Identification of early interstitial lung disease in an individual with genetic variations in ABCA3 and SFTPC.

abstract：:Left hemorrhagic pleural effusion was the presenting sign of painless aortic dissecting aneurysm in two elderly hypertensive patients. Computed tomography (CT) of the chest revealed the aneurysmal dilatation of the thoracic aorta and an intimal flap connecting its descending part with the left pleural space. The patie...

journal_title：Chest

authors： Gandelman G,Barzilay N,Krupsky M,Resnitzky P

更新日期：1994-08-01 00:00:00

abstract：CONTEXT:Few studies have examined the effect of nicotine replacement therapy (NRT) in COPD patients. STUDY OBJECTIVE:To evaluate the efficacy of nicotine sublingual tablets and two levels of support for smoking cessation in COPD patients. DESIGN:Double-blind, multicenter, placebo-controlled smoking cessation trial. ...

journal_title：Chest

authors： Tønnesen P,Mikkelsen K,Bremann L

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:The efficacy of a new pharmacologic agent for asthma, in this instance the leukotriene receptor antagonist montelukast, is determined in controlled trials in research subjects. The utility of a new drug is determined by multiple uncontrollable factors in individual patients. OBJECTIVE:To assess the utility ...

journal_title：Chest

authors： Mathison DA,Koziol JA

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND:Contemporary clinical risk stratification schemata for predicting stroke and thromboembolism (TE) in patients with atrial fibrillation (AF) are largely derived from risk factors identified from trial cohorts. Thus, many potential risk factors have not been included. METHODS:We refined the 2006 Birmingham/Na...

journal_title：Chest

authors： Lip GY,Nieuwlaat R,Pisters R,Lane DA,Crijns HJ

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:Bronchiectasis and pulmonary infection with nontuberculous mycobacteria (NTM) may be associated with disease-causing mutations in the cystic fibrosis transmembrane regulator (CFTR). METHODS:Fifty adult patients at Stanford University Medical Center with a diagnosis of bronchiectasis and/or pulmonary NTM inf...

journal_title：Chest

authors： Ziedalski TM,Kao PN,Henig NR,Jacobs SS,Ruoss SJ

更新日期：2006-10-01 00:00:00

abstract：STUDY OBJECTIVE:Data on the prevalence of myocarditis in children are limited. Autopsy studies have shown that myocarditis is often undiagnosed. We attempted to investigate the clinical features of asymptomatic myocarditis in four schoolchildren detected during a mass ECG screening in schoolchildren. DESIGN AND SETTIN...

journal_title：Chest

authors： Nakagawa M,Sato A,Okagawa H,Kondo M,Okuno M,Takamatsu T

更新日期：1999-08-01 00:00:00

abstract：:Transforming growth factor (TGF)-beta is a multifunctional protein that initiates its diverse cellular responses by binding to and activating specific type I and type II serine/threonine kinase receptors. TGF-beta can act as a regulator of proliferation, migration, survival, differentiation, and extracellular matrix s...

journal_title：Chest

authors： Bertolino P,Deckers M,Lebrin F,ten Dijke P

更新日期：2005-12-01 00:00:00

abstract：:Although metastatic carcinoma from an unknown primary tumor is known to occur, the combination of squamous cell carcinoma histologic findings and a mediastinal location is quite unusual. The evaluation of a case of a patient with a posterior mediastinal mass, eventually shown to be metastatic squamous cell carcinoma o...

journal_title：Chest

authors： Blanco N,Kirgan DM,Little AG

更新日期：1998-09-01 00:00:00

abstract：:A 66-year-old white woman had a paraffin plombage performed in 1940 for tuberculosis. In 1975, she had decortication for terminal respiratory insufficiency, with return to an active life. Thirty-five years of pulmonary compression does not produce irreversible changes in the pulmonary parenchyma. ...

journal_title：Chest

authors： Knudsen DF

更新日期：1977-05-01 00:00:00

abstract：BACKGROUND:Acute myopathy following mechanical ventilation for near-fatal asthma (NFA) has been described recently, and some researchers have suggested that this complication is related to the use of neuromuscular blocking agents (NMBAs) and corticosteroids (CSs). OBJECTIVES:To determine the incidence of acute myopath...

journal_title：Chest

authors： Behbehani NA,Al-Mane F,D'yachkova Y,Paré P,FitzGerald JM

更新日期：1999-06-01 00:00:00

abstract：BACKGROUND:This study reports the effect of thoracentesis on respiratory mechanics and gas exchange in patients receiving mechanical ventilation. STUDY DESIGN:Prospective. SETTING:University hospital. PATIENTS:Eight patient receiving mechanical ventilation with unilateral (n = 7) or bilateral (n = 1) large pleural e...

journal_title：Chest

authors： Doelken P,Abreu R,Sahn SA,Mayo PH

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:The leading cause of pericardial effusion in urban hospitals is now AIDS-related pathologies. Clinically, these effusions are a diagnostic and management dilemma. In our institution, pericardial biopsy and operative drainage have become part of the diagnostic and management plan. Surgical intervention, howev...

journal_title：Chest

authors： Flum DR,McGinn JT Jr,Tyras DH

更新日期：1995-06-01 00:00:00

abstract：:The management of intractable hemoptysis, short of surgery, is poorly defined. A technique is described utilizing a bronchofiberscope and a Fogarty catheter that not only provides visualization of the source of bleeding, but also furnishes a means of controlling the bleeding. This technique can also be used through a ...

journal_title：Chest

authors： Gottlieb LS,Hillberg R

更新日期：1975-04-01 00:00:00

abstract：:As seen in this CME online activity (available at http://courses.elseviercme.com/694), idiopathic pulmonary fibrosis (IPF) is a specific form of chronic, progressive, fibrotic lung disease of unknown cause that is associated with substantial health-care utilization and high rates of mortality. The clinical symptoms of...

journal_title：Chest

authors： Martinez FJ,Lederer DJ

更新日期：2018-10-01 00:00:00

abstract：:We reviewed the inpatient records of 139 adult patients with leukemia to determine the incidence of opportunistic infections in immunocompromised patients and the pattern of roentgenographic involvement of such infections. There were 98 parenchymal infiltrates identified, including 43 episodes of local disease and 55 ...

journal_title：Chest

authors： Tenholder MF,Hooper RG

更新日期：1980-09-01 00:00:00

abstract：BACKGROUND:Club cell secretory protein (CCSP) is a protective biomarker associated with annual decline in lung function. COPD progression results from an imbalance between injury and repair initially triggered by cigarette smoking. OBJECTIVE:We investigated the effect of CCSP as a therapeutic strategy to restore the b...

journal_title：Chest

authors： Gamez AS,Gras D,Petit A,Knabe L,Molinari N,Vachier I,Chanez P,Bourdin A

更新日期：2015-06-01 00:00:00

abstract：:Endomyocardial fibrosis (EMF) is a fascinating disease entity of unknown etiology. It is prevalent in the tropical zone. Its essential features are the formation of fibrous tissue on the endocardium and to a lesser extent in the myocardium of the inflow tract and apex of one or both ventricles. It results in endocardi...

journal_title：Chest

authors： Hassan WM,Fawzy ME,Al Helaly S,Hegazy H,Malik S

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:The tumor microenvironment, of which cancer-associated fibroblasts (CAFs) and tumor-associated macrophages (TAMs) are the major cellular components, plays an important role in tumor progression. This study evaluated the significance of podoplanin-positive CAFs and CD204-positive TAMs, which may reflect tumor...

journal_title：Chest

authors： Ito M,Ishii G,Nagai K,Maeda R,Nakano Y,Ochiai A

更新日期：2012-07-01 00:00:00

abstract：:A female patient was treated with high-dose inhaled fluticasone propionate for her asthma. Over 2 years, she developed features of Cushing's syndrome with proximal myopathy, osteopenia, hypertension, depressive psychosis, and cushingoid appearance. She had biochemical evidence of marked adrenal suppression with a 9:00...

journal_title：Chest

authors： Wilson AM,Blumsohn A,Jung RT,Lipworth BJ

更新日期：2000-02-01 00:00:00

abstract：:The spectrum of pathogens and the microbiologic investigations used to obtain a diagnosis in 178 patients with severe pneumonia (88 percent requiring intermittent positive-pressure ventilation) are reviewed. Ninety-five patients had primary pneumonia, 31 had nosocomial pneumonia, 24 were immunocompromised patients, an...

journal_title：Chest

authors： Potgieter PD,Hammond JM

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:The optimal antithrombotic therapy strategy for atrial fibrillation (AF) patients who undergo percutaneous coronary intervention with stent implantation (PCI-S) is unknown. We assessed the safety of antithrombotic therapy strategies in AF patients with indication for oral anticoagulation (OAC) undergoing PCI...

journal_title：Chest

authors： Manzano-Fernández S,Pastor FJ,Marín F,Cambronero F,Caro C,Pascual-Figal DA,Garrido IP,Pinar E,Valdés M,Lip GYH

更新日期：2008-09-01 00:00:00

abstract：:Significant eosinophilia is a prominent feature in Churg-Strauss syndrome but has only rarely been described in Wegener's granulomatosis (WG). We describe two Wegener's granulomatosis patients with > 30% eosinophilia on their initial presentations. Other etiologies that could account for their eosinophilia were exclud...

journal_title：Chest

authors： Potter MB,Fincher RK,Finger DR

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND:Phenotypic characterization of patients with COPD may have potential prognostic and therapeutic implications. Available information on the relationship between emphysema and the clinical presentation in patients with COPD is limited to advanced stages of the disease. The objective of this study was to descri...

journal_title：Chest

authors： de Torres JP,Bastarrika G,Zagaceta J,Sáiz-Mendiguren R,Alcaide AB,Seijo LM,Montes U,Campo A,Zulueta JJ

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Stress-induced or tako-tsubo cardiomyopathy (TTC) is a rare acute cardiac syndrome characterized by transient left ventricular (LV) dysfunction of uncertain cause and outcome. This study sought to assess the long-term outcome of patients with TTC. METHODS:One-hundred sixteen consecutive patients were prospe...

journal_title：Chest

authors： Parodi G,Bellandi B,Del Pace S,Barchielli A,Zampini L,Velluzzi S,Carrabba N,Gensini GF,Antoniucci D,Tuscany Registry of Tako-Tsubo Cardiomyopathy.

更新日期：2011-04-01 00:00:00

abstract：STUDY OBJECTIVES:(1) To determine physician preferences in the management of warfarin-induced excessive anticoagulation (AC); and (2) to assess compliance with the American College of Chest Physicians (ACCP) guidelines for the reversal of excessive AC. DESIGN:Cross-sectional physician survey. PARTICIPANTS:Members of ...

journal_title：Chest

authors： Wilson SE,Douketis JD,Crowther MA

更新日期：2001-12-01 00:00:00

abstract：OBJECTIVES:To review statistics on smoking prevalence and to analyze whether the implementation of national tobacco control legislation had an association with the prevalence of smoking, and thereby, with the occurrence of smoking-related lung diseases. DESIGN:Smoking prevalence rates (from 1960 to 2000), lung cancer ...

journal_title：Chest

authors： Heloma A,Nurminen M,Reijula K,Rantanen J

更新日期：2004-12-01 00:00:00

abstract：:Administration of glucagon has been shown to decrease pulmonary vascular resistance, but its primary site of action is undetermined. Whether this is on the arterial or venous side of the capillary would be reflected in the microvascular hydrostatic pressure. We used the pulmonary flow of lymph, a sensitive index of th...

journal_title：Chest

authors： Demling RH,Manohar M,Will J

更新日期：1978-08-01 00:00:00

abstract：STUDY OBJECTIVE:The tuberculin skin test is the best diagnostic method to detect tuberculous infection. How accurate is interpretation of the test? DESIGN:Observational study. SETTING:Both general hospital and university hospital. PARTICIPANTS:One hundred seven health-care professionals, including 52 practicing pedi...

journal_title：Chest

authors： Kendig EL Jr,Kirkpatrick BV,Carter WH,Hill FA,Caldwell K,Entwistle M

更新日期：1998-05-01 00:00:00

abstract：STUDY OBJECTIVE:We analyze the within-subject variation of mouth occlusion pressure (P0.1) response to progressive isocapnic hypoxic stimulation over long time periods in normal subjects. PATIENTS AND INTERVENTIONS:We studied 21 healthy subjects (14 male and 7 female; aged 40+/-12 yrs) (mean+/-SD). Lung volumes, basal...

journal_title：Chest

authors： García-Río F,Pino-García JM,Racionero MA,Terreros-Caro JG,Gómez-Mendieta MA,Prados C,Villasante C

更新日期：1998-08-01 00:00:00

abstract：BACKGROUND:Chronic tobacco smoke exposure results in a broad range of lung pathologies including emphysema, airway disease and parenchymal fibrosis as well as a multitude of extra-pulmonary comorbidities. Prior work using CT imaging has identified several clinically relevant subgroups of smoking related lung disease, b...

journal_title：Chest

authors： Billatos E,Ash SY,Duan F,Xu K,Romanoff J,Marques H,Moses E,Han MK,Regan EA,Bowler RP,Mason SE,Doyle TJ,San José Estépar R,Rosas IO,Ross JC,Xiao X,Liu H,Liu G,Sukumar G,Wilkerson M,Dalgard C,Stevenson C,Whitney

更新日期：2020-09-16 00:00:00