Therapeutic potential of mesenchymal stem cells for severe acute lung injury.

abstract：:To determine if a regimen of intravenous and oral corticosteroids reduces the relapse rate after treatment of decompensated COPD in the ED, 30 patients were studied. Forty-five visits in which intravenous and oral corticosteroids were given (T visits) were compared with an equal number of matched visits in which they ...

journal_title：Chest

authors： Murata GH,Gorby MS,Chick TW,Halperin AK

更新日期：1990-10-01 00:00:00

abstract：:Proximal pulmonary artery aneurysms (PAAs) are rare. Most are associated with secondary pulmonary hypertension or a variety of rare systemic disorders. An asymptomatic adult patient presented with bilateral hilar enlargement on a routine chest roentgenogram. Computed tomography of the chest revealed 5 cm bilateral pro...

journal_title：Chest

authors： Girgis R,Kavuru MS,Miller M,Spizarny D

更新日期：1992-07-01 00:00:00

abstract：OBJECTIVES:To measure tumor necrosis factor-alpha (TNF-alpha) and interleukin-1beta (IL-1beta) in pleural effusions caused by tuberculosis (TB) and malignancy and their relationship with plasminogen activator inhibitor type I (PAI-1) and tissue type plasminogen activator (tPA), and to compare the differences between tu...

journal_title：Chest

authors： Hua CC,Chang LC,Chen YC,Chang SC

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND:Clinicians lack a validated tool for risk stratification in acute exacerbations of COPD (AECOPD). We sought to validate the BAP-65 (elevated BUN, altered mental status, pulse > 109 beats/min, age > 65 years) score for this purpose. METHODS:We analyzed 34,699 admissions to 177 US hospitals (2007) with either...

journal_title：Chest

authors： Shorr AF,Sun X,Johannes RS,Yaitanes A,Tabak YP

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:To develop and compare ICU length-of-stay (LOS) risk-adjustment models using three commonly used mortality or LOS prediction models. METHODS:Between 2001 and 2004, we performed a retrospective, observational study of 11,295 ICU patients from 35 hospitals in the California Intensive Care Outcomes Project. We...

journal_title：Chest

authors： Vasilevskis EE,Kuzniewicz MW,Cason BA,Lane RK,Dean ML,Clay T,Rennie DJ,Vittinghoff E,Dudley RA

更新日期：2009-07-01 00:00:00

abstract：:Hospitalizations for patients with acute exacerbations of COPD are associated with several adverse patient outcomes as well as with significant health-care costs. Despite many interventions targeted at reducing readmissions following an initial hospitalization, there are few strategies that have been consistently asso...

journal_title：Chest

authors： Freedman N

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Pleuroparenchymal fibroelastosis (PPFE) is a rare form of interstitial pneumonia and sometimes coexists with a histologic usual interstitial pneumonia (UIP) pattern. This study aimed to describe the distinct clinical features of PPFE with UIP pattern compared with idiopathic pulmonary fibrosis (IPF). METHOD...

journal_title：Chest

authors： Oda T,Ogura T,Kitamura H,Hagiwara E,Baba T,Enomoto Y,Iwasawa T,Okudela K,Takemura T,Sakai F,Hasegawa Y

更新日期：2014-11-01 00:00:00

abstract：:An unusual case of essential thrombocythemia in a young man presenting with progressive angina pectoris is presented. Angiography revealed proximal left anterior descending artery stenosis. Successful percutaneous transluminal angioplasty along with antiplatelet therapy and a calcium channel blocking drug have rendere...

journal_title：Chest

authors： Hanger KH Jr,Kilgore J,James E

更新日期：1984-12-01 00:00:00

abstract：:Metastatic disease involving the heart may present in a variety of fashions. A patient with melanoma metastatic to the right ventricle which was diagnosed clinically by evidence of recent onset of right ventricular inflow and outflow tract obstruction is described. Important information regarding the extent of the met...

journal_title：Chest

authors： Emmot WW,Vacek JL,Agee K,Moran J,Dunn MI

更新日期：1987-08-01 00:00:00

abstract：OBJECTIVE:To determine the utility of inhaled hypertonic saline solution to treat infants hospitalized with viral bronchiolitis. DESIGN:Randomized, double-blind, controlled trial. Fifty-two hospitalized infants (mean +/- SD age, 2.9 +/- 2.1 months) with viral bronchiolitis received either inhalation of epinephrine, 1....

journal_title：Chest

authors： Mandelberg A,Tal G,Witzling M,Someck E,Houri S,Balin A,Priel IE

更新日期：2003-02-01 00:00:00

abstract：:Seventy-two healthy young individuals were subjected to controlled, moderate hyperventilation with room air and with 4.9 percent CO2 in air, and monitored electrocardiographically. Significant summed frontal T-wave changes with hyperventilation (sigmaT1,2,3 larger than or equal to 1.5 mm) were observed in 12 patients....

journal_title：Chest

authors： Golden GS,Golden LH,Beerel FR

更新日期：1975-01-01 00:00:00

abstract：:In rabbits, an experimental model of fat embolism was produced that simulates the course of events in the clinical situation. Small doses of fat-cell suspension (0.075 ml/kg of body weight), prepared by collagenase treatment of homologous adipose tissue, were injected intravenously. Concomitantly, hypovolemia was prod...

journal_title：Chest

authors： Cotev S,Rosenmann E,Eyal Z,Weinberg H,Shafrir E,Davidson JT

更新日期：1976-04-01 00:00:00

abstract：BACKGROUND:Small cell lung carcinoma (SCLC) continues to have a poor prognosis, with a 2-year survival of < 20%. Studies have suggested that SCLC may affect the immune system to allow it to evade immunologic responses. We hypothesized that any such effect would be characterized by a decrease in the lymphoid cells assoc...

journal_title：Chest

authors： Wang W,Hodkinson P,McLaren F,Mackean MJ,Williams L,Howie SEM,Wallace WAH,Sethi T

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Obstructive sleep apnea (OSA) is a highly prevalent disorder that has been associated with an increased risk for cardiovascular morbidity, even in children. However, not all children with OSA manifest alterations in endothelial postocclusive hyperemia, an endothelial nitric oxide synthase (eNOS)-dependent re...

journal_title：Chest

authors： Kheirandish-Gozal L,Khalyfa A,Gozal D,Bhattacharjee R,Wang Y

更新日期：2013-04-01 00:00:00

abstract：:alpha 1-Antitrypsin (alpha 1-AT) accumulates in the rough endoplasmic reticulum through a mechanism of polymerization. Polymerization is favored by the incorrect tertiary structure of the alpha 1-AT caused by a point mutation at position 342 of the protein. Accumulation of alpha 1-AT in the liver cells (and in hepatoc...

journal_title：Chest

authors： Massi G

更新日期：1996-12-01 00:00:00

abstract：:Serum levels of a high molecular weight circulating antigen KL-6, detected by means of a sandwich assay using a monoclonal antibody KL-6 against a sialylated carbohydrate antigen, were evaluated for usefulness in monitoring the activity of interstitial pneumonitis. Abnormally high levels of KL-6 antigen were observed ...

journal_title：Chest

authors： Kohno N,Kyoizumi S,Awaya Y,Fukuhara H,Yamakido M,Akiyama M

更新日期：1989-07-01 00:00:00

abstract：:Cough and wheezing are frequent side effects of inhaling beclomethasone dipropionate aerosol (BA) in patients with asthma. Twenty percent of our outpatient asthmatic subjects are unable to take BA due to these side effects. Twelve patients with history of severe cough and wheezing after inhaling BA were tested. Three ...

journal_title：Chest

authors： Shim C,Williams MH Jr

更新日期：1987-02-01 00:00:00

abstract：OBJECTIVE:Congenital airway malacia is one of the few causes of irreversible airways obstruction in children, but the incidence in the general population is unknown. Severe airway malacia or malacia associated with specific syndromes is usually recognized and diagnosed early in infancy, but information about clinical f...

journal_title：Chest

authors： Boogaard R,Huijsmans SH,Pijnenburg MW,Tiddens HA,de Jongste JC,Merkus PJ

更新日期：2005-11-01 00:00:00

abstract：STUDY OBJECTIVES:We sought to determine the adaptability and effectiveness of a new esophageal balloon technique to measure changes in esophageal pressure (Pes) as a reflection of pleural pressure with progressive incremental exercise testing in normal subjects. DESIGN:An 8F (0.9 cm) esophageal balloon catheter (Smart...

journal_title：Chest

authors： Thomas AM,Turner RE,Tenholder MF

更新日期：1997-09-01 00:00:00

abstract：:The mechanisms leading to rapid changes in arterial blood gas values soon after exercise ends have not been well established. To further study these phenomena, we exercised seven normal male volunteers to exhaustion on a cycle ergometer with a 25-W/min ramped protocol measuring arterial blood gas values, and breath-by...

journal_title：Chest

authors： O'Neill AV,Johnson DC

更新日期：1991-05-01 00:00:00

abstract：OBJECTIVE:To determine the contribution of the various components of a rehabilitation program to the improvement of exercise capacity and health-related quality of life (HRQL) in patients with COPD. DATA SOURCES:MEDLINE (1966 to April 1996) was searched. Abstracts presented at international conferences were also hand ...

journal_title：Chest

authors： Lacasse Y,Guyatt GH,Goldstein RS

更新日期：1997-04-01 00:00:00

abstract：:Eradication of the bacterial pathogen, resolution of the local and systemic inflammatory signs, and recovery of organ function are the main criteria by which antibiotic treatment is evaluated. In cystic fibrosis (CF) the pathogen is seldom eradicated and systemic markers of inflammation are not always present. The mai...

journal_title：Chest

authors： Levy J

更新日期：1988-08-01 00:00:00

abstract：BACKGROUND:Among patients awaiting cadaveric lung transplantation, patients with idiopathic interstitial pneumonia (IIP) have been demonstrated to have the highest mortality rate. Contraindications to cadaveric lung transplantation include current high-dose systemic corticosteroid therapy because it may increase airway...

journal_title：Chest

authors： Date H,Tanimoto Y,Goto K,Yamadori I,Aoe M,Sano Y,Shimizu N

更新日期：2005-09-01 00:00:00

abstract：:A case of idiopathic pulmonary hypertension is associated with portal venous thrombosis. The patient's chest roentgenogram revealed numerous nodular densities which at necropsy were found to have been caused by an exuberant fibroblastic reaction around small pulmonary arterioles. This is an example of the unusual asso...

journal_title：Chest

authors： Bower JS,Dantzker DR,Naylor B

更新日期：1980-07-01 00:00:00

abstract：STUDY OBJECTIVES:It has been suggested that sleep-disordered breathing (SDB) is a risk factor for ischemic heart disease, and may be associated with increased morbidity and mortality due to cardiovascular disease. The aim of this study was to examine the relation between nocturnal oxygen desaturation (NOD) due to SDB a...

journal_title：Chest

authors： Hayashi M,Fujimoto K,Urushibata K,Uchikawa S,Imamura H,Kubo K

更新日期：2003-09-01 00:00:00

abstract：:Pulmonary function studies were conducted one to two days prior to, two weeks after, and an average of 116 days after coronary artery revascularization surgery. Preoperation it was found that 11 of 19 patients had mild to moderate obstruction, 8 of 17 had diffusing capacity less than 80 percent of predicted, and 9 of ...

journal_title：Chest

authors： Braun SR,Birnbaum ML,Chopra PS

更新日期：1978-03-01 00:00:00

abstract：STUDY OBJECTIVES:Direct current (DC) shocks to the heart cause morphologic and functional myocardial damage. Previous studies have suggested that acute DC shock injury is free radical mediated and that the administration of antioxidant enzymes superoxide dismutase and catalase can reduce the level of DC shock-induced f...

journal_title：Chest

authors： Pagan-Carlo LA,Garcia LA,Hutchison JL,Buettner GR,Kerber RE

更新日期：1999-08-01 00:00:00

abstract：CASE PRESENTATION:A 32-year-old man presented with fever, nonproductive cough, diffuse lymphadenopathy, and polyarticular pain for 2 weeks. His medical history included HIV diagnosed 10 years ago, anal intraepithelial neoplasia, Kaposi sarcoma, and herpes simplex virus-2 infection. The patient was not receiving antiret...

journal_title：Chest

authors： Xian JZ,Cherian SV,Golardi N,Estrada-Y-Martin RM

更新日期：2018-11-01 00:00:00

abstract：STUDY OBJECTIVES:To determine whether the nuclear accumulation of p53 in patients with early bronchial neoplasia represents an altered susceptibility for the development of lung cancer. PATIENTS AND MEASUREMENTS:We evaluated the percentage of cells accumulating nuclear p53 immunohistochemically in squamous cell carcin...

journal_title：Chest

authors： Piyathilake CJ,Frost AR,Manne U,Weiss H,Heimburger DC,Grizzle WE

更新日期：2003-01-01 00:00:00

abstract：:The coronary arteriogram of a 52-year-old man with Basedow's disease and who was suffering from myocardial infarction following rapid atrial fibrillation, showed severe myocardial squeezing without organic stenosis. Angiographically, the functional obstructive lesion was always observed both at systole and diastole du...

journal_title：Chest

authors： Endo M,Lee YW,Hayashi H,Wada J

更新日期：1978-03-01 00:00:00