S

更新日期：2020-10-01 00:00:00

abstract：STUDY OBJECTIVE:To identify the prognostic factors for pneumothorax in patients in the ICU. DESIGN:Retrospective cohort study. SETTING:ICU at a university-based teaching hospital. PATIENTS AND METHODS:Sixty patients developed pneumothoraces in the ICU during a period of 36 months. Medical records relating to patient...

journal_title：Chest

authors： Chen KY,Jerng JS,Liao WY,Ding LW,Kuo LC,Wang JY,Yang PC

更新日期：2002-08-01 00:00:00

abstract：:We describe the Ca2+ movements in smooth muscle cells at rest and during activation and relaxation as deduced from transplasmalemmal Ca2+ fluxes and contractile respnses. The general picture which emerges is: the resting cell has a [Ca2+]cyt below 10(-7) M and large gradients are poised across both the cell membrane a...

journal_title：Chest

authors： van Breemen C,Aaronson P,Loutzenhiser R,Meisheri K

更新日期：1980-07-01 00:00:00

abstract：:Investigators have validated an abbreviated protocol for testing nonspecific bronchial reactivity with methacholine. We performed a similar validation study with histamine, another bronchoprovocative agent known to induce airflow obstruction. Histamine is pharmacologically distinct from methacholine and, under some ci...

journal_title：Chest

authors： Schmidt LE,Thorne PS,Watt JL,Schwartz DA

更新日期：1992-01-01 00:00:00

abstract：STUDY OBJECTIVES:Transbronchial lung biopsy (TBLB) during flexible bronchoscopy (FB) is the recommended procedure for diagnosing sarcoidosis in most cases, although its yield in stage I disease is reported to be not as high as when parenchymal involvement is radiologically evident. We undertook this study to assess the...

journal_title：Chest

authors： Trisolini R,Lazzari Agli L,Cancellieri A,Poletti V,Tinelli C,Baruzzi G,Patelli M

更新日期：2003-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Thirty to 50% of all COPD patients experience tissue wasting that may be caused by hypermetabolism, but the cause of the perturbed metabolic state is unclear. We hypothesized that the elevated O2 cost of ventilation (O2 COV) may be a contributing factor. All of the data are presented as means ...

journal_title：Chest

authors： Mannix ET,Manfredi F,Farber MO

更新日期：1999-03-01 00:00:00

abstract：OBJECTIVES:A fixed combination of long-acting beta(2)-agonists (LABA) plus inhaled corticosteroids (ICS) has never been proven to reduce asthma exacerbations vs ICS alone in children. This 12-month, double-blind, randomized study in 341 children (age range, 4 to 11 years) with asthma uncontrolled on ICS investigated wh...

journal_title：Chest

authors： Bisgaard H,Le Roux P,Bjåmer D,Dymek A,Vermeulen JH,Hultquist C

更新日期：2006-12-01 00:00:00

abstract：:The narcotic antagonists naloxone and naltrexone were used as respiratory stimulants in two patients failing traditional medical therapy for COPD. Both patients demonstrated improvement while receiving the drugs, but developed respiratory failure when they were discontinued abruptly. In selected patients with COPD, na...

journal_title：Chest

authors： Reents SB,Beck CA Jr

更新日期：1988-01-01 00:00:00

abstract：OBJECTIVE:The epigenetic basis for human asthma is not well studied, particularly among older adults. This study investigated the methylation profiles in sputum DNA among older adults with asthma, using a population of smokers. METHODS:This was a cross-sectional study using the Lovelace Smokers Cohort, a population of...

journal_title：Chest

authors： Sood A,Petersen H,Blanchette CM,Meek P,Picchi MA,Belinsky SA,Tesfaigzi Y

更新日期：2012-08-01 00:00:00