Persistent Challenges in Pediatric Pulmonary Hypertension.

abstract：:Fifty-nine patients were studied who had severe tricuspid regurgitation which was confirmed by right ventriculography and during surgery in order to determine the incidence of clinical, radiologic, and hemodynamic clues of severe tricuspid regurgitation. Eighty-eight percent of patients had Carvallo sign alone or in c...

journal_title：Chest

authors： Cha SD,Desai RS,Gooch AS,Maranhao V,Goldberg H

更新日期：1982-12-01 00:00:00

abstract：:A 75-year-old man with a history of resected colon carcinoma presented to his primary care physician because of a new onset of coughing. The patient had expectorated a small piece of solid tissue; pathologic examination of the tissue found it to be consistent with metastatic colon adenocarcinoma. After further work-up...

journal_title：Chest

authors： Zias EA,Owen RP,Borczuk A,Reichel J,Frater RW

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Obesity hypoventilation syndrome (OHS) conventionally includes awake hypercapnia, but an isolated raised bicarbonate, even in the absence of awake hypercapnia, may represent evidence of "early" OHS. We investigated whether such individuals exhibit certain features characteristic of established OHS. METHODS:...

journal_title：Chest

authors： Manuel ARG,Hart N,Stradling JR

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:The benefits of inhaled corticosteroids in the management of COPD are less apparent than they are in asthma therapy, and the potential for adverse systemic effects of high-dose inhaled corticosteroids has been recognized recently. It is therefore essential to know the maximal obtainable benefits in order to ...

journal_title：Chest

authors： Nishimura K,Koyama H,Ikeda A,Tsukino M,Hajiro T,Mishima M,Izumi T

更新日期：1999-01-01 00:00:00

abstract：:Alterations in peripheral vascular tone are presumed to contribute to circulatory failure during severe sepsis. Decreased venous tone with venous pooling may decrease effective circulatory blood volume, while decreased arterial tone with redistribution of systemic blood may compromise tissue nutrient flow. We compared...

journal_title：Chest

authors： Astiz ME,Rackow EC,Haydon P,Karras G,Weil MH

更新日期：1989-08-01 00:00:00

abstract：BACKGROUND:Pulmonary hypertension (PH) is a well-recognized complication of COPD. The impact of PH on exercise tolerance is largely unknown. We evaluated and compared the circulatory and ventilatory profiles during exercise in patients with COPD without PH, with moderate PH, and with severe PH. METHODS:Forty-seven pat...

journal_title：Chest

authors： Boerrigter BG,Bogaard HJ,Trip P,Groepenhoff H,Rietema H,Holverda S,Boonstra A,Postmus PE,Westerhof N,Vonk-Noordegraaf A

更新日期：2012-11-01 00:00:00

abstract：:Invasive thymoma recently has been shown to be sensitive to combination chemotherapy and in some cases to be relatively indolent. Two cases of extensive thymoma which responded to primary treatment with a combination of a platinum compound (carboplatin or cisplatin), doxorubicin (Adriamycin), and cyclophosphamide (or ...

journal_title：Chest

authors： Lara PN Jr,Bonomi PD,Faber LP

更新日期：1996-10-01 00:00:00

abstract：OBJECTIVES:Though numerous studies have demonstrated the short-term efficacy of lung volume reduction surgery (LVRS) in select patients with emphysema, the longer-term follow-up studies are just being reported. The primary objectives of this study were to assess long-term health-related quality of life, satisfaction, p...

journal_title：Chest

authors： Yusen RD,Lefrak SS,Gierada DS,Davis GE,Meyers BF,Patterson GA,Cooper JD

更新日期：2003-04-01 00:00:00

abstract：:Respiratory manifestations of systemic lupus erythematosus (SLE) are frequent. They include respiratory muscle abnormalities, which have been implicated in the pathogenesis of the "shrinking lung syndrome" (SLS). We report the case of a patient with this syndrome, in whom diaphragmatic paralysis due to demyelinating p...

journal_title：Chest

authors： Hardy K,Herry I,Attali V,Cadranel J,Similowski T

更新日期：2001-04-01 00:00:00

abstract：:Tobacco smoking during pregnancy is the most important modifiable risk factor for adverse pregnancy outcomes and long-term health complications for mother and baby. Tobacco use during pregnancy has decreased in high-income countries but not in Indigenous women in Australia, New Zealand, the United States, and Canada. ...

journal_title：Chest

authors： Gould GS,Lim LL,Mattes J

更新日期：2017-10-01 00:00:00

abstract：:Cystic fibrosis is the most common fatal inherited disease of Caucasians. At present, cystic fibrosis accounts for most cases of chronic progressive pulmonary disease and for many other clinical features in the first three decades of life. Thus, it is a challenge to both pediatricians and internists, particularly ches...

journal_title：Chest

authors： Davis PB,di Sant'Agnese PA

更新日期：1984-06-01 00:00:00

abstract：:We retrospectively studied the acute toxicity of corticosteroid therapy in 23 episodes of PCP occurring in the setting of AIDS and determined the incidence of HIV-related complications following these and 16 other contemporaneous episodes of AIDS-related PCP treated with antimicrobials alone. The mean duration of cort...

journal_title：Chest

authors： Lambertus MW,Goetz MB,Murthy AR,Mathisen GE

更新日期：1990-07-01 00:00:00

abstract：BACKGROUND:Acute care nurse practitioners (ACNPs) are increasingly being employed in ICUs to offset physician shortages, but no data exist about outcomes of critically ill patients continuously cared for by ACNPs. METHODS:Prospective cohort study of all admissions to an adult medical ICU in an academic, tertiary-care ...

journal_title：Chest

authors： Landsperger JS,Semler MW,Wang L,Byrne DW,Wheeler AP

更新日期：2016-05-01 00:00:00

abstract：PURPOSE:This study attempts to determine the distribution of transudates vs exudates in pathologically proved malignant pleural effusions and the necessity for cytologic studies in patients with a transudative effusion. MATERIALS AND METHODS:A retrospective review of all cytologically positive malignant pleural effusi...

journal_title：Chest

authors： Assi Z,Caruso JL,Herndon J,Patz EF Jr

更新日期：1998-05-01 00:00:00

abstract：:beta 2-agonist bronchodilators delivered by metered-dose inhalers (MDI) are commonly used in the treatment of bronchospasm in both intubated and nonintubated patients. Substantial data support the effectiveness of MDI delivery systems in nonintubated patients. However, few studies have examined the effectiveness of MD...

journal_title：Chest

authors： Manthous CA,Chatila W,Schmidt GA,Hall JB

更新日期：1995-01-01 00:00:00

abstract：:We report a patient in whom presumed vasospasm of an angiographically normal coronary artery led to severe transmural myocardial ischemia. To our knowledge, this is the first case in which an allergic reaction to locally applied chlorhexidine caused such a severe reaction. ...

journal_title：Chest

authors： Conraads VM,Jorens PG,Ebo DG,Claeys MJ,Bosmans JM,Vrints CJ

更新日期：1998-05-01 00:00:00

abstract：:Fatal pulmonary embolism (PE) is a major cause of mortality in patients with spinal cord injury. In order to ascertain those characteristics that might predict this event, we reviewed the records of all patients with autopsy-proven massive PE admitted to a regional spinal cord care center over a 5-year period. The inf...

journal_title：Chest

authors： Green D,Twardowski P,Wei R,Rademaker AW

更新日期：1994-03-01 00:00:00

abstract：BACKGROUND:We investigated whether artificial neural networks (ANNs) could diagnose pathology of lymph nodes by feeding B-mode images from convex-type echobronchoscopy to ANNs. METHODS:Subjects comprised 91 patients who had undergone endobronchial ultrasonography transbronchial needle aspiration at our hospital betwee...

journal_title：Chest

authors： Tagaya R,Kurimoto N,Osada H,Kobayashi A

更新日期：2008-01-01 00:00:00

abstract：:A newborn infant with severe respiratory distress from bilateral diaphragmatic paralysis caused by birth injury was successfully treated with nasal continuous positive airway pressure (CPAP). Improvement gradually occurred, and CPAP was discontinued after he was 23 days of age. This therapy has advantages over alterna...

journal_title：Chest

authors： Zajkowski EJ,Kravath RE

更新日期：1979-03-01 00:00:00

abstract：:We studied 15 nonsmoking, clinically stable asthmatic subjects aged 27 to 39 years to evaluate the potential cardiotoxic effects of combined use of a beta-adrenergic agonist drug and theophylline in the treatment of asthma. Subjects underwent a one-week washout period followed by two one-week periods of study receivin...

journal_title：Chest

authors： Coleman JJ,Vollmer WM,Barker AF,Schultz GE,Buist AS

更新日期：1986-07-01 00:00:00

abstract：STUDY OBJECTIVE:Lung transplantation is now available for patients with cystic fibrosis (CF) and end-stage lung disease. While pulmonary graft function is often considered the major priority following transplantation, the nonpulmonary complications of this systemic disease also continue. We examined the GI complication...

journal_title：Chest

authors： Gilljam M,Chaparro C,Tullis E,Chan C,Keshavjee S,Hutcheon M

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:To determine the risk of acquiring ventilator-associated pneumonia (VAP) and the impact on costs when extending ventilator circuit change intervals beyond 2 days to 7 and 30 days. DESIGN:Prospective 4-year review of mechanically ventilated patients. SETTING:The respiratory and medical ICUs of an 800-bed ter...

journal_title：Chest

authors： Fink JB,Krause SA,Barrett L,Schaaff D,Alex CG

更新日期：1998-02-01 00:00:00

abstract：PURPOSE:Stenosis and occlusion rates of internal mammary artery (IMA) and saphenous vein (SV) coronary artery bypass grafts (CABGs) are markedly different, which result from respective disparities in vascular remodeling. Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) regulate vascu...

journal_title：Chest

authors： Anstadt MP,Franga DL,Portik-Dobos V,Pennathur A,Bannan M,Mawulawde K,Ergul A

更新日期：2004-05-01 00:00:00

abstract：OBJECTIVE:To assess pulmonologists' use, training in the use, and knowledge base of the drug cyclophosphamide. DESIGN:Survey through questionnaire. Testing of knowledge base before and after instructional conference. PARTICIPANTS AND METHODS:Pulmonologists (94 attendings, 31 fellows), selected randomly at the 1996 an...

journal_title：Chest

authors： Cozzi PJ,Hall JB

更新日期：1999-11-01 00:00:00

abstract：:We have assessed right and left ventricular function by multigated radionuclide ventriculography in 12 consecutive patients with acquired immunodeficiency syndrome (AIDS) grouped according to the CDC classification system for HIV infection. Results were correlated with clinical, electrocardiographic and echocardiograp...

journal_title：Chest

authors： Raffanti SP,Chiaramida AJ,Sen P,Wright P,Middleton JR,Chiaramida S

更新日期：1988-03-01 00:00:00

abstract：:Lung scans with technetium sulfur colloid were performed in ten patients with life-threatening hemoptysis and nondiagnostic chest roentgenograms. Localized deposition of radionuclide was demonstrated in five of the six patients who were studied during active bleeding. These abnormalities were confirmed bronchoscopical...

journal_title：Chest

authors： Haponik EF,Rothfeld B,Britt EJ,Bleecker ER

更新日期：1984-08-01 00:00:00

abstract：BACKGROUND:Interest in airways inflammatory disease has increasingly focused on innate immunity. We investigated several components of innate immunity in induced sputum of patients with cystic fibrosis (CF), COPD, and asthma, and healthy control subjects. METHODS:Twenty eight patients with mild CF lung disease (age > ...

journal_title：Chest

authors： Xiao W,Hsu YP,Ishizaka A,Kirikae T,Moss RB

更新日期：2005-10-01 00:00:00

abstract：:Four patients with elevated creatine phosphokinase (CPK) values and recurrent chest pain were found to have thoracic outlet syndrome. This association of abnormal CPK levels and chest pain due to thoracic outlet syndrome has not been previously reported. Symptoms and CPK values improved with anti-inflammatory medicati...

journal_title：Chest

authors： Godfrey NF,Halter DG,Minna DA,Weiss M,Lorber A

更新日期：1983-03-01 00:00:00

abstract：:The field of lung transplant has made significant advances over the last several decades. Despite these advances, morbidity and mortality remain high when compared with other solid organ transplants. As the field moves forward, the speed by which progress can be made will in part be determined by our ability to overco...

journal_title：Chest

authors： Young KA,Dilling DF

更新日期：2019-03-01 00:00:00

abstract：:The effects of one hour exposures of healthy nonsmoking human volunteers to submicrometer H2SO4 droplets via nasal mask on tracheobronchial mucociliary particle clearance were studied using two different sized monodisperse gamma-tagged Fe2O3 test aerosols. The larger sized Fe2O3 aerosol, 7.5 micrometers AMAD, was depo...

journal_title：Chest

authors： Lippmann M,Leikauf G,Spektor D,Schlesinger RB,Albert RE

更新日期：1981-12-01 00:00:00