Inspiratory capacity and decrease in lung hyperinflation with albuterol in COPD.

Abstract:

STUDY OBJECTIVES:Inspiratory capacity (IC) has been proposed as a simple method to assess acute changes in functional residual capacity (FRC) with bronchodilation, assuming that total lung capacity (TLC) is unchanged. This assumption is based on studies using body plethysmography, which may not accurately measure TLC in severely obstructed subjects. The aim of this study is to validate the use of IC measured by optoelectronic plethysmography (OEP) [ICOEP], a noninvasive technique capable of computing changes in absolute lung volumes with great accuracy. MEWTHODS AND MEASUREMENTS: We studied 13 subjects with COPD in clinically stable condition at baseline and after 200 microg of inhaled albuterol. Changes in lung volumes were obtained from changes in chest wall volume (Vcw) measured by OEP and were compared with those measured by standard techniques. RESULTS:Albuterol treatment caused a small but significant increase in FEV(1) and FVC, a significant decrease of Vcw at FRC (VcwFRC), but no changes of Vcw at TLC (VcwTLC) and breathing pattern variables. The reduction of VcwFRC was not correlated with either spirometric or breathing-pattern variables. IC measured with a pneumotachograph was highly correlated with and not significantly different from ICOEP (p < 0.001). CONCLUSIONS:A single dose of inhaled albuterol does not significantly modify VcwTLC in subjects with COPD, thus validating the use of IC to measure changes of FRC in the assessment of reversibility of airway obstruction.

journal_name

Chest

journal_title

Chest

authors

Duranti R,Filippelli M,Bianchi R,Romagnoli I,Pellegrino R,Brusasco V,Scano G

doi

10.1378/chest.122.6.2009

subject

Has Abstract

pub_date

2002-12-01 00:00:00

pages

2009-14

issue

6

eissn

0012-3692

issn

1931-3543

pii

S0012-3692(15)50819-2

journal_volume

122

pub_type

杂志文章

相关文献

CHEST文献大全
  • Histoplasma capsulatum endocarditis cured by amphotericin B combined with surgery.

    abstract::A patient is reported who had Histoplasma capsulatum endocarditis, a rare form of disseminated histoplasmosis. He also had disseminated intravascular coagulopathy and defects in cell-mediated immune responses to Histoplasma antigens. Prompt etiologic diagnosis was made by stain of tissue from a mouth ulcer and confirm...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.78.5.791

    authors: Bradsher RW,Wickre CG,Savage AM,Harston WE,Alford RH

    更新日期:1980-11-01 00:00:00

  • Disturbed intestinal integrity in patients with COPD: effects of activities of daily living.

    abstract:BACKGROUND:COPD is accepted to be a multicomponent disease with various comorbidities. To our knowledge, the contribution of the GI tract to the systemic manifestation of COPD has never been investigated. This metabolically active organ may experience recurring local oxygen deficits during daily life, leading to distur...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.13-0584

    authors: Rutten EPA,Lenaerts K,Buurman WA,Wouters EFM

    更新日期:2014-02-01 00:00:00

  • Association Between BMI and Obesity With Survival in Pulmonary Arterial Hypertension.

    abstract:BACKGROUND:An obesity paradox, wherein patients who are obese have lower mortality, has been described in cardiopulmonary diseases, including pulmonary arterial hypertension (PAH). Our objective was to determine whether obesity and BMI are associated with mortality in patients with PAH. METHODS:We assessed incident pa...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1016/j.chest.2018.05.006

    authors: Weatherald J,Huertas A,Boucly A,Guignabert C,Taniguchi Y,Adir Y,Jevnikar M,Savale L,Jaïs X,Peng M,Simonneau G,Montani D,Humbert M,Sitbon O

    更新日期:2018-10-01 00:00:00

  • Oral treprostinil for the treatment of pulmonary arterial hypertension in patients on background endothelin receptor antagonist and/or phosphodiesterase type 5 inhibitor therapy (the FREEDOM-C study): a randomized controlled trial.

    abstract:BACKGROUND:Infused and inhaled treprostinil are effective for treatment of pulmonary arterial hypertension (PAH), although their administration routes have limitations. This study assessed the efficacy and safety of bid oral sustained-release treprostinil in the treatment of PAH with a concomitant endothelin receptor a...

    journal_title:Chest

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1378/chest.11-2212

    authors: Tapson VF,Torres F,Kermeen F,Keogh AM,Allen RP,Frantz RP,Badesch DB,Frost AE,Shapiro SM,Laliberte K,Sigman J,Arneson C,Galiè N

    更新日期:2012-12-01 00:00:00

  • Catamenial pneumothorax: a prospective study.

    abstract:OBJECTIVES:To evaluate the incidence of catamenial pneumothorax (CP) among women who have been referred for the surgical treatment of spontaneous pneumothorax (SP) and to study its pathogenic mechanisms. DESIGN:A prospective study of women of reproductive age who have been referred to our center for the surgical treat...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.124.3.1004

    authors: Alifano M,Roth T,Broët SC,Schussler O,Magdeleinat P,Regnard JF

    更新日期:2003-09-01 00:00:00

  • Ventilatory effects of doxapram in conscious human subjects.

    abstract::The ventilatory effects of a bolus intravenous dose of doxapram (0.37 to 0.47 mg/kg) were studied in ten healthy normal subjects. An immediate significant (p less than 0.001) increase in minute ventilation (VE) was due, in equal part, to significant increases in tidal volume (VT) and frequency (f). The inspiratory (TI...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.85.5.600

    authors: Burki NK

    更新日期:1984-05-01 00:00:00

  • Idiopathic hypertrophic subaortic stenosis with ostium secundum atrial septal defect: successful surgical correction.

    abstract::The first report of coincident IHSS and ostium secundum ASD is corroborated and successful septal myotomy and myectomy with patch closure of the ASD is described. ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.68.2.246

    authors: Smith DC,Vieweg WV,Folkerth TL,Hagan AD

    更新日期:1975-08-01 00:00:00

  • Risk of catheter-related bloodstream infection with peripherally inserted central venous catheters used in hospitalized patients.

    abstract:BACKGROUND:Peripherally inserted central venous catheters (PICCs) are now widely used for intermediate and long-term access in current-day health care, especially in the inpatient setting, where they are increasingly supplanting conventional central venous catheters (CVCs) placed percutaneously into the internal jugula...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.128.2.489

    authors: Safdar N,Maki DG

    更新日期:2005-08-01 00:00:00

  • Echocardiographic findings after tricuspid valvectomy.

    abstract::Resection of the tricuspid valve without prosthetic replacement has successfully been performed in patients with tricuspid valvular endocarditis. Using M-mode, two-dimensional, and Doppler echocardiograms, we studied four patients who underwent tricuspid valvectomy. All patients had previous history of intravenous dru...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.87.5.668

    authors: Friedman G,Kronzon I,Nobile J,Cohen ML,Winer HE

    更新日期:1985-05-01 00:00:00

  • Solid or partly solid solitary pulmonary nodules: their characterization using contrast wash-in and morphologic features at helical CT.

    abstract:BACKGROUND:Solitary pulmonary nodule (SPN) evaluation based on analyses of combined wash-in (WI) and washout (WO) values obtained by helical dynamic CT (HDCT) scanning is useful for malignant SPN characterization, because this method has higher specificity and accuracy than that based on analyses of WI values only. How...

    journal_title:Chest

    pub_type: 临床试验,杂志文章

    doi:10.1378/chest.06-2526

    authors: Lee KS,Yi CA,Jeong SY,Jeong YJ,Kim S,Chung MJ,Kim HY,Kim YK,Lee KH

    更新日期:2007-05-01 00:00:00

  • A 56-Year-Old Woman With Multiple Pulmonary Cysts and Severe Chest Pain.

    abstract::A 56-year-old woman presented to our hospital with a 4-month history of worsening chest pain. She denied having any respiratory symptoms, such as dyspnea, sputum, cough, or hemoptysis, or any history of smoking or exposure to dusts. One year previously she had a vertebral fracture. There was no specific family history...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1016/j.chest.2017.12.002

    authors: Kato T,Muto H,Hishima T,Kawashima M,Nagai H,Matsui H,Shimada M,Hebisawa A,Doki N,Miyawaki S,Ohashi K

    更新日期:2018-05-01 00:00:00

  • Evaluation and management of pill aspiration: case discussion and review of the literature.

    abstract::Pill aspiration represents a unique type of foreign body aspiration requiring a distinct diagnostic and therapeutic approach. In many cases, the "foreign body" itself may no longer be present, whereas the airway manifestations may persist for months to years. Limited data exist to guide management decisions. We report...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.12-1571

    authors: Kinsey CM,Folch E,Majid A,Channick CL

    更新日期:2013-06-01 00:00:00

  • The role of hypovolemic stress in the production of fat embolism in rabbits. 1. Morphologic alterations of the lungs.

    abstract::In rabbits, an experimental model of fat embolism was produced that simulates the course of events in the clinical situation. Small doses of fat-cell suspension (0.075 ml/kg of body weight), prepared by collagenase treatment of homologous adipose tissue, were injected intravenously. Concomitantly, hypovolemia was prod...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.69.4.523

    authors: Cotev S,Rosenmann E,Eyal Z,Weinberg H,Shafrir E,Davidson JT

    更新日期:1976-04-01 00:00:00

  • Relationship between the electrical (electrocardiographic) and mechanical (echocardiographic) events in Wolff-Parkinson-White syndrome.

    abstract::Studies using epicardial mapping on patients with Wolff-Parkinson-White syndrome have demonstrated that the delta vector of the electrocardiogram is a detector of the location of at least one bypass tract. In order to relate the electrical activities (preexcitation) with the mechanical activity (septal and ventricular...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.71.4.463

    authors: Lebovitz JA,Mandel WJ,Laks MM,Kraus R,Weinstein S

    更新日期:1977-04-01 00:00:00

  • Distinct characteristics of pleuroparenchymal fibroelastosis with usual interstitial pneumonia compared with idiopathic pulmonary fibrosis.

    abstract:BACKGROUND:Pleuroparenchymal fibroelastosis (PPFE) is a rare form of interstitial pneumonia and sometimes coexists with a histologic usual interstitial pneumonia (UIP) pattern. This study aimed to describe the distinct clinical features of PPFE with UIP pattern compared with idiopathic pulmonary fibrosis (IPF). METHOD...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.13-2866

    authors: Oda T,Ogura T,Kitamura H,Hagiwara E,Baba T,Enomoto Y,Iwasawa T,Okudela K,Takemura T,Sakai F,Hasegawa Y

    更新日期:2014-11-01 00:00:00

  • Lack of efficacy for a cervicomandibular support collar in the management of obstructive sleep apnea.

    abstract:STUDY OBJECTIVES:The effect of therapy using a cervicomandibular support collar (CMSC) to manage obstructive sleep apnea (OSA) was compared with standard therapy, nasal continuous positive airway pressure (nCPAP). DESIGN:Subjects received treatment with CMSC or nCPAP each for 1 month in random order. The study was ana...

    journal_title:Chest

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1378/chest.125.1.118

    authors: Skinner MA,Kingshott RN,Jones DR,Taylor DR

    更新日期:2004-01-01 00:00:00

  • Pneumothorax in the ICU: patient outcomes and prognostic factors.

    abstract:STUDY OBJECTIVE:To identify the prognostic factors for pneumothorax in patients in the ICU. DESIGN:Retrospective cohort study. SETTING:ICU at a university-based teaching hospital. PATIENTS AND METHODS:Sixty patients developed pneumothoraces in the ICU during a period of 36 months. Medical records relating to patient...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.122.2.678

    authors: Chen KY,Jerng JS,Liao WY,Ding LW,Kuo LC,Wang JY,Yang PC

    更新日期:2002-08-01 00:00:00

  • Pulmonary reaction to upper mantle radiation therapy for Hodgkin's disease.

    abstract::To study the effects of upper mantle radiation therapy on pulmonary function, forced expiratory volume in one second (FEV1), vital capacity (VC), inspiratory capacity (IC), diffusing capacity for CO (DLCO) and diffusion per unit of alveolar volume (DL/VA were determined in 28 patients with Hodgkin's disease, stages 1-...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.75.6.688

    authors: do Pico GA,Wiley AL Jr,Rao P,Dickie HA

    更新日期:1979-06-01 00:00:00

  • Pseudoidiopathic hypertrophic subaortic stenosis in a patient with cardiac tamponade.

    abstract::A 53-year-old woman with a large pericardial effusion and tamponade presented with signs of IHSS including a grade 4/6 apical systolic murmur, severe SAM, early systolic aortic valve closure and a small hypercontractile left ventricle but at most borderline left ventricular hypertrophy. Following pericardiocentesis, t...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.91.4.631

    authors: Pandi AS,Kronik G

    更新日期:1987-04-01 00:00:00

  • FVC to slow inspiratory vital capacity ratio: a potential marker for small airways obstruction.

    abstract:BACKGROUND:The ratio of FVC to slow inspiratory vital capacity (SVC) has been reported to reflect small airways obstruction, but its validity as such is still unclear. The aim of this study was to assess the applicability of the FVC/SVC ratio as a marker of small airways function in patients with bronchiolitis oblitera...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.06-2763

    authors: Cohen J,Postma DS,Vink-Klooster K,van der Bij W,Verschuuren E,Ten Hacken NH,Koëter GH,Douma WR

    更新日期:2007-10-01 00:00:00

  • Negative pressure pulmonary edema following bronchospasm.

    abstract::Negative pressure pulmonary edema (NPPE) is an important cause of noncardiogenic pulmonary edema but is rarely reported in the setting of bronchospasm. A 43-year-old woman with severe reactive airway disease suffered an episode of severe bronchospasm after endotracheal extubation following an otherwise uneventful gene...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.11-0529

    authors: Krodel DJ,Bittner EA,Abdulnour RE,Brown RH,Eikermann M

    更新日期:2011-11-01 00:00:00

  • Symptom intensity and subjective limitation to exercise in patients with cardiorespiratory disorders.

    abstract::The aim of the study was to compare (1) the intensity of leg effort and dyspnea during exercise and (2) subjective limitations to performance in normal subjects, patients receiving medication for cardiac disorders, patients with pulmonary impairment, patients with pulmonary impairment who were also receiving cardiac m...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.110.5.1255

    authors: Hamilton AL,Killian KJ,Summers E,Jones NL

    更新日期:1996-11-01 00:00:00

  • Performance of confirmatory interferon-γ release assays in school TB outbreaks.

    abstract:BACKGROUND:Interferon-γ release assays (IGRAs) have been incorporated into several national guidelines for latent TB infection (LTBI) diagnosis. However, their optimal application is still controversial and evolving. The aim of this study is to evaluate the performance of confirmatory IGRAs in addition to tuberculin sk...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.11-1158

    authors: Song S,Jeon D,Kim JW,Kim YD,Kim SP,Cho JS,Lee SE,Cho WH,Park HK,Kim YS,Lee MK,Lee JH

    更新日期:2012-04-01 00:00:00

  • COPD can mimic the appearance of pneumothorax on thoracic ultrasound.

    abstract:PURPOSES:To determine the diagnostic accuracy of ultrasound in the diagnosis of pneumothorax in patients with COPD with particular regard to false-positive diagnoses. MATERIALS AND METHODS:This was a single-center, prospective, blinded study. Nine patients with pneumothorax, 9 patients with cystic fibrosis, 17 patient...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.129.3.545

    authors: Slater A,Goodwin M,Anderson KE,Gleeson FV

    更新日期:2006-03-01 00:00:00

  • Nutritional support for individuals with COPD: a meta-analysis.

    abstract:RATIONALE:Malnutrition in patients with COPD is associated with an impaired pulmonary status, reduced diaphragmatic mass, lower exercise capacity, and higher mortality rate when compared to adequately nourished individuals with COPD. Nutritional support may therefore be a useful part of their comprehensive care. PURPO...

    journal_title:Chest

    pub_type: 临床试验,杂志文章,meta分析,随机对照试验

    doi:10.1378/chest.117.3.672

    authors: Ferreira IM,Brooks D,Lacasse Y,Goldstein RS

    更新日期:2000-03-01 00:00:00

  • Determination of bronchodilation in the clinical pulmonary function laboratory. Role of changes in static lung volumes.

    abstract::Improved airway resistance following bronchodilator inhalation is not always accompanied by improvement in forced expiratory flow. We studied 241 patients with airways obstruction to learn whether changes in static lung volumes (vital capacity and function residual capacity measured by body plethysmography [FRCB]) wou...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.76.6.622

    authors: Ramsdell JW,Tisi GM

    更新日期:1979-12-01 00:00:00

  • Development of a giant bulla after lung volume reduction surgery.

    abstract::Lung volume reduction surgery (LVRS) is being evaluated in the treatment of emphysema. The proposed mechanisms of improvement are increased elastic recoil of the lung and improved mechanical efficiency of the muscles of respiration. We report a unique patient with emphysema who developed a giant bulla 3 years subseque...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.116.6.1809

    authors: Iqbal M,Rossoff L,McKeon K,Graver M,Scharf SM

    更新日期:1999-12-01 00:00:00

  • A 1-year community-based health economic study of ciprofloxacin vs usual antibiotic treatment in acute exacerbations of chronic bronchitis: the Canadian Ciprofloxacin Health Economic Study Group.

    abstract:OBJECTIVE:To evaluate the costs, consequences, effectiveness, and safety of ciprofloxacin vs standard antibiotic care in patients with an initial acute exacerbation of chronic bronchitis (AECB) as well as recurrent AECBs over a 1-year period. DESIGN:Randomized, multicenter, parallel-group, open-label study. SETTING:O...

    journal_title:Chest

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1378/chest.113.1.131

    authors: Grossman R,Mukherjee J,Vaughan D,Eastwood C,Cook R,LaForge J,Lampron N

    更新日期:1998-01-01 00:00:00

  • Gastroesophageal reflux-induced bronchoconstriction. An intraesophageal acid infusion study using state-of-the-art technology.

    abstract:STUDY OBJECTIVE:To study mechanisms of gastroesophageal reflux-induced bronchoconstriction during intraesophageal infusions. DESIGN:Prospective study blinded to the subject. SETTING:Outpatient pulmonary function laboratory at a 908-bed university hospital. PARTICIPANTS:Forty-seven adult subjects divided into four gr...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.106.3.731

    authors: Schan CA,Harding SM,Haile JM,Bradley LA,Richter JE

    更新日期:1994-09-01 00:00:00

  • Interleukin-2 and soluble interleukin-2 receptor in bronchoalveolar lavage fluid from patients with bronchial asthma.

    abstract::To clarify the interrelation between interleukin-2 (IL-2) and soluble IL-2R receptor (sIL-2R), as products of T-cell activation in the bronchial tree of patients with bronchial asthma, we measured the concentration of IL-2, sIL-2R, and the cellular composition in bronchoalveolar lavage (BAL) fluid. We also measured ph...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.106.2.400

    authors: Park CS,Lee SM,Chung SW,Uh S,Kim HT,Kim YH

    更新日期:1994-08-01 00:00:00