Sleep Duration and Efficiency Associated With Better Functional Exercise Capacity in Black Smokers at Risk for COPD.

Abstract:

BACKGROUND:Black smokers have earlier development of lung disease as well as poorer sleep health than whites. RESEARCH QUESTION:In a sample of black smokers, to what extent does sleep health modify the association between smoking level and functional exercise capacity? DESIGN AND METHODS:Cross-sectional data from 209 black smokers (≥ 1 cigarette in last month), aged 40 to 65 years with no evidence of sleep-disordered breathing (apnea-hypopnea index < 15) or severe COPD (FEV1 > 50%), were used for the current study. Self-reported smoking rate, objectively measured sleep efficiency (SE), total sleep time (TST), and the 6-min walk test (6MWT) for functional exercise capacity were the key assessments. RESULTS:The mean age was 54.8 years (SD, 5.96), and mean cigarettes smoked per day (cpd) was 8.71 (SD, 6.78). Mean SE was 69.9% (SD, 12.3%), and mean TST was 307.99 min (SD 92.2). In adjusted linear regression models of the 6MWT (meters), TST (slope estimate, -0.14; P = .14) and SE (slope estimate, -1.0; P = .19) were negatively associated with 6MWT. The smoking rate × SE interaction was highly significant (slope estimate, 0.18; P = .007) such that in individuals who smoked ≥ 10 cpd, every additional percentage of SE garnered an additional distance of 0.83 to 6.62 m. Similarly, the smoking rate × TST interaction was significant (slope estimate, 0.019; P = .03) such that in smokers who smoked ≥ 10 cpd, every additional minute of TST garnered an additional distance of 0.04 to 0.60 m. INTERPRETATION:Higher SE and, to a lesser extent, longer TST, in black adults who smoke ≥ 10 cpd is associated with better 6MWT performance. CLINICAL TRIAL REGISTRATION:ClinicalTrials.gov; No.: NCT03534076; URL: www.clinicaltrials.gov.

journal_name

Chest

journal_title

Chest

authors

Gangemi AJ,Satti A,Zantah M,Blair R,Brewer B,Ma G,Grandner MA,Davey A,Criner GJ,Patterson F

doi

10.1016/j.chest.2020.03.070

subject

Has Abstract

pub_date

2020-10-01 00:00:00

pages

1680-1688

issue

4

eissn

0012-3692

issn

1931-3543

pii

S0012-3692(20)30749-2

journal_volume

158

pub_type

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