Cough and wheezing from beclomethasone aerosol.

Abstract:

:Cough and wheezing are frequent side effects of inhaling beclomethasone dipropionate aerosol (BA) in patients with asthma. Twenty percent of our outpatient asthmatic subjects are unable to take BA due to these side effects. Twelve patients with history of severe cough and wheezing after inhaling BA were tested. Three puffs of either BA or placebo (Plc) were administered from a metered dose inhaler (MDI) in a double-blind crossover design. They coughed a mean of 31 times after BA and 19 times after Plc. Forced expiratory volume in one sec (FEV1) declined a mean of 22.6 percent after BA and 22.0 percent after Plc. Pretreatment with albuterol attenuated both the cough and the drop in FEV1. Follow-up study showed that regular pretreatment with bronchodilator enabled seven of 12 patients to tolerate BA therapy. The remaining five required a short course of increased dose oral steroid therapy. Cough and wheezing are frequent side effects of BA therapy that interfere with regular compliance. Pretreatment with a bronchodilator is effective in attenuating these side effects in some patients; in others, a short course of oral steroid therapy may be necessary.

journal_name

Chest

journal_title

Chest

authors

Shim C,Williams MH Jr

doi

10.1378/chest.91.2.207

subject

Has Abstract

pub_date

1987-02-01 00:00:00

pages

207-9

issue

2

eissn

0012-3692

issn

1931-3543

pii

S0012-3692(16)47313-7

journal_volume

91

pub_type

临床试验,杂志文章

相关文献

CHEST文献大全
  • Genetics of asthma and COPD. Similar results for different phenotypes.

    abstract::Asthma and COPD are common respiratory diseases that are caused by the interaction of genetic susceptibility with environmental factors. Environmental influences are important in both diseases, and although there are differences in genetic susceptibilities, there are also similarities. Three examples of interest for b...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.126.2_suppl_1.105S

    authors: Meyers DA,Larj MJ,Lange L

    更新日期:2004-08-01 00:00:00

  • Genetics and pulmonary hypertension.

    abstract::Primary pulmonary hypertension (PPH) is a serious pulmonary vascular disease occurring mostly in adult women. Although its occurrence in families was reported within a few years after the original clinical report, PPH was formerly believed rarely to have a genetic basis. Recent progress has not only clarified a basic ...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.122.6_suppl.284s

    authors: Loyd JE

    更新日期:2002-12-01 00:00:00

  • Doxycycline pleurodesis for pneumothorax in patients with AIDS.

    abstract::Since first described in 1984, nontraumatic pneumothoraces in patients with AIDS has become more common. When compared with spontaneous pneumothorax in the general population, pneumothoraces in patients with AIDS are often complicated by prolonged air leaks as well as higher recurrence rates. Chemical pleurodesis has ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.105.3.823

    authors: Read CA,Reddy VD,O'Mara TE,Richardson MS

    更新日期:1994-03-01 00:00:00

  • Early post-pneumonectomy bronchial stump fistula.

    abstract::Bronchial stump fistula occurred on the seventh postoperative day in a 45-year-old man who underwent right pneumonectomy for T2N2M0 adenocarcinoma of the lung. It was attributable to ventilator-related barotrauma during treatment of ARDS from multiple pulmonary emboli. A frequently lethal complication, its presentatio...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.93.3.654

    authors: Pomerantz AH,Derasari MD,Sethi SS,Khan S

    更新日期:1988-03-01 00:00:00

  • High-Flow Nasal Cannula in the Immediate Postoperative Period: A Systematic Review and Meta-analysis.

    abstract:BACKGROUND:Studies have demonstrated that high-flow nasal cannula (HFNC) prevents intubation in acute hypoxic respiratory failure when compared with conventional oxygen therapy (COT). However, the data examining routine HFNC use in the immediate postoperative period are less clear. RESEARCH QUESTION:Is routine HFNC us...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1016/j.chest.2020.06.038

    authors: Chaudhuri D,Granton D,Wang DX,Burns KEA,Helviz Y,Einav S,Trivedi V,Mauri T,Ricard JD,Mancebo J,Frat JP,Jog S,Hernandez G,Maggiore SM,Mbuagbaw L,Hodgson CL,Jaber S,Goligher EC,Brochard L,Rochwerg B

    更新日期:2020-11-01 00:00:00

  • Nasal function and bronchial hyperresponsiveness to methacholine in children.

    abstract::The objective of the present study was to investigate nasal function by active anterior rhinomanometry with respect to spirometric data and bronchial hyperresponsiveness to methacholine in 9-year-old children. The study population consisted of 300 children (ages 8 to 11 years; mean, 9.3 years; 161 male, 139 female), w...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.107.6.1582

    authors: Kiss D,Popp W,Horak F,Wagner C,Zwick H

    更新日期:1995-06-01 00:00:00

  • High altitude pulmonary edema and exercise at 4,400 meters on Mount McKinley. Effect of expiratory positive airway pressure.

    abstract::Breathing against positive expiratory pressure has been used to improve gas exchange in many forms of pulmonary edema, and forced expiration against resistance during exercise has been advocated for climbing at high altitude as a method to optimize performance. To evaluate the effect of expiratory positive airway pres...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.87.3.330

    authors: Schoene RB,Roach RC,Hackett PH,Harrison G,Mills WJ Jr

    更新日期:1985-03-01 00:00:00

  • Retreatment of recurrent invasive thymoma with platinum, doxorubicin, and cyclophosphamide.

    abstract::Invasive thymoma recently has been shown to be sensitive to combination chemotherapy and in some cases to be relatively indolent. Two cases of extensive thymoma which responded to primary treatment with a combination of a platinum compound (carboplatin or cisplatin), doxorubicin (Adriamycin), and cyclophosphamide (or ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.110.4.1115

    authors: Lara PN Jr,Bonomi PD,Faber LP

    更新日期:1996-10-01 00:00:00

  • Formoterol, 24 microg bid, and serious asthma exacerbations: similar rates compared with formoterol, 12 microg bid, with and without extra doses taken on demand, and placebo.

    abstract:STUDY OBJECTIVES:The primary objective was to determine whether high-dose formoterol, 24 mug bid, was associated with more asthma exacerbations compared with lower formoterol doses in patients with stable persistent asthma. Serious asthma exacerbations (life threatening or requiring hospitalization) were the primary en...

    journal_title:Chest

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1378/chest.129.1.27

    authors: Wolfe J,Laforce C,Friedman B,Sokol W,Till D,Della Cioppa G,van As A

    更新日期:2006-01-01 00:00:00

  • Radiographic fibrosis score predicts survival in hypersensitivity pneumonitis.

    abstract:BACKGROUND:It is unknown if the radiographic fibrosis score predicts mortality in persistent hypersensitivity pneumonitis (HP) and if survival is similar to that observed in idiopathic pulmonary fibrosis (IPF) when adjusting for the extent of radiographic fibrosis. METHODS:We reviewed records from 177 patients with HP...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.12-2623

    authors: Mooney JJ,Elicker BM,Urbania TH,Agarwal MR,Ryerson CJ,Nguyen MLT,Woodruff PG,Jones KD,Collard HR,King TE Jr,Koth LL

    更新日期:2013-08-01 00:00:00

  • Palliative Care in Advanced Lung Disease: The Challenge of Integrating Palliation Into Everyday Care.

    abstract::The tendency toward "either/or" thinking (either cure or comfort) in traditional biomedical care paradigms does little to optimize care in advancing chronic illness. Calls for improved palliation in chronic lung disease mandate a review of related care gaps and current clinical practices. Although specialist palliativ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.14-2593

    authors: Rocker GM,Simpson AC,Horton R

    更新日期:2015-09-01 00:00:00

  • Measurement of surface temperature in lung cancer.

    abstract::We measured the surface temperature of the tumors in 27 patients with primary lung cancer, using a flexible bronchofiberscope and a thermometer made from chromel-constantan. The thermometer was inserted into the aspiration channel of the bronchofiberscope, and temperature was studied under bronchofiberscopic located i...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.81.1.62

    authors: Ohgimi T,Akiyama S,Shimokata K

    更新日期:1982-01-01 00:00:00

  • The inescapable relevance of bioethics for the practicing clinician.

    abstract:KEY POINTS:1. Historically, medical ethics focused on the proper conduct of physicians as members of a profession. 2. Bioethics has emerged as a distinct field over the past several decades and has a broader scope than traditional medical ethics. The field of bioethics includes research ethics, public health ethics, or...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.130.6.1864

    authors: Carrese JA,Sugarman J

    更新日期:2006-12-01 00:00:00

  • Radiation effect on implanted pacemakers.

    abstract::It was previously thought that diagnostic or therapeutic ionizing radiation did not have an adverse effect on the function of cardiac pacemakers. Recently, however, some authors have reported damaging effect of the therapeutic radiation on cardiac pulse generators. An analysis of a recently-extracted pacemaker documen...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.84.4.499

    authors: Pourhamidi AH

    更新日期:1983-10-01 00:00:00

  • Vascular endothelial growth factor and the risk of smoking-related COPD.

    abstract:STUDY OBJECTIVES:Vascular endothelial growth factor (VEGF) signaling may be required for maintenance of the alveolar structures, and alveolar septal cell apoptosis could contribute to the pathogenesis of COPD presenting emphysematous changes; however, the common mutation at position 936 in the 3' untranslated region of...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.124.1.323

    authors: Sakao S,Tatsumi K,Hashimoto T,Igari H,Shino Y,Shirasawa H,Kuriyama T

    更新日期:2003-07-01 00:00:00

  • Dieulafoy's disease of the bronchus in association with a paravertebral neurilemoma.

    abstract::Dieulafoy's disease is a vascular anomaly characterized by the presence of a dysplastic artery that is related to an epithelial ulcer. While it is most frequently a GI condition, occurrence in the bronchus has been reported previously in six cases. We present the case of a 51-year-old man with severe hemoptysis and ep...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.119.1.292

    authors: Stoopen E,Baquera-Heredia J,Cortes D,Green L

    更新日期:2001-01-01 00:00:00

  • The prevalence of exercise-induced bronchospasm among US Army recruits and its effects on physical performance.

    abstract:STUDY OBJECTIVES:To measure the prevalence of exercise-induced bronchospasm (EIB) and to determine its effect on the physical performance response to training in otherwise healthy young adults. DESIGN:Observational, retrospective study. SETTING:Fort Jackson, SC, May to July 1998. PARTICIPANTS:One hundred thirty-seve...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.119.6.1676

    authors: Sonna LA,Angel KC,Sharp MA,Knapik JJ,Patton JF,Lilly CM

    更新日期:2001-06-01 00:00:00

  • Pulmonary vascular disease in secundum atrial septal defect with pulmonary hypertension.

    abstract::Histopathologic and morphometric studies of small pulmonary arteries were performed in 16 cases of secundum atrial septal defect (ASD) and severe pulmonary hypertension. Besides typical plexogenic arteriopathies found in six cases, organized microthrombi and what we call "musculoelastosis," that is, proliferation of l...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.89.5.694

    authors: Yamaki S,Horiuchi T,Miura M,Suzuki Y,Ishizawa E,Takahashi T

    更新日期:1986-05-01 00:00:00

  • Periodic breathing with no heart beat.

    abstract::A protocol was originally designed to study breathing control during and following cardiac arrest in humans, taking advantage of the period of pulseless ventricular fibrillation (PVF) produced while testing a newly implanted cardioverter-defibrillator device. A patient aged in his 60s with New York Heart Association c...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.12-2950

    authors: Bartsch S,Haouzi P

    更新日期:2013-10-01 00:00:00

  • Comparison of intravenous and inhaled terbutaline in the treatment of asthma.

    abstract::In a double-blind crossover controlled study, intravenous (IV) or nebulized terbutaline was given to eight patients with moderately severe asthma on two separate days. Four incremental doses of terbutaline were given by each route to establish a maximal effect. Both routes of administration produced significant increa...

    journal_title:Chest

    pub_type: 临床试验,杂志文章

    doi:10.1378/chest.79.5.506

    authors: Pierce RJ,Payne CR,Williams SJ,Denison DM,Clark TJ

    更新日期:1981-05-01 00:00:00

  • Inhaled furosemide is not effective in acute asthma.

    abstract::As previous studies have suggested that inhaled furosemide may have a protective effect against certain types of provocative challenges in asthmatic subjects, we investigated the role of furosemide in treating acute asthma exacerbations. Twenty-four patients (n = 24) with acute asthma were entered into the study on pr...

    journal_title:Chest

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1378/chest.106.5.1396

    authors: Karpel JP,Dworkin F,Hager D,Feliciano S,Shapiro D,Posner L,Luks D

    更新日期:1994-11-01 00:00:00

  • Interleukin-2 and soluble interleukin-2 receptor in bronchoalveolar lavage fluid from patients with bronchial asthma.

    abstract::To clarify the interrelation between interleukin-2 (IL-2) and soluble IL-2R receptor (sIL-2R), as products of T-cell activation in the bronchial tree of patients with bronchial asthma, we measured the concentration of IL-2, sIL-2R, and the cellular composition in bronchoalveolar lavage (BAL) fluid. We also measured ph...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.106.2.400

    authors: Park CS,Lee SM,Chung SW,Uh S,Kim HT,Kim YH

    更新日期:1994-08-01 00:00:00

  • Maximal sniff mouth pressure compared with maximal inspiratory pressure in acute respiratory failure.

    abstract::Inspiratory muscle strength most often is better reflected by sniff Pes than PImax against occlusion. Furthermore, sniff Pes can be estimated noninvasively by the measurement of sniff Pmo in normal subjects and in patients with respiratory muscle weakness. The aim of this study was to compare sniff Pmo and P.PImax to ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.100.1.175

    authors: Héritier F,Perret C,Fitting JW

    更新日期:1991-07-01 00:00:00

  • The effect of physical therapy on respiratory complications following cardiac valve surgery.

    abstract:STUDY OBJECTIVE:To determine whether higher personnel intensive chest physical therapy can prevent the atelectasis that routinely follows cardiac valve surgery. DESIGN:Randomized, controlled trial. SETTING:Tertiary care hospital. PATIENTS:Seventy-eight patients undergoing elective cardiac valve surgery between Octob...

    journal_title:Chest

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1378/chest.109.3.638

    authors: Johnson D,Kelm C,Thomson D,Burbridge B,Mayers I

    更新日期:1996-03-01 00:00:00

  • Naloxone and naltrexone. Application in COPD.

    abstract::The narcotic antagonists naloxone and naltrexone were used as respiratory stimulants in two patients failing traditional medical therapy for COPD. Both patients demonstrated improvement while receiving the drugs, but developed respiratory failure when they were discontinued abruptly. In selected patients with COPD, na...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.93.1.217

    authors: Reents SB,Beck CA Jr

    更新日期:1988-01-01 00:00:00

  • Contrast-enhanced sonography for differential diagnosis of pleurisy and focal pleural lesions of unknown cause.

    abstract:BACKGROUND:Ultrasound enables the visualization of pleural-based lesions with a poor correlation to specific pathology. At this time, there are no data about the diagnostic value of contrast-enhanced sonography (CES) in pleural lesions. METHODS:From August 2004 to January 2005, 25 consecutive patients with clinical sy...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.128.6.3894

    authors: Görg C,Bert T,Görg K

    更新日期:2005-12-01 00:00:00

  • Dyspnea in a patient years after severe poliomyelitis. The role of cardiopulmonary exercise testing.

    abstract::Dyspnea after polio can occur for a variety of reasons, including neuromuscular disease and upper airway abnormalities resulting from prolonged intubation, including tracheal stenosis, tracheomalacia, and vocal cord paralysis. Routine studies such as spirometry and maximum voluntary ventilation (MVV) measurements can ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.105.3.777

    authors: Knobil K,Becker FS,Harper P,Graf LB,Wolf GT,Martinez FJ

    更新日期:1994-03-01 00:00:00

  • Characteristics of airway inflammation and bronchodilator reversibility in COPD: a potential guide to treatment.

    abstract:STUDY OBJECTIVES:The management of stable patients with COPD depends on the severity of symptoms and airflow limitation. Regarding inflammation, corticosteroids are the only medications that are recommended for use, and only under restricted circumstances. Corticosteroids tend to undertreat or overtreat patients with C...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.126.2.375

    authors: Perng DW,Huang HY,Chen HM,Lee YC,Perng RP

    更新日期:2004-08-01 00:00:00

  • Advanced emphysema in African-American and white patients: do differences exist?

    abstract:BACKGROUND:Emphysema is the only smoking-related disease in which white patients have higher prevalence and higher attributable mortality rates than African-American patients. Epidemiologic studies have not addressed, nor explained, the observed racial differences in emphysema. STUDY OBJECTIVES:To determine whether wh...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.130.1.108

    authors: Chatila WM,Hoffman EA,Gaughan J,Robinswood GB,Criner GJ,National Emphysema Treatment Trial Research Group.

    更新日期:2006-07-01 00:00:00

  • Orthodeoxia platypnea syndrome in a patient with lipomatous hypertrophy of the interatrial septum due to long-term steroid use.

    abstract::We describe an unusual case of orthodeoxia platypnea syndrome exacerbated by right ventricular inflow obstruction due to iatrogenic steroid-induced adipose deposition in cardiac tissues. A 68-year-old man on long-term prednisone therapy for eosinophilic pneumonia presented with progressive dyspnea worsened by bending ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.10-0874

    authors: Bokhari SSI,Willens HJ,Lowery MH,Wanner A,deMarchena E

    更新日期:2011-02-01 00:00:00