Abstract:
:Administration of tubocurarine, pancuronium, gallamine, or decamethonium into the cisterna magna of chloralosed dogs induced a rise in blood pressure. Clonidine (3 micrograms/kg) administered into the cisterna magna after tubocurarine, pancuronium, or gallamine significantly increased blood pressure; no significant change was found after decamethonium. The pressor response to clonidine after tubocurarine was antagonized by injection of the alpha 1-adrenoceptor-blocking agents AR-C 239 or prazosin into the cisterna magna at low doses prior to injection of clonidine. Yohimbine, a preferential alpha 2-adrenoceptor-blocking agent was ineffective. It is suggested that the pressor response to intracisternal clonidine after intracisternal tubocurarine is due to stimulation of alpha 1-adrenoceptor stimulation.
journal_name
Chestjournal_title
Chestauthors
Tsoucaris-Kupfer D,Schmitt Hdoi
10.1378/chest.83.2_supplement.349subject
Has Abstractpub_date
1983-02-01 00:00:00pages
349-51issue
2 Suppleissn
0012-3692issn
1931-3543pii
S0012-3692(15)40031-5journal_volume
83pub_type
杂志文章相关文献
CHEST文献大全abstract::We report the findings in two patients with sulfasalazine-induced pulmonary disease. The first patient developed pulmonary interstitial fibrosis after more than 4 yr of treatment for Crohn's disease. Pulmonary symptoms and chest roentgenographic and pulmonary function abnormalities gradually reversed after stopping th...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.101.4.1033
更新日期:1992-04-01 00:00:00
abstract::The contemporary surgical repertoire for the evaluation and treatment of patients with lung cancer includes the bronchoscope, mediastinoscope, thoracoscope, and standard surgical instrumentation. The recent advances in video optics and the development of endoscopic instruments have significantly expanded the surgical ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.107.6_supplement.298s
更新日期:1995-06-01 00:00:00
abstract:BACKGROUND:Pulmonary arterial hypertension (PAH) is a rare disease with a predilection for young women that is associated with right ventricular failure and premature death. PAH can complicate pregnancy with hemodynamic instability or sudden death during parturition and postpartum. Our aim was to examine the impact of ...
journal_title:Chest
pub_type: 杂志文章,多中心研究
doi:10.1378/chest.12-0528
更新日期:2013-05-01 00:00:00
abstract:STUDY OBJECTIVE:In the present study, we evaluated the leukocyte esterase (LE) area of a reagent strip designed for urinalysis for the semiquantitative measurement of the percentage of polymorphonuclear neutrophils (PMNs) in BAL fluid. DESIGN:Prospective. The relative PMN counts (obtained by conventional microscopy an...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.118.5.1450
更新日期:2000-11-01 00:00:00
abstract::Cystic fibrosis is the most common fatal inherited disease of Caucasians. At present, cystic fibrosis accounts for most cases of chronic progressive pulmonary disease and for many other clinical features in the first three decades of life. Thus, it is a challenge to both pediatricians and internists, particularly ches...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1016/s0012-3692(16)62421-2
更新日期:1984-06-01 00:00:00
abstract::The problem of inner-city asthma, as studied in Chicago, IL, is introduced. Chicago has a high incidence of asthma, but prevalence, morbidity, and mortality rates vary by neighborhood and are highest in neighborhoods with the lowest socioeconomic status. Efforts in Chicago to mitigate these gaps have been extraordinar...
journal_title:Chest
pub_type:
doi:10.1378/chest.07-1929
更新日期:2007-11-01 00:00:00
abstract::Endoscopic lung volume-reduction therapy for emphysema has been associated with therapeutic responses smaller in magnitude and less durable than surgical volume reduction (LVRS). Bronchoscopic emphysematous lung sealant (ELS) therapy has been shown to produce improvements in pulmonary function similar to surgery at 1 ...
journal_title:Chest
pub_type: 临床试验,杂志文章
doi:10.1378/chest.13-0446
更新日期:2013-11-01 00:00:00
abstract::Extrapulmonary tuberculosis refers to Mycobacterium tuberculosis involving organs other than the lungs (eg, pleura, lymph nodes, genitourinary tract, abdomen, skin, joints and bones, or meninges). In non-HIV-endemic areas, where reactivation is the predominant mechanism of tuberculosis, pleural involvement occurs in 4...
journal_title:Chest
pub_type: 杂志文章
doi:10.1016/j.chest.2016.02.655
更新日期:2016-10-01 00:00:00
abstract::We report three cases of organophosphate (OP) poisoning. One patient was a 19-year-old woman who drank OP compounds in an attempt at suicide. The other two patients became intoxicated on the way to the hospital during mouth-to-mouth breathing. The first patient died in the emergency department, and the other two were ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.122.2.740
更新日期:2002-08-01 00:00:00
abstract::The history of the use of beta-blockers for congestive heart failure, beginning with the innovative seminal study by the Swedish group in 1975 to studies in 1995, is reviewed and shows that almost all trials favored the use of beta-blockers. They tended to demonstrate an increase in ejection fraction, a decrease in le...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1378/chest.113.3.800
更新日期:1998-03-01 00:00:00
abstract::Severe head injury often results in hypoxemia, but the pathophysiology of this phenomenon is unclear. We studied 24 patients hospitalized after severe head injury to determine whether the abnormality of oxygen transfer as measured by venous admixture (Qs/Qt) was associated with a reduction in functional residual capac...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.84.1.29
更新日期:1983-07-01 00:00:00
abstract::This report describes a patient who developed pulmonary hypertension 6 years after lung transplantation for primary pulmonary hypertension (PPH). Evaluation with right heart catheterization followed by pulmonary angiography, however, demonstrated that the pulmonary hypertension was secondary to an anastomotic narrowin...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.116.2.564
更新日期:1999-08-01 00:00:00
abstract:BACKGROUND:We sought to determine the impact of OSA syndrome (OSAS) on symptoms and quality of life (QoL) among patients with posttraumatic stress disorder (PTSD). In addition, we assessed adherence and response to positive airway pressure (PAP) therapy in this population. METHODS:This was a case-controlled observatio...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.15-0693
更新日期:2016-02-01 00:00:00
abstract::OSA is a common yet underdiagnosed disorder encountered in everyday practice. The disease is a unique physiologic stressor that contributes to the development or progression of many other disorders, particularly cardiovascular conditions. The pulmonary circulation is specifically affected by the intermittent hypoxic a...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1378/chest.14-0614
更新日期:2015-03-01 00:00:00
abstract::Spontaneous pneumomediastinum is an uncommon benign condition that is occasionally associated with air within the spinal canal. We describe a further case in a 14-year-old girl and suggest a classification system based on a detailed review of the previous literature. Forty-eight patients with spontaneous pneumomediast...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1378/chest.09-0514
更新日期:2010-05-01 00:00:00
abstract:OBJECTIVE:The improved lung deposition of hydrofluoroalkane-134a beclomethasone dipropionate (HFA-BDP) extrafine aerosol compared with chlorofluorocarbon beclomethasone dipropionate (CFC-BDP) suggests that lower doses of HFA-BDP may be required to provide equivalent asthma control. The present study was undertaken to t...
journal_title:Chest
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1378/chest.115.2.343
更新日期:1999-02-01 00:00:00
abstract::A 64-year-old patient was admitted to the hospital with a history of two syncopal episodes. The results of the physical examination, resting electrocardiogram and His-bundle study were all normal. Study with a 24-hour ECG monitor (Holter) was at first interpreted as demonstrating periods of sinus arrest. However, more...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.68.4.582
更新日期:1975-10-01 00:00:00
abstract::Important alterations in respiratory function have been observed after open cholecystectomy. These include a decrease in the abdominal tidal volume, forced vital capacity, and forced expiratory volume at 1 s. Laparoscopic cholecystectomy is a new procedure allowing removal of the gallbladder without a subcostal or mid...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.103.4.1173
更新日期:1993-04-01 00:00:00
abstract::Several reports have implicated pregnancy as a cause of deterioration in patients with pulmonary arteriovenous fistulas. We report a 27-year-old woman with multiple pulmonary arteriovenous fistulas who required coil spring embolotherapy in her 24th week of pregnancy due to a spontaneous hemothorax and hypoxemia. ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.98.6.1522
更新日期:1990-12-01 00:00:00
abstract::Pulmonary embolism (PE) is a common disorder that is accompanied by significant morbidity and mortality. Although anticoagulation is the standard treatment for PE, thrombolytic therapy, with its ability to produce rapid clot lysis, has long been considered an attractive alternative. Although many studies have been per...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1378/chest.115.6.1695
更新日期:1999-06-01 00:00:00
abstract::Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and usually fatal disease, based on a multifaceted and incompletely understood pathogenesis. Some of the cellular and molecular mechanisms of vascular remodeling have been experimentally explored, and it is obvious that alterations of microvessels are invo...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1378/chest.11-1962
更新日期:2012-07-01 00:00:00
abstract:BACKGROUND:Previous studies have shown "beat-to-beat" variation in systemic BP with high-frequency jet ventilation (HFJV). However, it is not clear if such changes are paralleled by changes in cardiac output. OBJECTIVE:To characterize the effect of HFJV near or equal to the heart rate (HR) on beat-to-beat cardiac outp...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1378/chest.112.6.1600
更新日期:1997-12-01 00:00:00
abstract::The hypothetic benefit of CPAP on cardiac performance and on a reduction in VO2 was tested in a patient before heart transplantation after acute myocardial infarction using continuous SvO2 monitoring. The CPAP added to inotropic support (enoximone plus dobutamine) and intraaortic balloon pumping dramatically increased...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.99.2.512
更新日期:1991-02-01 00:00:00
abstract:BACKGROUND:Balloon pulmonary angioplasty (BPA) in chronic thromboembolic pulmonary hypertension (CTEPH) improves hemodynamics and exercise capacity. However, its effect on respiratory function is unclear. Our objective was to investigate the effect of BPA on respiratory function. METHODS:We enrolled patients with inop...
journal_title:Chest
pub_type: 杂志文章
doi:10.1016/j.chest.2016.10.002
更新日期:2017-03-01 00:00:00
abstract::Cytomegaloviral infection presenting in an immunologically compromised host as a solitary pulmonary nodule has not previously been reported. A patient with a renal transplant and with no pulmonary symptoms was noted to have a single nodule on a chest roentgenogram. At autopsy, this proved to be secondary to cytomegalo...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.71.2.220
更新日期:1977-02-01 00:00:00
abstract:BACKGROUND:The majority of community-acquired pneumonia (CAP) patients (about 80%) will be treated as outpatients, because therapy with a single agent will work. For the remaining 20% of patients requiring hospitalization, there is some growing debate regarding the efficacy of different management approaches. For hospi...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1378/chest.128.2.940
更新日期:2005-08-01 00:00:00
abstract::We prospectively evaluated nine patients with cough from postnasal drip for evidence of extrathoracic upper airway obstruction. Patients compared before treatment to normal control subjects had physiologic evidence of extrathoracic upper airway obstruction; their mean FIF50%/FEF50% and FIF25-75%/FEF25-75% ratios of 0....
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.85.3.346
更新日期:1984-03-01 00:00:00
abstract::Echocardiographic examination in a patient with primary pulmonary hypertension demonstrated midsystolic closure of the aortic valve, which has often been described in hypertrophic cardiomyopathy with or without obstruction, in discrete subaortic stenosis, and in ruptured aneurysm of the right coronary sinus of Valsalv...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.79.6.710
更新日期:1981-06-01 00:00:00
abstract::A patient with unruptured congenital aneurysm of the left coronary sinus of Valsalva presented with acute right-sided heart failure due to right ventricular outflow tract obstruction. The mechanism for such an acute presentation may have been a sudden increase in the size of the aneurysm. The surgical importance of th...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.101.2.578
更新日期:1992-02-01 00:00:00
abstract::Symptoms consistent with hypersensitivity pneumonitis (HP) occurred in 26 of 50 employees working in a localized area of a large factory. This area was served by a single heating-cooling unit utilizing a water humidification system. The illness consisted of flu-like symptoms with fever, chills, headache, cough, dyspne...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.77.2.183
更新日期:1980-02-01 00:00:00