Pulmonary vascular disease in secundum atrial septal defect with pulmonary hypertension.

abstract：BACKGROUND:The protein deacetylase sirtuin-1 (SIRT1) is an antiaging molecule that is decreased in the lung in patients with COPD. Recently, SIRT1 was reported to be detectable in serum, but serum SIRT1 (s120S) levels have not yet been reported in patients with COPD. METHODS:Serum SIRT1 protein of all samples was meas...

journal_title：Chest

authors： Yanagisawa S,Papaioannou AI,Papaporfyriou A,Baker JR,Vuppusetty C,Loukides S,Barnes PJ,Ito K

更新日期：2017-08-01 00:00:00

abstract：:Myocardial ischemia results in altered left ventricular (LV) diastolic compliance, reflected by an abnormal mitral inflow pattern on Doppler echocardiography. To investigate the relationship of Doppler echocardiography and regional myocardial systolic function during dipyridamole infusion, we evaluated transmitral flo...

journal_title：Chest

authors： Lattanzi F,Picano E,Masini M,De Prisco F,Distante A,L'Abbate A

更新日期：1989-05-01 00:00:00

abstract：:The history holds the central role in distinguishing among asthma, chronic bronchitis, and emphysema. A personal or family history of atopy, a history of seasonal worsening of disease in response to a known environmental agent, perhaps seasonal, and marked variability in the severity of airflow obstruction, often with...

journal_title：Chest

authors： Snider GL

更新日期：1985-01-01 00:00:00

abstract：OBJECTIVES:Immunosuppressive pharmacologic agents prescribed to patients with diffuse interstitial and inflammatory lung disease and lung transplant recipients are associated with potential risks for adverse reactions. Strategies for minimizing such risks include administering these drugs according to established, safe...

journal_title：Chest

authors： Baughman RP,Meyer KC,Nathanson I,Angel L,Bhorade SM,Chan KM,Culver D,Harrod CG,Hayney MS,Highland KB,Limper AH,Patrick H,Strange C,Whelan T

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVES:To review our experience with thoracoscopy and talc poudrage during the previous 15 years with regards to efficacy, side effects, morbidity, and mortality. METHODS:Six hundred fourteen consecutive patients (58.6% female; mean age, 54.5 years) underwent thoracoscopy with talc poudrage from August 1983 to May...

journal_title：Chest

authors： de Campos JR,Vargas FS,de Campos Werebe E,Cardoso P,Teixeira LR,Jatene FB,Light RW

更新日期：2001-03-01 00:00:00

abstract：STUDY OBJECTIVES:Autopsy evaluation of tracheobronchomalacia (TBM) in patients with Duchenne muscular dystrophy (DMD) who were receiving long-term ventilation through uncuffed tracheostomies. DESIGN:Necropsies were performed in seven patients with DMD who had received positive-pressure ventilation through uncuffed tra...

journal_title：Chest

authors： Baydur A,Kanel G

更新日期：2003-04-01 00:00:00

abstract：BACKGROUND:Low-density gas mixtures and oxygen (O₂) supplementation are known to improve physical performance and ventilatory adaptation during incremental maximal exercise in COPD. We investigated whether their combined use during intense physical training is also effective in ameliorating exercise tolerance in patien...

journal_title：Chest

authors： Scorsone D,Bartolini S,Saporiti R,Braido F,Baroffio M,Pellegrino R,Brusasco V,Crimi E

更新日期：2010-11-01 00:00:00

abstract：:Combination chemotherapy has dramatically improved the prognosis of patients with intermediate and high grade histologic subtypes of non-Hodgkin's lymphomas. Treatment-related complications, however, are considerable, and a common problem encountered is respiratory distress or respiratory insufficiency. Usually these ...

journal_title：Chest

authors： Glenn LD,Armitage JO,Goldsmith JC,Sorensen S,Howe D,Weisenberger DD

更新日期：1988-09-01 00:00:00

abstract：:The advisability of prolonged oral or nasotracheal intubation is of continuing concern to physicians caring for patients requiring prolonged mechanical ventilatory assistance. Currently, in many health care centers, prolonged intubation is defined as being in excess of seven days. We treated a patient who required mec...

journal_title：Chest

authors： Vogelhut MM,Downs JB

更新日期：1979-07-01 00:00:00

abstract：:The cause of bleeding in a patient with recurrent massive hemoptysis was not apparent after bronchoscopy and gross examination of the lobectomy specimen. Histologic submission of all major bronchi uncovered dilated, tortuous bronchial arteries just below the bronchial mucosa with sites of both current and healing arte...

journal_title：Chest

authors： Spark RP,Sobonya RE,Armbruster RJ,Marco JD,Rotkis TC

更新日期：1991-02-01 00:00:00

abstract：BACKGROUND:Inadequate localized drug concentrations and systemic adverse effects are among the concerns when regional infections are treated with systemic antibiotics. We designed and fabricated a poly(D,L)-lactide-co-glycolide (PLGA)-based biodegradable drug delivery system and evaluated the release of antibiotics bot...

journal_title：Chest

authors： Liu KS,Liu SJ,Chen HY,Huang YK,Peng YJ,Wu RC,Ueng SW

更新日期：2012-05-01 00:00:00

abstract：:We investigated 654 subjects of a small Lombardy (Italy) town between 15 and 64 years of age who were representative of the general population. By clinical examination, the sample included 535 normal subjects (164 normal smokers, 341 normal nonsmokers, 30 normal subjects with acute upper respiratory illness within 30 ...

journal_title：Chest

authors： Cerveri I,Bruschi C,Zoia MC,Zanon P,Maccarini L,Grassi M,Rampulla C

更新日期：1988-01-01 00:00:00

abstract：:The most examined tumor markers in lung cancer patients are CEA, hormonal peptides, and some neurogenic enzymes in small cell carcinoma. Calcitonin, ACTH, ADH, CEA, neurophysin, oxytocin, beta-endorphin, neuron-specific enolase, and CK BB are elevated in serum specimens in 25-75% of cases of small cell carcinoma. The ...

journal_title：Chest

authors： Hansen M,Pedersen AG

更新日期：1986-04-01 00:00:00

abstract：:Some macrolides have been found to exert anti-inflammatory effects. Lung diseases such as asthma, panbronchiolitis, cystic fibrosis, and bronchiectasis are thought to respond to the immunomodulatory properties of macrolides. We report three cases of idiopathic bronchiolitis obliterans organizing pneumonia, now called ...

journal_title：Chest

authors： Stover DE,Mangino D

更新日期：2005-11-01 00:00:00

abstract：STUDY OBJECTIVES:(1) To describe a new percutaneous pleural biopsy technique to obtain multiple-site parietal pleural biopsy specimens in patients with pleural effusion (PE), and (2) to evaluate its effectiveness and safety compared to current techniques. DESIGN:Prospective interventional study. SETTING:University te...

journal_title：Chest

authors： Uthaman B,Behbehani N,Abal A,Madda J,Khan S

更新日期：2004-05-01 00:00:00

abstract：:Unresectable carcinoma of the lung has traditionally been recognized as a contraindication to surgery in massive hemoptysis. A 60-year-old man had massive hemoptysis. At surgery an unresectable neoplastic mass invading the mediastinum and great vessels was encountered. Subtotal resection was accomplished using a stapl...

journal_title：Chest

authors： Hargrove WC 3rd,Harken AH

更新日期：1979-08-01 00:00:00

abstract：:Bronchial stump fistula occurred on the seventh postoperative day in a 45-year-old man who underwent right pneumonectomy for T2N2M0 adenocarcinoma of the lung. It was attributable to ventilator-related barotrauma during treatment of ARDS from multiple pulmonary emboli. A frequently lethal complication, its presentatio...

journal_title：Chest

authors： Pomerantz AH,Derasari MD,Sethi SS,Khan S

更新日期：1988-03-01 00:00:00

abstract：BACKGROUND:To assess the factors associated with reintubation in patients who had successfully passed a spontaneous breathing trial. METHODS:We used logistic regression and recursive partitioning analyses of prospectively collected clinical data from adults admitted to ICUs of 37 hospitals in eight countries, who had ...

journal_title：Chest

authors： Frutos-Vivar F,Ferguson ND,Esteban A,Epstein SK,Arabi Y,Apezteguía C,González M,Hill NS,Nava S,D'Empaire G,Anzueto A

更新日期：2006-12-01 00:00:00

abstract：:The effect of smoking three cigarettes in rapid succession on maximal and partial expiratory flow rates was studied in ten healthy smokers. The mean decrease in maximal midexpiratory flow and partial midexpiratory and end-expiratory flow was statistically significant. The response was maximal after the first cigarette...

journal_title：Chest

authors： Hamosh P,Taveira Da Silva AM

更新日期：1977-11-01 00:00:00

abstract：BACKGROUND:Mepolizumab was the first licensed anti-IL5 monoclonal antibody for severe eosinophilic asthma (SEA). To date there are few data to confirm its efficacy in the real-world setting or assessment of baseline characteristics associated with response. RESEARCH QUESTION:How do patients with severe eosinophilic as...

journal_title：Chest

authors： Kavanagh JE,d'Ancona G,Elstad M,Green L,Fernandes M,Thomson L,Roxas C,Dhariwal J,Nanzer AM,Kent BD,Jackson DJ

更新日期：2020-08-01 00:00:00

abstract：:Acute bacterial endocarditis developed in a 65-year-old man two years after surgical resection of a false aneurysm of the left ventricle. The patient had cerebral embolic manifestations, and coagulase-positive Staphylococcus aureus was cultured from each of six blood samples. A pericardial friction rub and a changing ...

journal_title：Chest

authors： Pitlik S,Cohen L,Melamed R,Rosenfeld J

更新日期：1977-02-01 00:00:00

abstract：BACKGROUND:It has been postulated that right ventricular (RV) function may improve after lung volume reduction surgery (LVRS) for severe emphysema due to improvement in lung elastic recoil. Improved lung elastic recoil after LVRS is hypothesized to "tether" open extraalveolar vessels, thereby leading to a decrease in p...

journal_title：Chest

authors： Falk JA,Martin UJ,Scharf S,Criner GJ

更新日期：2007-11-01 00:00:00

abstract：:Forty-eight children with known asthma (ranging in age from 2 to 16 years) were studied during an acute attack. Each received either terbutaline or epinephrine subcutaneously in a random double-blind fashion. Measurement of heart rate, respiratory rate, and systemic arterial systolic and diastolic blood pressures and ...

journal_title：Chest

authors： Davis WJ,Pang LM,Chernack WJ,Mellins RB

更新日期：1977-11-01 00:00:00

abstract：:To investigate the influence of resting pulmonary mechanics on the pattern of breathing during exercise in chronic obstructive pulmonary disease (COPD), we studied 29 patients with moderate to severe COPD (FEV1 50 +/- 20 percent predicted), and 10 normal subjects. Lung mechanics were studied using esophageal balloon t...

journal_title：Chest

authors： Marin JM,Hussain SN,Gibbons WJ,Polverino M,Levy RD,Cosio MG

更新日期：1993-09-01 00:00:00

abstract：:The clinical course of congestive heart failure (CHF) and mitral valve stenosis (MVS) is accompanied by episodes of dyspnea, wheezing, and cough, symptoms also observed in patients with bronchial hyperreactivity. However, it is still controversial whether bronchial hyperreactivity is demonstrable in patients with chro...

journal_title：Chest

authors： Brunnée T,Graf K,Kastens B,Fleck E,Kunkel G

更新日期：1993-05-01 00:00:00

abstract：:We report a case of a 32-year-old woman who, after passage of broncholiths, developed a mediastinal abscess that required surgical drainage for treatment. Previously reported infectious complications resulting from broncholiths include obstructive pneumonitis and recurrent aspiration pneumonitis secondary to bronchoes...

journal_title：Chest

authors： Studer SM,Heitmiller RF,Terry PB

更新日期：2002-01-01 00:00:00

abstract：STUDY OBJECTIVES:To evaluate the risk factors associated with postoperative respiratory infection in patients undergoing lung cancer surgery, with special emphasis on the perioperative pattern of airway colonization. DESIGN:Prospective cohort study. SETTING:Department of Pneumology and Thoracic Surgery of a tertiary ...

journal_title：Chest

authors： Belda J,Cavalcanti M,Ferrer M,Serra M,Puig de la Bellacasa J,Canalis E,Torres A

更新日期：2005-09-01 00:00:00

abstract：:This report describes three cases of massive mobile right heart thrombus and reviews the available literature to better define the pathophysiology, natural history and most appropriate therapy of the syndrome. The clinical presentation of most patients has been severe cardiopulmonary dysfunction and the diagnosis has ...

journal_title：Chest

authors： Crowell RH,Adams GS,Koilpillai CJ,McNutt EJ,Montague TJ

更新日期：1988-12-01 00:00:00

abstract：BACKGROUND:Shared decision-making is an essential element of low-dose CT (LDCT) screening for lung cancer. Understanding patient-level outcomes from the National Lung Screening Trial (NLST) is critical to effectively communicate risks and benefits of screening to patients. METHODS:We performed a secondary analysis of ...

journal_title：Chest

authors： Iaccarino JM,Silvestri GA,Wiener RS

更新日期：2019-11-01 00:00:00

abstract：:Microbubble formation has been accepted as the mechanism producing contrast echoes. Comparisons of the contrast effects of various agents have been studied extensively, but the importance of gas-mixing has been less appreciated. To test the hypothesis that good gas-mixing, by facilitating microbubble formation, would ...

journal_title：Chest

authors： Chiang CW,Lin FC,Fu M,Fang BR,Hsu TS,Lee YS

更新日期：1986-05-01 00:00:00