Abstract:
:The levels of soluble IL-2R were measured in pleural fluid from patients with tuberculosis pleurisy. There were significantly elevated soluble IL-2R values in tuberculous pleural fluid as compared with pleural fluid of nontuberculous etiology including malignant, bacterial and transudative pleural effusions. In patients with tuberculous pleurisy, the level of soluble IL-2R in pleural fluid was markedly greater than that in serum. Furthermore, a significant positive correlation was observed between soluble IL-2R levels and adenosine deaminase levels in tuberculous pleural fluid. These findings suggest that elevated levels of pleural fluid soluble IL-2R in tuberculous pleurisy could reflect the local proliferation of activated T-cells and may be clinically useful in the diagnostic procedures for patients with pleural tuberculosis.
journal_name
Chestjournal_title
Chestauthors
Ito M,Kojiro N,Shirasaka T,Moriwaki Y,Tachibana I,Kokubu Tdoi
10.1378/chest.97.5.1141subject
Has Abstractpub_date
1990-05-01 00:00:00pages
1141-3issue
5eissn
0012-3692issn
1931-3543pii
S0012-3692(15)41013-Xjournal_volume
97pub_type
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