Esophagectomy after induction chemoradiation.

Abstract:

:The definition of a standard therapy for resectable esophageal cancer remains a clinical controversy. In the past decade, a variety of strategies have been developed in an attempt to improve local control and decrease the all too common problem of distant metastases. Preoperative treatment with radiotherapy or chemotherapy has been proved to be feasible, although neither strategy has resulted in improved survival rates. More recently, concurrent, neoadjuvant chemoradiation has been utilized with encouraging pathologic responses. Equally important is the recognition that such aggressive therapy does not lead to worse surgical outcomes. The evidence for the safety, feasibility, and efficacy of induction therapy followed by esophagectomy is presented in the context of developing a rational methodology to allow for the ongoing modification of standards of care in the management of this difficult disease.

journal_name

Chest

journal_title

Chest

authors

DeCamp MM Jr,Swanson SJ,Jaklitsch MT

doi

10.1378/chest.116.suppl_3.466s

subject

Has Abstract

pub_date

1999-12-01 00:00:00

pages

466S-469S

issue

6 Suppl

eissn

0012-3692

issn

1931-3543

pii

S0012-3692(15)30747-9

journal_volume

116

pub_type

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