Retreatment of recurrent invasive thymoma with platinum, doxorubicin, and cyclophosphamide.

abstract：:The call for meaningful patient and family engagement in research has recently gained considerable momentum. This article defines patient and family engagement broadly and specifically in clinical research. Using a multicenter, North American weaning trial as an exemplar, we describe our early experiences as clinical ...

journal_title：Chest

authors： Burns KEA,Devlin JW,Hill NS

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:COPD is characterized by chronic inflammation. In vitro and ex vivo observations suggest that this inflammatory response is partially resistant to the effect of corticosteroids and that low-dose theophylline can restore this response via enhancement of histone deacetylase (HDAC) activity. Whether this occurs...

journal_title：Chest

authors： Cosío BG,Shafiek H,Iglesias A,Yanez A,Córdova R,Palou A,Rodriguez-Roisin R,Peces-Barba G,Pascual S,Gea J,Sibila O,Barnes PJ,Agusti A

更新日期：2016-07-01 00:00:00

abstract：:We report the clinical history, laboratory findings, and imaging features of coronavirus disease 2019 (COVID-19) in a neonate whose mother was also a patient. The newborn was the youngest patient with COVID-19 in the world at the time he was diagnosed. This case has brought more attention and understanding to the epid...

journal_title：Chest

authors： Xiong Y,Zhang Q,Zhao L,Shao J,Zhu W

更新日期：2020-07-01 00:00:00

abstract：:Following an outline that details the pathogens causing community-acquired pneumonia (CAP) identified in studies from Europe, this article reviews the guidelines for the management of CAP in four European countries--France, Italy, Spain, and the United Kingdom. The method behind the development of each document is des...

journal_title：Chest

authors： Woodhead M

更新日期：1998-03-01 00:00:00

abstract：:The risk and benefits of three treatment strategies were examined in 64 consecutive patients with acute myocardial infarction and cardiogenic shock. Thirteen patients received thrombolytic therapy (group 1), 29 patients received intra-aortic balloon pump counterpulsation support (group 2), and 22 patients were treated...

journal_title：Chest

authors： Stomel RJ,Rasak M,Bates ER

更新日期：1994-04-01 00:00:00

abstract：:Over the last few years, there has been a renewed interest in patients with characteristics of both asthma and COPD. Although the precise definition of asthma-COPD overlap (ACO) is still controversial, patients with overlapping features are frequently encountered in clinical practice, and may indeed have worse clinica...

journal_title：Chest

authors： Maselli DJ,Hardin M,Christenson SA,Hanania NA,Hersh CP,Adams SG,Anzueto A,Peters JI,Han MK,Martinez FJ

更新日期：2019-01-01 00:00:00

abstract：:Administration of tubocurarine, pancuronium, gallamine, or decamethonium into the cisterna magna of chloralosed dogs induced a rise in blood pressure. Clonidine (3 micrograms/kg) administered into the cisterna magna after tubocurarine, pancuronium, or gallamine significantly increased blood pressure; no significant ch...

journal_title：Chest

authors： Tsoucaris-Kupfer D,Schmitt H

更新日期：1983-02-01 00:00:00

abstract：PURPOSES:To determine the diagnostic accuracy of ultrasound in the diagnosis of pneumothorax in patients with COPD with particular regard to false-positive diagnoses. MATERIALS AND METHODS:This was a single-center, prospective, blinded study. Nine patients with pneumothorax, 9 patients with cystic fibrosis, 17 patient...

journal_title：Chest

authors： Slater A,Goodwin M,Anderson KE,Gleeson FV

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:Identification of sleep-disordered breathing (SDB) using questionnaires is critical from a clinical and research perspective. However, which questions to use and how well such questionnaires perform has thus far been fraught with substantial uncertainty. We aimed at delineating the usefulness of a set of que...

journal_title：Chest

authors： Spruyt K,Gozal D

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Pulmonary disease due to Mycobacterium avium complex (MAC-PD) radiographically resembles that due to tuberculosis; it preferentially affects elderly white men with predisposing pulmonary disorders (PDPD). METHODS:Twenty-nine patients with MAC-PD were identified from a community-based population, and the med...

journal_title：Chest

authors： Reich JM,Johnson RE

更新日期：1992-06-01 00:00:00

abstract：:Pure posterior mediastinal cystic lymphangiomas are very rare and have seldom been documented. This is the report of such a case, including the ultrasonographic and computed tomographic manifestations of the lesion, the first documentation of such manifestations in the literature. ...

journal_title：Chest

authors： Murayama S

更新日期：1985-12-01 00:00:00

abstract：:99mTechnetium macroaggregated albumin has successfully been used to define severe postoperative pulmonary vasoconstriction in a four-month-old boy with D-transposition of the great vessels who had undergone a Blalock-Hanlon surgical atrial septectomy. Radionuclide imaging documented clinically suspected pulmonary vaso...

journal_title：Chest

authors： Moodie DS,Levy JM,Kahn DR,Lieberman LM,Pastakia B

更新日期：1979-09-01 00:00:00

abstract：STUDY OBJECTIVES:To determine the usefulness of radioaerosol ventilation scans for the detection and localization of air leaks from the lungs or bronchial tree. DESIGN:Selected patients with suspected air leaks underwent ventilation scans. Retrospective analysis of data was carried out. SETTING AND PATIENTS:Twenty-ei...

journal_title：Chest

authors： Mark JB,McDougall IR

更新日期：1997-02-01 00:00:00

abstract：STUDY OBJECTIVES:The management of stable patients with COPD depends on the severity of symptoms and airflow limitation. Regarding inflammation, corticosteroids are the only medications that are recommended for use, and only under restricted circumstances. Corticosteroids tend to undertreat or overtreat patients with C...

journal_title：Chest

authors： Perng DW,Huang HY,Chen HM,Lee YC,Perng RP

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:Central sleep apnea (CSA) is common among patients with heart failure (HF) and is promoted by elevated CO2 chemosensitivity. Left atrial size is a marker of the hemodynamic severity of HF. The aim of this study was to determine if left atrial size predicts chemosensitivity to CO2 and CSA in patients with HF....

journal_title：Chest

authors： Calvin AD,Somers VK,Johnson BD,Scott CG,Olson LJ

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Exhaled breath temperature (EBT) is a new noninvasive method for the study of inflammatory respiratory diseases with a potential to reach clinical practice. However, few studies are available regarding the validation of this method, and they were mainly derived from small, pediatric populations; thus, the ra...

journal_title：Chest

authors： Carpagnano GE,Foschino-Barbaro MP,Crocetta C,Lacedonia D,Saliani V,Zoppo LD,Barnes PJ

更新日期：2017-04-01 00:00:00

abstract：:A young man presented to us with an asymptomatic ovoid mass which appeared to be in the right major fissure. The roentgenographic appearance of the lesion was that of a pseudotumor. The computerized tomography scan suggested tissue density leading to exploration. At surgery, we found the mass to be a portion of liver ...

journal_title：Chest

authors： Fanta CH,Kacoyanis GP,Koster JK Jr,McFadden ER Jr

更新日期：1980-08-01 00:00:00

abstract：:Continuous measurement of mixed venous oxygen saturation (SvO2) has been suggested as an adjunct in monitoring critically ill patients. We evaluated SvO2 monitoring in 24 patients suffering from complicated myocardial infarctions. Cardiac output and arterial lactate levels were measured when there were persistent 5 pe...

journal_title：Chest

authors： Kyff JV,Vaughn S,Yang SC,Raheja R,Puri VK

更新日期：1989-03-01 00:00:00

abstract：AIMS:This study investigated whether right ventricular (RV) diastolic function is impaired in pulmonary hypertension (PH) patients, and whether it is related to RV mass and afterload. In addition, the effects of an acute reduction of RV afterload by the oral intake of sildenafil were studied. Finally, we assessed wheth...

journal_title：Chest

authors： Gan CT,Holverda S,Marcus JT,Paulus WJ,Marques KM,Bronzwaer JG,Twisk JW,Boonstra A,Postmus PE,Vonk-Noordegraaf A

更新日期：2007-07-01 00:00:00

abstract：:Hemodynamic and oxygen transport effects of PGE1 were observed in the early postoperative period before development of ARDS in two series of general surgical patients with circulatory deficiencies. The first was a series of 19 studies in 18 patients, the second was a placebo-controlled series of 20 patients (ten recei...

journal_title：Chest

authors： Appel PL,Shoemaker WC,Kram HB

更新日期：1991-04-01 00:00:00

abstract：BACKGROUND:The presence of aerobic Gram-negative bacilli (AGNB) in the oropharynx can be either temporary or persistent. Prolonged colonization (ie, carriage) is distinguished from transient presence (ie, acquisition), which often occurs in healthy individuals but less frequently in those with underlying disease. Preva...

journal_title：Chest

authors： Mobbs KJ,van Saene HK,Sunderland D,Davies PD

更新日期：1999-06-01 00:00:00

abstract：:Portopulmonary hypertension (PPHTN) is an uncommon complication of advanced liver disease. Epoprostenol has been effective in the treatment of PPHTN and has been used as a bridge to orthotopic liver transplantation (OLT). The role of OLT in the reversal of PPHTN is unclear. We report a case of severe PPHTN (mean pulmo...

journal_title：Chest

authors： Rafanan AL,Maurer J,Mehta AC,Schilz R

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:In addition to affecting the oxygen supply to the brain, pulmonary function is a marker of multiple insults throughout life (including smoking, illness, and socioeconomic deprivation). In this meta-analysis of existing longitudinal studies, the hypothesis that lower pulmonary function and respiratory illness...

journal_title：Chest

authors： Russ TC,Kivimäki M,Batty GD

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Dynamic hyperinflation (DH) develops in patients with COPD during incremental exercise with a cycle ergometer. The aims of this study were to determine whether DH can be evidenced after walking with a handheld spirometer and to determine its functional consequences. METHODS:Fifty patients with COPD (39 men;...

journal_title：Chest

authors： Callens E,Graba S,Gillet-Juvin K,Essalhi M,Bidaud-Chevalier B,Peiffer C,Mahut B,Delclaux C

更新日期：2009-12-01 00:00:00

abstract：OBJECTIVE:To investigate the associations of maternal and grandmaternal smoking before, during, and after pregnancy with childhood asthma. DESIGN, SETTING, AND PARTICIPANTS:We conducted a case-control study nested within the Children's Health Study in southern California. The case patients consisted of 338 children wi...

journal_title：Chest

authors： Li YF,Langholz B,Salam MT,Gilliland FD

更新日期：2005-04-01 00:00:00

abstract：STUDY OBJECTIVES:We report on the long-term safety and efficacy of bosentan treatment in patients with pulmonary arterial hypertension (PAH). BACKGROUND:In a preceding study, bosentan was well tolerated and significantly improved the exercise capacity and hemodynamics of patients with PAH after 12 weeks of treatment. ...

journal_title：Chest

authors： Sitbon O,Badesch DB,Channick RN,Frost A,Robbins IM,Simonneau G,Tapson VF,Rubin LJ

更新日期：2003-07-01 00:00:00

abstract：:The spectrum of pathogens and the microbiologic investigations used to obtain a diagnosis in 178 patients with severe pneumonia (88 percent requiring intermittent positive-pressure ventilation) are reviewed. Ninety-five patients had primary pneumonia, 31 had nosocomial pneumonia, 24 were immunocompromised patients, an...

journal_title：Chest

authors： Potgieter PD,Hammond JM

更新日期：1992-01-01 00:00:00

abstract：:Based on the theory that obstructive (OSA) and central (CSA) sleep apneas share common pathophysiologic mechanisms, we attempted to treat eight patients with predominantly CSA by continuous positive airway pressure (CPAP). All patients exhibited repetitive episodes of CSA and mixed sleep apneas (MSA) in the supine pos...

journal_title：Chest

authors： Issa FG,Sullivan CE

更新日期：1986-08-01 00:00:00

abstract：STUDY OBJECTIVES:To measure the prevalence of exercise-induced bronchospasm (EIB) and to determine its effect on the physical performance response to training in otherwise healthy young adults. DESIGN:Observational, retrospective study. SETTING:Fort Jackson, SC, May to July 1998. PARTICIPANTS:One hundred thirty-seve...

journal_title：Chest

authors： Sonna LA,Angel KC,Sharp MA,Knapik JJ,Patton JF,Lilly CM

更新日期：2001-06-01 00:00:00

abstract：STUDY OBJECTIVE:Immune and inflammatory mechanisms could play a significant role in pulmonary arterial hypertension (PAH) genesis or progression, especially in patients with connective tissue diseases. Immunosuppressive therapy should be better evaluated in this setting. STUDY DESIGN:Monocentric retrospective study. ...

journal_title：Chest

authors： Sanchez O,Sitbon O,Jaïs X,Simonneau G,Humbert M

更新日期：2006-07-01 00:00:00