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Gaps in COPD Guidelines of Low- and Middle-Income Countries: A Systematic Scoping Review.

Abstract：

BACKGROUND:Guidelines are critical for facilitating cost-effective COPD care. Development and implementation in low-and middle-income countries (LMICs) is challenging. To guide future strategy, an overview of current global COPD guidelines is required. RESEARCH QUESTION:We systematically reviewed national COPD guidelines, focusing on worldwide availability and identification of potential development, content, context, and quality gaps that may hamper effective implementation. STUDY DESIGN AND METHODS:Scoping review of national COPD management guidelines. We assessed: (1) global guideline coverage; (2) guideline information (authors, target audience, dissemination plans); (3) content (prevention, diagnosis, treatments); (4) ethical, legal, and socio-economic aspects; and (5) compliance with the eight Institute of Medicine (IOM) guideline standards. LMICs guidelines were compared with those from high-income countries (HICs). RESULTS:Of the 61 national COPD guidelines identified, 30 were from LMICs. Guidelines did not cover 1.93 billion (30.2%) people living in LMICs, whereas only 0.02 billion (1.9%) in HICs were without national guidelines. Compared with HICs, LMIC guidelines targeted fewer health-care professional groups and less often addressed case finding and co-morbidities. More than 90% of all guidelines included smoking cessation advice. Air pollution reduction strategies were less frequently mentioned in both LMICs (47%) and HICs (42%). LMIC guidelines fulfilled on average 3.37 (42%) of IOM standards, compared with 5.29 (66%) in HICs (P < .05). LMICs scored significantly lower compared with HICs regarding conflicts of interest management, updates, articulation of recommendations, and funding transparency (all, P < .05). INTERPRETATION:Several development, content, context, and quality gaps exist in COPD guidelines from LMICs that may hamper effective implementation. Overall, COPD guidelines in LMICs should be more widely available and should be transparently developed and updated. Guidelines may be further enhanced by better inclusion of local risk factors, case findings, and co-morbidity management, preferably tailored to available financial and staff resources.

journal_name

Chest

journal_title

Chest

authors

Tabyshova A,Hurst JR,Soriano JB,Checkley W,Wan-Chun Huang E,Trofor AC,Flores-Flores O,Alupo P,Gianella G,Ferdous T,Meharg D,Alison J,Correia de Sousa J,Postma MJ,Chavannes NH,van Boven JFM

doi

10.1016/j.chest.2020.09.260

subject

Has Abstract

pub_date

2020-10-08 00:00:00

eissn

0012-3692

issn

1931-3543

pii

S0012-3692(20)34869-8

pub_type

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Gaps in COPD Guidelines of Low- and Middle-Income Countries: A Systematic Scoping Review.