Abstract:
STUDY OBJECTIVES:To evaluate the differences in the clinical, radiologic, and laboratory features of pulmonary tuberculosis (TB) in older patients, as compared to younger patients. DESIGN:A meta-analysis (the Schmidt-Hunter method) of published works found in MEDLINE and other sources was performed. A total of 12 studies were collected, and each variable was submitted to meta-analysis. RESULTS:No differences were found between older (>/= 60 years old) and younger TB patients with respect to male predominance, evolution time before diagnosis, prevalence of cough, sputum production, weight loss, fatigue/malaise, radiographic upper lobes lesions, positive acid-fast bacilli in sputum, anemia or hemoglobin level, and serum aminotransferases. A lower prevalence of fever, sweating, hemoptysis, cavitary disease, and positive purified protein derivative, as well as lower levels of serum albumin and blood leukocytes were noticed among older patients. In addition, the older population had a greater prevalence of dyspnea and some concomitant conditions, such as cardiovascular disorders, COPD, diabetes, gastrectomy history, and malignancies. CONCLUSIONS:This meta-analytical review identified the main differences of older TB patients, as compared to younger TB patients, that should be considered during the diagnostic evaluation. Most of these differences are explained by the already known physiologic changes that occur during aging.
journal_name
Chestjournal_title
Chestauthors
Pérez-Guzmán C,Vargas MH,Torres-Cruz A,Villarreal-Velarde Hdoi
10.1378/chest.116.4.961subject
Has Abstractpub_date
1999-10-01 00:00:00pages
961-7issue
4eissn
0012-3692issn
1931-3543pii
S0012-3692(15)37146-4journal_volume
116pub_type
杂志文章,meta分析相关文献
CHEST文献大全abstract::Preclinical studies indicate that allogeneic human mesenchymal stem cells (MSC) may be useful for the treatment of several clinical disorders, including sepsis, acute renal failure, acute myocardial infarction, and more recently, acute lung injury (ALI). This article provides a brief review of the biologic qualities o...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1378/chest.10-0518
更新日期:2010-10-01 00:00:00
abstract::Adults with CF followed in a university center were assessed for the presence of the most common CF gene mutation, delta-F508. Excluding one member of a sibling pair, 29 of 55 subjects had two copies of delta-F508 (homozygotes), 23 had one copy of delta-F508 with the other CF mutation not identified (complex heterozyg...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.102.2.506
更新日期:1992-08-01 00:00:00
abstract::Three patients had hypertrophic obstructive cardiomyopathy and coronary artery spasm. The clinical diagnosis of hypertrophic obstructive cardiomyopathy, in all patients, was confirmed by echocardiography and angiography. Significant spasm of the right coronary artery was demonstrated in each patient by selective coron...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.76.6.636
更新日期:1979-12-01 00:00:00
abstract::Lung scans with technetium sulfur colloid were performed in ten patients with life-threatening hemoptysis and nondiagnostic chest roentgenograms. Localized deposition of radionuclide was demonstrated in five of the six patients who were studied during active bleeding. These abnormalities were confirmed bronchoscopical...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.86.2.208
更新日期:1984-08-01 00:00:00
abstract:BACKGROUND:Architectural design of health-care facilities can influence patient safety; however, it is unknown whether patient outcomes are significantly affected by ICU design. METHODS:Six hundred sixty-four patients admitted to the medical ICU (MICU) of Columbia University Medical Center during 2008 were included in...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.09-1458
更新日期:2010-05-01 00:00:00
abstract:BACKGROUND:Excessive sleepiness (ES) is a common symptom of OSA, which often persists despite primary OSA therapy. This phase III randomized withdrawal trial evaluated solriamfetol (JZP-110) for the treatment of ES in adults with OSA. METHODS:After 2 weeks of clinical titration (n = 174) and 2 weeks of stable dose adm...
journal_title:Chest
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.chest.2018.11.005
更新日期:2019-02-01 00:00:00
abstract:STUDY OBJECTIVE:To determine the extent to which rapid on-site cytologic evaluation (ROSE) of transbronchial needle aspiration (TBNA) samples can safely and cost-effectively reduce the need for additional biopsy during bronchoscopy. SETTING:University Hospital in Long Island, NY. PATIENT AND METHODS:Forty-four bronch...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.128.2.869
更新日期:2005-08-01 00:00:00
abstract::From 1982 to 1989, ECD was performed on 18 patients suffering from poorly-tolerated massive pulmonary embolism, for whom classic treatments (fibrinolytics and surgery) were impossible. Eleven of these 18 patients immediately improved (S group). This procedure was unsuccessful in other seven patients (F group). Thirtee...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.100.3.655
更新日期:1991-09-01 00:00:00
abstract::A 53-year-old man with tracheobronchomalacia had two stents placed in his airways to maintain patency. He ingested one of the tracheal stents that was inadvertently dislodged during a brief coughing episode. The swallowed stent was recovered without complications. ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.108.3.875
更新日期:1995-09-01 00:00:00
abstract:BACKGROUND:COPD includes the chronic bronchitis (CB) and emphysema phenotypes. Although it is generally assumed that emphysema or chronic airflow obstruction (CAO) is associated with worse quality of life (QOL) than is CB, this assumption has not been tested. METHODS:The current study's analyses from the Lovelace Smok...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.14-2240
更新日期:2015-08-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to identify the CT scan features that predict patient outcome after reexpansion procedures in patients with the fibrotic stage of endobronchial TB. METHODS:We retrospectively enrolled 30 patients (four men, 26 women) aged 32 +/- 11 years who had lobar or whole-lung atelectasis ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.09-1846
更新日期:2010-08-01 00:00:00
abstract::Among 1,700 primary tumors of the lung, there were 53 cases of bronchial adenoma (3.1 percent); 38 (72 percent) of the 53 were typical carcinoids, and the remaining 15 were of a higher grade of malignant neoplasm. There was a slight predominance of female patients, and the age of greatest incidence was between 30 and ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.77.1.81
更新日期:1980-01-01 00:00:00
abstract::Based on the theory that obstructive (OSA) and central (CSA) sleep apneas share common pathophysiologic mechanisms, we attempted to treat eight patients with predominantly CSA by continuous positive airway pressure (CPAP). All patients exhibited repetitive episodes of CSA and mixed sleep apneas (MSA) in the supine pos...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.90.2.165
更新日期:1986-08-01 00:00:00
abstract::Care of ventilator-dependent patients requires considerable resources, yet the long-term outcomes of this type of care have rarely been described. We retrospectively investigated the posthospital course of elderly patients who survived an episode of prolonged ventilator dependency to describe survival rates, subsequen...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.96.5.1120
更新日期:1989-11-01 00:00:00
abstract::Although the principal actions of clonidine are linked to its centrally mediated suppression of sympathetic activity, its inhibition of the renin axis also may contribute to its antihypertensive effects. In patients with essential hypertension studied in a clinical research center, clonidine-induced decreases in diast...
journal_title:Chest
pub_type: 杂志文章
doi:
更新日期:1983-02-01 00:00:00
abstract:BACKGROUND:Human telomere disease consists of a wide spectrum of disorders, including pulmonary, hepatic, and bone marrow abnormalities. The extent of bone marrow and liver abnormalities in patients with interstitial lung disease (ILD) and short telomeres is unknown. METHODS:The lung transplant clinic established a pr...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.14-0631
更新日期:2015-06-01 00:00:00
abstract::Clinically apparent myocardial disease is infrequent in sarcoidosis. However, autopsy data show myocardial involvement in up to 30 percent of patients. Unexplained exertional symptomatology is a common complaint in patients with sarcoidosis. In this study, we investigated whether abnormal cardiac function might limit ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.100.1.44
更新日期:1991-07-01 00:00:00
abstract::The clinical and histopathologic features of pulmonary amyloidosis were reviewed in 22 patients with systemic amyloidosis who came to autopsy. Eleven of 12 patients (92 percent) with primary amyloidosis had prominent interalveolar amyloid deposits. Symptoms attributable to these deposits were found in four cases (33 p...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.74.5.543
更新日期:1978-11-01 00:00:00
abstract::There is a general consensus that antimicrobial resistance in the hospital setting has emerged as an important variable influencing patient outcome and resource utilization. Hospitals worldwide are faced with increasingly rapid emergence and spread of antibiotic-resistant bacteria. Both antibiotic-resistant Gram-negat...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1378/chest.123.5_suppl.464s
更新日期:2003-05-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Continuous administration of aerosolized beta 2-agonists has been suggested as an effective treatment for severe reversible airways disease. To facilitate continuous therapy and avoid a feed system for small-volume nebulizers (SVNs), a large-volume medication nebulizer (Vortran HEART) was deve...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.111.5.1200
更新日期:1997-05-01 00:00:00
abstract:OBJECTIVES:We aimed to identify the bronchial response to inhaled methacholine in patients with mitral stenosis (MS) and to clarify whether or not the bronchial hyperreactivity (BHR) is reversible after percutaneous mitral balloon valvulotomy (PBMV). PATIENTS AND SETTING:Thirty patients with MS and 28 age-matched heal...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.116.6.1582
更新日期:1999-12-01 00:00:00
abstract:BACKGROUND:The prevalence of obesity is increasing, and there is evidence that obesity, in particular abdominal obesity as a marker of insulin resistance, is negatively associated with pulmonary function. The mechanism for this association and the best marker of abdominal adiposity in relation to pulmonary function is ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.129.4.853
更新日期:2006-04-01 00:00:00
abstract:OBJECTIVE:Fractional flow reserve (FFR) is a valid surrogate for hemodynamic significance in stenotic native coronary arteries, but its validity in patients with coronary stent restenosis is unknown. DESIGN:Prospective. SETTING:University hospital. PATIENTS:We studied 42 patients (mean age +/- 1 SD, 62 +/- 10 years)...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.128.3.1645
更新日期:2005-09-01 00:00:00
abstract::One hundred one subjects living in northwest Hunan Province, People's Republic of China (PRC) were tested with histolyn, (Berkeley Biological Laboratories), spherulin (Berkeley Biological Laboratories), and tubersol (PPD 5 tuberculin units, Connaught Laboratories). Age of the tested subjects ranged from 16 to 58 years...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.97.6.1356
更新日期:1990-06-01 00:00:00
abstract::The levels of soluble IL-2R were measured in pleural fluid from patients with tuberculosis pleurisy. There were significantly elevated soluble IL-2R values in tuberculous pleural fluid as compared with pleural fluid of nontuberculous etiology including malignant, bacterial and transudative pleural effusions. In patien...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.97.5.1141
更新日期:1990-05-01 00:00:00
abstract::The effects of the administration of ouabain on the peak negative left ventriculat (LV) dP/dt were studied in 14 patients with acute myocardial infarction. Prior to administration of ouabain, negative LV dP/at was lower than previously reported for patients without coronary arterial disease. One hour after administrat...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.70.2.259
更新日期:1976-08-01 00:00:00
abstract::We present an unusual case of a patient with chronic hepatitis C who experienced dyspnea, fever, and cough after 2 1/2 months' treatment with interferon. His radiograph demonstrated diffuse pulmonary infiltrates and bronchoalveolar lavage fluid showed an increase in lymphocytes, especially CD8-positive cells. The lung...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.106.2.612
更新日期:1994-08-01 00:00:00
abstract::99mTechnetium macroaggregated albumin has successfully been used to define severe postoperative pulmonary vasoconstriction in a four-month-old boy with D-transposition of the great vessels who had undergone a Blalock-Hanlon surgical atrial septectomy. Radionuclide imaging documented clinically suspected pulmonary vaso...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.76.3.274
更新日期:1979-09-01 00:00:00
abstract:BACKGROUND:Patients with chronic bird fancier's lung (BFL) can be classified into two types. One group of patients develops chronic disease with fluctuating acute episodes, including low-grade fever, mild exertional dyspnea, and cough (fluctuating chronic BFL; formerly termed recurrent and relapsing chronic BFL). The o...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.118.5.1382
更新日期:2000-11-01 00:00:00
abstract::A case of double-orifice mitral valve in a 16-year-old Japanese boy is presented. Two-dimensional echocardiography, including transesophageal approach, showed two approximately equal orifices with three papillary muscles. Color Doppler echocardiography showed a mild mitral regurgitation from both orifices. No other ca...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1378/chest.104.5.1616
更新日期:1993-11-01 00:00:00