Pre- and postoperative pulmonary function abnormalities in coronary artery revascularization surgery.


:Pulmonary function studies were conducted one to two days prior to, two weeks after, and an average of 116 days after coronary artery revascularization surgery. Preoperation it was found that 11 of 19 patients had mild to moderate obstruction, 8 of 17 had diffusing capacity less than 80 percent of predicted, and 9 of 17 had mild hypoxemia. Many of these abnormalities seemed related to smoking. After surgery, significant reductions in volumes, diffusion and PaO2 were found at two weeks. By the last study, there was improvement in volumes and diffusion, but they remained significantly reduced in comparison to preoperative levels. Arterial oxygen tension (PaO2) had returned to preoperative levels. Correction of diffusion for volume showed there to be no change in any of the study periods suggesting chest wall alteration is a major component of the abnormality. It is concluded that close monitoring of pulmonary function is indicated before and after operation in this patient population even if the patient is asymptomatic.






Braun SR,Birnbaum ML,Chopra PS




Has Abstract


1978-03-01 00:00:00
















  • Fluid balance during pulmonary edema. Is fluid gain a marker or a cause of poor outcome?

    abstract:STUDY OBJECTIVE:To evaluate the importance of fluid balance and changes in extravascular lung water (EVLW) on survival in the ICU and short-term outcome in patients with pulmonary edema. DESIGN:Retrospective analysis of data (sorting by survival and "treatment received") from a recent randomized controlled trial of fl...


    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Schuller D,Mitchell JP,Calandrino FS,Schuster DP

    更新日期:1991-10-01 00:00:00

  • Rheumatoid nodules in the trachea.

    abstract::We describe the first case of endotracheal rheumatoid nodules in a 45-year-old Chinese man with rheumatoid arthritis. He developed exacerbation of polyarthritis, new subcutaneous nodules and fibrosing alveolitis. At bronchoscopy, four whitish nodules were detected at the tracheal wall, and biopsy showed fibrinoid necr...


    pub_type: 杂志文章


    authors: Ip MS,Wong MP,Wong KL

    更新日期:1993-01-01 00:00:00

  • Negative pressure pulmonary edema following bronchospasm.

    abstract::Negative pressure pulmonary edema (NPPE) is an important cause of noncardiogenic pulmonary edema but is rarely reported in the setting of bronchospasm. A 43-year-old woman with severe reactive airway disease suffered an episode of severe bronchospasm after endotracheal extubation following an otherwise uneventful gene...


    pub_type: 杂志文章


    authors: Krodel DJ,Bittner EA,Abdulnour RE,Brown RH,Eikermann M

    更新日期:2011-11-01 00:00:00

  • Characteristics and outcomes of patients hospitalized following pulmonary aspiration.

    abstract:BACKGROUND:Pulmonary aspiration is an important recognized cause of ARDS. Better characterization of patients who aspirate may allow identification of potential risks for aspiration that could be used in future studies to mitigate the occurrence of aspiration and its devastating complications. METHODS:We conducted a s...


    pub_type: 杂志文章


    authors: Lee A,Festic E,Park PK,Raghavendran K,Dabbagh O,Adesanya A,Gajic O,Bartz RR,United States Critical Illness and Injury Trials Group.

    更新日期:2014-10-01 00:00:00

  • The hypotensive effect of L-arginine is associated with increased expired nitric oxide in humans.

    abstract::Endothelial metabolism of L-arginine to L-citrulline and the potent vasodilator, nitric oxide (NO), is important in the regulation of vascular tone and resting BP. L-arginine improves abnormal endothelium-dependent vasodilation in the setting of hypercholesterolemia and has a vasodilatory effect in normal vessels, eff...


    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Mehta S,Stewart DJ,Levy RD

    更新日期:1996-06-01 00:00:00

  • A 37-Year-Old Man With Pleuritic Chest Pain.

    abstract:CASE PRESENTATION:A 37-year-old man with poorly controlled type 2 diabetes presented with severe right-sided pleuritic chest pain, respiratory splinting, and cough. Two weeks earlier, he had been evaluated at an urgent care for cough and was prescribed a 5-day course of azithromycin for bronchitis. He then presented to...


    pub_type: 杂志文章


    authors: Galant-Swafford J,Light M,Onaitis MW,Rawlings SA,Fierer J,Landsberg JW

    更新日期:2019-07-01 00:00:00

  • Cancer genetics and cell and molecular biology. Is this the way forward?

    abstract::Lung cancer, the most prevalent cancer in the western world, is predominantly caused by smoking and thus perceived as a "self-inflicted" disease. Nevertheless, only 20% of smokers develop lung cancer. This review examines the concept of high-risk populations and screening. It looks at developments in the molecular epi...


    pub_type: 杂志文章


    authors: Smyth JF

    更新日期:1996-05-01 00:00:00

  • Increased ventricular ectopy and sleep apnea following ethanol ingestion in COPD patients.

    abstract::The effects were assessed of ingestion of 1 ml/kg of 100 proof vodka on sleep-disordered breathing, nocturnal oxygen desaturation, and ventricular ectopy in patients with chronic obstructive pulmonary disease (COPD). Ethanol ingestion (mean blood alcohol concentration of 40 mg/dl) was associated with a significant inc...


    pub_type: 杂志文章


    authors: Dolly FR,Block AJ

    更新日期:1983-03-01 00:00:00

  • Ventilator-associated pneumonia: impact of organisms on clinical resolution and medical resources utilization.

    abstract:BACKGROUND:Clinical resolution of ventilator-associated pneumonia (VAP) determines the duration of treatment and mechanical ventilation. The aim of this study was to evaluate the influence of organisms and their susceptibility to treatment on outcomes. METHODS:Prospective observational study in three teaching ICUs. Si...


    pub_type: 杂志文章


    authors: Vidaur L,Planas K,Sierra R,Dimopoulos G,Ramirez A,Lisboa T,Rello J

    更新日期:2008-03-01 00:00:00

  • Comparison of the bronchodilator effects of oral therapy with fenoterol hydrobromide and ephedrine.

    abstract::Fenoterol hydrobromide (Berotec; formerly Th 1165a) is a sympathomimetic bronchodilator drug. Twenty subjects with mild to moderate reversible bronchospasm completed a double-blind multiple crossover study of single doses of 5 mg, 7.5 mg, and 10 mg of fenoterol hydrobromide, 24 mg of ephedrine, and placebo. Spirometri...


    pub_type: 临床试验,杂志文章


    authors: Steen SN,Smith R,Kuo J,Ziment I,Beall G

    更新日期:1977-09-01 00:00:00

  • Outcome after right middle lobe syndrome.

    abstract::The long-term pulmonary consequences of right middle lobe syndrome (RMLS) in childhood are not known. Therefore, outcome was evaluated in 17 children with RMLS diagnosed in early childhood (mean age, 3.3 years; SD, 1.1 year). Mean age at follow-up was 10.1 years (SD, 2.6 years). RMLS was defined as atelectasis of the ...


    pub_type: 杂志文章


    authors: De Boeck K,Willems T,Van Gysel D,Corbeel L,Eeckels R

    更新日期:1995-07-01 00:00:00

  • Inhaled corticosteroid dose response using domiciliary exhaled nitric oxide in persistent asthma: the FENOtype trial.

    abstract:BACKGROUND:International guidelines advocate a standard approach to asthma management for all, despite its heterogeneity. "Personalized" treatment of inflammatory asthma phenotypes confers superior benefits. We wished to evaluate dose response to inhaled corticosteroids (ICSs) in patients with asthma with an elevated f...


    pub_type: 杂志文章,随机对照试验


    authors: Anderson WJ,Short PM,Williamson PA,Lipworth BJ

    更新日期:2012-12-01 00:00:00

  • Long-term outcome for obstructive sleep apnea syndrome patients. Mortality.

    abstract::As the actual mortality and morbidity of obstructive sleep apnea syndrome (OSAS) have been unknown heretofore, we undertook a follow-up study of 198 OSAS patients seen at the Stanford Sleep Disorders Clinic between 1972 and 1980, for whom either tracheostomy (71 patients) or weight loss (127 patients) had been recomme...


    pub_type: 杂志文章


    authors: Partinen M,Jamieson A,Guilleminault C

    更新日期:1988-12-01 00:00:00

  • Slow-release theophylline in pregnant asthmatics.

    abstract:STUDY OBJECTIVE:Oral theophylline treatment may be helpful in controlling severe asthma during pregnancy. This treatment, however, has been suspected of causing both complications and malformations. The objective of this investigation was to study the influence of theophylline treatment on the course of pregnancy and d...


    pub_type: 杂志文章


    authors: Stenius-Aarniala B,Riikonen S,Teramo K

    更新日期:1995-03-01 00:00:00

  • Radionuclide localization of massive pulmonary hemorrhage.

    abstract::Lung scans with technetium sulfur colloid were performed in ten patients with life-threatening hemoptysis and nondiagnostic chest roentgenograms. Localized deposition of radionuclide was demonstrated in five of the six patients who were studied during active bleeding. These abnormalities were confirmed bronchoscopical...


    pub_type: 杂志文章


    authors: Haponik EF,Rothfeld B,Britt EJ,Bleecker ER

    更新日期:1984-08-01 00:00:00

  • Lack of influence of gender on outcomes of mechanically ventilated medical ICU patients.

    abstract:STUDY OBJECTIVES:Recent studies combining medical and surgical patients have suggested that mortality is higher for mechanically ventilated women than for men. This study was designed to determine whether there are gender-based differences in outcomes in mechanically ventilated medical ICU (MICU) patients. DESIGN AND ...


    pub_type: 杂志文章


    authors: Epstein SK,Vuong V

    更新日期:1999-09-01 00:00:00

  • Clinical significance of fractional flow reserve for evaluation of functional lesion severity in stent restenosis and native coronary arteries.

    abstract:OBJECTIVE:Fractional flow reserve (FFR) is a valid surrogate for hemodynamic significance in stenotic native coronary arteries, but its validity in patients with coronary stent restenosis is unknown. DESIGN:Prospective. SETTING:University hospital. PATIENTS:We studied 42 patients (mean age +/- 1 SD, 62 +/- 10 years)...


    pub_type: 杂志文章


    authors: Krüger S,Koch KC,Kaumanns I,Merx MW,Hanrath P,Hoffmann R

    更新日期:2005-09-01 00:00:00

  • Clinical significance of low voltage in asymptomatic patients with pericardial effusion free of heart disease.

    abstract:STUDY OBJECTIVE:The purpose of this study was to evaluate the diagnostic value of low voltage with PR-segment and ST-T wave changes in determining the amount of clinically silent pericardial effusion detected in a routine echocardiography. DESIGN:Consecutive case series analysis. SETTING:Noninvasive cardiology depart...


    pub_type: 杂志文章


    authors: Kudo Y,Yamasaki F,Doi T,Doi Y,Sugiura T

    更新日期:2003-12-01 00:00:00

  • Prognostic value of bronchoalveolar lavage lymphocyte count in recently diagnosed pulmonary sarcoidosis.

    abstract::We prospectively looked at the prognostic value of bronchoalveolar lavage (BAL) lymphocyte count in 98 patients with recently diagnosed (less than 4 months) untreated sarcoidosis. These 50 men and 48 women (mean age, 37.4) were followed up for a period of 6 to 60 months (mean, 25.6), and were clinically evaluated ever...


    pub_type: 杂志文章


    authors: Laviolette M,La Forge J,Tennina S,Boulet LP

    更新日期:1991-08-01 00:00:00

  • Regulation of breathing and perception of dyspnea in healthy pregnant women.

    abstract:STUDY OBJECTIVE:To examine if the perception of dyspnea during normal pregnancy may be related to an inappropriate ventilatory response to the increased metabolic rate, due to a higher chemosensitivity. PATIENTS AND INTERVENTIONS:At weeks 12, 24, and 36 of gestation and 4 months after delivery, 11 healthy pregnant wom...


    pub_type: 杂志文章


    authors: García-Rio F,Pino JM,Gómez L,Alvarez-Sala R,Villasante C,Villamor J

    更新日期:1996-08-01 00:00:00

  • Antimicrobial therapy against Staphylococcus aureus, Pseudomonas aeruginosa, and Pseudomonas cepacia.

    abstract::The aims of antimicrobial therapy extend beyond short-term bacterial killing to long-term maintenance of weight and lung function. A review of antimicrobial drug trials shows that empiricism is still ahead of science and more studies are needed both to justify current practice and to make future changes logical. ...


    pub_type: 临床试验,杂志文章


    authors: Geddes DM

    更新日期:1988-08-01 00:00:00

  • Increased lung function decline in blue-collar workers exposed to welding fumes.

    abstract:BACKGROUND:There is no consensus at the present time about the effect of welding on lung function decline. This study compared lung function decline between blue-collar workers exposed and not exposed to welding fumes in a French longitudinal cohort of 21,238 subjects aged 37 to 52 years at inclusion. METHODS:Medical ...


    pub_type: 杂志文章


    authors: Thaon I,Demange V,Herin F,Touranchet A,Paris C

    更新日期:2012-07-01 00:00:00

  • Treatment of stage IIIA non-small cell lung cancer.

    abstract::Stage IIIA non-small cell lung cancer represents a relatively heterogeneous group of patients with metastatic disease to the ipsilateral mediastinal (N2) lymph nodes and also includes T3N1 patients. Presentations of disease range from apparently resectable tumors with occult microscopic nodal metastases to unresectabl...


    pub_type: 指南,杂志文章,实务指引,评审


    authors: Robinson LA,Wagner H Jr,Ruckdeschel JC,American College of Chest Physicians.

    更新日期:2003-01-01 00:00:00

  • Hemolysis in the aortic prosthetic valve.

    abstract::A review of the incidence and severity of hemolysis in the aortic prosthesis is presented. The noncloth-covered Starr-Edwards prosthetic series 1000, 1200, and 1260 had a 2 percent (1/54) incidence of anemia. The cloth-covered Starr-Edwards aortic prosthetic series 2300 was associated with anemia in 61 percent (28/46)...


    pub_type: 杂志文章


    authors: Santinga JT,Batsakis JT,Flora JD,Kirsh MM

    更新日期:1976-01-01 00:00:00

  • Pulmonary arterial wall distensibility assessed by intravascular ultrasound in children with congenital heart disease: an indicator for pulmonary vascular disease?

    abstract:BACKGROUND:Both pulmonary hypertension and pulmonary overflow are associated with functional and structural changes of the pulmonary arterial wall. Current techniques to evaluate the pulmonary vasculature neglect the pulsatile nature of pulmonary flow. STUDY OBJECTIVES:To determine whether the dynamic properties of th...


    pub_type: 杂志文章


    authors: Berger RM,Cromme-Dijkhuis AH,Hop WC,Kruit MN,Hess J

    更新日期:2002-08-01 00:00:00

  • Pulmonary vascular disease in secundum atrial septal defect with pulmonary hypertension.

    abstract::Histopathologic and morphometric studies of small pulmonary arteries were performed in 16 cases of secundum atrial septal defect (ASD) and severe pulmonary hypertension. Besides typical plexogenic arteriopathies found in six cases, organized microthrombi and what we call "musculoelastosis," that is, proliferation of l...


    pub_type: 杂志文章


    authors: Yamaki S,Horiuchi T,Miura M,Suzuki Y,Ishizawa E,Takahashi T

    更新日期:1986-05-01 00:00:00

  • Successful balloon aortic valvuloplasty in a patient with mitral valve endocarditis.

    abstract::A critically-ill 73-year-old man was admitted with simultaneous mitral valve endocarditis and aortic stenosis. Balloon aortic valvuloplasty was performed successfully and without complications and was followed by prompt clinical improvement. Balloon aortic valvuloplasty should be considered in patients with aortic ste...


    pub_type: 杂志文章


    authors: Burket MW

    更新日期:1991-06-01 00:00:00

  • Ultrafiltration in moderate heart failure. Exercise oxygen uptake as a predictor of the clinical benefits.

    abstract:OBJECTIVE:Ultrafiltration (UF) can improve the exercise performance of patients with moderate congestive heart failure (CHF). Our aim was to define the starting levels of performance below which UF is beneficial. PATIENTS AND METHOD:We studied 26 patients in 2 to 3 NYHA class, whose clinical condition was stable, left...


    pub_type: 杂志文章


    authors: Marenzi GC,Lauri G,Guazzi M,Perego GB,Agostoni PG

    更新日期:1995-07-01 00:00:00

  • Bronchoalveolar pepsin, bile acids, oxidation, and inflammation in children with gastroesophageal reflux disease.

    abstract:INTRODUCTION:Gastroesophageal reflux has been suggested as an underlying cause of chronic lung disease. The aim of this study was to assess the value of pepsin and bile acids, both components of GI secretions, in the lungs of children with chronic lung diseases as possible markers for gastroesophageal reflux disease an...


    pub_type: 杂志文章


    authors: Starosta V,Kitz R,Hartl D,Marcos V,Reinhardt D,Griese M

    更新日期:2007-11-01 00:00:00

  • Pott's disease. A resurgent challenge to the thoracic surgeon.

    abstract::Nineteen patients were treated at the Los Angeles County Harbor/UCLA Medical Center between 1971 and 1986 for tuberculosis of the spine. Fourteen were immigrants, a high-risk group. A high index of suspicion is required for Pott's disease, which occurs in fewer than 1 percent of patients with tuberculosis, often prese...


    pub_type: 杂志文章


    authors: Omari B,Robertson JM,Nelson RJ,Chiu LC

    更新日期:1989-01-01 00:00:00