Azathioprine-associated pulmonary dysfunction.

abstract：:We evaluated the feasibility of utilizing physician assistants as providers of primary care in a medical ICU. After a three-month period of rigorous training, two PAs were assigned to the ICU. Their performance as well as the operation of the ICU over a two-year period was evaluated and compared to two preceding years...

journal_title：Chest

authors： Dubaybo BA,Samson MK,Carlson RW

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:During noninvasive ventilation, nonintentional leaks have a detrimental effect on the efficacy of ventilation. A wide range of industrial masks are available, with intentional leaks of different importance. The potential impact of this variability in intentional leaks on performances of bilevel ventilators h...

journal_title：Chest

authors： Borel JC,Sabil A,Janssens JP,Couteau M,Boulon L,Lévy P,Pépin JL

更新日期：2009-03-01 00:00:00

abstract：:Cardiac dysfunction due to systemic sarcoidosis is most of ten due to severe restrictive pulmonary diseases. Although the diagnosis is frequently missed during life, direct granulomatous infiltration of the myocardium may occur with systemic sarcoidosis and, when present in the heart, is a major cause of death. To exp...

journal_title：Chest

authors： Bulkley BH,Rouleau JR,Whitaker JQ,Strauss HW,Pitt B

更新日期：1977-07-01 00:00:00

abstract：:Following an outline that details the pathogens causing community-acquired pneumonia (CAP) identified in studies from Europe, this article reviews the guidelines for the management of CAP in four European countries--France, Italy, Spain, and the United Kingdom. The method behind the development of each document is des...

journal_title：Chest

authors： Woodhead M

更新日期：1998-03-01 00:00:00

abstract：:Human genetic variation has enormous implications for individual susceptibility to lung disease, as well as for differences in prognosis and response to therapeutic interventions. Single-nucleotide polymorphisms (SNPs) are the most common type of DNA sequence variation. An SNP is the substitution of a single base in t...

journal_title：Chest

authors： Tebbutt SJ,James A,Paré PD

更新日期：2007-04-01 00:00:00

abstract：:A man with primary lung cancer developed respiratory failure due to lymphangitis carcinomatosis that was diagnosed by transbronchial lung biopsy specimen. After combination chemotherapy with high-dose etoposide and cisplatin (CDDP), he was able to cease oxygen therapy and showed improvement of his lymphangitis carcino...

journal_title：Chest

authors： Fujita J,Yamagishi Y,Kubo A,Takigawa K,Yamaji Y,Takahara J

更新日期：1993-03-01 00:00:00

abstract：:A 42-year-old woman with an anomalous left coronary artery originating from the pulmonary artery and a fistula from the left coronary artery to the left ventricle was treated by aortocoronary bypass grafting of an autologous saphenous vein. The presence of an abundant collateral circulation and of fistulous communicat...

journal_title：Chest

authors： Krajcer Z,Leachman RD,Lufschanowski R,Cooley DA,Angelini P

更新日期：1978-07-01 00:00:00

abstract：BACKGROUND:When evaluating peripheral pulmonary lesions, a 3.0-mm ultrathin bronchoscope (UTB) with a 1.7-mm working channel is advantageous regarding good access to the peripheral airway, whereas a 4.0-mm thin bronchoscope provides a larger 2.0-mm working channel, which allows the use of various instruments including ...

journal_title：Chest

authors： Oki M,Saka H,Asano F,Kitagawa C,Kogure Y,Tsuzuku A,Ando M

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Disease-specific patient-reported outcome (PRO) instruments are important in assessing the impact of disease and treatment. The Pulmonary Arterial Hypertension-Symptoms and Impact Questionnaire is the first instrument for quantifying pulmonary arterial hypertension (PAH) symptoms and impacts developed accord...

journal_title：Chest

authors： Chin KM,Gomberg-Maitland M,Channick RN,Cuttica MJ,Fischer A,Frantz RP,Hunsche E,Kleinman L,McConnell JW,McLaughlin VV,Miller CE,Zamanian RT,Zastrow MS,Badesch DB

更新日期：2018-10-01 00:00:00

abstract：STUDY OBJECTIVES:To describe the prevalence of parental prompting to smoke (eg, parent requests that their child light the parent's cigarette in his/her own mouth) in a sample of families, and to assess the agreement between child and parent reports of the prompting behaviors. DESIGN, SETTING, AND PARTICIPANTS:A total...

journal_title：Chest

authors： Laniado-Laborín R,Candelaria JI,Villaseñor A,Woodruff SI,Sallis JF

更新日期：2004-02-01 00:00:00

abstract：:To assess the clinical correlates and therapeutic outcome of new postoperative supraventricular tachyarrhythmias, 916 patients who were in sinus rhythm throughout the course of surgery were prospectively followed after major noncardiac surgery. The 35 patients (4 percent) who developed new postoperative supraventricul...

journal_title：Chest

authors： Goldman L

更新日期：1978-04-01 00:00:00

abstract：STUDY OBJECTIVES:To investigate the efficacy and safety of amiodarone administered as the drug of first choice in the conversion of atrial fibrillation, regardless of its duration. DESIGN:: Prospective, randomized, controlled clinical study. SETTING:: Tertiary cardiac referral center. PATIENTS:Two-hundred eight cons...

journal_title：Chest

authors： Vardas PE,Kochiadakis GE,Igoumenidis NE,Tsatsakis AM,Simantirakis EN,Chlouverakis GI

更新日期：2000-06-01 00:00:00

abstract：:Antemortem diagnosis of a perforated MV aneurysm by Doppler echocardiography, as well as two-dimensional echocardiography (2-DE), has not been reported. Herein we present such a case. ...

journal_title：Chest

authors： Chua SO,Chiang CW,Lee YS,Chang CH,Hung JS

更新日期：1990-03-01 00:00:00

abstract：BACKGROUND:FEV1 may remain stable while high-resolution CT (HRCT) appearances deteriorate in children with cystic fibrosis (CF). However, spirometry results commonly decline in older age groups. OBJECTIVES:To compare the rate of decline in HRCT abnormalities and spirometry results over time in an adult cohort with CF....

journal_title：Chest

authors： Judge EP,Dodd JD,Masterson JB,Gallagher CG

更新日期：2006-11-01 00:00:00

abstract：:Care of ventilator-dependent patients requires considerable resources, yet the long-term outcomes of this type of care have rarely been described. We retrospectively investigated the posthospital course of elderly patients who survived an episode of prolonged ventilator dependency to describe survival rates, subsequen...

journal_title：Chest

authors： Elpern EH,Larson R,Douglass P,Rosen RL,Bone RC

更新日期：1989-11-01 00:00:00

abstract：:The concentrations of gentamicin, netilmicin, and amikacin were determined after one single intravenous injection in uninfected pleural fluid after thoracotomy and in purulent pleural empyemas. The mean peak concentrations in the pleural fluid after the injection of gentamicin (1.5 mg/kg), netilmicin (2.0 mg/kg), and ...

journal_title：Chest

authors： Thys JP,Vanderhoeft P,Herchuelz A,Bergmann P,Yourassowsky E

更新日期：1988-03-01 00:00:00

abstract：:Norepinephrine, an alpha 1,2-beta 1,2-adrenergic agonist, seems to be an alternative to epinephrine, an alpha 1,2-beta 1,2-agonist, for restoration of spontaneous circulation in VF. We therefore studied the effect of epinephrine and norepinephrine on MDO2 and MVO2 using OCCM after five minutes of cardiopulmonary arres...

journal_title：Chest

authors： Lindner KH,Ahnefeld FW,Schuermann W,Bowdler IM

更新日期：1990-06-01 00:00:00

abstract：BACKGROUND:Although alveolar epithelial injury is a major determinant of outcome in patients with acute lung injury, there is no reliable biological marker of alveolar epithelial injury. The primary objective was to determine whether elevated levels of the receptor for advanced glycation end products (RAGE), a marker o...

journal_title：Chest

authors： Briot R,Frank JA,Uchida T,Lee JW,Calfee CS,Matthay MA

更新日期：2009-02-01 00:00:00

abstract：:Endobronchial tuberculosis, while relatively common before the advent of effective antituberculosis chemotherapy, is seldom recognized now. Four patients with what appeared to be primary tuberculosis complicated by endobronchial spread were recently seen by us. Three of the four patients presented with anterior segmen...

journal_title：Chest

authors： Matthews JI,Matarese SL,Carpenter JL

更新日期：1984-10-01 00:00:00

abstract：:The ipsilateral recurrence rate after the first spontaneous pneumothorax treated with tube thoracostomy is reported to be between 23 percent and 52 percent. The incidence of recurrence after the first recurrence is substantially higher. Chemical pleurodesis has been attempted to decrease the recurrence rate. Tetracycl...

journal_title：Chest

authors： Milanez JR,Vargas FS,Filomeno LT,Fernandez A,Jatene A,Light RW

更新日期：1994-10-01 00:00:00

abstract：OBJECTIVE:To describe the clinical correlates of asthma in a community-based sample of elderly persons. PARTICIPANTS:A community sample of 4,581 persons > or = 65 years old from the Cardiovascular Health Study. MEASUREMENTS:Standardized respiratory, sleep, and quality-of-life (QOL) questions, a medication inventory, ...

journal_title：Chest

authors： Enright PL,McClelland RL,Newman AB,Gottlieb DJ,Lebowitz MD

更新日期：1999-09-01 00:00:00

abstract：BACKGROUND:Vasoactive medications are commonly used in the treatment of critically ill patients, but their impact on the development of ICU-acquired weakness is not well described. The objective of this study is to evaluate the relationship between vasoactive medication use and the outcome of ICU-acquired weakness. ME...

journal_title：Chest

authors： Wolfe KS,Patel BK,MacKenzie EL,Giovanni SP,Pohlman AS,Churpek MM,Hall JB,Kress JP

更新日期：2018-10-01 00:00:00

abstract：STUDY OBJECTIVES:To determine the selective vasodilatory effects of two inhaled "NONOate" aerosols in a closed chest pig model of acute pulmonary hypertension (APH). METHODS:APH was induced by IV infusion of the prostaglandin H(2)/thromboxane A(2) receptor agonist (U46619). Aerosolized diethylenetriamine nitric oxide ...

journal_title：Chest

authors： Lam CF,van Heerden PV,Ilett KF,Caterina P,Filion P

更新日期：2003-03-01 00:00:00

abstract：STUDY OBJECTIVE:We analyze the within-subject variation of mouth occlusion pressure (P0.1) response to progressive isocapnic hypoxic stimulation over long time periods in normal subjects. PATIENTS AND INTERVENTIONS:We studied 21 healthy subjects (14 male and 7 female; aged 40+/-12 yrs) (mean+/-SD). Lung volumes, basal...

journal_title：Chest

authors： García-Río F,Pino-García JM,Racionero MA,Terreros-Caro JG,Gómez-Mendieta MA,Prados C,Villasante C

更新日期：1998-08-01 00:00:00

abstract：STUDY OBJECTIVE:This study aimed to determine the differences between ciliary beat frequencies of respiratory ciliated cells from peripheral bronchioles and from proximal bronchi in humans. DESIGN:Measurements were made from resected lungs. Ciliated cells were harvested by brushing the mucosa of each site immediately ...

journal_title：Chest

authors： Clary-Meinesz C,Mouroux J,Huitorel P,Cosson J,Schoevaert D,Blaive B

更新日期：1997-03-01 00:00:00

abstract：STUDY OBJECTIVES:We report on the long-term safety and efficacy of bosentan treatment in patients with pulmonary arterial hypertension (PAH). BACKGROUND:In a preceding study, bosentan was well tolerated and significantly improved the exercise capacity and hemodynamics of patients with PAH after 12 weeks of treatment. ...

journal_title：Chest

authors： Sitbon O,Badesch DB,Channick RN,Frost A,Robbins IM,Simonneau G,Tapson VF,Rubin LJ

更新日期：2003-07-01 00:00:00

abstract：:We report two cases of pneumothorax detected by echographic examination immediately after ultrasonically guided aspiration biopsy and confirmed by chest x-ray film. The pneumothorax was characterized by the disappearance of the lung tumor. In the real-time image, the respiratory excursions of the visceral pleura also ...

journal_title：Chest

authors： Targhetta R,Bourgeois JM,Chavagneux R,Balmes P

更新日期：1992-03-01 00:00:00

abstract：STUDY OBJECTIVES:To determine if Asian immigrants to the United States present with more advanced lung cancer compared to non-Asians. DESIGN:A 5-year retrospective case-control study (January 1, 1992, to December 31, 1996) of patients with lung cancer identified using the New England Medical Center cancer center datab...

journal_title：Chest

authors： Finlay GA,Joseph B,Rodrigues CR,Griffith J,White AC

更新日期：2002-12-01 00:00:00

abstract：:This is the first reported case of discrete fibrous subaortic stenosis in tetralogy of Fallot. Transaortic excision of the subaortic membrane was readily accomplished. To detect this and other forms of left ventricular outflow-tract obstruction in tetralogy of Fallot before surgery, routine selective left ventriculogr...

journal_title：Chest

authors： Sanders JH,Van Praagh R,Sade RM

更新日期：1976-04-01 00:00:00

abstract：:Diurnal variability of peak expiratory flow rates (PEFRs) was assessed in 1,237 children. The PEFR was measured twice daily over a 1-week period. As an index of variability, the log of a week's mean of daily amplitude was calculated. Linear regression analyses revealed a significant positive association between matern...

journal_title：Chest

authors： Frischer T,Kühr J,Meinert R,Karmaus W,Urbanek R

更新日期：1993-10-01 00:00:00