The drug-resistant pneumococcus: clinical relevance, therapy, and prevention.

abstract：:Caveolae are cell plasma membrane microdomains implicated in organizing and concentrating many signaling molecules. In the lung, caveolae are in endothelium, smooth muscle, fibroblasts, and pneumocytes. Caveolin is the main structural protein of caveolae. Caveolin 1 is down-regulated in transformed cells and may be a ...

journal_title：Chest

authors： Achcar RO,Demura Y,Rai PR,Taraseviciene-Stewart L,Kasper M,Voelkel NF,Cool CD

更新日期：2006-03-01 00:00:00

abstract：:On the occasion of this Fourth World Conference on Lung Cancer, I am privileged to present the opening keynote address. This presentation has been sponsored by the Ontario Cancer Treatment and Research Foundation. In 1952, the Foundation established an annual lectureship in memory of one of their prominent physicians....

journal_title：Chest

authors： Pearson FG

更新日期：1986-04-01 00:00:00

abstract：:The differentiation of ventricular tachycardia from supraventricular conducted with aberration constitutes a perennial challenge. We report a new surface ECG clue, hitherto undescribed, the presence of which, during wide QRS tachycardia, indicates that the tachycardia in question is ventricular rather than supraventri...

journal_title：Chest

authors： Reddy GV,Leghari RU

更新日期：1987-10-01 00:00:00

abstract：:A 66-year-old white woman had a paraffin plombage performed in 1940 for tuberculosis. In 1975, she had decortication for terminal respiratory insufficiency, with return to an active life. Thirty-five years of pulmonary compression does not produce irreversible changes in the pulmonary parenchyma. ...

journal_title：Chest

authors： Knudsen DF

更新日期：1977-05-01 00:00:00

abstract：STUDY OBJECTIVES:Autopsy evaluation of tracheobronchomalacia (TBM) in patients with Duchenne muscular dystrophy (DMD) who were receiving long-term ventilation through uncuffed tracheostomies. DESIGN:Necropsies were performed in seven patients with DMD who had received positive-pressure ventilation through uncuffed tra...

journal_title：Chest

authors： Baydur A,Kanel G

更新日期：2003-04-01 00:00:00

abstract：:Mexiletine is a type 1B antiarrhythmic drug similar to lidocaine. Prolongation of ventricular depolarization has not been previously reported with the usual oral dosage of mexiletine. We describe a patient with renal failure and heart failure on low-dose oral therapy who developed mexiletine toxicity, which was manife...

journal_title：Chest

authors： Nora MO,Chandrasekaran K,Hammill SC,Reeder GS

更新日期：1989-04-01 00:00:00

abstract：:To examine the value of antimyosin-indium 111 imaging in relation to endomyocardial biopsy in patients with suspected myocarditis, as well as the natural evolution of abnormal findings on the antimyosin scan, 12 patients with suspected myocarditis underwent endomyocardial biopsy and antimyosin scan. The heart-to-lung ...

journal_title：Chest

authors： Lekakis J,Nanas J,Moustafellou A,Kostamis P,Moulopoulos S

更新日期：1993-11-01 00:00:00

abstract：:To study the effects of upper mantle radiation therapy on pulmonary function, forced expiratory volume in one second (FEV1), vital capacity (VC), inspiratory capacity (IC), diffusing capacity for CO (DLCO) and diffusion per unit of alveolar volume (DL/VA were determined in 28 patients with Hodgkin's disease, stages 1-...

journal_title：Chest

authors： do Pico GA,Wiley AL Jr,Rao P,Dickie HA

更新日期：1979-06-01 00:00:00

abstract：STUDY OBJECTIVE:To determine if screening by specialists could reduce unnecessary test ordering and reduce costs related to diagnostic workup in patients undergoing evaluation for tuberculosis. DESIGN:Prospective evaluation of expert opinion in consecutive patients suspected of having tuberculosis. SETTING:A large mu...

journal_title：Chest

authors： Divinagracia RM,Harkin TJ,Bonk S,Schluger NW

更新日期：1998-09-01 00:00:00

abstract：OBJECTIVES:A fixed combination of long-acting beta(2)-agonists (LABA) plus inhaled corticosteroids (ICS) has never been proven to reduce asthma exacerbations vs ICS alone in children. This 12-month, double-blind, randomized study in 341 children (age range, 4 to 11 years) with asthma uncontrolled on ICS investigated wh...

journal_title：Chest

authors： Bisgaard H,Le Roux P,Bjåmer D,Dymek A,Vermeulen JH,Hultquist C

更新日期：2006-12-01 00:00:00

abstract：PURPOSE:To assess the diagnostic accuracy of the chest radiograph in the evaluation of acute pulmonary complications in immunocompromised patients. METHODS:The study included the chest radiographs in 149 consecutive acute pulmonary complications seen in immunocompromised patients in whom a definitive diagnosis was mad...

journal_title：Chest

authors： Logan PM,Primack SL,Staples C,Miller RR,Müller NL

更新日期：1995-11-01 00:00:00

abstract：:From 1982 to 1989, ECD was performed on 18 patients suffering from poorly-tolerated massive pulmonary embolism, for whom classic treatments (fibrinolytics and surgery) were impossible. Eleven of these 18 patients immediately improved (S group). This procedure was unsuccessful in other seven patients (F group). Thirtee...

journal_title：Chest

authors： Timsit JF,Reynaud P,Meyer G,Sors H

更新日期：1991-09-01 00:00:00

abstract：BACKGROUND:Pulmonary disease due to Mycobacterium avium complex (MAC-PD) radiographically resembles that due to tuberculosis; it preferentially affects elderly white men with predisposing pulmonary disorders (PDPD). METHODS:Twenty-nine patients with MAC-PD were identified from a community-based population, and the med...

journal_title：Chest

authors： Reich JM,Johnson RE

更新日期：1992-06-01 00:00:00

abstract：:A man with usual interstitial pneumonia (age of onset 58 years) was previously found to have an Ile73Thr (I73T) surfactant protein C (SFTPC) mutation. Genomic DNA from the individual and two daughters (aged 39 and 43 years) was sequenced for the I73T mutation and variations in ATP-binding cassette A3 (ABCA3). All thre...

journal_title：Chest

authors： Crossno PF,Polosukhin VV,Blackwell TS,Johnson JE,Markin C,Moore PE,Worrell JA,Stahlman MT,Phillips JA 3rd,Loyd JE,Cogan JD,Lawson WE

更新日期：2010-04-01 00:00:00

abstract：:The selection of appropriate chemotherapeutic and/or radiation therapy for small cell lung cancer should be done after careful diagnosis and staging workup. A patient with small cell lung cancer is presented and explanation given for each step in diagnosis and staging. ...

journal_title：Chest

authors： O'Donnell WJ

更新日期：1995-06-01 00:00:00

abstract：STUDY OBJECTIVE:In the present study, we evaluated the leukocyte esterase (LE) area of a reagent strip designed for urinalysis for the semiquantitative measurement of the percentage of polymorphonuclear neutrophils (PMNs) in BAL fluid. DESIGN:Prospective. The relative PMN counts (obtained by conventional microscopy an...

journal_title：Chest

authors： Jacobs JA,De Brauwer EI,Cornelissen EI,Drent M

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:Patients with common variable immunodeficiency (CVID) suffer from respiratory infections leading over time to permanent lung damage. Increased radiosensitivity has been described, and clinicians should consider a risk-benefit assessment when ordering a CT scan, in that the exact level of "safe" radiation exp...

journal_title：Chest

authors： Serra G,Milito C,Mitrevski M,Granata G,Martini H,Pesce AM,Sfika I,Bonanni L,Catalano C,Fraioli F,Quinti I

更新日期：2011-12-01 00:00:00

abstract：STUDY OBJECTIVES:To describe the prevalence of parental prompting to smoke (eg, parent requests that their child light the parent's cigarette in his/her own mouth) in a sample of families, and to assess the agreement between child and parent reports of the prompting behaviors. DESIGN, SETTING, AND PARTICIPANTS:A total...

journal_title：Chest

authors： Laniado-Laborín R,Candelaria JI,Villaseñor A,Woodruff SI,Sallis JF

更新日期：2004-02-01 00:00:00

abstract：:The mechanisms leading to rapid changes in arterial blood gas values soon after exercise ends have not been well established. To further study these phenomena, we exercised seven normal male volunteers to exhaustion on a cycle ergometer with a 25-W/min ramped protocol measuring arterial blood gas values, and breath-by...

journal_title：Chest

authors： O'Neill AV,Johnson DC

更新日期：1991-05-01 00:00:00

abstract：:Whole-lung lavage is the only efficient treatment in pulmonary alveolar proteinosis. A 36-year-old woman with severe pulmonary alveolar proteinosis confirmed by video-assisted thoracoscopic lung biopsies underwent repetitive whole-lung lavages without improvement. A modified technique consisting of manual ventilation ...

journal_title：Chest

authors： Bingisser R,Kaplan V,Zollinger A,Russi EW

更新日期：1998-06-01 00:00:00

abstract：:Asthma and COPD are common respiratory diseases that are caused by the interaction of genetic susceptibility with environmental factors. Environmental influences are important in both diseases, and although there are differences in genetic susceptibilities, there are also similarities. Three examples of interest for b...

journal_title：Chest

authors： Meyers DA,Larj MJ,Lange L

更新日期：2004-08-01 00:00:00

abstract：:We evaluated the demographic, medical, and flight characteristics of 1,115 passengers who were routinely referred for preflight medical screening by a major domestic air carrier. The largest category consisted of 892 patients who requested in-flight oxygen therapy for cardiopulmonary conditions, of which COPD and card...

journal_title：Chest

authors： Gong H Jr,Mark JA,Cowan MN

更新日期：1993-09-01 00:00:00

abstract：STUDY OBJECTIVES:To clarify the significance of a functional lung pattern characterized by a decreased vital capacity (VC) and an increased residual volume (RV), but with a normal FEV1/VC ratio. SETTING:A university teaching hospital. SUBJECTS:Patients with bronchial asthma, pulmonary emphysema, and small airways dis...

journal_title：Chest

authors： Stănescu D

更新日期：1999-07-01 00:00:00

abstract：STUDY OBJECTIVE:Childhood exposure to environmental tobacco smoke (ETS) adversely affects dynamic spirometric indexes as a result of combined early life (including in utero) and current exposure to parental smoking. The aim of our study was to investigate the effect of ETS on lung function and to identify the most sens...

journal_title：Chest

authors： Rizzi M,Sergi M,Andreoli A,Pecis M,Bruschi C,Fanfulla F

更新日期：2004-04-01 00:00:00

abstract：:In the case reported, a patient with severe right ventricular failure following coronary revascularization was successfully weaned from cardiopulmonary bypass following creation of an atrial septal defect. This technique facilitated rapid decompression of the failing right ventricle by shunting blood to the more compl...

journal_title：Chest

authors： Swanson MJ,Fabaz AG,Jung JY

更新日期：1987-11-01 00:00:00

abstract：:The disease concept of idiopathic BOOP has emerged from a study of many open lung biopsy cases of diffuse infiltrative lung disease. The histopathologic features of idiopathic BOOP have several components: bronchiolitis obliterans, organizing pneumonia, accumulation of foamy cells in the peripheral air spaces, and int...

journal_title：Chest

authors： Kitaichi M

更新日期：1992-07-01 00:00:00

abstract：:The preoperative physiologic assessment of a patient being considered for surgical resection of lung cancer must consider the immediate perioperative risks from comorbid cardiopulmonary disease, the long-term risks of pulmonary disability, and the threat to survival due to inadequately treated lung cancer. As with any...

journal_title：Chest

authors： Beckles MA,Spiro SG,Colice GL,Rudd RM,American College of Chest Physicians.

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:There is significant heterogeneity within the primary graft dysfunction (PGD) syndrome. We aimed to identify distinct grade 3 PGD phenotypes based on severity of lung dysfunction and patterns of resolution. METHODS:Subjects from the Lung Transplant Outcomes Group (LTOG) cohort study with grade 3 PGD within ...

journal_title：Chest

authors： Shah RJ,Diamond JM,Cantu E,Lee JC,Lederer DJ,Lama VN,Orens J,Weinacker A,Wilkes DS,Bhorade S,Wille KM,Ware LB,Palmer SM,Crespo M,Localio AR,Demissie E,Kawut SM,Bellamy SL,Christie JD

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Interstitial lung disease (ILD) results in high morbidity and health-care utilization. Diagnostic delays remain common and often occur in nonpulmonology settings. Screening for ILD in these settings has the potential to reduce diagnostic delays and improve patient outcomes. RESEARCH QUESTION:This study soug...

journal_title：Chest

authors： Pugashetti JV,Kitich A,Alqalyoobi S,Maynard-Paquette AC,Pritchard D,Graham J,Boctor N,Kulinich A,Lafond E,Foster E,Mendez C,Choudhry S,Chalaoui J,Morisset J,Kadoch M,Oldham JM

更新日期：2020-08-01 00:00:00

abstract：:Inspiratory muscle strength most often is better reflected by sniff Pes than PImax against occlusion. Furthermore, sniff Pes can be estimated noninvasively by the measurement of sniff Pmo in normal subjects and in patients with respiratory muscle weakness. The aim of this study was to compare sniff Pmo and P.PImax to ...

journal_title：Chest

authors： Héritier F,Perret C,Fitting JW

更新日期：1991-07-01 00:00:00