Abstract:
:The aim of this study was to investigate whether the demonstration of plasma cells (PC), which are normally absent in bronchoalveolar lavage (BAL) fluid, facilitates differentiation among pulmonary disorders. Initial BAL fluid samples of 1,260 patients were analyzed. In 83 of these, PC were found. Of these 83, 47 were obtained from individuals suffering from extrinsic allergic alveolitis (EAA). The number of PC in BAL fluid from EAA patients was found related to the time between antigen exposure and BAL. Drug-induced pneumonitis appeared to be another disorder with a high percentage of cases with PC in the BAL fluid (35.7 percent). Therefore, we conclude that determination of PC in BAL fluid has differential diagnostic value in discriminating among interstitial lung diseases of various origins. However, the exact role of BAL fluid and PC and the link to clinical manifestations of these diseases needs further investigation.
journal_name
Chestjournal_title
Chestauthors
Drent M,van Velzen-Blad H,Diamant M,Wagenaar SS,Donckerwolck-Bogaert M,van den Bosch JMdoi
10.1378/chest.103.6.1720subject
Has Abstractpub_date
1993-06-01 00:00:00pages
1720-4issue
6eissn
0012-3692issn
1931-3543pii
S0012-3692(15)42069-0journal_volume
103pub_type
杂志文章相关文献
CHEST文献大全abstract::It is known that smoking affects the development and maintenance of certain types of granulomatous lung diseases. To explore this mechanism(s), we measured tumor necrosis factor (TNF)-alpha concentrations in the culture supernatants of lipopolysaccharide (LPS)-stimulated alveolar macrophages (AMs) in 13 healthy nonsmo...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.103.2.479
更新日期:1993-02-01 00:00:00
abstract::Because of an emphasis on patient safety and recognition of the effectiveness of simulation as an educational modality across multiple medical specialties, use of health-care simulation (HCS) for medical education has become more prevalent. In this article, the effectiveness of simulation for areas important to the pr...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1016/j.chest.2019.07.011
更新日期:2019-12-01 00:00:00
abstract::Patients presenting with partial atrioventricular septal (PAVC) defects in adulthood are rare. Eight adult patients with this congenital heart defect who had surgical repair are described, along with their long-term postoperative follow-up data. Average age at operation was 48 years, and average follow-up was 13.4 yea...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.94.2.321
更新日期:1988-08-01 00:00:00
abstract:BACKGROUND:Guidelines are critical for facilitating cost-effective COPD care. Development and implementation in low-and middle-income countries (LMICs) is challenging. To guide future strategy, an overview of current global COPD guidelines is required. RESEARCH QUESTION:We systematically reviewed national COPD guideli...
journal_title:Chest
pub_type: 杂志文章
doi:10.1016/j.chest.2020.09.260
更新日期:2020-10-08 00:00:00
abstract::A 42-year-old woman with an anomalous left coronary artery originating from the pulmonary artery and a fistula from the left coronary artery to the left ventricle was treated by aortocoronary bypass grafting of an autologous saphenous vein. The presence of an abundant collateral circulation and of fistulous communicat...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.74.1.102
更新日期:1978-07-01 00:00:00
abstract::Proximal pulmonary artery aneurysms (PAAs) are rare. Most are associated with secondary pulmonary hypertension or a variety of rare systemic disorders. An asymptomatic adult patient presented with bilateral hilar enlargement on a routine chest roentgenogram. Computed tomography of the chest revealed 5 cm bilateral pro...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.102.1.311
更新日期:1992-07-01 00:00:00
abstract:BACKGROUND:Interest in airways inflammatory disease has increasingly focused on innate immunity. We investigated several components of innate immunity in induced sputum of patients with cystic fibrosis (CF), COPD, and asthma, and healthy control subjects. METHODS:Twenty eight patients with mild CF lung disease (age > ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.128.4.2316
更新日期:2005-10-01 00:00:00
abstract::Before and after percutaneous transvenous mitral commissurotomy (PTMC), pulmonary function studies were performed in 25 patients with mitral stenosis, in order to determine the effects of pulmonary hemodynamics on pulmonary function in patients with mitral stenosis. After PTMC, dramatic improvements in pulmonary hemod...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.98.2.290
更新日期:1990-08-01 00:00:00
abstract:OBJECTIVES:To review our experience with thoracoscopy and talc poudrage during the previous 15 years with regards to efficacy, side effects, morbidity, and mortality. METHODS:Six hundred fourteen consecutive patients (58.6% female; mean age, 54.5 years) underwent thoracoscopy with talc poudrage from August 1983 to May...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.119.3.801
更新日期:2001-03-01 00:00:00
abstract::Subjective assessment of the respiratory rate and the adequacy of tidal ventilation are the oldest and most widely practiced forms of respiratory monitoring in critically ill patients. Surprisingly, this method of assessment has itself never been evaluated in patients. The estimation of tidal volume in nine patients w...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.87.5.577
更新日期:1985-05-01 00:00:00
abstract:STUDY OBJECTIVES:To examine the effect of patient body mass index (BMI) on outcome in intensive care. DESIGN:In a prospective study, the patients were classified into groups based on the calculated BMI, as follows: BMI < 19.0 (n = 350), > or = 19.0 and < 25.0 (n = 663), > or = 25.0 and < 29.9 (n = 585), > or = 30.0 an...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.127.6.2125
更新日期:2005-06-01 00:00:00
abstract:STUDY OBJECTIVE:To evaluate the importance of fluid balance and changes in extravascular lung water (EVLW) on survival in the ICU and short-term outcome in patients with pulmonary edema. DESIGN:Retrospective analysis of data (sorting by survival and "treatment received") from a recent randomized controlled trial of fl...
journal_title:Chest
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1378/chest.100.4.1068
更新日期:1991-10-01 00:00:00
abstract:BACKGROUND:Venous thromboembolism (VTE) remains a major cause of morbidity following stroke. The optimal form of pharmacologic prophylaxis following stroke is unknown. METHODS:We identified randomized trials comparing unfractionated heparin (UFH) to low-molecular-weight heparin (LMWH) for VTE prevention in ischemic st...
journal_title:Chest
pub_type: 杂志文章,meta分析
doi:10.1378/chest.07-1826
更新日期:2008-01-01 00:00:00
abstract::Heterozygous familial type II hyperlipoproteinemia (F type II) is primarily manifested in hypercholesterolemia (due to low density lipoprotein-cholesterol [LDL-C] elevation) and premature coronary heart disease (CHD). We studied sequentially the effects of low cholesterol-low saturated fat-low simple carbohydrate diet...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.79.3.286
更新日期:1981-03-01 00:00:00
abstract:STUDY OBJECTIVES:To describe the prevalence of parental prompting to smoke (eg, parent requests that their child light the parent's cigarette in his/her own mouth) in a sample of families, and to assess the agreement between child and parent reports of the prompting behaviors. DESIGN, SETTING, AND PARTICIPANTS:A total...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.125.2.429
更新日期:2004-02-01 00:00:00
abstract:BACKGROUND:The use of infrared thermometry to measure temperatures in hospitalized patients is increasing. Although infrared thermometers have been proven to be accurate when they are used by well-trained personnel, no previous studies have examined their accuracy during routine hospital use. OBJECTIVE:To determine th...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.115.4.1002
更新日期:1999-04-01 00:00:00
abstract::Angiosarcoma in the lung is an uncommon disorder and is usually attributable to metastasis from a primary site. Primary pulmonary angiosarcoma is extremely rare, and the prognosis of affected individuals is dismal, with most patients dying within months of presentation. Indeed, there have been no reported instances of...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.124.6.2397
更新日期:2003-12-01 00:00:00
abstract::A new bronchoscopic-protected catheter brush (BPCB), designed to obtain uncontaminated bronchial secretions, was studied in vitro and in vivo. The device was composed of a standard biopsy brush, protected by a single catheter and occluded with an agar plug. Ejection of the plug was obtained neither by advancing the br...
journal_title:Chest
pub_type: 临床试验,杂志文章
doi:10.1378/chest.93.4.746
更新日期:1988-04-01 00:00:00
abstract::In most studies, many statistical tests are performed. They can be run to compare the groups at baseline, look at relationships among the various measures, and, for intervention trials, examine more than one end point. As the number of tests increases, so does the probability of finding at least one of them to be stat...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1378/chest.11-0523
更新日期:2011-07-01 00:00:00
abstract:STUDY OBJECTIVES:To determine attitudes and knowledge about sleep medicine among chest physicians. DESIGN:: Interactive survey of self-selected respondents. SETTING:Interactive session at the 1998 American College of Chest Physicians (ACCP) annual meeting. PARTICIPANTS:Approximately 60 chest physicians. INTERVENTIO...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.117.6.1603
更新日期:2000-06-01 00:00:00
abstract::Lymphoid interstitial pneumonia (LIP) is regarded as both a disease and a nonneoplastic, inflammatory pulmonary reaction to various external stimuli or systemic diseases. It is an uncommon condition with incidence and prevalence rates that are largely unknown. Liebow and Carrington originally classified LIP as an idio...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1378/chest.122.6.2150
更新日期:2002-12-01 00:00:00
abstract::An asymptomatic cremator was found incidentally to have lymphocytic alveolitis by bronchoalveolar lavage, and the basis for this finding was investigated. No known causes of lymphocyte alveolitis including sarcoidosis, hypersensitivity pneumonitis, berylliosis, tuberculosis, or fungal diseases of the lung were found. ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.105.2.617
更新日期:1994-02-01 00:00:00
abstract:BACKGROUND:Disease-specific patient-reported outcome (PRO) instruments are important in assessing the impact of disease and treatment. The Pulmonary Arterial Hypertension-Symptoms and Impact Questionnaire is the first instrument for quantifying pulmonary arterial hypertension (PAH) symptoms and impacts developed accord...
journal_title:Chest
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1016/j.chest.2018.04.027
更新日期:2018-10-01 00:00:00
abstract:BACKGROUND:While the beneficial effect of exercise capacity on mortality is well-accepted, its effect on health-care costs remains uncertain. This study investigates the relationship between exercise capacity and health-care costs. METHODS:The Veterans Affairs Health Care System recently implemented a Decision Support...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.126.2.608
更新日期:2004-08-01 00:00:00
abstract::Histopathologic and morphometric studies of small pulmonary arteries were performed in 16 cases of secundum atrial septal defect (ASD) and severe pulmonary hypertension. Besides typical plexogenic arteriopathies found in six cases, organized microthrombi and what we call "musculoelastosis," that is, proliferation of l...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.89.5.694
更新日期:1986-05-01 00:00:00
abstract:BACKGROUND:Identification of sleep-disordered breathing (SDB) using questionnaires is critical from a clinical and research perspective. However, which questions to use and how well such questionnaires perform has thus far been fraught with substantial uncertainty. We aimed at delineating the usefulness of a set of que...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.11-3164
更新日期:2012-12-01 00:00:00
abstract::A case of acute tuberculous pneumonia diagnosed by transbronchial biopsy is presented. We postulate that the unusually rapid progression was due to an exudative hypersensitivity reaction to aspirated tuberculoprotein. ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.71.6.774
更新日期:1977-06-01 00:00:00
abstract:UNLABELLED:STUDY OBJECTIVES AND DESIGN: Health-related quality of life (QoL) instruments are generally used for studies of asthma in specialized settings. For primary care use, there is a need for brief and simple questionnaires for structured patient-reported outcomes. We validated the Mini-Asthma Quality of Life Ques...
journal_title:Chest
pub_type: 杂志文章,多中心研究
doi:10.1378/chest.129.4.925
更新日期:2006-04-01 00:00:00
abstract:STUDY OBJECTIVES:Cardiac surgery with cardiopulmonary bypass (CPB) is associated with major inflammatory triggers that cause marked activation of the microcirculation. This inflammatory response is associated with significant organ dysfunction. How this response causes organ dysfunction is not well understood; conseque...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.128.1.229
更新日期:2005-07-01 00:00:00
abstract::A woman with a history of bilateral mastectomy and silicone implants for fibrocystic disease and a history of atrial septal defect repair presented with pleural nodules on a chest radiograph. A thorascopic biopsy performed for possible mesothelioma demonstrated chronic inflammation and focal pleural fibrosis due to a ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.127.5.1854
更新日期:2005-05-01 00:00:00