Modulation of fibroblast activity in histiocytosis X by platelet-derived growth factor.

abstract：BACKGROUND:Pathogenic bacteria colonize the airways of 30% to 40% of patients with COPD and cause approximately 50% of exacerbations. New strains of nontypeable Haemophilus influenzae (NTHI) and Moraxella catarrhalis are associated with exacerbations. Antimicrobial protein/peptides (AMPs) play important roles in innate...

journal_title：Chest

authors： Parameswaran GI,Sethi S,Murphy TF

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Idiopathic pulmonary fibrosis (IPF) is a devastating disease, yet validated, reliable criteria for evaluating patient response to therapies in clinical trials are lacking. METHODS:To optimize selection of end point criteria for the study of interferon (IFN)-gamma1b in patients with IPF, we retrospectively a...

journal_title：Chest

authors： King TE Jr,Safrin S,Starko KM,Brown KK,Noble PW,Raghu G,Schwartz DA

更新日期：2005-01-01 00:00:00

abstract：:The alterations in metabolic (oxygen consumption [VO2] and carbon dioxide production [VCO2]) and hemodynamic (heart rate and blood pressure) parameters caused by various common intensive care activities were examined in a group of 23 mechanically-ventilated critically-ill patients. The observed variations in metabolic...

journal_title：Chest

authors： Weissman C,Kemper M,Damask MC,Askanazi J,Hyman AI,Kinney JM

更新日期：1984-12-01 00:00:00

abstract：BACKGROUND:The diagnostic yields with transbronchial needle aspiration (TBNA) for mediastinal nodes are highly variable. Nodal positions, as assessed on a breath-hold conventional CT scan, do not account for nodal motion. We studied nodal motion on four-dimensional (4D) CT scans. METHODS:A total of 47 mediastinal node...

journal_title：Chest

authors： Piet AH,Lagerwaard FJ,Kunst PW,van Sörnsen de Koste JR,Slotman BJ,Senan S

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND:Previous meta-analyses of pulmonary arterial hypertension (PAH)-specific therapy for PAH pooled PAH-specific combination therapy and monotherapy. This flaw may threaten the authenticity of their findings. METHODS:PubMed, Embase, and the Cochrane Library were searched for randomized controlled trials that ev...

journal_title：Chest

authors： Liu HL,Chen XY,Li JR,Su SW,Ding T,Shi CX,Jiang YF,Zhu ZN

更新日期：2016-08-01 00:00:00

abstract：:We present a case of successfully resected alpha-fetoprotein (AFP)-producing primary lung cancer. AFP in the serum decreased from 289 ng/ml to an undetectable level after a curative operation. The resected tumor was stained positively by the immunohistochemical study for AFP. The histologic appearance of the tumor was...

journal_title：Chest

authors： Saka H,Sakai S,Kondo N,Ito M,Shimokata K

更新日期：1988-10-01 00:00:00

abstract：:Medical malpractice with its associated costs, including insurance premiums, impact on practice, consequences for career and insurability, and emotional toll, is a reality of practicing medicine in the United States. Understanding the types of claims that may be asserted, the issues to consider when securing insurance...

journal_title：Chest

authors： Nepps ME

更新日期：2008-11-01 00:00:00

abstract：:Recent studies have suggested that vasodilators may acutely improve pulmonary hemodynamics in patients with chronic obstructive pulmonary disease and cor pulmonale, but the effects of long-term therapy have not been assessed. We evaluated the hemodynamic and gas exchange effects of nitrendipine, a calcium channel bloc...

journal_title：Chest

authors： Rubin LJ,Moser K

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND:Endobronchial ultrasound (EBUS)-guided transbronchial needle aspiration (EBUS-TBNA) is performed with a dedicated 22- or 21-gauge needle while suction is applied. Fine-needle sampling without suction (capillary sampling) has been studied for endoscopic ultrasound and for biopsies at various body sites and ha...

journal_title：Chest

authors： Casal RF,Staerkel GA,Ost D,Almeida FA,Uzbeck MH,Eapen GA,Jimenez CA,Nogueras-Gonzalez GM,Sarkiss M,Morice RC

更新日期：2012-09-01 00:00:00

abstract：STUDY OBJECTIVES:The purpose of this 12-week study was to evaluate the efficacy and safety of adjunct modafinil to treat excessive sleepiness in patients with obstructive sleep apnea (OSA) who experience residual sleepiness despite regular nasal continuous positive airway pressure (nCPAP) use. DESIGN:Twelve-week, open...

journal_title：Chest

authors： Schwartz JR,Hirshkowitz M,Erman MK,Schmidt-Nowara W

更新日期：2003-12-01 00:00:00

abstract：:The work of chest inflation, WI, is a primary determinant of the need for ventilatory support and an integrative index of elastic and resistive impedance. Although the mechanical work performed by a ventilator in moving gas into the passive chest (WI = integral of PV dt) can be determined by measuring the area enclose...

journal_title：Chest

authors： Marini JJ,Rodriguez RM,Lamb V

更新日期：1986-01-01 00:00:00

abstract：UNLABELLED:STUDY PURPOSES: To survey hospital laboratories in the United States to determine methods used for measuring pleural fluid pH, and to compare pleural fluid pH values obtained with a traditional tabletop blood gas analyzer (BGA) to those obtained with a handheld analyzer. METHODS:Hospital laboratories nation...

journal_title：Chest

authors： Kohn GL,Hardie WD

更新日期：2000-12-01 00:00:00

abstract：BACKGROUND:Obesity hypoventilation syndrome (OHS) conventionally includes awake hypercapnia, but an isolated raised bicarbonate, even in the absence of awake hypercapnia, may represent evidence of "early" OHS. We investigated whether such individuals exhibit certain features characteristic of established OHS. METHODS:...

journal_title：Chest

authors： Manuel ARG,Hart N,Stradling JR

更新日期：2015-02-01 00:00:00

abstract：:Previous work has shown that with increasing airway obstruction in chronic obstructive pulmonary disease, the decrement in the maximum midexpiratory flow (MMEF) is exponential. Therefore, with severe obstructive disease the decrease in the MMEF as the disease progresses is difficult to discern. This work points out th...

journal_title：Chest

authors： Sobol BJ,Emirgil C

更新日期：1977-07-01 00:00:00

abstract：:A recent study on stable, hypoxemic, COLD patients in which ANP was stimulated by LBPP demonstrated that in these individuals elevation of ANP does not exert a "normal" suppressing effect on the PRA-PA axis. Accordingly, we exercised ten comparable COLD patients, another maneuver known to stimulate ANP and to elicit c...

journal_title：Chest

authors： Mannix ET,Manfredi F,Palange P,Aronoff GR,Weinberger MH,Farber MO

更新日期：1992-02-01 00:00:00

abstract：STUDY OBJECTIVES:To determine if Asian immigrants to the United States present with more advanced lung cancer compared to non-Asians. DESIGN:A 5-year retrospective case-control study (January 1, 1992, to December 31, 1996) of patients with lung cancer identified using the New England Medical Center cancer center datab...

journal_title：Chest

authors： Finlay GA,Joseph B,Rodrigues CR,Griffith J,White AC

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:There are several reports on underdiagnosis of COPD, while little is known about COPD overdiagnosis and overtreatment. We describe the overdiagnosis and the prevalence of spirometrically defined false positive COPD, as well as their relationship with overtreatment across 23 population samples in 20 countries...

journal_title：Chest

authors： Sator L,Horner A,Studnicka M,Lamprecht B,Kaiser B,McBurnie MA,Buist AS,Gnatiuc L,Mannino DM,Janson C,Bateman ED,Burney P,BOLD Collaborative Research Group.

更新日期：2019-08-01 00:00:00

abstract：:We characterized the bronchopulmonary distribution of a 0.9 percent saline aerosol (1.12 microM) labelled with 99mTc sulfur colloid in nine normal subjects and five patients with CF. Homogeneity of distribution was quantified using indices derived from computerized analysis of Anger camera pulmonary images including s...

journal_title：Chest

authors： Laube BL,Links JM,LaFrance ND,Wagner HN Jr,Rosenstein BJ

更新日期：1989-04-01 00:00:00

abstract：STUDY OBJECTIVES:Inspiratory capacity (IC) has been proposed as a simple method to assess acute changes in functional residual capacity (FRC) with bronchodilation, assuming that total lung capacity (TLC) is unchanged. This assumption is based on studies using body plethysmography, which may not accurately measure TLC i...

journal_title：Chest

authors： Duranti R,Filippelli M,Bianchi R,Romagnoli I,Pellegrino R,Brusasco V,Scano G

更新日期：2002-12-01 00:00:00

abstract：STUDY OBJECTIVE:Data on the prevalence of myocarditis in children are limited. Autopsy studies have shown that myocarditis is often undiagnosed. We attempted to investigate the clinical features of asymptomatic myocarditis in four schoolchildren detected during a mass ECG screening in schoolchildren. DESIGN AND SETTIN...

journal_title：Chest

authors： Nakagawa M,Sato A,Okagawa H,Kondo M,Okuno M,Takamatsu T

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND:We investigated whether artificial neural networks (ANNs) could diagnose pathology of lymph nodes by feeding B-mode images from convex-type echobronchoscopy to ANNs. METHODS:Subjects comprised 91 patients who had undergone endobronchial ultrasonography transbronchial needle aspiration at our hospital betwee...

journal_title：Chest

authors： Tagaya R,Kurimoto N,Osada H,Kobayashi A

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVES:Clinical practice guidelines have been devised to change practitioner performance and to improve the process and outcomes of care. The objective of this study was to determine whether adherence to a practice guideline on noninvasive positive-pressure ventilation (NPPV) for the treatment of patients with acut...

journal_title：Chest

authors： Sinuff T,Cook DJ,Randall J,Allen CJ

更新日期：2003-06-01 00:00:00

abstract：:Breathing against positive expiratory pressure has been used to improve gas exchange in many forms of pulmonary edema, and forced expiration against resistance during exercise has been advocated for climbing at high altitude as a method to optimize performance. To evaluate the effect of expiratory positive airway pres...

journal_title：Chest

authors： Schoene RB,Roach RC,Hackett PH,Harrison G,Mills WJ Jr

更新日期：1985-03-01 00:00:00

abstract：:Of 354 thoracotomies, 114 cases involved intraoperative cytopathologic evaluation. The study included 86 men and 28 women, and 184 specimens were examined. Smears were taken from the lung lesion or lymph node and the chest wall or bronchial stump by imprint or needle aspiration. Intraoperative evaluations were compare...

journal_title：Chest

authors： Terada Y,Matsunobe S,Nemoto T,Tsuda T,Shimizu Y

更新日期：1990-11-01 00:00:00

abstract：:The narcotic antagonists naloxone and naltrexone were used as respiratory stimulants in two patients failing traditional medical therapy for COPD. Both patients demonstrated improvement while receiving the drugs, but developed respiratory failure when they were discontinued abruptly. In selected patients with COPD, na...

journal_title：Chest

authors： Reents SB,Beck CA Jr

更新日期：1988-01-01 00:00:00

abstract：:An unruptured aneurysm of the left sinus of Valsalva was diagnosed by angiography in a 16-year-old male subject 19 years ago. A recent repeated angiographic study documented no change in the aneurysm over the 19-year interval, and the patient has remained asymptomatic. We are aware of no other long-term follow-up repo...

journal_title：Chest

authors： Martin LW,Hsu I,Schwartz H,Wasserman AG

更新日期：1986-07-01 00:00:00

abstract：:Expired gas and gas leaked via thoracostomy tubes was collected in nine patients with the adult respiratory distress syndrome (ARDS) and bronchopleural fistulas. Mean minute ventilation in the group was 23.9 +/- 7.5 L/min with 31 +/- 23 percent of the gas escaping via the leak. Carbon dioxide was present in the leaked...

journal_title：Chest

authors： Bishop MJ,Benson MS,Pierson DJ

更新日期：1987-03-01 00:00:00

abstract：:Clotting abnormalities are well-recognized complications that occur with high frequency in patients suffering from underlying malignant diseases. New and highly sensitive molecular markers of hemostasis, thrombin-antithrombin III complex (TAT III), D-dimer fragments (DD), and plasmin-alpha 2-antiplasmin complex (PIC) ...

journal_title：Chest

authors： Gabazza EC,Taguchi O,Yamakami T,Machishi M,Ibata H,Suzuki S

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Little information is available about the prevalence of deep vein thrombosis (DVT) after discharge from cardiac surgery units and its impact on rehabilitation programs. OBJECTIVES:To estimate the rate of DVT, in relation to different thromboprophylaxis strategies, in patients with a recent coronary artery b...

journal_title：Chest

authors： Ambrosetti M,Salerno M,Zambelli M,Mastropasqua F,Tramarin R,Pedretti RF

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVE:We hypothesized that intermittent hypoxia might influence serum substance P levels, and that this effect might in turn contribute in excessive daytime sleepiness (EDS) in patients with obstructive sleep apnea syndrome (OSAS). PATIENTS AND METHODS:Fifty-five patients with newly diagnosed OSAS and 15 age-match...

journal_title：Chest

authors： Ursavas A,Karadag M,Ilcol YO,Burgazlioglu B,Ercan I,Gozu RO

更新日期：2007-05-01 00:00:00