Selective digestive decontamination should not be routinely employed.

Abstract:

:There is a general consensus that antimicrobial resistance in the hospital setting has emerged as an important variable influencing patient outcome and resource utilization. Hospitals worldwide are faced with increasingly rapid emergence and spread of antibiotic-resistant bacteria. Both antibiotic-resistant Gram-negative bacilli and Gram-positive bacteria are reported as important causes of hospital-acquired infections. Few antimicrobial agents are available for effective treatment. Selective digestive decontamination (SDD) is a technique aimed at selectively eliminating aerobic Gram-negative bacilli and yeast from the mouth and stomach to reduce the occurrence of hospital-acquired infections, including ventilator-associated pneumonia. Unfortunately, the application of SDD has been associated with emergence of antibiotic-resistant bacterial strains, limiting its overall utility.

journal_name

Chest

journal_title

Chest

authors

Kollef MH

doi

10.1378/chest.123.5_suppl.464s

subject

Has Abstract

pub_date

2003-05-01 00:00:00

pages

464S-8S

issue

5 Suppl

eissn

0012-3692

issn

1931-3543

pii

S0012-3692(15)33077-4

journal_volume

123

pub_type

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