Long-term outcomes for elderly survivors of prolonged ventilator assistance.

Abstract:

:Care of ventilator-dependent patients requires considerable resources, yet the long-term outcomes of this type of care have rarely been described. We retrospectively investigated the posthospital course of elderly patients who survived an episode of prolonged ventilator dependency to describe survival rates, subsequent use of health care resources, and functional abilities. Our data suggest that the use of prolonged mechanical ventilation in the elderly produces few survivors at considerable expense. Poor overall outcomes occurred despite considerable consumption of medical and nursing resources by the survivors.

journal_name

Chest

journal_title

Chest

authors

Elpern EH,Larson R,Douglass P,Rosen RL,Bone RC

doi

10.1378/chest.96.5.1120

subject

Has Abstract

pub_date

1989-11-01 00:00:00

pages

1120-4

issue

5

eissn

0012-3692

issn

1931-3543

pii

S0012-3692(16)35140-6

journal_volume

96

pub_type

杂志文章

相关文献

CHEST文献大全
  • Safety of nitrate withdrawal in angina-free and hemodynamically stable patients with coronary artery disease.

    abstract:STUDY OBJECTIVES:To assess the consequences of nitrate withdrawal in angina-free and hemodynamically stable coronary patients. DESIGN:Prospective, open, intervention study. SETTING:Cardiology outpatient clinic of a university-affiliated municipal hospital. PATIENTS:Angina-free patients who were hemodynamically stabl...

    journal_title:Chest

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0012-3692(15)33392-4

    authors: George J,Kitzis I,Zandorf D,Golovner M,Shapira I,Laniado S,Roth A

    更新日期:2003-11-01 00:00:00

  • Clinical significance of nontuberculous mycobacteria isolated from respiratory specimens in Korea.

    abstract:STUDY OBJECTIVES:Precise epidemiologic data regarding nontuberculous mycobacterial (NTM) lung infection in many Asian countries have been relatively unavailable. In order to determine the clinical significance of NTM isolated from respiratory specimens, we reviewed medical records from all patients from whom NTM isolat...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.129.2.341

    authors: Koh WJ,Kwon OJ,Jeon K,Kim TS,Lee KS,Park YK,Bai GH

    更新日期:2006-02-01 00:00:00

  • The effects of flosequinan on hemodynamics and oxygen delivery in cor pulmonale.

    abstract::The hemodynamic effects of a new orally active vasodilator, flosequinan, were compared with placebo (single blind) over 24 h in eight patients with pulmonary hypertension secondary to severe chronic obstructive pulmonary disease. Mean pulmonary artery pressure was reduced by 5.1 (3.4, 6.7) mm Hg (mean 95 percent CI) (...

    journal_title:Chest

    pub_type: 临床试验,杂志文章

    doi:10.1378/chest.102.4.1155

    authors: Elborn JS,Richardson G,Murphy P,MacMahon J

    更新日期:1992-10-01 00:00:00

  • Standard therapy for tuberculosis 1985.

    abstract::Numerous clinical trials of chemotherapy for tuberculosis conducted throughout the world over the past 4 decades have established 2 basic principles of treatment: effective treatment requires the initial concomitant administration of at least 2 drugs to which the patient's organisms are susceptible; and cure of tuber...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.87.2.117s

    authors: Snider DE Jr,Cohn DL,Davidson PT,Hershfield ES,Smith MH,Sutton FD Jr

    更新日期:1985-02-01 00:00:00

  • Distribution of bronchial nonspecific reactivity in the general population.

    abstract::We investigated 654 subjects of a small Lombardy (Italy) town between 15 and 64 years of age who were representative of the general population. By clinical examination, the sample included 535 normal subjects (164 normal smokers, 341 normal nonsmokers, 30 normal subjects with acute upper respiratory illness within 30 ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.93.1.26

    authors: Cerveri I,Bruschi C,Zoia MC,Zanon P,Maccarini L,Grassi M,Rampulla C

    更新日期:1988-01-01 00:00:00

  • The recrudescent epidemic of retrolental fibroplasia.

    abstract::We are probably observing a recrudescent epidemic of RLF which has elicited surprisingly little attention from the medical community. Given present data, it is not unreasonable to conclude that there is a true epidemic and that its etiologic basis involves a population of infants with high susceptibility to oxygen tox...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.89.4.576

    authors: Robin ED,Burke CM

    更新日期:1986-04-01 00:00:00

  • Long-term intermittent exposure to high ambient CO2 causes respiratory disturbances during sleep in submariners.

    abstract:BACKGROUND:During most of the cruise, submarines are detached from their environment. Therefore, O(2) levels are relatively low (19 kPa, 144 mm Hg) and CO(2) levels are high (1 kPa, 7.6 mm Hg). There are, however, periods during ventilation of the submarine in which CO(2) levels drop and O(2) levels increase. The objec...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.124.5.1716

    authors: Margel D,White DP,Pillar G

    更新日期:2003-11-01 00:00:00

  • Postinfluenza toxic shock syndrome.

    abstract::Postinfluenza toxic shock syndrome is a recently described entity that results from a respiratory tract infection with toxin-producing Staphylococcus aureus following an episode of influenza or influenzalike illness. This report describes a 19-year-old man who developed an influenza B respiratory infection complicated...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.95.5.1153

    authors: Prechter GC,Gerhard AK

    更新日期:1989-05-01 00:00:00

  • Bronchoalveolar lavage findings in patients seropositive for the human immunodeficiency virus (HIV).

    abstract::To evaluate bronchoalveolar lavage (BAL) findings in patients infected with human immunodeficiency virus (HIV), 39 patients seropositive for the virus but with no history of opportunistic infection were studied. Opportunistic organisms such as Pneumocystis carinii were not found in any of the 35 BAL fluids sent for sp...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.97.5.1066

    authors: Johnson JE,Anders GT,Hawkes CE,LaHatte LJ,Blanton HM

    更新日期:1990-05-01 00:00:00

  • Multidisciplinary Team-Based Management of Incidentally Detected Lung Nodules.

    abstract:BACKGROUND:Each year, > 1.5 million Americans are diagnosed with an incidentally detected lung nodule. Practice guidelines attempt to balance the benefit of early detection of lung cancer with the risks of diagnostic testing, but adherence to guidelines is low. The goal of this study was to determine guideline adherenc...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1016/j.chest.2019.11.032

    authors: Verdial FC,Madtes DK,Cheng GS,Pipavath S,Kim R,Hubbard JJ,Zadworny M,Wood DE,Farjah F

    更新日期:2020-04-01 00:00:00

  • Chemical pneumonitis due to exposure to bromine compounds.

    abstract::A 60-year-old laboratory technician developed pulmonary infiltrates consistent with chemical pneumonitis following accidental exposure to a mixture of hydrogen bromide and phosphorus tribromide. A protracted clinical course ensued consistent with bronchiolitis obliterans. These problems may have been avoided if the po...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.94.1.208

    authors: Kraut A,Lilis R

    更新日期:1988-07-01 00:00:00

  • Transbronchial lung biopsy via the fiberoptic bronchoscope. Experience with 107 consecutive cases and comparison with bronchial brushing.

    abstract::Transbronchial lung biopsy (TBB) was performed during fiberoptic bronchoscopy under fluoroscopic guidance in 107 patients. TBB was diagnostic in 17 of 21 (81 percent) cases with localized malignant lesions greater than 4 cm in diameter and bronchial brushing was positive in 12 (57 percent). TBB was diagnostic in 14 of...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.68.4.524

    authors: Ellis JH Jr

    更新日期:1975-10-01 00:00:00

  • Is a raised bicarbonate, without hypercapnia, part of the physiologic spectrum of obesity-related hypoventilation?

    abstract:BACKGROUND:Obesity hypoventilation syndrome (OHS) conventionally includes awake hypercapnia, but an isolated raised bicarbonate, even in the absence of awake hypercapnia, may represent evidence of "early" OHS. We investigated whether such individuals exhibit certain features characteristic of established OHS. METHODS:...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.14-1279

    authors: Manuel ARG,Hart N,Stradling JR

    更新日期:2015-02-01 00:00:00

  • Terbutaline in the treatment of acute asthma in childhood.

    abstract::Forty-eight children with known asthma (ranging in age from 2 to 16 years) were studied during an acute attack. Each received either terbutaline or epinephrine subcutaneously in a random double-blind fashion. Measurement of heart rate, respiratory rate, and systemic arterial systolic and diastolic blood pressures and ...

    journal_title:Chest

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1378/chest.72.5.614

    authors: Davis WJ,Pang LM,Chernack WJ,Mellins RB

    更新日期:1977-11-01 00:00:00

  • GISSI update. Which patients with myocardial infarction should receive thrombolysis?

    abstract::Large-scale, randomized clinical trials have produced over the last few years a wide consensus about the role of thrombolysis in the treatment of acute myocardial infarction (AMI). It has been estimated from the trials with broader inclusion criteria that about 40% of the patients admitted to coronary care units with ...

    journal_title:Chest

    pub_type: 杂志文章,meta分析

    doi:10.1378/chest.101.4.116s

    authors: Franzosi MG,Maggioni AP,Tognoni G

    更新日期:1992-04-01 00:00:00

  • Linezolid vs vancomycin: analysis of two double-blind studies of patients with methicillin-resistant Staphylococcus aureus nosocomial pneumonia.

    abstract:OBJECTIVE:To assess the effect of baseline variables, including treatment, on outcome in patients with nosocomial pneumonia due to methicillin-resistant Staphylococcus aureus (MRSA). DESIGN:Retrospective analysis of data from two prospective, randomized, double-blind studies. SETTING:Multinational study with 134 site...

    journal_title:Chest

    pub_type: 杂志文章

    doi:

    authors: Wunderink RG,Rello J,Cammarata SK,Croos-Dabrera RV,Kollef MH

    更新日期:2003-11-01 00:00:00

  • Kyphoscoliosis and respiratory failure. A patient treated with assisted ventilation for 27 years.

    abstract::A 62-year-old woman had had kyphoscoliosis since age 12 years. Respiratory failure developed at age 35 years following a respiratory infection. A tracheostomy was done and she required assisted ventilation using a respiratory (Bird). Many attempts at weaning her from the ventilator were unsuccessful. She has remained ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.98.5.1297

    authors: Woolf CR

    更新日期:1990-11-01 00:00:00

  • Efficacy of tracheal and bronchial stent placement on respiratory functional tests.

    abstract::Stent placement is the only available treatment in patients presenting either a localized external compression or a malacia of the tracheobronchial tree. To assess the functional benefit of prosthesis insertion in these indications, we compared functional respiratory values before, immediately after (48 h), and at som...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.107.3.741

    authors: Vergnon JM,Costes F,Bayon MC,Emonot A

    更新日期:1995-03-01 00:00:00

  • Deficiency of alveolar fluid glutathione in patients with sepsis and the adult respiratory distress syndrome.

    abstract::The adult respiratory distress syndrome (ARDS) is a devastating clinical illness characterized by refractory hypoxemia and high-permeability pulmonary edema. Reactive oxygen species such as hydrogen peroxide and hypochlorous acid may play a key role in the pathogenesis of the acute lung injury. Glutathione (GSH) is a ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.100.5.1397

    authors: Pacht ER,Timerman AP,Lykens MG,Merola AJ

    更新日期:1991-11-01 00:00:00

  • Risk factors for extubation failure in patients following a successful spontaneous breathing trial.

    abstract:BACKGROUND:To assess the factors associated with reintubation in patients who had successfully passed a spontaneous breathing trial. METHODS:We used logistic regression and recursive partitioning analyses of prospectively collected clinical data from adults admitted to ICUs of 37 hospitals in eight countries, who had ...

    journal_title:Chest

    pub_type: 杂志文章,多中心研究

    doi:10.1378/chest.130.6.1664

    authors: Frutos-Vivar F,Ferguson ND,Esteban A,Epstein SK,Arabi Y,Apezteguía C,González M,Hill NS,Nava S,D'Empaire G,Anzueto A

    更新日期:2006-12-01 00:00:00

  • Genetics of asthma and COPD. Similar results for different phenotypes.

    abstract::Asthma and COPD are common respiratory diseases that are caused by the interaction of genetic susceptibility with environmental factors. Environmental influences are important in both diseases, and although there are differences in genetic susceptibilities, there are also similarities. Three examples of interest for b...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.126.2_suppl_1.105S

    authors: Meyers DA,Larj MJ,Lange L

    更新日期:2004-08-01 00:00:00

  • Refractory hypoxemia in a 23-year-old patient with Budd-Chiari syndrome.

    abstract::Antiphospholipid syndrome is an autoimmune disorder characterized by a hypercoagulable state, leading to arterial and venous thrombosis. We present a 23-year-old patient, suspected of having Budd-Chiari syndrome due to antiphospholipid syndrome, who developed severe and progressive hypoxemia, requiring prolonged mecha...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.13-2879

    authors: Bunge JJH,Wiersema US,Moelker A,van Bommel J,Tjwa ETTL

    更新日期:2014-11-01 00:00:00

  • Greenfield inferior vena cava filter dislodged during central venous catheter placement.

    abstract::Two cases of a Greenfield inferior vena cava (IVC) filter being dislodged during central venous catheter placement are described. This event appears to be related to J-tip guidewire use during venous catheterization. To our knowledge, this occurrence previously has not been reported. One of the two filters was dislodg...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.106.3.957

    authors: Marelich GP,Tharratt RS

    更新日期:1994-09-01 00:00:00

  • Quadricuspid semilunar valves.

    abstract::Forty-seven cases of quadricuspid semilunar valves which were autopsied were reviewed. The ratio of quadricuspid pulmonic valve to quadricuspid aortic valve was 5:1. Among the 35 patients with quadricuspid pulmonic valves, there were ten patients with clinical and pathologic evidence of coexisting congenital cardiac d...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.72.2.186

    authors: Davia JE,Fenoglio JJ,DeCastro CM,McAllister HA Jr,Cheitlin MD

    更新日期:1977-08-01 00:00:00

  • Immediate operative treatment for massive hemoptysis.

    abstract::A series of 15 patients with life threatening, massive hemoptysis is reported. Thirteen of these patients underwent immediate operative treatment with only three deaths. One died after bronchoscopic identification of the bleeding site while awaiting elective thoracotomy. The other patient left the hospital against med...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.67.2.152

    authors: McCollun WB,Mattox KL,Guinn GA,Beall AC Jr

    更新日期:1975-02-01 00:00:00

  • Bilateral tuberculous pleural effusions with markedly different characteristics.

    abstract::A 72-year-old man presented with malaise, weight loss, and cough. Chest radiograph revealed bilateral pleural effusions. On thoracentesis, the left effusion was a clear yellow exudate with more than 90% lymphocytes, and the right effusion was a grossly bloody exudate with more than 90% neutrophils. Cultures of both ef...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.110.3.849

    authors: Murin S,Moritz E

    更新日期:1996-09-01 00:00:00

  • Cigarette smoking and incidence of chronic bronchitis and asthma in women.

    abstract:STUDY OBJECTIVE:To examine the relation of smoking habits and development of asthma in a large cohort of US women. DESIGN:Prospective cohort study. PARTICIPANTS:Among 74,072 women, 34 to 68 years of age, who were free of major diseases, we documented 671 incident asthma cases and 798 incident cases of chronic bronchi...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.108.6.1557

    authors: Troisi RJ,Speizer FE,Rosner B,Trichopoulos D,Willett WC

    更新日期:1995-12-01 00:00:00

  • Effects of bacterial infection on airway antimicrobial peptides and proteins in COPD.

    abstract:BACKGROUND:Pathogenic bacteria colonize the airways of 30% to 40% of patients with COPD and cause approximately 50% of exacerbations. New strains of nontypeable Haemophilus influenzae (NTHI) and Moraxella catarrhalis are associated with exacerbations. Antimicrobial protein/peptides (AMPs) play important roles in innate...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.10-2760

    authors: Parameswaran GI,Sethi S,Murphy TF

    更新日期:2011-09-01 00:00:00

  • Encroachment upon the lungs of large chronic pericardial effusion. Pulmonary tamponade?

    abstract::Pulmonary encroachment by a large chronic pericardial effusion is reported in a woman with pericardiocentesis whom we recently treated. A restrictive pulmonary impairment is documented with pulmonary function data obtained before and after drainage of the effusion and the patient's dyspnea improved. ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.93.2.434

    authors: Kane GC,Figueroa WG

    更新日期:1988-02-01 00:00:00

  • Plug closure of patent ductus arteriosus by transfemoral catheter method. A comparative study with surgery and a new technical modification.

    abstract::Plug closure of patent ductus arteriosus without thoracotomy is reliable and can be a good alternative to surgical closure for selected patients. We report our experiences with plug closure in 87 consecutive patients (age range, 3 to 38 years). Closure was successful in 83 patients (95 percent). There has been no mort...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.70.5.631

    authors: Kitamura S,Sato K,Naito Y,Shimizu Y,Fujino M

    更新日期:1976-11-01 00:00:00