Abstract:
:We wanted to determine the efficacy of dobutamine infusions and Prbc transfusions on splanchnic tissue oxygen utilization by measuring gastric pHi. Physiologic parameters and pHi measurements via the use of a gastric tonometer were obtained in 21 septic patients before and after the administration of a dobutamine infusion (5 micrograms/kg/min) or the transfusion of two units of Prbc. Subsets of measurements with normal (greater than 7.32) and with low (less than 7.32) pHi were separately analyzed for each intervention. In the dobutamine low pHi group, pHi increased significantly from 7.16 +/- 0.03 to 7.24 +/- 0.03 (n = 9, p less than 0.05). In contrast, pHi failed to increase in the Prbc low pHi subgroup (7.16 +/- 0.05 to 7.17 +/- 0.04 [n = 10, p greater than 0.80]). We conclude that dobutamine rather than Prbc transfusions should be administered to reverse gastric intramucosal acidosis.
journal_name
Chestjournal_title
Chestauthors
Silverman HJ,Tuma Pdoi
10.1378/chest.102.1.184subject
Has Abstractpub_date
1992-07-01 00:00:00pages
184-8issue
1eissn
0012-3692issn
1931-3543pii
S0012-3692(16)35866-4journal_volume
102pub_type
杂志文章相关文献
CHEST文献大全abstract::In order to test the ability of magnetic resonance (MR) in the detection of pathologic flow conditions in man, we imaged 10 normal volunteers and 10 patients with congestive heart failure (CHF) with ECG-gated MR. We used a single spin-echo sequence on a transverse plane through the main vessels of the upper chest. The...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.92.4.645
更新日期:1987-10-01 00:00:00
abstract::Strapping of the chest causes decreased lung volumes and increased elastic recoil pressure. Such strapping was used in conjunction with single-breath nitrogen washout to study the effects of changes in these factors on the dynamics of the small airways. Studies consisted of simultaneous measurements of the quasistatic...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.76.1.83
更新日期:1979-07-01 00:00:00
abstract:STUDY OBJECTIVES:The aim of this study was to explore the relationship between quality of life and measures of asthma, such as lung function, reversibility to bronchodilation, exhaled nitric oxide (NO), and bronchial responsiveness to direct and indirect stimulus in patients with mild asthma in a primary care setting. ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.129.3.624
更新日期:2006-03-01 00:00:00
abstract::The levels of soluble IL-2R were measured in pleural fluid from patients with tuberculosis pleurisy. There were significantly elevated soluble IL-2R values in tuberculous pleural fluid as compared with pleural fluid of nontuberculous etiology including malignant, bacterial and transudative pleural effusions. In patien...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.97.5.1141
更新日期:1990-05-01 00:00:00
abstract:BACKGROUND:Signs of both motor and sensory nervous lesions have previously been shown in the upper airway of patients with OSA and habitual snorers. Snoring per se may damage all upper airway neurons over time, thereby causing progression to manifest sleep apnea. To test this hypothesis, nonsnoring subjects, untreated ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1016/j.chest.2020.01.032
更新日期:2020-05-01 00:00:00
abstract::Twenty-one patients with malignant pleural effusion (MPE) were prospectively entered into a nonrandomized, single-armed study to evaluate the efficacy and safety of recombinant interferon (IFN) alpha-2b (INTRON A; Schering-Plough; Kenilworth, NJ) as an intrapleural palliative agent. From March 1989 through February 19...
journal_title:Chest
pub_type: 临床试验,杂志文章
doi:10.1378/chest.111.6.1597
更新日期:1997-06-01 00:00:00
abstract:BACKGROUND:Acetazolamide and medroxyprogesterone acetate (MPA) are two respiratory stimulants that can be used in patients with stable hypercapnic COPD. DESIGN AND METHODS:The effects of acetazolamide, 250 mg bid, and MPA, 30 mg bid, on daytime and nighttime blood gas values and the influences on the hypercapnic and h...
journal_title:Chest
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1378/chest.123.5.1450
更新日期:2003-05-01 00:00:00
abstract:STUDY OBJECTIVES:Evidence exists that HIV-seropositive individuals may be at increased risk for the development of precocious pulmonary emphysema. HIV infection is also associated with antioxidant deficiency in both the serum and lungs, and it is therefore possible that increased oxidant stress may contribute to parenc...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.126.5.1439
更新日期:2004-11-01 00:00:00
abstract::Theophylline is commonly prescribed for patients with nonasthmatic chronic airflow obstruction (CAO) even though clinical efficacy is not well established. We studied objective and subjective responses to theophylline in 14 men with CAO. Subjects randomly received week-long treatments of placebo or theophylline at two...
journal_title:Chest
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1378/chest.82.5.538
更新日期:1982-11-01 00:00:00
abstract:STUDY OBJECTIVE:Childhood exposure to environmental tobacco smoke (ETS) adversely affects dynamic spirometric indexes as a result of combined early life (including in utero) and current exposure to parental smoking. The aim of our study was to investigate the effect of ETS on lung function and to identify the most sens...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.125.4.1387
更新日期:2004-04-01 00:00:00
abstract::We evaluated the effects of a new semisynthetic macrolide antibiotic, roxithromycin, on the bronchial hyperresponsiveness to histamine in children with asthma. Twelve hospitalized asthmatic children, aged 11 to 15 years (mean age, 12.9 years), were enrolled in this study. They were treated with 150 mg of roxithromycin...
journal_title:Chest
pub_type: 临床试验,杂志文章
doi:10.1378/chest.106.2.458
更新日期:1994-08-01 00:00:00
abstract:STUDY OBJECTIVES:The findings from conventional imaging modalities, such as chest CT, are frequently unreliable in patients with lung cancer. This study was designed to compare the relative diagnostic accuracies and utility of the two most widely used functional imaging examinations, F-18-2-fluoro-2-deoxyglucose (FDG) ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.125.2.494
更新日期:2004-02-01 00:00:00
abstract::Epidemiologic research has revealed a substantial portion of the general population with abnormal spirometry results that are characterized by decreased FEV1 and FVC but a preserved FEV1/FVC ratio. This restrictive spirometry pattern (RSP) is inconsistently defined in the literature and not well addressed by current g...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1378/chest.15-1045
更新日期:2016-01-01 00:00:00
abstract::Irradiation therapy for lung cancer is mostly restricted to conventional methods. To improve therapeutic ratio, we have combined a treatment planning and a gene therapy approach. Three-dimensional conformal radiotherapy is described as carried out by methods of gene therapy for radiation protection using the manganese...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1378/chest.113.1_supplement.46s
更新日期:1998-01-01 00:00:00
abstract:STUDY OBJECTIVES:The objective of this study is to examine the relationship between indoor environmental factors and childhood asthma in a subtropical area. DESIGN:A case-control study was performed using participants of a prevalence survey that included 165 schoolchildren with asthma and 165 age- and gender-matched c...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.114.2.393
更新日期:1998-08-01 00:00:00
abstract:OBJECTIVES:Tumor necrosis factor (TNF)-alpha is known to be a proinflammatory cytokine that has a pronounced negative inotropic effect and plays an important role in ischemic-reperfusion injury. METHODS:Twenty isolated rat hearts were randomly divided equally into two groups (heparin and non-heparin) and were perfused...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.128.3.1805
更新日期:2005-09-01 00:00:00
abstract::The diagnosis of aortic ring abscess by cross-sectional echocardiography has not been reported. In this paper, a case of bacterial endocarditis of the aortic valve extending to the aortic ring and the mitral valve is reported. The role of cross-sectional echocardiography in defining the anatomic distortion of the aort...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.74.5.576
更新日期:1978-11-01 00:00:00
abstract:UNLABELLED:Protected specimen brush (PSB) is considered to be one of the standard methods for the diagnosis of ventilator-associated pneumonia, but to our knowledge, intraindividual variability in results has not been reported previously. PURPOSE:To compare the results of two PSB performed in the same subsegment on pa...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.104.1.104
更新日期:1993-07-01 00:00:00
abstract::Bronchoscopy specimens from 183 known/suspected acquired immunodeficiency syndrome patients were evaluated for pathogens. In each case, transbronchial biopsies were evaluated and bronchoalveolar lavage material was cultured for viruses, fungi and mycobacteria and examined cytologically. A specimen was considered posit...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.98.1.24
更新日期:1990-07-01 00:00:00
abstract:BACKGROUND:Current guidelines recommend the use of inhaled corticosteroids (ICSs) added to long-acting beta(2)-agonists (LABAs) for treatment of symptomatic patients with severe and very severe COPD. However, the evidence has been inconclusive. The aim of this review was to assess the safety and efficacy of LABAs/ICSs ...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1378/chest.09-0821
更新日期:2009-10-01 00:00:00
abstract::A case of disseminated histoplasmosis followed later by disseminated coccidioidomycosis is described. The clinical illness and immunologic studies suggest subtle defects that may have existed antecedent to infection and, thus, provided an opportunity for widespread dissemination by these normally nonopportunistic orga...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.72.2.238
更新日期:1977-08-01 00:00:00
abstract:BACKGROUND:Severe pneumonia requiring ICU admission has not been well characterized with respect to long-term outcomes or predictors thereof. We examined the association between premorbid functional status and mortality in patients with severe pneumonia. METHODS:From 2000 to 2002, a population-based cohort of adults w...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.10-1054
更新日期:2011-01-01 00:00:00
abstract:OBJECTIVES:To report observations on preserved regular atrial electrical and mechanical systole during ventricular fibrillation (VF) and to quantitate blood flow generated by atrial contractions in this setting. METHODS:In 10 rats, right atrial pressure pulses were continuously recorded before and for an interval of 8...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.117.4.1118
更新日期:2000-04-01 00:00:00
abstract:BACKGROUND:In adult patients, the consistent use of language to describe dyspnea enhances patient-provider communication and contributes to diagnostic and therapeutic decisions. The objective of this research was to determine whether pediatric patients similarly display consistency in the language used to describe "unc...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.10-2388
更新日期:2011-04-01 00:00:00
abstract:BACKGROUND:Inhaled magnesium (Mg) seemed to have a mild protective (nonbronchodilator) effect against histamine and methacholine. Inhaled sodium metabisulfite (MBS) causes bronchoconstriction in asthma through indirect mechanisms that involve sensory nerve stimulation, and it is extensively used to study airway hyperre...
journal_title:Chest
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1378/chest.111.4.858
更新日期:1997-04-01 00:00:00
abstract::A patient with Ewing's sarcoma of the left scapula received prophylactic radiotherapy to the left lung following wide excision of the tumor. While the left lung remained free of tumor, there was metastatic invasion of the right lung within ten months of the initial diagnosis of the disease. Since Ewing's sarcoma frequ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.70.3.393
更新日期:1976-09-01 00:00:00
abstract::The usefulness of lung-thorax compliance (or elastance) as an index of pulmonary compliance (or elastance) was examined in 15 patients being ventilated for acute respiratory failure. Mean lung-thorax elastance (ELT) was 27.9 +/- 2.6 cm H2O/L, and the chest wall accounted for 34 +/- 2 percent of the mean total value. C...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.80.3.304
更新日期:1981-09-01 00:00:00
abstract:BACKGROUND:Previous studies have shown "beat-to-beat" variation in systemic BP with high-frequency jet ventilation (HFJV). However, it is not clear if such changes are paralleled by changes in cardiac output. OBJECTIVE:To characterize the effect of HFJV near or equal to the heart rate (HR) on beat-to-beat cardiac outp...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1378/chest.112.6.1600
更新日期:1997-12-01 00:00:00
abstract:STUDY OBJECTIVE:To evaluate the safety and efficacy of additional minocycline pleurodesis after thoracoscopic treatment of primary spontaneous pneumothorax. DESIGN:Retrospective comparative study with a historical control. SETTING:Thoracic surgical division of a university-affiliated tertiary medical center. PATIENT...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.125.1.50
更新日期:2004-01-01 00:00:00
abstract:STUDY OBJECTIVE:To ascertain the incidence, types, morbidity, and mortality of infectious episodes in isolated lung transplant recipients. DESIGN:Retrospective chart review of patients who have undergone transplants over a six-year period in one institution. PATIENTS:Twenty-three single and 17 double lung transplants...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.101.4.1056
更新日期:1992-04-01 00:00:00