Abstract:
STUDY OBJECTIVES:To clarify the significance of a functional lung pattern characterized by a decreased vital capacity (VC) and an increased residual volume (RV), but with a normal FEV1/VC ratio. SETTING:A university teaching hospital. SUBJECTS:Patients with bronchial asthma, pulmonary emphysema, and small airways disease, and older subjects. MEASUREMENTS:Measurements of static and dynamic lung volumes, diffusing capacity of the lung for carbon monoxide (as measured by the single-breath method), nitrogen slope of the alveolar plateau, and closing volume (as measured by the single-breath O2 test). CONCLUSION:A functional pattern characterized by a decreased VC and FEV1 and increased RV, but with a normal FEV1/VC ratio and total lung capacity, reflects an obstructive impairment of small airways.
journal_name
Chestjournal_title
Chestauthors
Stănescu Ddoi
10.1378/chest.116.1.231subject
Has Abstractpub_date
1999-07-01 00:00:00pages
231-3issue
1eissn
0012-3692issn
1931-3543pii
S0012-3692(15)38178-2journal_volume
116pub_type
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