Abstract:
:We present a case of successfully resected alpha-fetoprotein (AFP)-producing primary lung cancer. AFP in the serum decreased from 289 ng/ml to an undetectable level after a curative operation. The resected tumor was stained positively by the immunohistochemical study for AFP. The histologic appearance of the tumor was well-differentiated adenocarcinoma similar to that of fetal gut epithelium and apparently different from extragonadal germ cell tumor. This case provides evidence that lung cancer cells possess the potential to produce AFP.
journal_name
Chestjournal_title
Chestauthors
Saka H,Sakai S,Kondo N,Ito M,Shimokata Kdoi
10.1378/chest.94.4.879subject
Has Abstractpub_date
1988-10-01 00:00:00pages
879-80issue
4eissn
0012-3692issn
1931-3543pii
S0012-3692(16)30604-3journal_volume
94pub_type
杂志文章相关文献
CHEST文献大全abstract:BACKGROUND:In addition to affecting the oxygen supply to the brain, pulmonary function is a marker of multiple insults throughout life (including smoking, illness, and socioeconomic deprivation). In this meta-analysis of existing longitudinal studies, the hypothesis that lower pulmonary function and respiratory illness...
journal_title:Chest
pub_type: 杂志文章
doi:10.1016/j.chest.2019.12.012
更新日期:2020-06-01 00:00:00
abstract::Targeted temperature management (TTM) has been investigated experimentally and used clinically for over 100 years. The initial rationale for the clinical application of TTM, historically referred to as therapeutic hypothermia, was to decrease the metabolic rate, allowing the injured brain time to heal. Subsequent rese...
journal_title:Chest
pub_type: 历史文章,杂志文章,评审
doi:10.1378/chest.12-3025
更新日期:2014-02-01 00:00:00
abstract:BACKGROUND:It is unclear whether an abnormal swallowing reflex affects COPD exacerbations. This study investigated the prevalence of abnormal swallowing reflexes and its relationship with COPD exacerbation prospectively. We also clarified its association with gastroesophageal reflux disease (GERD) and airway bacterial ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.09-0482
更新日期:2010-02-01 00:00:00
abstract::Flexible bronchoscopy (FB) is uniquely suited for the study of large airway lesions in the ventilated premature infant. However, no standardized clinical scoring system of distal tracheal injury exists and the adverse consequences of FB in ventilated premature infants are not well described. Using a prototype Olympus ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.98.5.1219
更新日期:1990-11-01 00:00:00
abstract:STUDY OBJECTIVE:To evaluate the cost effectiveness of the Nd-YAG laser and bronchoscopic electrocautery for palliation in patients with symptomatic tumor obstruction. DESIGN:A retrospective study. SETTING:Bronchoscopy unit of a university hospital. PATIENTS AND INTERVENTION:Thirty-one consecutive patients with inope...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.116.4.1108
更新日期:1999-10-01 00:00:00
abstract::In the past decade and a half, the introduction of new therapeutic agents has revolutionized the management of pulmonary arterial hypertension (PAH). These new treatment options have improved the quality of life and survival in PAH. With an armamentarium of options available, the identification of unique phenotypes ca...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1016/j.chest.2017.08.1159
更新日期:2018-02-01 00:00:00
abstract:BACKGROUND:The practice of treating a solitary pulmonary nodule (SPN) suspicious for stage I non-small cell lung cancer (NSCLC) with stereotactic ablative radiotherapy (SABR) in the absence of pathology is growing. In the absence of randomized evidence, the appropriate prior probability threshold of lung cancer of when...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.13-2924
更新日期:2014-10-01 00:00:00
abstract:BACKGROUND:In a rodent model of cardiac arrest and resuscitation in which the inspired gas mixture was enriched with oxygen, resuscitability and survival were unaffected by positive pressure ventilation. In the present study, in a larger animal model, tidal volumes generated during precordial compression and with spont...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.108.3.821
更新日期:1995-09-01 00:00:00
abstract:STUDY OBJECTIVE:To determine how the volume and severity of emphysema measured by CT morphometry (CTM) before and after lung volume reduction surgery (LVRS) relates to the functional status of patients after LVRS. DESIGN:A histologically validated CT algorithm was used to quantify the volume and severity of emphysema ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.118.5.1240
更新日期:2000-11-01 00:00:00
abstract::We report 4 cases of Churg-Strauss syndrome (CSS) that occurred in patients being treated with corticosteroids for a diagnosis of asthma. One patient had asthma, eosinophilia, and eosinophilic lymphadenopathy that regressed with higher doses of corticosteroids. The second patient had both eosinophilic tissue infiltrat...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.108.2.320
更新日期:1995-08-01 00:00:00
abstract::Activated charcoal usually provides effective and safe treatment for drug overdose. We describe a patient who developed bronchiolitis obliterans and respiratory failure following aspiration of activated charcoal. This patient had a markedly reduced vital capacity with roentgenographic evidence of airtrapping. Chest ro...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.96.3.672
更新日期:1989-09-01 00:00:00
abstract:INTRODUCTION:CXC chemokine receptor 1 (CXCR1) and CXC chemokine receptor 2 (CXCR2) have been shown to play an important role in transepithelial migration of neutrophil granulocytes during inflammation in various tissues. This study investigated the regulation of gene expression and surface expression of CXCR1 and CXCR2...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.128.5.3724
更新日期:2005-11-01 00:00:00
abstract:BACKGROUND:COPD and hypertension both increase the risk of congestive heart failure (CHF). Current clinical trials do not inform the selection of combination antihypertensive therapy among patients with COPD. We performed a comparative effectiveness study to investigate whether choice of dual agent antihypertensive the...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.12-1770
更新日期:2013-05-01 00:00:00
abstract::Pancreaticopleural fistula secondary to chronic pancreatitis is a rare cause of recurrent pleural effusion. The demonstration of the fistula with endoscopic retrograde pancreatography and CT is invasive or limited. We report in two patients the use of magnetic resonance pancreatography as a noninvasive alternative to ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.117.3.912
更新日期:2000-03-01 00:00:00
abstract:BACKGROUND:Increased expression of the human epididymis protein 4 (HE4) was previously described in lung biopsy samples from patients with cystic fibrosis (CF). It remains unknown, however, whether serum HE4 concentrations are elevated in CF. METHODS:Seventy-seven children with CF from six Hungarian CF centers and 57 ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1016/j.chest.2016.04.006
更新日期:2016-09-01 00:00:00
abstract::The influence of positive expiratory pressure (PEP) applied during inhalation of a beta 2-agonist in treatment of bronchial asthma was investigated in a randomized crossover study with two-week treatment periods. In one period, two puffs (0.5 mg) of terbutaline was given from a metered dose inhaler and inhaled through...
journal_title:Chest
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1378/chest.100.2.317
更新日期:1991-08-01 00:00:00
abstract::A mechanical model was employed to examine phase and amplitude relationships between simulated pleural and mouth pressures during panting at different frequencies with and without lower airway obstruction and with rigid or flaccid extrathoracic airways. Results confirm the hypothesis that, in the presence of lower air...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.86.4.589
更新日期:1984-10-01 00:00:00
abstract:OBJECTIVE:To highlight the incidence of subglottic stenosis (SGS) as a complication of surgery for congenital heart disease and the role of single-stage laryngotracheoplasty in treating this complication. DESIGN:Retrospective case series. SETTING:University-based referral center specializing in surgery for congenital...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.111.6.1769
更新日期:1997-06-01 00:00:00
abstract::Comprehensive pulmonary rehabilitation and respiratory therapy services benefit patients with chronic lung disease and other diseases of the lung by reducing symptoms and restoring independent function. Although the science of these therapies is not new, commercial payers and Medicare have generally been slow to suppo...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1378/chest.10-2392
更新日期:2011-06-01 00:00:00
abstract::A post-right pneumonectomy syndrome is described which manifests symptoms of exertional dyspnea and inspiratory stridor on rapid inspiration. These symptoms were associated with marked rightward and posterior deviation of the trachea, over-distention of the left lung with its herniation into the right side of the ches...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.75.1.78
更新日期:1979-01-01 00:00:00
abstract::A review of the largest observational studies on post-ICU weaning from prolonged mechanical ventilation yields evidence that more than half of such patients can be successfully liberated from mechanical ventilation. Success is likely to fall within a 3-month window, with late successes and partial ventilator independe...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1378/chest.120.6_suppl.482s
更新日期:2001-12-01 00:00:00
abstract::False-negative supine M-mode echocardiograms occur in some patients with proved mitral valve prolapse. To investigate further, we performed M-mode echocardiography (MME) during standing and after the inhalation of amyl nitrite in 17 patients (group 1) selected for auscultatory evidence of mitral valve prolapse (MVP) b...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.82.2.158
更新日期:1982-08-01 00:00:00
abstract::An unusual case of arteriovenous communication between the left inferior epigastric artery, a branch of the femoral artery, and the superior vena cava is presented. The communication caused a continuous murmur at the lower parasternal area and was responsible for a significant left-to-right shunt. Surgical treatment, ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.74.2.226
更新日期:1978-08-01 00:00:00
abstract::Prior to 1978, the conventional treatment of pneumothorax generally consisted of conservative therapies such as rest, needle puncture, or thoracic cavity drainage; however, when conservative therapies were ineffective or relapse occurred therapeutic approach, 34 percent (11/32) of our patients required a thoracotomy. ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.100.4.953
更新日期:1991-10-01 00:00:00
abstract::A total of 161 patients with chronic obstructive pulmonary disease (COPD) plus 100 control subjects (identified during a study of heart disease in 6,860 Japanese-American men aged 52 to 75 years who were residing in Hawaii) were analyzed for phenotype in search of the antitrypsin gene Z, which has been shown to be ass...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.72.4.489
更新日期:1977-10-01 00:00:00
abstract::In order to identify correlates of fibrosis in acute respiratory failure, autopsies were performed on 16 patients who died after an episode of more than two weeks' duration, and the left lower lung lobe was obtained for biochemical measurements. The average amount of lobar collagen in one group of patients was nearly ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.85.5.641
更新日期:1984-05-01 00:00:00
abstract::Spontaneous echo contrast is uncommon in pericardial effusion. We report the case of a patient with massive malignant pericardial effusion causing cardiac tamponade in which the intense spontaneous echo contrast was found in the effusion by echocardiography. It was suggested that both the heavy blood content and a lar...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.103.5.1600
更新日期:1993-05-01 00:00:00
abstract::A patient had left ventricular pseudoaneurysm after mitral valve replacement surgery. The diagnosis was made by color flow Doppler demonstration of systolic flow between the left ventricular chamber and an echo-free space posterior to the heart which was initially interpreted as localized pleural effusion. Color Doppl...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.95.1.231
更新日期:1989-01-01 00:00:00
abstract::Marked airway obstruction and interference with gas exchange was encountered following institution of general anesthesia for resection of a cystic subcarinal mass. Intraoperative bronchoscopy revealed marked airway compression. The cyst was decompressed using a transbronchial needle through a fiberbronchoscope. This a...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.97.6.1490
更新日期:1990-06-01 00:00:00
abstract::A 25-year-old man was treated with gastric lavage and activated charcoal for alcohol and drug overdose; immediately following the initial treatment he developed tension pneumothorax successfully managed with a chest tube. The patient presented four weeks later with a charcoal-containing empyema, an unreported conditio...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.87.3.404
更新日期:1985-03-01 00:00:00