Successful resection of alpha-fetoprotein-producing lung cancer.


:We present a case of successfully resected alpha-fetoprotein (AFP)-producing primary lung cancer. AFP in the serum decreased from 289 ng/ml to an undetectable level after a curative operation. The resected tumor was stained positively by the immunohistochemical study for AFP. The histologic appearance of the tumor was well-differentiated adenocarcinoma similar to that of fetal gut epithelium and apparently different from extragonadal germ cell tumor. This case provides evidence that lung cancer cells possess the potential to produce AFP.






Saka H,Sakai S,Kondo N,Ito M,Shimokata K




Has Abstract


1988-10-01 00:00:00
















  • The effect of montelukast and low-dose theophylline on cardiovascular disease risk factors in asthmatics.

    abstract:BACKGROUND:Recent studies have implicated the 5-lipoxygenase/leukotriene (LT) pathway in cardiovascular disease (CVD), which may have important implications for asthmatics because several drugs that target this pathway are currently used to treat asthma. We sought to determine whether montelukast, a cysteinyl LT antago...


    pub_type: 杂志文章,随机对照试验


    authors: Allayee H,Hartiala J,Lee W,Mehrabian M,Irvin CG,Conti DV,Lima JJ

    更新日期:2007-09-01 00:00:00

  • Spontaneous middle lobe torsion secondary to pleural effusion.

    abstract::Pulmonary torsion is very rare, and usually occurs following lung resection. We report a case of spontaneous middle lobe torsion in a patient presenting with a right pleural effusion. The condition was treated by lobectomy through a totally thoracoscopic approach. ...


    pub_type: 杂志文章


    authors: Raynaud C,Lenoir S,Caliandro R,Raffenne L,Validire P,Gossot D

    更新日期:2009-07-01 00:00:00

  • Left lung asthma.

    abstract::The chest radiograph of a woman with acute asthma showed signs of obstructive emphysema of the left lung. Fiberoptic bronchoscopy excluded obstruction of a large bronchus. The signs disappeared after antiasthmatic treatment, suggesting that they were caused by airway closure. In usual asthma, airway closure affects bo...


    pub_type: 杂志文章


    authors: DiFrancia M,Barbier D,Orehek J

    更新日期:1993-12-01 00:00:00

  • Atrial function during cardiac arrest caused by ventricular fibrillation.

    abstract:OBJECTIVES:To report observations on preserved regular atrial electrical and mechanical systole during ventricular fibrillation (VF) and to quantitate blood flow generated by atrial contractions in this setting. METHODS:In 10 rats, right atrial pressure pulses were continuously recorded before and for an interval of 8...


    pub_type: 杂志文章


    authors: Pernat A,Weil MH,Sun S,Tang W,Yamaguchi H,Bisera J

    更新日期:2000-04-01 00:00:00

  • Thrombosed prosthetic valve in tricuspid position. Successful therapy with intravenous streptokinase.

    abstract::The successful use of streptokinase therapy in a child with chronic thrombosis of a prosthetic valve (Carbomedics) in the tricuspid position is presented. ...


    pub_type: 杂志文章


    authors: Mehan VK,Dalvi BV,Kale PA

    更新日期:1992-11-01 00:00:00

  • Cerebrospinal fluid leak and meningitis associated with nasal continuous positive airway pressure therapy.

    abstract::Clear rhinorrhea is a common symptom in patients with obstructive sleep apnea (OSA) and may worsen with continuous positive airway pressure therapy. Clear rhinorrhea can also be the presenting symptom of cerebrospinal fluid (CSF) leak, which is evidence of a communication between the subarachnoid space and the nasal c...


    pub_type: 杂志文章


    authors: Kuzniar TJ,Gruber B,Mutlu GM

    更新日期:2005-09-01 00:00:00

  • Pancreaticopleural fistula: diagnosis with magnetic resonance pancreatography.

    abstract::Pancreaticopleural fistula secondary to chronic pancreatitis is a rare cause of recurrent pleural effusion. The demonstration of the fistula with endoscopic retrograde pancreatography and CT is invasive or limited. We report in two patients the use of magnetic resonance pancreatography as a noninvasive alternative to ...


    pub_type: 杂志文章


    authors: Materne R,Vranckx P,Pauls C,Coche EE,Deprez P,Van Beers BE

    更新日期:2000-03-01 00:00:00

  • Nocturnal oxygen desaturation correlates with the severity of coronary atherosclerosis in coronary artery disease.

    abstract:STUDY OBJECTIVES:It has been suggested that sleep-disordered breathing (SDB) is a risk factor for ischemic heart disease, and may be associated with increased morbidity and mortality due to cardiovascular disease. The aim of this study was to examine the relation between nocturnal oxygen desaturation (NOD) due to SDB a...


    pub_type: 杂志文章


    authors: Hayashi M,Fujimoto K,Urushibata K,Uchikawa S,Imamura H,Kubo K

    更新日期:2003-09-01 00:00:00

  • Clinical factors associated with persistent pericardial effusion after successful primary coronary angioplasty.

    abstract:STUDY OBJECTIVE:To evaluate the incidence and clinical factors related to the persistence of infarct-associated pericardial effusion (PE) after primary angioplasty. DESIGN:Consecutive case-series analysis. SETTING:Coronary care unit in a university hospital. PATIENTS:Three hundred ninety-one consecutive patients wit...


    pub_type: 杂志文章


    authors: Sugiura T,Nakamura S,Kudo Y,Okumiya T,Yamasaki F,Iwasaka T

    更新日期:2005-08-01 00:00:00

  • Cerebral vascular responsiveness in chronic hypercapnia.

    abstract::To assess the responsiveness of the cerebral vessels to chronic hypercapnia, we measured middle cerebral artery flow velocity by transcranial Doppler ultrasound in 20 normal subjects and in 14 COLD patients before and after stimulation by progressive hypercapnia (rebreathing test) or by intravenous administration of a...


    pub_type: 杂志文章


    authors: Clivati A,Ciofetti M,Cavestri R,Longhini E

    更新日期:1992-07-01 00:00:00

  • A Case of Lymphangiomatosis With Infected Lymphangiomas Effectively Treated by Thoracoscopic Debridement and Drainage.

    abstract::A 40-year-old woman with lymphangiomatosis also had an intrathoracic lymphangioma infection. Since the age of 8 years, the patient had undergone repeated abdominal and mediastinal cyst surgeries and had received a diagnosis of lymphangiomatosis. At this time, she showed a high fever of 38.5°C. Cultures of both blood a...




    authors: Minakata T,Suzuki T,Kamio Y,Kadokura M,Himuro N,Takei H

    更新日期:2020-11-01 00:00:00

  • Interobserver Reliability of the Berlin ARDS Definition and Strategies to Improve the Reliability of ARDS Diagnosis.

    abstract:BACKGROUND:Failure to reliably diagnose ARDS may be a major driver of negative clinical trials and underrecognition and treatment in clinical practice. We sought to examine the interobserver reliability of the Berlin ARDS definition and examine strategies for improving the reliability of ARDS diagnosis. METHODS:Two hu...


    pub_type: 杂志文章


    authors: Sjoding MW,Hofer TP,Co I,Courey A,Cooke CR,Iwashyna TJ

    更新日期:2018-02-01 00:00:00

  • Effects on the renin-angiotensin system of agents acting at central and peripheral adrenergic receptors.

    abstract::Although the principal actions of clonidine are linked to its centrally mediated suppression of sympathetic activity, its inhibition of the renin axis also may contribute to its antihypertensive effects. In patients with essential hypertension studied in a clinical research center, clonidine-induced decreases in diast...


    pub_type: 杂志文章


    authors: Weber MA,Drayer JI,Hubbell FA

    更新日期:1983-02-01 00:00:00

  • Pulmonary function and abdominal adiposity in the general population.

    abstract:BACKGROUND:The prevalence of obesity is increasing, and there is evidence that obesity, in particular abdominal obesity as a marker of insulin resistance, is negatively associated with pulmonary function. The mechanism for this association and the best marker of abdominal adiposity in relation to pulmonary function is ...


    pub_type: 杂志文章


    authors: Ochs-Balcom HM,Grant BJ,Muti P,Sempos CT,Freudenheim JL,Trevisan M,Cassano PA,Iacoviello L,Schünemann HJ

    更新日期:2006-04-01 00:00:00

  • Accuracy of an infrared tympanic thermometer.

    abstract:BACKGROUND:The use of infrared thermometry to measure temperatures in hospitalized patients is increasing. Although infrared thermometers have been proven to be accurate when they are used by well-trained personnel, no previous studies have examined their accuracy during routine hospital use. OBJECTIVE:To determine th...


    pub_type: 杂志文章


    authors: Amoateng-Adjepong Y,Del Mundo J,Manthous CA

    更新日期:1999-04-01 00:00:00

  • Epidemiology and clinicopathology of aortic dissection.

    abstract:STUDY OBJECTIVES:To determine the incidence and mortality as well as to analyze the clinical and pathologic changes of aortic dissection. DESIGN AND SETTING:A population-based longitudinal study over 27 years on a study population of 106,500, including 66 hospitalized and 18 nonhospitalized consecutively observed pati...


    pub_type: 杂志文章


    authors: Mészáros I,Mórocz J,Szlávi J,Schmidt J,Tornóci L,Nagy L,Szép L

    更新日期:2000-05-01 00:00:00

  • The Master Settlement Agreement and its impact on tobacco use 10 years later: lessons for physicians about health policy making.

    abstract::The issue of tobacco industry responsibility for population health problems and compensation for their treatment has been growing since the 1960s. In 1999, the state attorneys general collectively launched the largest class action lawsuit in US history and sued the tobacco industry to recover the costs of caring for s...


    pub_type: 杂志文章,评审


    authors: Jones WJ,Silvestri GA

    更新日期:2010-03-01 00:00:00

  • Diagnosis of causes for acute respiratory distress by pressure-volume curves.

    abstract::The determination of effective dynamic and static relationships between pressure and volume aided in the diagnosis of pulmonary disease, its course, and the effects of therapy in 22 patients receiving continuous mechanical ventilation. These measurements were made on multiple occasions early in the course of mechanica...


    pub_type: 杂志文章


    authors: Bone RC

    更新日期:1976-12-01 00:00:00

  • Endobronchial ultrasound-guided transbronchial needle aspiration of lymph nodes in the radiologically and positron emission tomography-normal mediastinum in patients with lung cancer.

    abstract::Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) can reliably sample enlarged mediastinal lymph nodes in patients with non-small cell lung cancer (NSCLC), and in practice is mostly used to sample nodes visible on CT or positron emission tomography (PET). Few data are available on the use of...


    pub_type: 临床试验,杂志文章


    authors: Herth FJ,Eberhardt R,Krasnik M,Ernst A

    更新日期:2008-04-01 00:00:00

  • Methylated Genes in Sputum Among Older Smokers With Asthma.

    abstract:OBJECTIVE:The epigenetic basis for human asthma is not well studied, particularly among older adults. This study investigated the methylation profiles in sputum DNA among older adults with asthma, using a population of smokers. METHODS:This was a cross-sectional study using the Lovelace Smokers Cohort, a population of...


    pub_type: 杂志文章


    authors: Sood A,Petersen H,Blanchette CM,Meek P,Picchi MA,Belinsky SA,Tesfaigzi Y

    更新日期:2012-08-01 00:00:00

  • Transforming growth factor-beta 1 and extracellular matrix-associated fibronectin expression in pulmonary lymphangioleiomyomatosis.

    abstract:STUDY OBJECTIVES:Lymphangioleiomyomatosis (LAM) is a rare disorder of unknown etiology, affecting almost exclusively women of childbearing age, that is associated with the proliferation of spindle cells and cystic changes in the affected lung. The underlying processes that contribute to this disease are poorly understo...


    pub_type: 杂志文章


    authors: Evans SE,Colby TV,Ryu JH,Limper AH

    更新日期:2004-03-01 00:00:00

  • Massive hemoptysis during catheterization of the internal jugular vein.

    abstract::Percutaneous cannulation of the internal jugular vein is commonly performed to obtain central venous access. We report the first case of massive hemoptysis occurring during cannulation of the internal jugular vein. ...


    pub_type: 杂志文章


    authors: Friedman Y,Tilly E,Rackow EC,Weil MH

    更新日期:1989-05-01 00:00:00

  • Poor symptom control is associated with reduced CT scan segmental airway lumen area in smokers with asthma.

    abstract:BACKGROUND:Cigarette smoking is associated with worse symptoms in asthma and abnormal segmental airways in healthy subjects. We tested the hypothesis that current symptom control in smokers with asthma is associated with altered segmental airway dimensions measured by CT scan. METHODS:In 93 subjects with mild, moderat...


    pub_type: 杂志文章


    authors: Thomson NC,Chaudhuri R,Spears M,Messow CM,MacNee W,Connell M,Murchison JT,Sproule M,McSharry C

    更新日期:2015-03-01 00:00:00

  • Pulmonary hypertension in chronic obstructive pulmonary disease. Multivariate analysis.

    abstract::The severity of pulmonary hypertension was evaluated by right cardiac catheterization in 89 patients with stable chronic obstructive pulmonary disease, both at rest and during maximum treadmill exercise. Thirty-one patients were found to have pulmonary hypertension at rest, defined as a mean pulmonary arterial pressur...


    pub_type: 杂志文章


    authors: Keller CA,Shepard JW Jr,Chun DS,Vasquez P,Dolan GF

    更新日期:1986-08-01 00:00:00

  • The controversy of combination vs monotherapy in the treatment of hospitalized community-acquired pneumonia.

    abstract:BACKGROUND:The majority of community-acquired pneumonia (CAP) patients (about 80%) will be treated as outpatients, because therapy with a single agent will work. For the remaining 20% of patients requiring hospitalization, there is some growing debate regarding the efficacy of different management approaches. For hospi...


    pub_type: 杂志文章,评审


    authors: Weiss K,Tillotson GS

    更新日期:2005-08-01 00:00:00

  • Continuous positive airway pressure and supplemental oxygen in the treatment of cardiogenic pulmonary edema.

    abstract::The efficacy of continuous positive airway pressure (CPAP) administered with a face mask was compared to oxygen supplementation in 40 patients with acute cardiogenic pulmonary edema. Baseline arterial blood gas values and pH, heart rate, respiratory rate, and blood pressure were recorded after patients breathed 28 per...


    pub_type: 杂志文章


    authors: Väisänen IT,Räsänen J

    更新日期:1987-09-01 00:00:00

  • Mediastinal lymph node enlargement as a result of mitral valve stenosis.

    abstract::Two patients are described with severe MVS, pulmonary venous hypertension and enlarged mediastinal, pulmonary and hilar lymph nodes. These enlargements were diagnosed on a preoperative chest CT. After MV replacement these enlarged lymph nodes nearly all resolved. The lymphadenopathy should be considered to be secondar...


    pub_type: 杂志文章


    authors: Drent M,Gelissen JP,Ascoop CA,Wagenaar SS,van den Bosch JM

    更新日期:1992-10-01 00:00:00

  • Cardiopulmonary support mitigates the effects of experimental myocardial ischemia.

    abstract::The effectiveness of cardiopulmonary support (CPS) as a rescue method following failed angioplasty is unknown. The proximal left anterior descending (LAD) was occluded for 20 min in 21 dogs. Group 1 animals (n=15) were given CPS and group 2 animals (n=6) served as controls. During coronary occlusion, animals receiving...


    pub_type: 杂志文章


    authors: Ward HB,McFalls EO,Baldwin D,Nemzek TG,Gornick CC

    更新日期:1996-03-01 00:00:00

  • Prevalence rates of asthma in developing countries and their comparison with those in Europe and North America.

    abstract::Prevalence rates for asthma in various parts of the world are different and this cannot be entirely explained by differences in methodology. Low prevalence rates are found in third world countries, particularly marked for children. The reasons for these differences are obscure but are largely environmental. Some sugge...


    pub_type: 杂志文章


    authors: Cookson JB

    更新日期:1987-06-01 00:00:00

  • Acute postbronchodilator changes in pulmonary function parameters in patients with chronic airways obstruction.

    abstract::Pulmonary function studies were performed before and after one-time administration of an inhaled bronchodilator to ascertain the relative diagnostic value of using FVC, FEF25-75%, static lung volumes, Raw, and/or sGaw measurements, in addition to the FEV1, to assess the reversibility of chronic airways obstruction in ...


    pub_type: 杂志文章


    authors: Berger R,Smith D

    更新日期:1988-03-01 00:00:00