Abstract:
:The effects of the administration of ouabain on the peak negative left ventriculat (LV) dP/dt were studied in 14 patients with acute myocardial infarction. Prior to administration of ouabain, negative LV dP/at was lower than previously reported for patients without coronary arterial disease. One hour after administration of ouabain, significant (P less than 0.05) increases in peak positive LV dP/dt and maximal velocity of contractile-element shortening and decreases in LV diastolic pressure were present. These changes were associated with small and insignificant increases in negative LV dP/dt. Early LV relaxation rate is impaired in patients with acute myocardial infarction; however, the reduction in LV diastolic pressures which occurs after administration of ouabain does not appear to be due to an increase in the rate of early LV relaxation but rather is probably related to improved contractility.
journal_name
Chestjournal_title
Chestauthors
Loeb HS,Sinno MZ,Rahimtoola SH,Gunnar RM,Blount SG Jrdoi
10.1378/chest.70.2.259subject
Has Abstractpub_date
1976-08-01 00:00:00pages
259-62issue
2eissn
0012-3692issn
1931-3543pii
S0012-3692(16)53315-7journal_volume
70pub_type
杂志文章相关文献
CHEST文献大全abstract:BACKGROUND:During most of the cruise, submarines are detached from their environment. Therefore, O(2) levels are relatively low (19 kPa, 144 mm Hg) and CO(2) levels are high (1 kPa, 7.6 mm Hg). There are, however, periods during ventilation of the submarine in which CO(2) levels drop and O(2) levels increase. The objec...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.124.5.1716
更新日期:2003-11-01 00:00:00
abstract:BACKGROUND:Critically ill patients who develop ARDS have substantial associated morbidity and mortality. Circulating mitochondrial DNA (mtDNA) released during critical illness causes endothelial dysfunction and lung injury in experimental models. This study hypothesized that elevated plasma mtDNA is associated with ARD...
journal_title:Chest
pub_type: 杂志文章
doi:10.1016/j.chest.2019.09.028
更新日期:2020-01-01 00:00:00
abstract::Over a 20-year period, 83 patients underwent operative pleurodesis with resection of pulmonary blebs for spontaneous pneumothorax. Follow-up for all patients was between 5 and 25 years, with a mean of 9.1 years. There were five early (5.6 percent) and three late recurrences (3.6 percent). There were no deaths or need ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.104.6.1767
更新日期:1993-12-01 00:00:00
abstract::Immunoblastic lymphadenopathy presents with fever, malaise, cough, dyspnea, lymphadenopathy, hepatosplenomegaly, hypergammaglobulinemia, interstitial pulmonary infiltrates, mediastinal adenopathy, and effusions. The diagnosis is made on the basis of lymph node biopsy. Based on the course in our patients and the cases ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.80.3.312
更新日期:1981-09-01 00:00:00
abstract:BACKGROUND:Current functional assessments do not allow a reliable assessment of small airways, which are a major site of disease in COPD. Single-breath washout (SBW) tests are feasible and reproducible methods for evaluating small airway disease. Their relevance in COPD remains unknown. METHODS:We performed a cross-se...
journal_title:Chest
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.chest.2016.05.019
更新日期:2016-11-01 00:00:00
abstract::Significant eosinophilia is a prominent feature in Churg-Strauss syndrome but has only rarely been described in Wegener's granulomatosis (WG). We describe two Wegener's granulomatosis patients with > 30% eosinophilia on their initial presentations. Other etiologies that could account for their eosinophilia were exclud...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.116.5.1480
更新日期:1999-11-01 00:00:00
abstract:BACKGROUND:There are several reports showing that expiratory muscle strength and endurance can be impaired in patients with COPD. This muscle weakness may have clinically relevant implications. Expiratory muscle training tended to improve cough and to reduce the sensation of respiratory effort during exercise in patien...
journal_title:Chest
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1378/chest.124.2.468
更新日期:2003-08-01 00:00:00
abstract:BACKGROUND:Childhood OSA is a prevalent condition associated with raised BP as documented in cross-sectional studies. This study aimed to determine whether baseline or change in OSA severity was associated with ambulatory BP at 4-year follow-up. METHODS:Children who participated in our previous OSA prevalence research...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.13-1333
更新日期:2014-06-01 00:00:00
abstract::In experimental animals, conditions which drastically decrease cardiac output may reduce the strength and endurance of respiratory muscles leading to hypercapnic respiratory failure. Because patients with chronic CHF have reduced cardiac output and vital capacity (FVC), we measured PImax and PEmax and maximal handgrip...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.98.5.1091
更新日期:1990-11-01 00:00:00
abstract::This prospective study was conducted to describe the signs on transesophageal echocardiography (TEE) associated with traumatic aortic injury (TAI). Twenty-eight patients with TAI underwent TEE, and they were compared with a control group of 30 thoracic trauma patients without aortic injury. The TEE signs were classifi...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.112.1.71
更新日期:1997-07-01 00:00:00
abstract::Pulmonary disease due to talc, a group of hydrous magnesium silicates, is almost exclusively encountered after occupational exposure. One form of this rare disorder is talc granulomatosis. In varying degrees, hypercalcemia is typical of granulomatous disease but has not yet been reported in talcosis. We report the cas...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.117.4.1195
更新日期:2000-04-01 00:00:00
abstract::This commentary heralds the recognition in China of a new subspecialty, Pulmonary and Critical Care Medicine, and the first national fellowship training pathway in any medical specialty. Because of striking environmental health-care similarities that existed in the United States, the Chinese medical community decided ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.13-2082
更新日期:2014-01-01 00:00:00
abstract::Mucociliary clearance (MCC) is one of the most important nonspecific defense mechanisms of the respiratory tract, and its impairment is a well-documented feature of chronic respiratory diseases, including asthma. In vitro and in vivo data suggest that several inflammatory mediators influence the mucociliary apparatus....
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1378/chest.118.4.1142
更新日期:2000-10-01 00:00:00
abstract::The aim of the study was to compare (1) the intensity of leg effort and dyspnea during exercise and (2) subjective limitations to performance in normal subjects, patients receiving medication for cardiac disorders, patients with pulmonary impairment, patients with pulmonary impairment who were also receiving cardiac m...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.110.5.1255
更新日期:1996-11-01 00:00:00
abstract:OBJECTIVES:In California, state law now prohibits smoking in most public places. We examined the prevalence and short-term health impact of environmental tobacco smoke (ETS) exposure during travel among adults with asthma. DESIGN, SETTING, AND PARTICIPANTS:A cohort of 374 nonsmoking adults with asthma recruited from a...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.122.3.826
更新日期:2002-09-01 00:00:00
abstract:BACKGROUND:A novel approach to estimate the severity of COPD exacerbation and predict its outcome is the use of biomarkers. We assessed circulating levels of copeptin, the precursor of vasopressin, C-reactive protein (CRP), and procalcitonin as potential prognostic parameters for in-hospital and long-term outcomes in p...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.06-2336
更新日期:2007-04-01 00:00:00
abstract::A 79-year-old woman in the course of a syncope evaluation is shown to have a trazodone-related cardiac arrhythmia confirmed by drug rechallenge. This nontricyclic antidepressant should be considered as potentially arrhythmogenic despite its generally favorable cardiovascular profile. ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.98.1.247
更新日期:1990-07-01 00:00:00
abstract:BACKGROUND:Combination therapy with inhaled corticosteroids (ICSs) and long-acting beta(2)-agonists (LABAs), or treatment with high doses of ICSs alone improves asthma control when therapy with low-dose ICSs is not sufficient. However, it is not known which of these treatment options is more effective in sustaining ast...
journal_title:Chest
pub_type: 杂志文章,随机对照试验
doi:10.1378/chest.08-1018
更新日期:2008-12-01 00:00:00
abstract:STUDY OBJECTIVE:To evaluate the incidence and clinical factors related to the persistence of infarct-associated pericardial effusion (PE) after primary angioplasty. DESIGN:Consecutive case-series analysis. SETTING:Coronary care unit in a university hospital. PATIENTS:Three hundred ninety-one consecutive patients wit...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.128.2.798
更新日期:2005-08-01 00:00:00
abstract:STUDY OBJECTIVES:Pacing-induced asynchrony may deteriorate left ventricular function; however, limited data exists in humans. The aim of our study was to compare left ventricular hemodynamics during short-term atrioventricular sequential pacing from the right ventricular apex and from the outflow tract of the right ven...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.117.1.60
更新日期:2000-01-01 00:00:00
abstract::Postmortem examination two weeks following implantation of a demand pacemaker with sutureless electrodes demonstrated that (1) the loops of intrapericardial electrode leads indented the myocardium and produced a circumscribed area of subepicardial necrosis, and (2) one of the electrode coils protruded into the right v...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.70.1.80
更新日期:1976-07-01 00:00:00
abstract::Forty-eight children with known asthma (ranging in age from 2 to 16 years) were studied during an acute attack. Each received either terbutaline or epinephrine subcutaneously in a random double-blind fashion. Measurement of heart rate, respiratory rate, and systemic arterial systolic and diastolic blood pressures and ...
journal_title:Chest
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1378/chest.72.5.614
更新日期:1977-11-01 00:00:00
abstract::The incidence of distal esophageal adenocarcinoma and primary proximal gastric carcinoma has increased substantially in the past 15 years, particularly in North America and in some European countries. Patients with curatively resected cancer consistently have a 10 to 20% 5-year survival rate. Radiation therapy alone s...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1378/chest.113.1_supplement.112s
更新日期:1998-01-01 00:00:00
abstract::A 41-year-old man was found to have a miliary infiltrate on chest roentgenogram two months after recovery from varicella pneumonia. The patient remained in good health and there was no objective sign of pulmonary disease. The infiltrate showed no change in subsequent serial chest films, and after one year, open lung b...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.89.3.457
更新日期:1986-03-01 00:00:00
abstract:STUDY OBJECTIVES:To determine whether the quantitative evaluation of hemomediastinum using transesophageal echocardiography (TEE) is predictive of the presence of a traumatic disruption of the thoracic aorta (TDA) or its branches in patients who have sustained severe blunt chest trauma. DESIGN:Retrospective study. SE...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.113.6.1475
更新日期:1998-06-01 00:00:00
abstract:OBJECTIVE:This study applies a stochastic or probability search and display model to prospectively predict outcome and to evaluate therapeutic effects in a consecutively monitored series of 396 patients with severe thoracic and thoracoabdominal injuries. STUDY DESIGN:Prospective observational study of outcome predicti...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.128.4.2739
更新日期:2005-10-01 00:00:00
abstract::Results of preoperative pulmonary function tests were evaluated in 106 patients who had major thoracic or upper abdominal cardiovascular surgery. These results were related to the occurrence of postoperative complications by comparison of pulmonary function data in patients with an ICU stay of less than 5 days versus ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.76.2.130
更新日期:1979-08-01 00:00:00
abstract:STUDY OBJECTIVES:We sought to determine the indicators of asthma severity among children in the United States with high and low levels of tobacco smoke exposure. DESIGN:Cross-sectional study. SETTING:Nationally representative survey of participants in the Third National Health and Nutrition Examination Survey (from 1...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.122.2.409
更新日期:2002-08-01 00:00:00
abstract::We studied the possibility of predicting PaO2 during exercise of a given oxygen uptake (VO2) from resting pulmonary function tests (PFTs) in patients with chronic obstructive pulmonary disease (COPD). The three-minute incremental treadmill exercise was performed with serial measurements of PaO2 via intra-arterial cath...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.91.3.328
更新日期:1987-03-01 00:00:00
abstract::Previous studies on the bronchodilating effect of nitrates yielded conflicting results. We hypothesized that the concomitant bronchial vasodilatation induced by nitrates may limit the increase of airway patency due to bronchial smooth muscle relaxation. To test this hypothesis, we evaluated the bronchodilating effect ...
journal_title:Chest
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1378/chest.107.1.169
更新日期:1995-01-01 00:00:00