Elevated levels of soluble interleukin-2 receptors in tuberculous pleural effusions.

Abstract:

:The levels of soluble IL-2R were measured in pleural fluid from patients with tuberculosis pleurisy. There were significantly elevated soluble IL-2R values in tuberculous pleural fluid as compared with pleural fluid of nontuberculous etiology including malignant, bacterial and transudative pleural effusions. In patients with tuberculous pleurisy, the level of soluble IL-2R in pleural fluid was markedly greater than that in serum. Furthermore, a significant positive correlation was observed between soluble IL-2R levels and adenosine deaminase levels in tuberculous pleural fluid. These findings suggest that elevated levels of pleural fluid soluble IL-2R in tuberculous pleurisy could reflect the local proliferation of activated T-cells and may be clinically useful in the diagnostic procedures for patients with pleural tuberculosis.

journal_name

Chest

journal_title

Chest

authors

Ito M,Kojiro N,Shirasaka T,Moriwaki Y,Tachibana I,Kokubu T

doi

10.1378/chest.97.5.1141

subject

Has Abstract

pub_date

1990-05-01 00:00:00

pages

1141-3

issue

5

eissn

0012-3692

issn

1931-3543

pii

S0012-3692(15)41013-X

journal_volume

97

pub_type

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