Terbutaline in the treatment of acute asthma in childhood.

Abstract:

:Forty-eight children with known asthma (ranging in age from 2 to 16 years) were studied during an acute attack. Each received either terbutaline or epinephrine subcutaneously in a random double-blind fashion. Measurement of heart rate, respiratory rate, and systemic arterial systolic and diastolic blood pressures and careful clinical assessment of obstruction of the airway were made before and at 15, 30, and 60 minutes after the administration of the drugs. Appreciable and significant clinical improvement was noted in 19 of the 24 patients in both groups and was of comparable magnitude. A small, but significant, increase in heart rate was noted in those patients requiring only one injection of terbutaline, suggesting that the drug's selectivity for the lung is relative not absolute. The present study demonstrates that terbutaline is an effective bronchodilator drug in acute childhood asthma.

journal_name

Chest

journal_title

Chest

authors

Davis WJ,Pang LM,Chernack WJ,Mellins RB

doi

10.1378/chest.72.5.614

subject

Has Abstract

pub_date

1977-11-01 00:00:00

pages

614-7

issue

5

eissn

0012-3692

issn

1931-3543

pii

S0012-3692(16)38005-9

journal_volume

72

pub_type

临床试验,杂志文章,随机对照试验

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