Abstract:
:Previous work has shown that with increasing airway obstruction in chronic obstructive pulmonary disease, the decrement in the maximum midexpiratory flow (MMEF) is exponential. Therefore, with severe obstructive disease the decrease in the MMEF as the disease progresses is difficult to discern. This work points out that the fall in first second timed vital capacity (FEV1/FVC x 100) is linear through the course of the disease and, therefore, the decrement, in absolute terms, continues unaltered regardless of how severe the obstruction becomes. It is suggested that the FEV1/FVC x 100 might be more useful in monitoring the course of severe disease than the MMEF. However, it is stressed that both measurements are useful for large groups, but may not be useful in individual cases.
journal_name
Chestjournal_title
Chestauthors
Sobol BJ,Emirgil Cdoi
10.1378/chest.72.1.81subject
Has Abstractpub_date
1977-07-01 00:00:00pages
81-3issue
1eissn
0012-3692issn
1931-3543pii
S0012-3692(16)35591-Xjournal_volume
72pub_type
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