A technique for isolated airway segment lavage.

Abstract:

:A novel technique has been developed for the isolation and lavaging of a central airway segment in humans. The procedure uses a double-balloon airway-sampling catheter that is placed into the airways with fiberoptic bronchoscopic guidance. A protocol using this technique was attempted in 32 subjects (18 normal subjects and 14 subjects with mild asthma), and 27 of the subjects were able to complete all phases of the protocol, including bronchoalveolar lavage and lavage of an isolated airway segment. There was no significant complication in any subject. Cellular composition of the lavages demonstrated differences in cell differential and total cell counts for the two different sampled regions (central airway vs alveolar spaces). We believe that this technique of lavage of an isolated airway segment is safe and has potential usefulness in many areas of pulmonary research.

journal_name

Chest

journal_title

Chest

authors

Eschenbacher WL,Gravelyn TR

doi

10.1378/chest.92.1.105

subject

Has Abstract

pub_date

1987-07-01 00:00:00

pages

105-9

issue

1

eissn

0012-3692

issn

1931-3543

pii

S0012-3692(16)37647-4

journal_volume

92

pub_type

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