Clinical challenges in pulmonary hypertension: Roger S. Mitchell lecture.

abstract：OBJECTIVE:To compare the short-term physiologic effects of mask pressure support ventilation (PSV) and proportional assist ventilation (PAV) in patients in clinically stable condition with chronic ventilatory failure (CVF). DESIGN:Randomized, controlled physiologic study. SETTING:Lung function units of two pulmonary ...

journal_title：Chest

authors： Porta R,Appendini L,Vitacca M,Bianchi L,Donner CF,Poggi R,Ambrosino N

更新日期：2002-08-01 00:00:00

abstract：:We report the findings in two patients with sulfasalazine-induced pulmonary disease. The first patient developed pulmonary interstitial fibrosis after more than 4 yr of treatment for Crohn's disease. Pulmonary symptoms and chest roentgenographic and pulmonary function abnormalities gradually reversed after stopping th...

journal_title：Chest

authors： Hamadeh MA,Atkinson J,Smith LJ

更新日期：1992-04-01 00:00:00

abstract：:The pulmonary status of 178 asymptomatic asthmatic children with normal time-volume spirograms was further evaluated using flow-volume loops, body plethysmographic studies, and blood gas tensions in arterialized capillary blood. Residual volume (RV) was abnormal in 26%, total lung capacity (TLC) in 33%, RV/TLC% in 41%...

journal_title：Chest

authors： Cooper DM,Cutz E,Levison H

更新日期：1977-03-01 00:00:00

abstract：:The differentiation of ventricular tachycardia from supraventricular conducted with aberration constitutes a perennial challenge. We report a new surface ECG clue, hitherto undescribed, the presence of which, during wide QRS tachycardia, indicates that the tachycardia in question is ventricular rather than supraventri...

journal_title：Chest

authors： Reddy GV,Leghari RU

更新日期：1987-10-01 00:00:00

abstract：:In patients at risk for sepsis after cardiac surgery, the efficacy of intravenous immunoglobulin (Ig) treatment was compared with a historical control population, equivalent in patient characteristics and disease severity. Using APACHE II scores, especially in the high-risk group (IgG), we could discriminate between l...

journal_title：Chest

authors： Pilz G,Kreuzer E,Kääb S,Appel R,Werdan K

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:Limited data are available on the impact of time to ICU admission and outcomes for patients with severe community acquired pneumonia (CAP). Our objective was to examine the association of time to ICU admission and 30-day mortality in patients with severe CAP. METHODS:A retrospective cohort study of 161 ICU ...

journal_title：Chest

authors： Restrepo MI,Mortensen EM,Rello J,Brody J,Anzueto A

更新日期：2010-03-01 00:00:00

abstract：:Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and usually fatal disease, based on a multifaceted and incompletely understood pathogenesis. Some of the cellular and molecular mechanisms of vascular remodeling have been experimentally explored, and it is obvious that alterations of microvessels are invo...

journal_title：Chest

authors： Hanumegowda C,Farkas L,Kolb M

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:The prevalence of COPD is estimated to 4 to 14%. According to the Global Initiative for Chronic Obstructive Lung Disease guidelines, COPD is divided into four stages. Patients with stage IV disease (very severe) have FEV1 < 30% of predicted values and/or respiratory insufficiency. The few studies that exist ...

journal_title：Chest

authors： Stenfors N

更新日期：2006-09-01 00:00:00

abstract：:Treatment failure (TF) is defined as a clinical condition with inadequate response to antimicrobial therapy. Clinical response should be evaluated within the first 72 h of treatment, whereas infiltrate images may take up to 6 weeks to resolve. Early failure is considered when ventilatory support and/or septic shock ap...

journal_title：Chest

authors： Menendez R,Torres A

更新日期：2007-10-01 00:00:00

abstract：:A prospective study was done to compare four different methods of securing oral endotracheal tubes: adhesive tape (A), Twill tape (T), Twill tape with FlexBlue bite block (TFXB), and Velcro tie with FlexBlue (VFXB), used on sequential days. Thirty-six patients were enrolled for 136 patient-days and 18 had complete 4-d...

journal_title：Chest

authors： Levy H,Griego L

更新日期：1993-11-01 00:00:00

abstract：:The measurement of the activity of acid hydrolases and of alkaline phosphatase in bronchial aspirates obtained through bronchoscopic procedures from a series of 300 patients forms the basis for a screening program to diagnose bronchial malignant neoplasms more effectively. We define such a screening test as one permit...

journal_title：Chest

authors： Kühn SH,de Kock MA,Gevers W

更新日期：1978-08-01 00:00:00

abstract：:Takayasu's arteritis is a vasculitis characterized by inflammation and obliteration of large- and medium-sized arteries and has not been previously associated with interstitial pulmonary fibrosis. A patient with Takayasu's arteritis was shown to have interstitial pulmonary fibrosis and mesangial glomerulonephritis, su...

journal_title：Chest

authors： Greene NB,Baughman RP,Kim CK

更新日期：1986-04-01 00:00:00

abstract：:Cardiac tamponade is a medical emergency that can be readily reversed with timely recognition and appropriate intervention. The clinical diagnosis of cardiac tamponade requires synthesis of a constellation of otherwise nonspecific features based on an understanding of the underlying pathophysiological characteristics....

journal_title：Chest

authors： Kearns MJ,Walley KR

更新日期：2018-05-01 00:00:00

abstract：:We describe two patients with AIDS who developed new diffuse pulmonary infiltrates during the course of their hospitalization. In both cases, the infiltrates were attributed to pulmonary hemorrhage complicating an existing condition rather than representing a new pulmonary process. Identification of pulmonary hemorrha...

journal_title：Chest

authors： Koziel H,Haley K,Nasser I,Filderman AE

更新日期：1994-12-01 00:00:00

abstract：:We present an unusual case of a patient with chronic hepatitis C who experienced dyspnea, fever, and cough after 2 1/2 months' treatment with interferon. His radiograph demonstrated diffuse pulmonary infiltrates and bronchoalveolar lavage fluid showed an increase in lymphocytes, especially CD8-positive cells. The lung...

journal_title：Chest

authors： Ogata K,Koga T,Yagawa K

更新日期：1994-08-01 00:00:00

abstract：RATIONALE:Pseudomonas aeruginosa lung infection in patients with bronchiectasis, a chronic airway disease that is characterized by episodes of exacerbation, is associated with more severe disease and a higher utilization of health-care resources. Inhaled tobramycin solution reduces the number of acute exacerbations in ...

journal_title：Chest

authors： Bilton D,Henig N,Morrissey B,Gotfried M

更新日期：2006-11-01 00:00:00

abstract：:Elevated endorphin levels in patients with COPD may act to diminish the sensation of dyspnea. Exogenous opioids decrease exertional dyspnea and increase exercise capacity in COPD patients. The purpose of this study was to determine the effects of endogenous opioids on the exercise capacity and control of breathing in ...

journal_title：Chest

authors： Kirsch JL,Muro JR,Stansbury DW,Fischer CE,Monfore R,Light RW

更新日期：1989-10-01 00:00:00

abstract：BACKGROUND:Bosentan, an oral endothelin (ET)-A/ET-B receptor antagonist, is effective in the treatment of pulmonary arterial hypertension. OBJECTIVE:To investigate the safety and efficacy of bosentan therapy in patients with inoperable chronic thromboembolic pulmonary hypertension (CTEPH). DESIGN:Case series. SETTIN...

journal_title：Chest

authors： Bonderman D,Nowotny R,Skoro-Sajer N,Jakowitsch J,Adlbrecht C,Klepetko W,Lang IM

更新日期：2005-10-01 00:00:00

abstract：:The authors believe this to be the first case report of atrial fibrillation following pulse methylprednisolone therapy in an adult. The literature regarding the complications of pulse methylprednisolone therapy is reviewed, with particular emphasis on the incidence and pathogenesis of arrhythmias. ...

journal_title：Chest

authors： McLuckie AE,Savage RW

更新日期：1993-08-01 00:00:00

abstract：BACKGROUND:There is a growing use of procalcitonin (PCT) to facilitate the diagnosis and management of severe sepsis. We investigated the impact of one to two PCT determinations on ICU day 1 on health-care utilization and cost in a large research database. METHODS:A retrospective, propensity score-matched multivariabl...

journal_title：Chest

authors： Balk RA,Kadri SS,Cao Z,Robinson SB,Lipkin C,Bozzette SA

更新日期：2017-01-01 00:00:00

abstract：STUDY OBJECTIVES:Sputum induction (SI) is a noninvasive tool for sampling inflamed airways. The purpose of this study was to determine the optimal duration of collection in patients with cystic fibrosis (CF). The hypothesis was that the duration of SI collection would quantitatively and qualitatively alter the content ...

journal_title：Chest

authors： Aitken ML,Greene KE,Tonelli MR,Burns JL,Emerson JC,Goss CH,Gibson RL

更新日期：2003-03-01 00:00:00

abstract：:The first report of coincident IHSS and ostium secundum ASD is corroborated and successful septal myotomy and myectomy with patch closure of the ASD is described. ...

journal_title：Chest

authors： Smith DC,Vieweg WV,Folkerth TL,Hagan AD

更新日期：1975-08-01 00:00:00

abstract：:Pancreaticopleural fistula secondary to chronic pancreatitis is a rare cause of recurrent pleural effusion. The demonstration of the fistula with endoscopic retrograde pancreatography and CT is invasive or limited. We report in two patients the use of magnetic resonance pancreatography as a noninvasive alternative to ...

journal_title：Chest

authors： Materne R,Vranckx P,Pauls C,Coche EE,Deprez P,Van Beers BE

更新日期：2000-03-01 00:00:00

abstract：STUDY OBJECTIVE:To determine the effect of a symptom-based and a peak flow-based action plan in preventing acute exacerbations in subjects with poorly controlled asthma. DESIGN:A randomized controlled trial in which subjects who had required urgent treatment for their asthma were allocated to receive no action plan, a...

journal_title：Chest

authors： Cowie RL,Revitt SG,Underwood MF,Field SK

更新日期：1997-12-01 00:00:00

abstract：:We wanted to determine the efficacy of dobutamine infusions and Prbc transfusions on splanchnic tissue oxygen utilization by measuring gastric pHi. Physiologic parameters and pHi measurements via the use of a gastric tonometer were obtained in 21 septic patients before and after the administration of a dobutamine infu...

journal_title：Chest

authors： Silverman HJ,Tuma P

更新日期：1992-07-01 00:00:00

abstract：:Before and after percutaneous transvenous mitral commissurotomy (PTMC), pulmonary function studies were performed in 25 patients with mitral stenosis, in order to determine the effects of pulmonary hemodynamics on pulmonary function in patients with mitral stenosis. After PTMC, dramatic improvements in pulmonary hemod...

journal_title：Chest

authors： Yoshioka T,Nakanishi N,Okubo S,Kunieda T,Ishikura F,Nagata S

更新日期：1990-08-01 00:00:00

abstract：:Liposarcoma is rare in children and rarely occurs in the posterior mediastinum in any age group. A massive intrathoracic tumor in a 17-year-old young man was a diagnostic dilemma; preoperative radiographic evaluation and biopsy led us to believe it was a teratoma. At operation, a poorly differentiated myxoid liposarco...

journal_title：Chest

authors： Mikkilineni RS,Bhat S,Cheng AW,Prevosti LG

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND:Tranexamic acid (TA) is an antifibrinolytic drug currently used systemically to control bleeding. To date, there have been no prospective studies of the effectiveness of inhaled TA for the treatment of hemoptysis. OBJECTIVES:The goal of this study was to prospectively assess the effectiveness of TA inhalati...

journal_title：Chest

authors： Wand O,Guber E,Guber A,Epstein Shochet G,Israeli-Shani L,Shitrit D

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:There are several reports showing that expiratory muscle strength and endurance can be impaired in patients with COPD. This muscle weakness may have clinically relevant implications. Expiratory muscle training tended to improve cough and to reduce the sensation of respiratory effort during exercise in patien...

journal_title：Chest

authors： Weiner P,Magadle R,Beckerman M,Weiner M,Berar-Yanay N

更新日期：2003-08-01 00:00:00

abstract：:Surfactant replacement therapy (SRT) has a proven role in the treatment of neonatal respiratory distress syndrome and severe meconium aspiration syndrome in infants, and may have a role in the treatment of pediatric patients with ARDS. Although newer delivery mechanisms and strategies are being studied, the classic su...

journal_title：Chest

authors： Stevens TP,Sinkin RA

更新日期：2007-05-01 00:00:00