Bilateral phrenic paralysis in a patient with systemic lupus erythematosus.

Abstract:

:Respiratory manifestations of systemic lupus erythematosus (SLE) are frequent. They include respiratory muscle abnormalities, which have been implicated in the pathogenesis of the "shrinking lung syndrome" (SLS). We report the case of a patient with this syndrome, in whom diaphragmatic paralysis due to demyelinating phrenic lesions was diagnosed at the same time as SLE. Follow-up studies showed a favorable clinical and diaphragmatic outcome with corticosteroid therapy, but little change in spirometry. It is concluded that severe diaphragm palsy is possibly due to phrenic nerve lesions in SLE, and that the link between diaphragm dysfunction and the SLS is probably not a straightforward one.

journal_name

Chest

journal_title

Chest

authors

Hardy K,Herry I,Attali V,Cadranel J,Similowski T

doi

10.1378/chest.119.4.1274

subject

Has Abstract

pub_date

2001-04-01 00:00:00

pages

1274-7

issue

4

eissn

0012-3692

issn

1931-3543

pii

S0012-3692(15)52091-6

journal_volume

119

pub_type

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