The role of open lung biopsy in patients with the acquired immunodeficiency syndrome.

abstract：STUDY OBJECTIVES:To examine the utilization of chemoprophylaxis for tuberculosis in certain high-risk groups, ie, infected contacts 50 years and older, and to study the safety of isoniazid (INH) preventive therapy in such persons. DESIGN:From 1987 to 1992, two-part questionnaires were sent to each of the regional heal...

journal_title：Chest

authors： Sorresso DJ,Mehta JB,Harvill LM,Bentley S

更新日期：1995-09-01 00:00:00

abstract：OBJECTIVES:To evaluate the diagnostic use of pleural fluid adenosine deaminase (ADAPF) levels in tuberculous pleuritis (TBpl), with a special reference to HIV coinfection and a Bayesian analysis. METHODS:We investigated a total of 216 patients with pleural effusion, including 100 with TBpl, 68 with malignant effusion,...

journal_title：Chest

authors： Riantawan P,Chaowalit P,Wongsangiem M,Rojanaraweewong P

更新日期：1999-07-01 00:00:00

abstract：:Histochemical quantification of goblet cells and measurements of the epithelial thickness were made in the trachea of male and female rats exposed to fresh whole tobacco smoke for 30 consecutive days. Exposure to tobacco smoke resulted in an increase in the total goblet cell count in both sexes, with the female rats d...

journal_title：Chest

authors： Hayashi M,Sornberger GC,Huber GL

更新日期：1978-04-01 00:00:00

abstract：:The pathogenesis and clinical manifestations of COPD are not restricted to pulmonary inflammation and structural remodeling. Rather, this disorder is associated with clinically significant systemic alterations in biochemistry and organ function. The systemic aspects of COPD include oxidative stress and altered circula...

journal_title：Chest

authors： Wouters EF,Creutzberg EC,Schols AM

更新日期：2002-05-01 00:00:00

abstract：:A 31-year-old man with legionnaires' disease, who presented with severe pneumonia and hypoxemia, later developed severe bronchospasm and marked hypercapnia, a complication not previously reported in Legionella infection. He responded to therapy with erythromycin and a bronchodilator. ...

journal_title：Chest

authors： Rosenberg DM,Martin L,Lerner P,Parker DM

更新日期：1982-09-01 00:00:00

abstract：:To predict the postoperative improvement in performance status after bullectomy, preoperative pulmonary function and dyspneic grade were evaluated in 20 patients with giant bulla. The patients were divided into two groups, based on postoperative performance status: group 1 consisted of 15 patients with improved status...

journal_title：Chest

authors： Ohta M,Nakahara K,Yasumitsu T,Ohsugi T,Maeda M,Kawashima Y

更新日期：1992-03-01 00:00:00

abstract：:The most examined tumor markers in lung cancer patients are CEA, hormonal peptides, and some neurogenic enzymes in small cell carcinoma. Calcitonin, ACTH, ADH, CEA, neurophysin, oxytocin, beta-endorphin, neuron-specific enolase, and CK BB are elevated in serum specimens in 25-75% of cases of small cell carcinoma. The ...

journal_title：Chest

authors： Hansen M,Pedersen AG

更新日期：1986-04-01 00:00:00

abstract：:Streptococcus pneumoniae has been known for > 100 years as the most important bacterial pathogen of the respiratory tract in adults and children. In recent years, the pneumococcus has begun to exhibit increasing resistance to antimicrobial agents. Because of the huge number of infections caused by this organism, the d...

journal_title：Chest

authors： Harwell JI,Brown RB

更新日期：2000-02-01 00:00:00

abstract：BACKGROUND:It is unclear whether an abnormal swallowing reflex affects COPD exacerbations. This study investigated the prevalence of abnormal swallowing reflexes and its relationship with COPD exacerbation prospectively. We also clarified its association with gastroesophageal reflux disease (GERD) and airway bacterial ...

journal_title：Chest

authors： Terada K,Muro S,Ohara T,Kudo M,Ogawa E,Hoshino Y,Hirai T,Niimi A,Chin K,Mishima M

更新日期：2010-02-01 00:00:00

abstract：STUDY OBJECTIVES:To compare the oxygen pulse curve (O(2)P-C) as measured during cardiopulmonary exercise testing (CPET) with left ventricular (LV) ejection fraction (LVEF) rest-exercise response as measured by multigated equilibrium (99m)Tc radionuclide cineangiography (MUGA) in patients with different degrees of ische...

journal_title：Chest

authors： Klainman E,Fink G,Lebzelter J,Krelbaumm T,Kramer MR

更新日期：2002-03-01 00:00:00

abstract：:The presence of a null gene for alpha1-antitrypsin was detected in a family study by the inheritance of intermediate antitrypsin deficiency in association with a normal (PiM) phenotypic pattern. The proband, a 42-year-old man (M-phenotype), was a cigarette smoker and had physiologic evidence of pulmonary emphysema. Th...

journal_title：Chest

authors： Lieberman J,Gaidults L,Schleissner LA

更新日期：1976-10-01 00:00:00

abstract：:Patients with regionally extensive non-small cell lung cancer (predominantly by virtue of metastases to mediastinal lymph nodes, less commonly by direct extension into the mediastinum) were treated predominantly with chest radiation therapy alone until the early 1980s. At that time, because of the high local recurrenc...

journal_title：Chest

authors： Eagan RT

更新日期：1994-12-01 00:00:00

abstract：:Transesophageal echocardiography (TEE) is a safe and minimally invasive tool that can routinely provide high-quality anatomic and hemodynamic information in the severely ill. Despite its potential for frontline acute care clinicians, TEE use has typically been reserved for diagnostic experts in the cardiac-surgical mi...

journal_title：Chest

authors： Jaidka A,Hobbs H,Koenig S,Millington SJ,Arntfield RT

更新日期：2019-01-01 00:00:00

abstract：:Follow-up of patients with subclinical inflammatory alveolitis associated with systemic diseases may represent the best opportunity to study the mechanisms responsible for the development of interstitial lung disease. We report a seven-year sequential pulmonary evaluation of one patient with clinically isolated gastri...

journal_title：Chest

authors： Dugas M,Wallaert B,Tonnel AB,Voisin C

更新日期：1989-10-01 00:00:00

abstract：:We report an unusual case of a patient with a bronchopleural-subcutaneous fistula that occurred 3 years following a lobectomy and en bloc chest wall resection for carcinoma. Following a sudden resolution of subcutaneous emphysema, an epidural air collection developed. Spontaneous pneumorrhachis is a previously unrepor...

journal_title：Chest

authors： Ristagno RL,Hiratzka LF,Rost RC Jr

更新日期：2002-05-01 00:00:00

abstract：STUDY OBJECTIVES:We investigated the role of two leukotriene B4 (LTB4) receptors, BLT1 and peroxisome proliferator-activated receptor (PPAR)-alpha, in conferring the susceptibility to develop COPD in smokers. Proinflammatory LTB4 activities are mediated by BLT1, while the inactivation of LTB4 is promoted by PPARalpha. ...

journal_title：Chest

authors： Marian E,Baraldo S,Visentin A,Papi A,Saetta M,Fabbri LM,Maestrelli P

更新日期：2006-06-01 00:00:00

abstract：STUDY OBJECTIVE:The chronically critically ill (CCI) are a subgroup of critically ill patients who have survived an acute critical illness but remain profoundly debilitated and ventilator dependent. We have previously shown that CCI patients have a very high prevalence of bone hyperresorption. The objective of this pre...

journal_title：Chest

authors： Nierman DM,Mechanick JI

更新日期：2000-09-01 00:00:00

abstract：:The purpose of this study was to assess the impact of prior cardiac or pulmonary disease upon the utility of ventilation/perfusion (V/Q) scans in the diagnosis of acute pulmonary embolism (PE). Ventilation/perfusion scans were evaluated among 365 patients with no prior cardiac or pulmonary disease and compared to V/Q ...

journal_title：Chest

authors： Stein PD,Coleman RE,Gottschalk A,Saltzman HA,Terrin ML,Weg JG

更新日期：1991-09-01 00:00:00

abstract：PURPOSE:To assess the diagnostic accuracy of the chest radiograph in the evaluation of acute pulmonary complications in immunocompromised patients. METHODS:The study included the chest radiographs in 149 consecutive acute pulmonary complications seen in immunocompromised patients in whom a definitive diagnosis was mad...

journal_title：Chest

authors： Logan PM,Primack SL,Staples C,Miller RR,Müller NL

更新日期：1995-11-01 00:00:00

abstract：OBJECTIVE:This study applies a stochastic or probability search and display model to prospectively predict outcome and to evaluate therapeutic effects in a consecutively monitored series of 396 patients with severe thoracic and thoracoabdominal injuries. STUDY DESIGN:Prospective observational study of outcome predicti...

journal_title：Chest

authors： Shoemaker WC,Bayard DS,Wo CC,Chan LS,Chien LC,Lu K,Jelliffe RW

更新日期：2005-10-01 00:00:00

abstract：:Considerable heterogeneity persists in the conduct and reporting of statistical analyses in the medical literature. Authors submitting manuscripts to CHEST are encouraged to adhere to the following guidelines where possible. ...

journal_title：Chest

authors： Kattan MW,Vickers AJ

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:The burden of children's chronic cough to parents is largely unknown. The objectives of this study were as follows: (1) to determine the burden of chronic cough using a purposely designed questionnaire, and (2) to evaluate psychological (child's anxiety and parental emotional distress) and other influences o...

journal_title：Chest

authors： Marchant JM,Newcombe PA,Juniper EF,Sheffield JK,Stathis SL,Chang AB

更新日期：2008-08-01 00:00:00

abstract：:Ventilator-associated pneumonia (VAP), a major cause of ICU infection, results in high morbidity, mortality, and health-care costs. Multiple risk factors for VAP involve complex host factors and ubiquitous pathogens that require several different types of prevention strategies. Prevention efforts should focus on reduc...

journal_title：Chest

authors： Craven DE

更新日期：2006-07-01 00:00:00

abstract：:A report of pulmonary edema following acute upper airway obstruction in an adult is presented, and the literature involving 25 additional cases is reviewed. This form of pulmonary edema appears to be related to markedly negative intrathoracic pressure due to forced inspiration against a closed upper airway resulting i...

journal_title：Chest

authors： Willms D,Shure D

更新日期：1988-11-01 00:00:00

abstract：STUDY OBJECTIVES:Anastomotic leakage after esophagectomy is associated with high postoperative morbidity and mortality. The most important predisposing factors for anastomotic leaks are ischemia of the gastric conduit and low blood oxygen content. The aim of this study was to evaluate the influence of thoracic epidural...

journal_title：Chest

authors： Michelet P,D'Journo XB,Roch A,Papazian L,Ragni J,Thomas P,Auffray JP

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:The accuracy of combined clinical examination (CE) and chest radiography (CXR) (CE + CXR) vs thoracic ultrasonography in the acute assessment of pneumothorax, hemothorax, and lung contusion in chest trauma patients is unknown. METHODS:We conducted a prospective, observational cohort study involving 119 adul...

journal_title：Chest

authors： Hyacinthe AC,Broux C,Francony G,Genty C,Bouzat P,Jacquot C,Albaladejo P,Ferretti GR,Bosson JL,Payen JF

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:The impact of modern therapy on survival in pulmonary arterial hypertension (PAH) associated with systemic sclerosis (SSc) is not clear. We sought to determine associations among commonly used clinical and hemodynamic variables, treatment, and long-term survival in PAH associated with SSc compared with PAH d...

journal_title：Chest

authors： Rubenfire M,Huffman MD,Krishnan S,Seibold JR,Schiopu E,McLaughlin VV

更新日期：2013-10-01 00:00:00

abstract：:Four patients with elevated creatine phosphokinase (CPK) values and recurrent chest pain were found to have thoracic outlet syndrome. This association of abnormal CPK levels and chest pain due to thoracic outlet syndrome has not been previously reported. Symptoms and CPK values improved with anti-inflammatory medicati...

journal_title：Chest

authors： Godfrey NF,Halter DG,Minna DA,Weiss M,Lorber A

更新日期：1983-03-01 00:00:00

abstract：:Cumulative dose response curves to inhaled methacholine were established in 24 "healthy" children of asthmatic parents and 7 healthy children of healthy parents. Atopic children of asthmatic parents demonstrated higher bronchial hyperreactivity (BHR) than nonatopic children. The BHR was about ten times less than in th...

journal_title：Chest

authors： Bruderman I,Cohen R,Schachter J

更新日期：1990-02-01 00:00:00

abstract：:Respiratory manifestations of systemic lupus erythematosus (SLE) are frequent. They include respiratory muscle abnormalities, which have been implicated in the pathogenesis of the "shrinking lung syndrome" (SLS). We report the case of a patient with this syndrome, in whom diaphragmatic paralysis due to demyelinating p...

journal_title：Chest

authors： Hardy K,Herry I,Attali V,Cadranel J,Similowski T

更新日期：2001-04-01 00:00:00